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세계의 골이식 대체재 시장

Bone Graft Substitutes

리서치사 Global Industry Analysts, Inc.
발행일 2019년 05월 상품 코드 225215
페이지 정보 영문 211 Pages
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세계의 골이식 대체재 시장 Bone Graft Substitutes
발행일 : 2019년 05월 페이지 정보 : 영문 211 Pages

세계의 골이식 대체재(Bone Graft Substitutes) 시장을 조사했으며, 시장 현황과 향후 성장 예측, 지역별 동향, 시장 진출기업 개요 등의 정보를 정리하여 전해드립니다.

제1장 서론, 조사 방법, 제품 정의

제2장 업계 개요

  • 골이식편 : 서론
  • 전망
  • 도상국에 큰 수익 가능성
  • 정형외과 시술 건수 증가가 밝은 전망
  • 뼈이식 : 골절 치료의 중요한 처치
  • 의사가 뼈 의식을 결정하게 하는 요인
  • 다른 골이식재의 문제
  • 우선사항인 환자 안전성
  • 연구개발을 촉진하는 미충족 요구 등

제3장 성장 촉진요인, 과제, 동향

  • 성장 영향요인
  • 퇴행성 추간판 질환 발병률 상승
  • 관절염과 기타 정형외과 질환 유병률 상승
  • 정형외과 수술 증가
  • 민간의료에서의 척추 고정 증가 등

제4장 제품 개요

  • 골이식편 : 정의
  • 골이식편 : 작용기전
  • 골이식편의 종류
  • 골이식편의 용도 등

제5장 규제 환경

  • 규제 문제
  • 미국 식품의약국(FDA)의 분류
  • 인체세포, 조직, 세포 및 조직 유래 제품
  • 조직은행 규제
  • FDA의 규제
  • 합성 골이식 대체재 등

제6장 경쟁 환경

  • 주목 기업
    • AlloSource
    • Baxter International, Inc.
    • DePuy Synthes Companie
    • Exactech, Inc.
    • SeaSpine Holdings Corporation
    • LifeNet Health, Inc.
    • Medtronic plc
    • NovaBone Products LLC
    • NuVasive, Inc.
    • Orthofix International N V
    • RTI Surgical, Inc.
    • Smith & Nephew Plc
    • Stryker Corporation
    • Wright Medical Group N.V.
    • Xtant Medical Holdings, Inc.
    • Zimmer Biomet Holdings, Inc.
  • 제품 혁신과 도입
  • 최근의 업계 활동

제7장 세계 시장 전망

제8장 지역별 시장 동향

  • 미국
  • 캐나다
  • 일본
  • 유럽
  • 아시아태평양
  • 라틴아메리카
  • 기타 국가

제9장 기업 개요

LSH 18.07.24

이 페이지에 게재되어 있는 내용은 최신판과 약간 차이가 있을 수 있으므로 영문목차를 함께 참조하여 주시기 바랍니다. 기타 자세한 사항은 문의 바랍니다.

This report analyzes the worldwide markets for Bone Graft Substitutes in US$ Million. The US market is additionally analyzed by the following Segments: Demineralized Bone Matrix, Bone Morphogenetic Protein, Stem Cell Based Bone Grafts, and Synthetic Bone Grafts. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World. Annual estimates and forecasts are provided for the period 2016 through 2024. Also, a five-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 42 companies including many key and niche players such as -

AlloSource
Baxter International, Inc.
DePuy Synthes Companies
Exactech, Inc.
SeaSpine Holdings Corporation
LifeNet Health, Inc.

