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시장보고서

Proteomics: Current State and Future Directions

리서치사 Insight Pharma Reports
발행일 2006년 09월 상품코드 45495
페이지 정보 65 pages
가격
US $ 2,500 ￦ 2,978,700 PDF by E-mail (Single Site Multi-User License)
US $ 5,000 ￦ 5,957,500 PDF by E-mail (Corporate Use License)


영문목차

Abstract

Proteomics is a rapidly evolving field that is rife with commercial opportunities as the technology achieves ever higher throughput at lower cost and greater sensitivity. Proteomics: Current State and Future Directions is a new CHA Advances report that delivers an up-to-the-minute assessment of the state of proteomics and its applications in drug and biomarker discovery. The report provides insight into:

  • Strengths and weaknesses of the leading technologies for protein separation, detection, and quantification - with an emphasis on high-throughput approaches
  • The fundamental challenge posed by the vast dynamic range among protein concentrations, and the potential solutions in development and entering the market
  • Recent applications of proteomics to discover biomarkers for preeclampsia, and for neonatal ureteropelvic junction, and to differentiate between diagnosis of ALS and Parkinson' s disease
  • Technologies such as mass spectrometry, antibody-bearing chips, and solution array multiplexing to address the challenge of detecting low-abundance proteins
  • The most significant research initiatives and recent product introductions, company profiles, and the major deals and M&As that are shaping the proteomics landscape

Table of Contents

SECTION 1

  • Introduction: The Current State of Proteomics Technology

SECTION 2

  • A Brief History of Proteomics Technology

SECTION 3

  • General Overview of Proteomics Research Challenges

SECTION 4

  • Current Technologies
    • Protein Separation/Sample Enrichment
    • Liquid Chromatography
    • Protein Removal
    • Mass-coded Labeling

SECTION 5

  • Research Comparing Quantification Methods
    • Protein Identification and Quantification
    • Mass Spectrometry
    • Common MS Instrument Types
    • Antibody/Protein Array Applications
    • Protein Indentification and Quantification, Antibodies
    • Protein-Protein Interaction

SECTION 6

  • Technical Challenges
    • Dynamic Range
    • Albumin Removal

SECTION 7

  • Selected Research Methods Reports
    • Protein microarrays
    • Sample Complexity
    • Multiphoton Detection

SECTION 8

  • Selected Product Introductions
    • Beckman-Coulter
    • Sigma-Aldrich
    • Cambrex
    • Serva Electrophoresis
    • PerkinElmer
    • Thermo Electron
    • Sigma-Aldrich
    • Agilent Technologies
    • Bruker Daltonics
    • KREATECH
    • Axela Biosensors
    • Syngene
    • Sigma-Aldrich

SECTION 9

  • Selected Deals and Mergers
    • Combi Matrix/Biodesign Institute
    • Caprion/ICOS
    • Affibody/Agilent
    • PerkinElmer/Agilix
    • Applied Biosystems/Invitrogen
    • PerkinElmer/Luminex

SECTION 10

  • Expert Interviews: Current State and Future Directions
    • Roger Brent, PhD
    • Gilbert S. Omenn, MD, PhD
    • James R. Heath, PhD

SECTION 11

  • Selected Company Profiles
    • BiaCore
    • BioRad
    • Invitrogen
    • Luminex
    • Thermo Electron

APPENDIX

  • CHA Advances - 2006 Proteomics Survey

References
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