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혈우병 A : 파이프라인 리뷰

Hemophilia A - Pipeline Review, H2 2019

리서치사 Global Markets Direct
발행일 2019년 12월 상품 코드 232826
페이지 정보 영문 212 Pages
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혈우병 A : 파이프라인 리뷰 Hemophilia A - Pipeline Review, H2 2019
발행일 : 2019년 12월 페이지 정보 : 영문 212 Pages

본 상품은 영문 자료로 한글과 영문목차에 불일치하는 내용이 있을 경우 영문을 우선합니다. 정확한 검토를 위해 영문목차를 참고해주시기 바랍니다.

혈우병 A는 X염색체 연쇄 열성 결손증으로 혈액 응고 제VIII 인자(FVIII)의 부족에 의해 발생하며, 유전 또는 자연 돌연변이에 의해 발병합니다. FVIII 활동의 수준에 따라 혈우병 환자는 멍이 쉽게 생기고 외상을 입어도 충분히 응고하지 않으며, 중증 혈우병은 자발성 출혈을 수반합니다. 증상은 통증과 부종을 수반하는 관절내 출혈 및 혈뇨·혈변, 멍, 소화관과 요로 출혈, 코피, 절상 및 발치, 수술시 계속되는 출혈, 돌발성 출혈 등을 들 수 있습니다.

혈우병 A(Hemophilia A) 치료제 개발 파이프라인 현황과 최신 업데이트에 의한 각 개발 단계 비교 분석, 기업과 연구기관이 개발중인 치료제, 치료제 평가, 후기 단계 및 중지된 프로젝트 관련 정보, 최신 뉴스와 발표 등의 정보를 전해드립니다.

서론

  • 조사 범위

혈우병 A 개요

치료제 개발

  • 파이프라인 제품;개요
  • 기업별 파이프라인
  • 대학/연구기관에서 개발된 파이프라인
  • 기업에서 개발중인 제품
  • 대학/연구기관에서 개발중인 제품

치료제 평가

  • 표적별
  • 작용기전별
  • 투여 경로별
  • 분자 종류별

치료제 개발 참여 기업

  • Alnylam Pharmaceuticals Inc
  • Amarna Therapeutics BV
  • Apitope International NV
  • Bayer AG
  • BioMarin Pharmaceutical Inc
  • Bioverativ Inc
  • Catalyst Biosciences Inc
  • Chugai Pharmaceutical Co Ltd
  • CSL Ltd
  • DBV Technologies SA
  • Dimension Therapeutics Inc
  • Emergent BioSolutions Inc
  • EpiVax Inc
  • Expression Therapeutics LLC
  • Green Cross Corp
  • Idogen AB
  • Immusoft Corp
  • Lentigen Technology Inc
  • mAbxience SA
  • Novo Nordisk A/S
  • OPKO Biologics Ltd
  • Pangen Biotech Inc.
  • Pfizer Inc
  • Pharming Group NV
  • Promethera Biosciences SA
  • rEVO Biologics Inc
  • Sangamo Therapeutics Inc
  • Shire Plc
  • SK Chemicals Co Ltd
  • Spark Therapeutics Inc
  • UniQure NV
  • XL-protein GmbH

약제 개요

휴지 상태의 프로젝트

개발이 중지된 제품

제품 개발 마일스톤

  • 주요 뉴스와 프레스 릴리스

부록

도표

LSH 17.07.24

List of Tables

  • Number of Products under Development for Hemophilia A (Factor VIII Deficiency), H2 2019
  • Number of Products under Development by Companies, H2 2019
  • Number of Products under Development by Companies, H2 2019 (Contd..1), H2 2019
  • Number of Products under Development by Companies, H2 2019 (Contd..2), H2 2019
  • Number of Products under Development by Universities/Institutes, H2 2019
  • Products under Development by Companies, H2 2019
  • Products under Development by Companies, H2 2019 (Contd..1), H2 2019
  • Products under Development by Companies, H2 2019 (Contd..2), H2 2019
  • Products under Development by Companies, H2 2019 (Contd..3), H2 2019
  • Products under Development by Companies, H2 2019 (Contd..4), H2 2019
  • Products under Development by Universities/Institutes, H2 2019
  • Number of Products by Stage and Target, H2 2019
  • Number of Products by Stage and Mechanism of Action, H2 2019
  • Number of Products by Stage and Route of Administration, H2 2019
  • Number of Products by Stage and Molecule Type, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Pipeline by Alveron Pharma, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Pipeline by ApcinteX Ltd, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Pipeline by Apitope International NV, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Pipeline by ASC Therapeutics Inc, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Pipeline by Ascension Healthcare Plc, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Dormant Projects, H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Dormant Projects, H2 2019 (Contd..1), H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Dormant Projects, H2 2019 (Contd..2), H2 2019
  • Hemophilia A (Factor VIII Deficiency) - Discontinued Products, H2 2019

List of Figures

  • Number of Products under Development for Hemophilia A (Factor VIII Deficiency), H2 2019
  • Number of Products under Development by Companies, H2 2019
  • Number of Products under Development by Universities/Institutes, H2 2019
  • Number of Products by Targets, H2 2019
  • Number of Products by Stage and Targets, H2 2019
  • Number of Products by Top 10 Mechanism of Actions, H2 2019
  • Number of Products by Stage and Top 10 Mechanism of Actions, H2 2019
  • Number of Products by Routes of Administration, H2 2019
  • Number of Products by Stage and Routes of Administration, H2 2019
  • Number of Products by Top 10 Molecule Types, H2 2019
  • Number of Products by Stage and Top 10 Molecule Types, H2 2019

Summary:

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hemophilia A - Pipeline Review, H2 2019, provides an overview of the Hemophilia A (Hematology ) pipeline landscape.