Table of Contents

1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

2. INDUSTRY OVERVIEW

  • Bone Grafts - A Prelude
  • Outlook
  • Developing Markets Hold Lucrative Potential for Bone Graft Substitutes
  • Rise in Volume of Orthopedic Procedures Boosts Prospects
    • Table 1: Global Orthopedic Surgical Procedure Volume (2010-2020) (in million) (includes corresponding Graph/Chart)
    • Table 2: Global Orthopedic Market by Segment (2017): Percentage Breakdown of Value Sales for Extremities, Hips, Knees, Orthobiologics, Spine, Trauma and Others (includes corresponding Graph/Chart)
  • Bone Grafting - An Important Procedure for Healing Fractures
    • Table 3: Fractures by Age Group (2017): Percentage Share Breakdown of Number of Fractures by Age Group (includes corresponding Graph/Chart)
  • What Drives Physicians' Choice of Bone Grafts?
  • Challenges for Different Bone Grafts
  • Patient Safety Emerges as a Top Priority
  • Unmet Clinical Needs to Foster R&D Engine
  • Advanced Allografts Encroach the Use of Autografts in Surgical Procedures
  • Rise in Popularity of Synthetic Bone Graft Substitutes
  • Bone Morphogenetic Protein - Safety Concerns Impact Growth Prospects
  • Stem Cell Based Bone Grafts: Promising Growth Ahead
  • DBM: Strong Growth but Tough Competition
  • Demineralized Bone Matrix (DBM) Allografts Offered by Select Companies

3. GROWTH DRIVERS, ISSUES & TRENDS

  • A Review of Major Factors Affecting Growth
  • Increasing Incidence of Degenerative Intervertebral Disc Diseases
    • Table 4: % of Women Affected by Osteoporosis (includes corresponding Graph/Chart)
  • Rising Prevalence of Arthritis and Other Orthopedic Disorders
  • Growing Number of Revision Orthopedic Surgeries
  • Rise in Spinal Fusions in Private Healthcare
  • Foot and Extremity Reconstruction - Promising Market for Bone Grafts
  • Spine Fusion - The Largest Application Market for Bone Graft Substitutes
  • Dental Bone Grafting - A High Potential Market
    • Table 5: Dental Implants Penetration Worldwide (2015) - Number of Dental Implants Placed Per 10,000 Persons in Select Countries (includes corresponding Graph/Chart)
  • Adoption of Dental Implants - Breakdown by Number of Implants in Select Countries
    • Table 6: Dental Tissue & Bone Regeneration Materials Market (2017): Percentage Share Breakdown by Segment for Allografts, Synthetics, and Xenografts (includes corresponding Graph/Chart)
  • Increasing Visibility of Orthobiological Products to Spur Grafting Options
  • Technological Advancements Drive Bone Grafts Market
  • A Glance at Few Recent Innovations/Research Efforts in Bone Grafts
    • Sea Coral Offers Perfect Biomaterial for Bone Grafts
    • Indian Scientists at Synthera Develop Innovative Bone Graft Substitutes
    • NJIT Receives Grant to Commercialize New Bone Graft Substitute Technology
    • Consortium to Develop SmartBonePep(r) Bio-hybrid Composite Bone Graft
    • QMUL Researchers Develop Inductigraft Synthetic Bone Grafts
    • Researchers Develop Aerograft Dental Bone Graft Material for Dental Procedures
  • Precision Machined Allografts Gain Surgeon Preference
  • Disease Transmission through Bone Grafts - A Major Safety Concern
  • Lack of Standards in Bone Graft Substitute Market
  • Reimbursement Issues Continue to Haunt Bone Grafts Market
  • Regional Regulations & Religious Beliefs Hamper Bone Graft Substitutes Market
  • Synthetic Bone Grafts - Solution for Halal Bone Graft Implantation
  • Bone Glue - A Potential Threat to the Bone Graft Market
  • Alliances with Organ Procurement Organizations: A Shot in the Arm
  • Limited Availability of Donor Tissues
  • Competition Intensifies from Alternative Tissue Repair Therapies
  • Substitute Technologies Threaten to Replace Spinal Fusions
  • Bone Grafts Termed as Tissues Suffer From Inconsistent Patient Outcomes
  • New Ways of Fixing Broken Bones
  • BoneCure Sleeve - Heading Towards the Human Market
  • Bioactive Glass - Suitable for Weight Bearing Portion
  • Review of Demographic Drivers
  • Aging Population: A Strong Demographic Driver
    • Table 7: Global Aging Population in Select Regions/Countries: Population of 60+ Individuals in '000s and as a Percentage of Total Population for 2015 & 2050 (includes corresponding Graph/Chart)
  • Rise in Global Obesity Epidemic Boosts Market Growth
  • Facts & Statistics on the Rising Obesity Levels: Important Opportunity Indicators
    • Table 8: World Obesity Prevalence (2015 & 2022): Percentage of Obese Population for Leading Ten Countries (includes corresponding Graph/Chart)

