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Advances in Signal Transduction based Drug Discovery

¸®¼­Ä¡»ç Technical Insights, Inc.
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US $ 6,000 £Ü 7,143,000 Web Access (Regional License)
US $ 6,500 £Ü 7,738,200 Hard Copy & Web Access (Regional License)


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Abstract

This research service outlines the key global developments in the field of signal transduction.

Table of Contents

1 EXECUTIVE SUMMARY

  • Scope and Methodology
    • Scope and Segmentation of the Research Service
    • Research Methodology
  • Role of Signal Transduction in Drug Discovery
    • Drug Discovery--The Changing Paradigm
    • Industry Scenario in Signal Transduction
    • Signal Transduction-Based Drug Discovery--Technology

2 TECHNICAL DEVELOPMENTS

  • Technology Primer
    • Major Families of Signal Transducing Molecules
    • Rationale of Pathway Maps in Drug Discovery
    • Cell-Based Assay Approach to Drug Discovery
  • Assessment of Enabling Technologies - Informatics or Cell-Based Approach
    • An Informatics-Based Discovery Engine for GPCRs--Israel
    • Distinct Activated Checkpoint Therapy Platform For Drug Discovery--USA
    • Biological Illustration and Biopathway Modeling Software Tool--Japan
    • SureFire Technology Assists in Cell-Based Screening--USA
    • Functional Protein Arrays Assist in Detecting Kinases--UK
    • Nanoprobes Can Identify Cells in Action--USA
    • Platform to Assist in Protein Kinase Analysis--USA
    • Biosensor Dye to Study Signaling in Live Cells--USA
    • Pathway Analysis Tool to Assist in Drug Discovery--India
    • Cell-Based Screening Assisted with a Flexible Tag--USA
    • Proteomics Platform to Discover Protein Phosphorylation--USA
    • Signal Transduction Protein Array--First of its Kind--USA
    • A High-Throughput Ion Channel Screening Service--UK
    • Cell-Based Technology Hastens Drug Discovery Process--USA
    • A GPCR Internalization Assay--Denmark

3 TECHNOLOGY ADOPTION FACTOR ANALYSIS

  • Competitive Landscape
    • Drivers
    • Challenges
  • Industry Insights
    • Analysis of the Druggable Genome And Explorable Targets
    • Stakeholder Analysis
    • Geographic Trend Analysis

4 PATENTS AND DATABASE OF KEY INDUSTRY PARTICIPANTS

  • Patents
    • Kinase Patents
    • G-protein Coupled Receptor Patents
    • Ion-channel Receptor Patents
    • Patent Analysis
  • Key Industry Participants; Glossary
    • Key Participants
    • Glossary of Signaling Molecules

5 DECISION SUPPORT DATABASE

  • Database Tables
    • Global R&D Expenditure for Biotechnology (2002-2012)
    • Percent Government R&D Investment in Biotechnology (2002-2012)
    • Global Pharmaceutical R&D Expenditure (2002-2012)
    • Global Percentage Pharmaceutical R&D Expenditure (2002-2012)
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