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1. Innovations in Cocoa Production, Aqua-farming High Nutrition Food Production, Infant Formulas, and Stevia Taster
2. Innovations in Manufacturing of Eco-friendly Composite Materials, Fertilizers, Diamonds, and Inks
3. Innovations in Food Preservation and Food Processing
4. Innovations in Water Quality Monitoring, Biofuels, Bioadhesives, and Biochemicals
5. Innovations in Waste Management
6. Innovations in Prebiotics and Probiotics for Skin Care Cosmetics
7. Innovations in Processing and Manufacturing of Biofuels and Chemicals
8. Innovations in Seed and Fertilizer Treatment, Recycling Plastics, Clothing Dye, and Baby Food Preservation
9. Innovations in Bio-solar Cells, Bio-fertilizers, Carbon dioxide Capture and Utilization, and Smart Water Systems
10. Innovations in Essential Oils, Biofuels, Indoor Farming Systems, and Biochemicals
11. Innovations in Sustainable Waste Management
12. Innovations in Skin Care, Biodegradability, Food Shelf-life Extension, and Food Quality Analysis
13. Innovations in Smart Water Systems
14. Innovations in Organ Bio-fabrication, Waste Management, and Artificial Photosynthesis
15. Innovations in Butter, Chocolate, Wine Storage, Precision Farming, and Food Preservation
16. Innovations in Textile Manufacturing, Biosensor, Biofuel, and Biochemical Production
17. Innovations in Non-thermal Plasma Treatment for Food and Textiles
18. Technology Advances in Prebiotic Additives
19. Innovations in Biofuel and Biochemical Production, Bio-based Packaging, and Bioplastics
20. Innovations in Bio-filtration, Biofuel and Dietary Supplements Production, and Textile Dyeing Processes
Industrial Bioprocessing provides you with the latest intelligence in the
industrial bioprocessing field, including new processes to develop specialty
chemicals, pharmaceuticals, alternative fuels, and chemical feedstocks. Each
week, Industrial Bioprocessing presents you with the latest news on R&D, new
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Throughout the emphasis is on opportunities for you to enhance your business
position by applying bioprocessing solutions to industrial problems. Each
briefing is followed with contact information to assist you in setting up
licensing, partnering, joint venturing, and technology transfer arrangements.
Regular monthly features include:
* Market Forecast - looks at an important industrial sector with expert
forecasts of markets, demand and growth rates.
* Company to Watch - highlights a biotech company on the brink of making a
strong market impact.Patents - presents key patents to show the latest trends
in intellectual property.
ENZYME IS ACTIVE AT SOLVENT/WATER INTERFACE
Along with the growing interest in enzymatic biosynthesis is the increased
popularity of two-phase liquid reaction systems. These systems make it possible
to optimize the culture of microorganisms in an aqueous environment while
carrying out the reaction efficiently in an organic solvent in which the
reactants and products are dissolved. While a great deal is known about enzyme
adsorption at air/liquid and solid/liquid interfaces, much less is known about
enzymatic behavior at the interfaces of two liquids. Harvey Blanch, C. J. Radke,
and Andrea Hickel of the University of California, Berkeley, have done something
to remedy this situation.
They investigated the activity of hydroxynitrile lyase at the interface
between diisopropyl ether (DIPE) and water ("Biotechnol Bioeng" 65:
425-436). The enzyme comes from the almond tree, Prunus amygdalus. Chemical
industry interest in hydroxynitrile lyase enzymes has increased recently because
of their ability to transform chiral cyanohydrins.
However, industrial-scale use of the enzyme faces several difficulties. When
used in the aqueous phase the enantiomerical purity of the product drops, the
enzyme is unstable at low pH, and it isn't available in large quantities. A
two-phase liquid system could be the solution to these problems.
The researchers designed a cylindrical glass recycle reactor to follow the
change of the enzyme's activity in cleaving mandelonitrile to form benzaldehyde.
The exact area of the liquid/liquid interface is known. Activity can be measured
by product formation. Substrate and product are dissolved in the top, DIPE
liquid layer. The enzyme is in the aqueous buffer solution that forms the lower
layer. The DIPE layer is recycled through an optical cell where product can be
measured by UV spectroscopy.
They found that the enzyme adsorbs at the interface and is extremely stable.
It isn't denatured over a period of several hours, although the increase in
surface pressure shows that the enzyme is penetrating the interface.
Investigation shows that the enzymatic reaction takes place at the interface
and not in the aqueous bulk phase. So the most obvious practical knowledge that
comes out of this very basic research is that to design an efficient reactor the
area of the interface must be large.
Sample Weekly Table of Contents
* ENZYME IS ACTIVE AT SOLVENT/WATER INTERFACE
* BIOSCIENCE GETS DAMAGED WASTEWATER PLANT BACK UP
* CHEAPER HYDROGEN WITH SYNTHETIC ENZYME
* AROMATIC POLYCARBONATES BY ENZYMATIC REACTION
* NATIONAL STARCH AND EXCELSIOR PART WAYS
* PROCESS CONVERTS WASTE INTO FEED MATERIAL
* CONTROLLED FED-BATCH PROCESS DEGRADES PHENOL
* SOME IMPORTANT PATENTS FOR YOU TO CHECK