Hemophilia A is an X-linked, recessive disorder caused by deficiency of functional plasma clotting factor VIII (FVIII), which may be inherited or arise from spontaneous mutation. Depending on the level of FVIII activity, patients with hemophilia may present with easy bruising, inadequate clotting of traumatic injury or in the case of severe hemophilia spontaneous hemorrhage. Symptoms may include bleeding into joints, with associated pain and swelling, blood in the urine or stool, bruising, gastrointestinal tract and urinary tract hemorrhage, nosebleeds, prolonged bleeding from cuts, tooth extraction, and surgery and spontaneous bleeding.

Report Highlights:

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Hemophilia A - Pipeline Review, H2 2019, provides comprehensive information on the therapeutics under development for Hemophilia A (Hematology ), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Hemophilia A (Hematology ) pipeline guide also reviews of key players involved in therapeutic development for Hemophilia A (Factor VIII Deficiency) and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 2, 16, 8, 3, 1, 29, 7 and 1 respectively. Similarly, the Universities portfolio in Phase II and Preclinical stages comprises 1 and 4 molecules, respectively.

Hemophilia A (Hematology ) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Hemophilia A (Hematology ).
  • The pipeline guide reviews pipeline therapeutics for Hemophilia A (Hematology ) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Hemophilia A (Hematology ) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Hemophilia A (Hematology ) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Hemophilia A (Hematology )

Reasons to buy:

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Hemophilia A (Hematology ).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Hemophilia A (Hematology ) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

  • Table of Contents
    • List of Tables
    • List of Figures
  • Introduction
    • Global Markets Direct Report Coverage
  • Hemophilia A (Factor VIII Deficiency) - Overview
    • Hemophilia A (Factor VIII Deficiency) - Therapeutics Development
    • Pipeline Overview
    • Pipeline by Companies
    • Pipeline by Universities/Institutes
    • Products under Development by Companies
    • Products under Development by Universities/Institutes
  • Hemophilia A (Factor VIII Deficiency) - Therapeutics Assessment
    • Assessment by Target
    • Assessment by Mechanism of Action
    • Assessment by Route of Administration
    • Assessment by Molecule Type
  • Hemophilia A (Factor VIII Deficiency) - Companies Involved in Therapeutics Development
    • Alveron Pharma
    • ApcinteX Ltd
    • Apitope International NV
    • ASC Therapeutics Inc
    • Ascension Healthcare Plc
    • Beijing Northland Biotech Co Ltd
    • Beijing Tiantan Biological Products Co Ltd
    • BioMarin Pharmaceutical Inc
    • Cabaletta Bio Inc
    • Casebia Therapeutics
    • Catalyst Biosciences Inc
    • Chugai Pharmaceutical Co Ltd
    • CSL Ltd
    • Daiichi Sankyo Co Ltd
    • DBV Technologies SA
    • Dnarx LLC
    • EpiVax Inc
    • Expression Therapeutics LLC
    • Freeline Therapeutics Ltd
    • GC Pharma
    • Generation Bio Corp
    • Genzyme Corp
    • ID Pharma Co Ltd
    • Idogen AB
    • Immusoft Corp
    • Innovare R & D SA De CV
    • Kaifeng Pharmaceutical (Group) Co Ltd
    • Kymab Ltd
    • LambdaGen Therapeutics
    • LFB SA
    • NovalGen Ltd
    • Novo Nordisk AS
    • Octapharma AG
    • OPKO Biologics Ltd
    • Pangen Biotech Inc
    • Pfizer Inc
    • Pharming Group NV
    • Precision Biosciences Inc
    • ProFactor Pharma Ltd
    • Recursion Pharmaceuticals Inc
    • Sangamo Therapeutics Inc
    • Sanofi
    • Serpinx BV
    • Shenzhen Weiwu Guangming Biological Preparations Co Ltd
    • Sigilon Therapeutics Inc
    • Sino Biopharmaceutical Ltd
    • Sinocelltech Ltd
    • Spark Therapeutics Inc
    • Takeda Pharmaceutical Co Ltd
    • TeraImmune Inc
    • Ultragenyx Pharmaceutical Inc
    • UniQure NV
    • XL-protein GmbH
  • Hemophilia A (Factor VIII Deficiency) - Drug Profiles
  • Hemophilia A - Dormant Projects
  • Hemophilia A - Discontinued Products
  • Hemophilia A - Product Development Milestones
  • Appendix
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