4. PRODUCT OVERVIEW

  • Bone Grafts: A Definition
  • Bone Grafts: A Peek into their Mechanism of Action
  • Types of Bone Grafts
  • Scoring of Osteoconduction, Osteoinduction, and Osteogenesis Properties of Bone Grafts by Type
  • Autografts
  • Standard Allografts
  • Machined Bone Allografts
  • Demineralized Bone Matrix
  • Bone Morphogenetic Proteins (BMPs)
    • Basic Functions of TGF-Beta
  • Synthetic Bone Grafts
  • Collagen-based Matrices
  • Ceramic: A Material of Choice
  • Hydroxyapatite: A Major Calcium Phosphate Based Ceramic
  • Calcium Sulfate
  • Polymer Based Bone Grafts
  • Coral: A Valuable Synthetic Graft Material
  • Application of Bone Grafts
  • Spinal Fusion
  • Trauma & Reconstructive Surgeries
    • Trauma
    • Reconstructive Surgeries
      • Joint Revision Arthroplasty
      • Oral, Periodontal, and Cranio-Maxillofacial
  • Tissue Recovery & Processing: A Review
  • Tissue Banks
  • Tissue Processing
  • Tissue Distribution
    • An Illustration of the Tissue Recovering, Processing, & Distribution Network

5. REGULATORY ENVIRONMENT

  • Regulatory Issues
  • FDA Classification of Bone Products
  • Human Cells, Tissues and Cellular and Tissue-Based Products (HCT/Ps)
  • National Organ Transplant Act (NOTA)
  • Good Tissue Practices
  • Tissue Banking Regulation
  • FDA Regulations on Xenograft
  • DBM-based Products in US
  • Synthetic Bone Graft Substitutes

6. COMPETITIVE LANDSCAPE

  • Bone Graft Products of Select Players
  • 6.1 Focus on Select Players
  • AlloSource (USA)
  • Baxter International, Inc. (USA)
  • DePuy Synthes Companies (USA)
  • Exactech, Inc. (USA)
  • SeaSpine Holdings Corporation (USA)
  • LifeNet Health, Inc. (USA)
  • Medtronic plc (Ireland)
  • NovaBone Products LLC (USA)
  • NuVasive, Inc. (USA)
  • Orthofix International N V (Curacao)
  • RTI Surgical, Inc. (USA)
  • Smith & Nephew Plc (UK)
  • Stryker Corporation (USA)
  • Wright Medical Group N.V. (Netherlands)
  • Xtant Medical Holdings, Inc. (USA)
  • Zimmer Biomet Holdings, Inc. (USA)
  • 6.2 Product Innovations/Introductions
  • AlloSource and Stryker Unveil the ProChondrix(r)CR Cryopreserved Osteochondral Allograft
  • LifeNet Health launches AngioGraft(r) Aortoiliac Artery
  • Royal Biologics Launches MAXX(tm)-FuseLine of Allografts
  • NovaBone launches NovaBone IRM and IRM MacroPOR Biologically Active Bone Graft Substitutes
  • Leader Biomedical Group DBM, cleaned with eCOO(r) Clean Technology
  • Antibe Therapeutics Launches PentOS OI(tm) Max for Dental Biologics Market
  • Zimmer Biomet Introduces PrimaGen Advanced Allograft
  • Citagenix Launches PentOS OI(tm) Putty Bone Graft Substitute
  • AlloSource(r) Introduces ProChondrix(r) Cartilage Restoration Matrix
  • 6.3 Recent Industry Activity
  • Bonesupport Enters into Agreement with Collagen Matrix
  • DePuy Synthes Enters into Agreement with Prosidyan to Promote the FIBERGRAFT(r) Family of Products in the US
  • Medtronic Receives FDA Approval of Infuse(TM) Bone Graft in New Spine Surgery Indications
  • Exactech Completes Merger with TPG Capital
  • Molecular Matrix Receives FDA Clearance for Osteo-PTM Synthetic Bone Graft Substitute
  • RTI Surgical to Acquire Zyga Technology
  • SeaSpine Receives FDA 510(k) Clearance for OsteoBallast(tm) Demineralized Bone Matrix in Resorbable Mesh
  • BONESUPPORT(tm) Signs Agreement for Bio-Ceramic Bone Substitute Products in the Italian Market
  • Prosidyan Receives FDA 510(k) Clearance for FIBERGRAFT(r) BG Matrix - Bone Graft Substitute for Postero-lateral Spinal Fusion
  • DSM Enters into Partnership with Cerapedics to Develop and Manufacture Next Generation of Peptide Enhanced Bone Graft
  • Artoss Announces Availability of NanoBone Bone Graft Products through DAPA
  • Bonesupport(tm) Enters into Commercialization Agreement for the French Market
  • BoneSupport Extends Distribution agreement with Zimmer Biomet for Cerament TM Bone Void Filler
  • Kuros Biosciences Acquires Xpand Biotechnology
  • AllowSource Receives Patent for ProChondrix(r) Cartilage Restoration Matrix
  • MiMedx Group Takes Over Stability Biologics

