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Innovations in Medical Imaging: Technological advances, growth opportunities and future market outlook
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Business Insights |
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2009³â 08¿ù |
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99539 |
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152 pages |
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Abstract
Introduction
Medical imaging technologies are widely used in clinical diagnosis to guide
therapeutic and surgical intervention and to monitor disease progression,
recurrence and treatment response and to improve surgical navigation. A
plethora of imaging modalities are available to the medical community to
provide anatomical and functional information. Extensive research indicates
that the application of medical imaging may lead to significant reduction in
healthcare costs by increasing the speed of diagnosis, avoiding the need for
expensive treatments and surgical procedures and reducing mortality rate
through early screening programs
During the last few years there have been a number of dramatic changes within
the medical imaging as companies face tough economic and the initiation and
implementation of new legislation. The emerging markets provide strategic
opportunities for sustainable growth as patient demographics change, economies
grow and healthcare coverage expands to increase the purchasing power of the
individual.
Meanwhile reimbursement and regulation remain the two major stumbling blocks
in the development of innovative medical imaging agents, which are currently
subjected to “drug-like” criteria and rigorous standard operating
procedures. However a better reward system that pays for getting the best
patient results will ensure the right technologies are applied to get the
right answer and outcome.
Use this report to
- Highlights some of the key technologies which healthcare companies are
developing to maximize the using of medical imaging in the detection,
diagnosis and treatment of diseases
- Analyses the recent technological breakthroughs that have impacted the
medical imaging field and how this expand the use of imaging now and in the
future.
- Discusses the potential of new technologies to improve the quality of
imaging and how it may be applied in the diagnosis of a variety of diseases
- Identifies the most novel technologies that may revolutionize medical
imaging, including the use of molecular imaging and virtual surgery
- Provides recent examples of new imaging agents, equipment and software
programs and companies competing in each space.
- Analyzes the leading healthcare companies, their business strategies,
market positioning and product portfolios and discuss geographical and
technological trends now and in the future of medical imaging.
- Summarizes the challenges and opportunities that face the healthcare
industry with a focus on the implementation of new technologies and the
additional challenges associated with their use
Key findings from this report
- Diagnostic screening using imaging technologies can lead to the early
detection of disease to minimize the use of invasive procedures, enhance the
use of targeted therapies and palliative care, and improve patient management.
- New technologies that replace the need for X-rays and radioactivity are
under development such as magnetic particle imaging (MPI) could revolutionize
the way medical imaging modalities are used in the future for diagnosis,
treatment and maintenance therapy.
- Advances in medical imaging software, molecular imaging and new imaging
agents will expand the use of medical imaging in a broad range of disease and
medical settings to ensure patients receive the right technology to get the
right treatment.
- In the field of cardiology medical imaging has rapidly progressed e.g.
detect heart attacks and measure plaque build in coronary arteries. Cancer
will become the next frontier for medical imaging, where early detection can
save lives. Whilst in the future the CNS arena e.g. Alzheimer' s disease and
depression, will represent key challenges for future diagnostics.
- In addition to technological challenges face by healthcare companies the
industry faces three external challenges global economics, reimbursement and
regulation which will impact the future growth and innovation of the sector
and determine the role medical imaging will play in the future of diagnostics.
Table of Contents
Executive Summary
- Introduction
- Current issues in medical imaging & recent breakthroughs
- Challenges, opportunities & regulations
- Market, trends & future directions
Chapter 1 - Introduction
- What does medical imaging encompass?
- Anatomical & functional imaging
- Why is medical imaging of value to the pharmaceutical industry?
- Applications of medical imaging in drug R&D
- Leading imaging modalities
- X-Ray
- Computed tomography
- Magnetic resonance imaging
- Optical near-infrared fluorescence imaging
- Ultrasound
- Nuclear medicine
- Positron Emission Tomography
- Single Photon Emission Computed Tomography
- Other imaging modalities
- Comparison of imaging modalities: in vivo & ex vivo applications
- Advantages & disadvantages of imaging modalities
- Therapeutic applications
- Cancer
- Breast cancer
- Colorectal cancer
- Cardiovascular disease
- Coronary artery disease
- Stroke
- Other cardiovascular conditions
- Gastrointestinal conditions
- Orthopedics & osteoporosis
- CNS and thoracic trauma
- Therapeutic conclusions
