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세계의 크라베병 치료 시장(2022-2029년)

Global Krabbe Disease Treatment Market - 2022-2029

리서치사 DataM Intelligence
발행일 2022년 06월 상품코드 1082813
페이지 정보 영문 180 Pages 배송안내 1-2일 (영업일 기준)
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세계의 크라베병 치료 시장(2022-2029년) Global Krabbe Disease Treatment Market - 2022-2029
발행일 : 2022년 06월 페이지 정보 : 영문 180 Pages

본 상품은 영문 자료로 한글과 영문 목차에 불일치하는 내용이 있을 경우 영문을 우선합니다. 정확한 검토를 위해 영문목차를 참고해주시기 바랍니다.

세계의 크라베병 치료에 대해 조사분석했으며, 시장의 개요와 시장 동향, 시장 촉진·억제요인, COVID-19의 영향, 업계 분석, 부문별·지역별 시장 분석, 경쟁 구도, 기업 개요 등의 정보를 정리하여 전해드립니다.

목차

제1장 세계의 크라베병 치료 시장 : 범위와 조사 방법

  • 조사 방법
  • 조사의 목적과 조사 범위

제2장 세계의 크라베병 치료 시장 : 시장의 정의와 개요

제3장 세계의 크라베병 치료 시장 : 개요

  • 질병 유형별 시장 내역
  • 진단별 시장 내역
  • 치료별 시장 내역
  • 최종사용자별 시장 내역
  • 유통 채널별 시장 내역
  • 지역별 시장 내역

제4장 세계의 크라베병 치료 시장 역학

  • 시장에 영향을 미치는 요인
    • 촉진요인
    • 억제요인 :
    • 시장 기회
    • 영향 분석

제5장 세계의 크라베병 치료 시장 : 업계 분석

  • 공급망 분석
  • 가격 분석
  • 미충족 요구

제6장 세계의 크라베병 치료 시장 : COVID-19 분석

  • 시장에 대한 COVID-19의 영향 분석
    • COVID-19 이전 시장 시나리오
    • 현재의 COVID-19 시장 시나리오
    • COVID-19 이후 또는 향후 시나리오
  • COVID-19 중 가격변동
  • 수요와 공급 스펙트럼
  • 팬데믹시 시장에 관련된 정부 구상
  • 제조업체의 전략적 구상
  • 결론

제7장 세계의 크라베병 치료 시장 : 질병 유형별

  • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 질병 유형별
    • 시장 매력 지수 : 질병 유형별
  • 유아성
    • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
  • 지발성

제8장 세계의 크라베병 치료 시장 : 진단별

  • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 매력 지수 : 진단별
  • 임상 검사
    • 혈액검사
    • 기타
    • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
  • 영상 검사
    • 자기공명영상법(MRI)
    • 컴퓨터단층촬영(CT)
    • 기타
  • 유전자 검사
  • 신생아 스크리닝
  • 기타

제9장 세계의 크라베병 치료 시장 : 치료별

  • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 매력 지수 : 치료별
  • 항경련약
    • Acetazolamide
    • Carbamazepine
    • Tegretol
    • Clobazam
    • Gabapentin
    • 기타
    • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
  • 근이완약
    • Tizanidine
    • Carisoprodol
    • Chlorzoxazone
    • Metaxalone
    • 기타
  • 골수 이식
  • 줄기세포 이식
  • 기타

제10장 세계의 크라베병 치료 시장 : 최종사용자별

  • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 매력 지수 : 최종사용자별
  • 병원
    • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
  • 진단 센터
  • 클리닉
  • 기타

제11장 세계의 크라베병 치료 시장 : 유통 채널별

  • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별
    • 시장 매력 지수 : 유통 채널별
  • 병원 약국
    • 서론
    • 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
  • 소매 약국
  • 온라인 약국
  • 기타