7. GLOBAL MARKET PERSPECTIVE

    • Table 9: World Recent Past, Current and Future Analysis for Bone Graft Substitutes by Geographic Region/Country - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 10: World Historic Review for Bone Graft Substitutes by Geographic Region/ Country - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
    • Table 11: World 14-Year Perspective for Bone Graft Substitutes by Geographic Region/Country - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2011, 2018 & 2024 (includes corresponding Graph/Chart)

8. REGIONAL MARKET PERSPECTIVE

  • 8.1 The United States
  • A. Market Analysis
    • US-The Largest Market for Bone Graft Substitutes
    • Aging Population: A Weighty Demographic Growth Factor
    • Table 12: North American Elderly Population by Age Group (1975-2050) (includes corresponding Graph/Chart)
    • Table 13: US Population Breakdown by Age Group (2017) (includes corresponding Graph/Chart)
    • Rising Incidence of Degenerative Intervertebral Disc Diseases
      • Back Pain
      • Arthritis
    • Table 14: % of Population Diagnosed with Arthritis by Age Group (includes corresponding Graph/Chart)
      • Osteoporosis
    • Table 15: Breakdown of Osteoporotic Fractures by Site in the US (includes corresponding Graph/Chart)
    • Rise in Revision Orthopedic Surgeries Bodes Well for Bone Graft Substitutes Market
    • Synthetic Bone Grafts to Drive Growth
    • Stem Cell Bone Grafts: A Promising Segment in BGS Market
    • Spinal Surgery Market: Opportunity for Bone Grafts Market
    • Table 16: US Spinal Fusion Surgery Market: Percentage Breakdown of Procedure Volume by Age Group (includes corresponding Graph/Chart)
    • Dental Bone Graft Substitutes Market: An Overview
    • Table 17: Dental Implants Market in the US - Incidence of Dental Implant Procedures in '000s for the Years 2016, 2020 & 2025 (includes corresponding Graph/Chart)
    • Orthopedic Biomaterials Market - An Overview
    • Orthobiologics Market - Overview
    • Regulatory Challenges Limit Growth in the Bone Graft Substitutes
    • Competitive Scenario
    • Table 18: US Market for Bone Graft Substitutes (2017E): Percentage Market Share Breakdown of Leading Suppliers (includes corresponding Graph/Chart)
  • B. Market Analytics
    • Table 19: US Recent Past, Current and Future Analysis for Bone Graft Substitutes by Product Segment - Demineralized Bone Matrix (DBM), Bone Morphogenetic Protein (BMP), Stem Cell Based Grafts, and Synthetic Bone Grafts Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 20: US Historic Review for Bone Graft Substitutes by Product Segment - Demineralized Bone Matrix (DBM), Bone Morphogenetic Protein (BMP), Stem Cell Based Grafts, and Synthetic Bone Grafts Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
    • Table 21: US 14-Year Perspective for Bone Graft Substitutes by Product Segment - Percentage Breakdown of Revenues for Demineralized Bone Matrix (DBM), Bone Morphogenetic Protein (BMP), Stem Cell Based Grafts, and Synthetic Bone Grafts Markets for Years 2011, 2018 & 2024 (includes corresponding Graph/Chart)
  • 8.2 Canada
  • Market Analysis
    • Table 22: Canadian Recent Past, Current and Future Analysis for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 23: Canadian Historic Review for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
  • 8.3 Japan
  • A. Market Analysis
    • Current and Future Analysis
    • Dental Bone Graft Substitutes Market
  • B. Market Analytics
    • Table 24: Japanese Recent Past, Current and Future Analysis for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 25: Japanese Historic Review for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
  • 8.4 Europe
  • A. Market Analysis
    • European Market for Bone Graft Substitutes: An Overview
    • Table 26: European Bone Graft Substitutes Market (2017): Percentage Share Breakdown of Value Sales for Synthetic, Allograft, and DBM (includes corresponding Graph/Chart)
      • Synthetic Bone Graft Drives the BGS Market
      • Bone Morphogenetic Protein (BMP) Market