Chapter 2 - Current issues in medical imaging & recent breakthroughs
- Pre-processing & post-processing issues
- Artifacts
- Noise
- Noise & artifact reduction
- Raw data acquisition & image reconstruction
- Image enhancement & portioning
- Conclusions on imaging issues
- Breakthroughs in medical imaging
- Novel imaging agents
- CT imaging agents
- MRI imaging agents
- Ultrasound imaging agents
- PET & SPECT imaging agents
- Imaging agent conclusions
- Novel scintillator & detectors
- Multimodality imaging devices
- SPECT-CT & PET-CT hybrids
- Spectral CT
- High field MRI
- Conclusions on imaging breakthroughs
Chapter 3 - Challenges, opportunities & regulations
- Geographical challenges & opportunities
- US market growth & legislative impact
- International markets and changing dynamics
- Urbanization and rise of the emerging markets
- Patient demographics: therapeutic dynamics
- Technical Challenges & Opportunities
- Molecular imaging
- Molecular imaging probes
- Regulatory support
- Molecular imaging consortia
- Imaging task forces
- Targeted and multifunctional imaging agents
- Nanotechnology
- Nano-enabled delivery
- Nano imaging materials
- Targeted contrast agents
- Multifunctional imaging agents
- Novel imaging modalities
- Magnetic Particle Imaging
- PET-MRI
- Real-time whole animal imaging
- Multi-spectral opto-acoustic tomography
- Computer assisted imaging & virtual surgery
- Virtual surgery
- Breakthrough conclusions
- Reimbursement & regulations
- Overall conclusions
Chapter 4 - Market trends & future directions
- The medical imaging market
- Leading manufacturers of medical imaging equipment
- Leading healthcare companies
- GE Healthcare, New York, US
- Hitachi Medical Corporation, Tokyo, Japan
- Philips Medical Systems, Amsterdam, The Netherlands
- Siemens Medical Solutions, Berlin & Munich, Germany
- Toshiba Medical Systems Corporation, Tokyo, Japan
- Recent market trends
- Global trends in medical imaging
- Technological trends in imaging equipment
- Imaging agents & nanotechnology
- Image-guided radiation therapy and patient selection
- Future directions
- Molecular imaging & diagnostics
- Medical imaging informatics and networking
- Medical imaging and virtual reality
- Summary & overall conclusions
Chapter 5 - Appendices
- Primary research methodology
- Companies involved in medical imaging
- Glossary
- Acknowledgements
- Index
- Bibliography & Endnotes
List of Figures
- Figure 1.1: Medical imaging uses a spectrum of wavelengths
- Figure 1.2: Medical imaging technologies
- Figure 1.3: Imaging techniques and their uses
- Figure 1.4: Medical imaging in the drug discovery & development process
- Figure 1.5: X-ray of a skull a) anterior-posterior and b) lateral view
- Figure 1.6: Computed tomography of the head a) coronal section and b)
sagittal section
- Figure 1.7: X-ray imagers
- Figure 1.8: Evolution of CT imaging
- Figure 1.9: Magnetic resonance imaging of the head
- Figure 1.10: Functional magnetic resonance imaging of the brain
- Figure 1.11: Multispectral imaging of the arm (700-900 nm range)
- Figure 1.12: Ultrasound image of a baby in-utero
- Figure 1.13: Principles of PET imaging
- Figure 1.14: Fused PET/CT image of anatomy and function
- Figure 1.15: SPECT detection
- Figure 1.16: video imaging
- Figure 1.17: Therapeutic application of medical imaging
- Figure 1.18: Therapeutic applications of medical imaging
- Figure 2.19: Medical imaging workflow
- Figure 2.20: CT imaging artifacts
- Figure 2.21: US imaging artifacts
- Figure 2.22: US imaging artifacts
- Figure 2.23: Recent technological breakthroughs in medical imaging
- Figure 2.24: New scintillator materials
- Figure 2.25: Opportunities in PET & SPECT for better energy resolution
- Figure 2.26: Advances collimators focus and maximize SPECT-CT
- Figure 2.27: Schematic of Spectral CT technology
- Figure 2.28: Diffusion MRI - CNS
- Figure 3.29: Historical and future outlook of MR/CT revenues in the US
(1997-2011)
- Figure 3.30: Global Population (2008)
- Figure 3.31: Population over 60: world and developed regions (1950-2050)
- Figure 3.32: Projected global deaths for selected conditions (2005-2030)
- Figure 3.33: Application of molecular imaging
- Figure 3.34: Delivery platforms for contrast agent
- Figure 3.35: Multifunctional agents
- Figure 3.36: Schematic of MPI technology
- Figure 3.37: IVIS Kinetic images in small animal models
- Figure 3.38: Real-time whole body optical imaging of Zebrafish
List of Tables
- Table 1.1: Examples of image-related biomarkers with application in a
variety of disease areas
- Table 1.2: Common PET positron-emitting tracer isotopes
- Table 1.3: Common SPECT radionuclides
- Table 1.4: Ex vivo imaging modalities
- Table 1.5: In vivo imaging modalities
- Table 1.6: Advantages & disadvantages of imaging modalities
- Table 3.7: Impact of American Recovery & Reinvestment Act (ARRA) on
healthcare & medical imaging
- Table 3.8: Recent impact of investment & regulation on international
healthcare & medical imaging markets
- Table 3.9: Typical effective radiation doses for medical imaging procedures
- Table 3.10: Leading manufacturers of small animal imaging equipment and
probes
- Table 4.11: The medical imaging market - market leaders
- Table 4.12: Leading manufacturers of medical imaging equipment
- Table 4.3: Leading manufacturers of medical imaging equipment (cont)
- Table 4.4: Recent M&A activity in the medical imaging field
- Table 4.5: Recent M&A activity in the medical imaging field (continued)
- Table 5.16: The medical imaging market - leading companies in the US
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