제12장 세계의 크라베병 치료 시장 : 지역별

  • 서론
    • 지역별 시장 규모 분석·전년대비 성장 분석(%) : 2020-2029년 및 2021-2029년(백만 달러)
    • 지역별 시장 매력 지수
  • 북미
    • 서론
    • 주요 지역 고유 역학
    • 시장 규모 분석·전년대비 성장 분석(%) : 질환 유형별
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별
    • 시장 규모 분석·전년대비 성장 분석(%) : 국가별
  • 유럽
    • 서론
    • 주요 지역 고유 역학
    • 시장 규모 분석·전년대비 성장 분석(%) : 질환 유형별
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별
    • 시장 규모 분석·전년대비 성장 분석(%) : 국가별
  • 남미
    • 서론
    • 주요 지역 고유 역학
    • 시장 규모 분석·전년대비 성장 분석(%) : 질환 유형별
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별
    • 시장 규모 분석·전년대비 성장 분석(%) : 국가별
  • 아시아태평양
    • 서론
    • 주요 지역 고유 역학
    • 시장 규모 분석·전년대비 성장 분석(%) : 질환 유형별
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별
    • 시장 규모 분석·전년대비 성장 분석(%) : 국가별
  • 중동과 아프리카
    • 서론
    • 주요 지역 고유 역학
    • 시장 규모 분석·전년대비 성장 분석(%) : 질환 유형별
    • 시장 규모 분석·전년대비 성장 분석(%) : 진단별
    • 시장 규모 분석·전년대비 성장 분석(%) : 치료별
    • 시장 규모 분석·전년대비 성장 분석(%) : 최종사용자별
    • 시장 규모 분석·전년대비 성장 분석(%) : 유통 채널별

제13장 경쟁 구도

  • 주요 발전과 전략
  • 기업 점유율 분석
  • 제품 벤치마킹
  • 주목할 만한 주요 기업의 리스트

제14장 기업 개요

  • Lannett
    • 기업 개요
    • 제품 포트폴리오·설명
    • 주요 하이라이트
    • 재무 개요
  • Novartis
  • Lundbeck
  • Lupin Pharmaceuticals, Inc.
  • Teva Pharmaceuticals USA, Inc.
  • Meda Pharmaceuticals Inc
  • Mayne Pharma Group Limited
  • Pfizer Inc.
  • Schwarz Pharma, Inc
  • Acorda Therapeutics Inc.

제15장 세계의 크라베병 치료 시장 : DataM

KSA 22.06.21

Market Overview

The global krabbe disease treatment market size was valued US$ XX million in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of XX % during the forecast period (2022-2029).

Krabbe disease is a life-threatening neurological disorder commonly known as globoid cell leukodystrophy. It is one of a series of conditions known as leukodystrophies, caused by the breakdown of myelin in the nervous system (demyelination). Myelin is the protective layer that surrounds nerve cells and ensures that nerve signals are transmitted quickly. Krabbe illness is also characterized by aberrant brain cells known as globoid cells, huge cells with more than one nucleus. Krabbe disease is identified in children as young as six years old, and there is presently no cure; nevertheless, the condition is controlled by supportive care.

Market Dynamics

Advancement in the therapies for the treatment of Krabbe Disease is expected to drive market growth.

Other experimental medicines have demonstrated varying degrees of effectiveness in preclinical testing, with some of the best results from combining medications. For instance, HSCT has been used with SRT and gene therapy. The combinations consistently yield better outcomes than the matched individual therapies. Other approaches such as ERT, chaperone therapy, and anti-inflammatory therapy also have the potential to contribute as part of a combination or standalone therapies. Moreover, various clinical studies have been carried out. For instance, D-Cycloserine is an FDA-approved medicine for tuberculosis tested in numerous clinical studies for various diseases. Preliminary data suggest that it can slow disease progression in twitcher mice; consequently, D-cycloserine should be studied further to see if it can help individuals with Krabbe disease. Thus, the market is expected to drive in the forecast period from the above statements.