    • Dental Biomaterials Market in Europe: An Insight
  • B. Market Analytics
    • Table 27: European Recent Past, Current and Future Analysis for Bone Graft Substitutes by Geographic Region/Country - France, Germany, Italy, UK, Spain and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 28: European Historic Review for Bone Graft Substitutes by Geographic Region/Country - France, Germany, Italy, UK, Spain and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
    • Table 29: European 14-Year Perspective for Bone Graft Substitutes by Geographic Region/Country - Percentage Breakdown of Revenues for France, Germany, Italy, UK, Spain and Rest of Europe Markets for Years 2011, 2018 & 2024 (includes corresponding Graph/Chart)
  • 8.5 Asia-Pacific
  • A. Market Analysis
    • Current and Future Analysis
    • Dental Bone Graft Substitutes Market in Asia-Pacific - An Overview
    • Table 30: Leading Players in the Dental Bone Graft Substitutes Market in Asia-Pacific (2015E): Percentage Share Breakdown of Sales for Geistlich and Others (includes corresponding Graph/Chart)
    • Table 31: Over 65 Years Individuals as % of Total Population in Select Asian Countries (2015) (includes corresponding Graph/Chart)
    • Focus on Select Regional Markets
      • Australia
    • Table 32: Dental Bone Graft Substitutes Market in Australia (2020P): Percentage Share Breakdown of Volume Sales by Segment - Demineralized Allografts, Mineralized Allografts, Synthetic Grafts, and Xenografts (includes corresponding Graph/Chart)
      • China
      • India
      • Current and Future Analysis
      • Malaysia
      • South Korea
    • Table 33: Dental Bone Graft Substitutes Market in South Korea (2015E): Percentage Share Breakdown of Volume Sales by Material - Allograft, Synthetic Graft and Xenograft (includes corresponding Graph/Chart)
      • Singapore
  • B. Market Analytics
    • Table 34: Asia-Pacific Recent Past, Current and Future Analysis for Bone Graft Substitutes by Geographic Region/Country - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 35: Asia-Pacific Historic Review for Bone Graft Substitutes by Geographic Region/Country - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
    • Table 36: Asia-Pacific 14-Year Perspective for Bone Graft Substitutes by Geographic Region/ Country - Percentage Breakdown of Revenues for China, India and Rest of Asia-Pacific Markets for Years 2011, 2018 & 2024 (includes corresponding Graph/Chart)
  • 8.6 Latin America
  • A. Market Analysis
    • Current and Future Analysis
    • Dental Bone Graft Substitutes Market
    • Table 37: Percentage of People with Edentulous Jaws by in Brazil (2000, 2010 & 2015) (includes corresponding Graph/Chart)
    • Brazilian Orthopedic Devices Market
  • B. Market Analytics
    • Table 38: Latin American Recent Past, Current and Future Analysis for Bone Graft Substitutes by Geographic Region/Country - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 39: Latin American Historic Review for Bone Graft Substitutes by Geographic Region/ Country - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
    • Table 40: Latin American 14-Year Perspective for Bone Graft Substitutes by Geographic Region/Country - Percentage Breakdown of Revenues for Brazil and Rest of Latin America Markets for Years 2011, 2018 & 2024 (includes corresponding Graph/Chart)
  • 8.7 Rest of World
  • A. Market Analysis
    • Current and Future Analysis
  • B. Market Analytics
    • Table 41: Rest of World Recent Past, Current and Future Analysis for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2016 through 2024 (includes corresponding Graph/Chart)
    • Table 42: Rest of World Historic Review for Bone Graft Substitutes Market Analyzed with Annual Revenue Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

9. COMPANY PROFILES Total Companies Profiled: 57 (including Divisions/Subsidiaries - 60) The United States (38) Canada (1) Europe (17) - France (2) - Germany (2) - The United Kingdom (4) - Rest of Europe (9) Asia-Pacific (Excluding Japan) (3) Africa (1)

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