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R&D Update: What's on the Horizon for the Panic Disorder Market?

¸®¼­Ä¡»ç Decision Resources, Inc.
¹ßÇàÀÏ 2008³â 07¿ù »óǰÄÚµå 71159
ÆäÀÌÁö Á¤º¸ 21 Pages
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US $ 2,250 £Ü 2,680,800 PDF by E-mail (Global License)


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Abstract

Introduction

Panic disorder (PD) affects a large number of people and has a large diagnosed and drug-treated population. Nonetheless, the pipeline for agents to treat PD remains small, eclipsed by the development of agents for other anxiety disorders. This dearth opens a clear opportunity for an emerging agent that can offer superior effi cacy over the available options.

Get the Answers You Need to Shape Your Strategy

  • PD can be highly debilitating, with the associated anxiety causing those with this d ? isease to signifi cantly limit their activities. How many people in the seven major markets we cover (the United States, France, Germany, Italy, Spain, the United Kingdom, and Japan) have PD? What brain structures and neurotransmitters have been implicated in the development of PD? How is the disease diagnosed?
  • A variety of drug classes are used to treat PD. What are the most popular therapies for the treatment of PD? Does approval for the treatment of the disease increase the likelihood it will be prescribed?
  • Few agents are being developed for the treatment of PD. Why are drug developers choosing to develop agents for anxiety orders other than PD? What agents are currently in the pipeline for PD, and are they likely to replace any existing agents? What changes can be expected in the PD market over the next five years?

Scope

  • Overview of PD: disease description, diagnosis, pathophysiology, and prevalence.
  • Current therapies: selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and benzodiazepines.
  • Emerging therapies: challenges to developing agents for PD, Sepracor' s SEP-225441, and Alexza Pharmaceuticals' AZ-002.
  • PD market: 2007 statistics, outlook for emerging agents.

Table of Contents

  • Executive Summary
    • Strategic Considerations
    • Stakeholder Implications
  • Introduction
  • Overview of Panic Disorder
    • Disease Description
    • Diagnosis
    • Pathophysiology of Panic Disorder
      • Norepinephrine
      • Serotonin
      • Gamma-Aminobutyric Acid
      • Glutamate
      • Corticotropin-Releasing Factor
      • Substance P
    • Prevalence of Panic Disorder
  • Current Therapies for Panic Disorder
    • Selective Serotonin Reuptake Inhibitors
    • Serotonin and Norepinephrine Reuptake Inhibitors
    • Benzodiazepines
  • Emerging Therapies for Panic Disorder
    • Sepracor' s SEP-225441
    • Alexza Pharmaceuticals' AZ-002
  • Panic Disorder Market: 2007 Statistics and Future Outlook

Tables

  • 1. Characteristics of a Panic Attack
  • 2. Risk Factors for Panic Disorder
  • 3. Therapies Commonly Used to Treat Panic Disorder, 2008
  • 4. Agents in Development to Treat Anxiety Disorders, 2008
  • 5. Sales of Agents to Treat Panic Disorder, 2007

Figures

  • 1. Structures of the Brain Implicated in Panic Disorder
  • 2. Prevalent Cases of Panic Disorder in the Major Markets, 2007 and 2012
  • 3. Market Share of Drug Classes Used to Treat Panic Disorder, 2007
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