Restraint:

The finite patient pool for clinical trials, lack of awareness of the disease and side effects of the drugs are factors the market is expected to hamper in the forecast period.

COVID-19 Impact Analysis

The COVID-19 pandemic has moderately impacted healthcare systems and the market. The risk of severe forms of COVID-19 may be high in the rare metabolic community, where all patients, including children, experience multiorgan impairments due to their chronic condition. MetabERN, the European Reference Network for Hereditary Metabolic Diseases, conducted two surveys: one for patients' organizations (PO) and the other for healthcare providers (HCPs). COVID-19 incidence was lower in the community of uncommon metabolic patients (72.9 per 100,000 vs. 117 per 100,000) than in the general European population. On the other hand, patients were subjected to significant disruptions in their care, with most appointments and treatments being canceled, curtailed, or postponed. Almost all HCPs (90 percent) used telemedicine to replace face-to-face visits, about half of patients undergoing treatment changes switched from hospital to home therapy, and a quarter of patients had difficulty getting their medications.

Additionally, the pandemic interrupts the supply chain and process. Many companies will vary to other geographic regions to ensure that products remain available and protect their supply chain. Thus, from the above statements, the market got affected, and it is expected to gain traction quickly with the resumption of the economic activities.

Segment Analysis

Stem cell transplantation segment is expected to hold the largest market share in krabbe disease treatment market

The stem cell transplantation segment is expected to dominate in 2021. The segment benefits because if treatment begins before the development of symptoms, that is, when a diagnosis is made via a newborn screening test, this therapy may improve outcomes in newborns. According to current evidence, stem cell transplantation is most beneficial when initiated before a newborn reaches the age of two weeks. Moreover, Pre-symptomatic children who have stem cell transplantation had a slower disease progression and a better quality - and duration - of life than children who do not receive stem cell transplantation before symptoms arise, according to studies. Furthermore, This medication may also benefit older children and adults with modest Krabbe disease symptoms. Thus, the market segment is expected to hold the largest market share in the forecast period from the above statements.

Geographical Analysis

North America region holds the largest market share in the global krabbe disease treatment market

In 2021, North America accounted for the highest revenue share. The increasing prevalence of Krabbe Disease, rising geriatric population, Rapid adoption of cutting-edge technologies and novel medications for the treatment of Krabbe illness, well-established infrastructure and increase in clinical development of the treatment for the Krabbe disease, and rise in investment in research & development are some of the factors the market is expected to boost in the forecast period. For instance, the Krabbe disease affects about 1 in 100,000 people in the United States. It is also known as globoid cell leukodystrophy. Males are affected as often as females.

Also, more than two-fifths of all known cases of Krabbe disease is caused by a missense mutation in the GLC enzyme. Therapeutic approaches for other lysosomal storage diseases are ineffective in treating Krabbe disease due to the lack of accumulated primary substrate within the lysosome and the predominant CNS sickness. The molecules are being researched because they have the potential to pass the blood-brain barrier more efficiently than enzymes due to certain properties such as low molecular weight, low toxicity, and high bioavailability. Allosteric chaperones, directed away from the enzyme's active site, have also been found. Pharmacological chaperone therapy, which is expected to be effective, can be used to treat Krabbe disease. Thus, the North American region is expected to hold the largest market share in the forecast period from the above statements.

Competitive Landscape

Major key players in the krabbe disease treatment market are Lannett, Novartis, Lundbeck, Lupin Pharmaceuticals, Inc., Teva Pharmaceuticals USA, Inc., Meda Pharmaceuticals Inc , Mayne Pharma Group Limited, Pfizer Inc., Schwarz Pharma, Inc, Acorda Therapeutics Inc.

Pfizer Inc.:

Overview:

Pfizer Inc. is an American multinational pharmaceutical company that offers medicines, vaccines, medical devices, and consumer healthcare products for oncology, inflammation, cardiovascular, and other therapeutic areas. It has a portfolio of over 150 products across 15 therapeutic areas. The company develops and produces medicines and vaccines for a wide range of medical disciplines, including immunology, oncology, cardiology, endocrinology, and neurology.

­Product Portfolio:

SKELAXIN(metaxalone): Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain. It is used with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

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Target Audience

Service Providers/ Buyers

Industry Investors/Investment Bankers

Education & Research Institutes

Research Professionals

Emerging Companies

Manufacturers

Table of Contents

1. Methodology and Scope

  • 1.1. Research Methodology
  • 1.2. Research Objective and Scope of the Report

2. Market Definition and Overview

3. Executive Summary

  • 3.1. Market Snippet by Disease Type
  • 3.2. Market Snippet by Diagnosis
  • 3.3. Market Snippet by Treatment
  • 3.4. Market Snippet by End user
  • 3.5. Market Snippet by Distribution channel
  • 3.6. Market Snippet by Region

4. Market Dynamics

  • 4.1. Market Impacting Factors
    • 4.1.1. Drivers
      • 4.1.1.1. Advancement in the therapies for the treatment of Krabbe Disease is expected to drive market growth.
    • 4.1.2. Restraints:
      • 4.1.2.1. Lack of awareness of the disease and side effects of the drugs are factors the market is expected to hamper in the forecast period.
    • 4.1.3. Opportunity
    • 4.1.4. Impact Analysis

5. Industry Analysis

  • 5.1. Supply Chain Analysis
  • 5.2. Pricing Analysis
  • 5.3. Unmet Needs

6. COVID-19 Analysis

  • 6.1. Analysis of Covid-19 on the Market
    • 6.1.1. Before COVID-19 Market Scenario
    • 6.1.2. Present COVID-19 Market Scenario
    • 6.1.3. After COVID-19 or Future Scenario
  • 6.2. Pricing Dynamics Amid Covid-19
  • 6.3. Demand-Supply Spectrum
  • 6.4. Government Initiatives Related to the Market During Pandemic
  • 6.5. Manufacturers Strategic Initiatives
  • 6.6. Conclusion

7. By Disease Type

  • 7.1. Introduction
    • 7.1.1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 7.1.2. Market Attractiveness Index, By Disease Type Segment
  • 7.2. Infantile*
    • 7.2.1. Introduction
    • 7.2.2. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
  • 7.3. Late-onset

8. By Diagnosis

  • 8.1. Introduction
    • 8.1.1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 8.1.2. Market Attractiveness Index, By Diagnosis Segment
  • 8.2. Laboratory tests*
    • 8.2.1. Blood Test
    • 8.2.2. Others
    • 8.2.3. Introduction
    • 8.2.4. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
  • 8.3. Imaging tests
    • 8.3.1. Magnetic resonance imaging (MRI)
    • 8.3.2. Computerized tomography (CT)
    • 8.3.3. Others
  • 8.4. Genetic testing
  • 8.5. Newborn screening
  • 8.6. Others

9. By Treatment

  • 9.1. Introduction
    • 9.1.1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 9.1.2. Market Attractiveness Index, By Treatment Segment
  • 9.2. Anticonvulsant Agents*
    • 9.2.1. Acetazolamide
    • 9.2.2. Carbamazepine
    • 9.2.3. Tegretol
    • 9.2.4. Clobazam
    • 9.2.5. Gabapentin
    • 9.2.6. Others
    • 9.2.7. Introduction
    • 9.2.8. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
  • 9.3. Muscle Relaxer Drugs
    • 9.3.1. Tizanidine
    • 9.3.2. Carisoprodol
    • 9.3.3. Chlorzoxazone
    • 9.3.4. Metaxalone
    • 9.3.5. Others
  • 9.4. Bone Marrow Transplantation
  • 9.5. Stem cell transplantation
  • 9.6. Others

10. By End user

  • 10.1. Introduction
    • 10.1.1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 10.1.2. Market Attractiveness Index, By End user Segment
  • 10.2. Hospitals*
    • 10.2.1. Introduction
    • 10.2.2. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
  • 10.3. Diagnostic Centers
  • 10.4. Clinics
  • 10.5. Others

11. By Distribution Channel

  • 11.1. Introduction
    • 11.1.1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    • 11.1.2. Market Attractiveness Index, By Distribution Channel Segment
  • 11.2. Hospital Pharmacies*
    • 11.2.1. Introduction
    • 11.2.2. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
  • 11.3. Retail Pharmacies
  • 11.4. Online Pharmacies
  • 11.5. Others

12. By Region

  • 12.1. Introduction
    • 12.1.1. Market Size Analysis, US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029, By Region
    • 12.1.2. Market Attractiveness Index, By Region
  • 12.2. North America
    • 12.2.1. Introduction
    • 12.2.2. Key Region-Specific Dynamics
    • 12.2.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 12.2.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 12.2.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 12.2.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 12.2.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    • 12.2.8. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 12.2.8.1. U.S.
      • 12.2.8.2. Canada
      • 12.2.8.3. Mexico
  • 12.3. Europe
    • 12.3.1. Introduction
    • 12.3.2. Key Region-Specific Dynamics
    • 12.3.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 12.3.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 12.3.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 12.3.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 12.3.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    • 12.3.8. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 12.3.8.1. Germany
      • 12.3.8.2. U.K.
      • 12.3.8.3. France
      • 12.3.8.4. Italy
      • 12.3.8.5. Spain
      • 12.3.8.6. Rest of Europe
  • 12.4. South America
    • 12.4.1. Introduction
    • 12.4.2. Key Region-Specific Dynamics
    • 12.4.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 12.4.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 12.4.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 12.4.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 12.4.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    • 12.4.8. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 12.4.8.1. Brazil
      • 12.4.8.2. Argentina
      • 12.4.8.3. Rest of South America
  • 12.5. Asia Pacific
    • 12.5.1. Introduction
    • 12.5.2. Key Region-Specific Dynamics
    • 12.5.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 12.5.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 12.5.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 12.5.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 12.5.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    • 12.5.8. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 12.5.8.1. China
      • 12.5.8.2. India
      • 12.5.8.3. Japan
      • 12.5.8.4. Australia
      • 12.5.8.5. Rest of Asia Pacific
  • 12.6. Middle East and Africa
    • 12.6.1. Introduction
    • 12.6.2. Key Region-Specific Dynamics
    • 12.6.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Disease Type
    • 12.6.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Diagnosis
    • 12.6.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Treatment
    • 12.6.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End user
    • 12.6.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel

13. Competitive Landscape

  • 13.1. Key Developments and Strategies
  • 13.2. Company Share Analysis
  • 13.3. Product Benchmarking
  • 13.4. List of Key Companies to Watch

14. Company Profiles

  • 14.1. Lannett*
    • 14.1.1. Company Overview
    • 14.1.2. Product Portfolio and Description
    • 14.1.3. Key Highlights
    • 14.1.4. Financial Overview
  • 14.2. Novartis
  • 14.3. Lundbeck
  • 14.4. Lupin Pharmaceuticals, Inc.
  • 14.5. Teva Pharmaceuticals USA, Inc.
  • 14.6. Meda Pharmaceuticals Inc
  • 14.7. Mayne Pharma Group Limited
  • 14.8. Pfizer Inc.
  • 14.9. Schwarz Pharma, Inc
  • 14.10. Acorda Therapeutics Inc.

LIST NOT EXHAUSTIVE

15. Global Krabbe Disease Treatment Market - DataM

  • 15.1. Appendix
  • 15.2. About Us and Applications
  • 15.3. Contact Us
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