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Global Gel Permeation Chromatography Market size was valued at USD 1,520.31 Million in 2023, expanding at a CAGR of 7.91% from 2024 to 2032.
Gel Permeation Chromatography (GPC), also referred to as Size Exclusion Chromatography (SEC), serves as a chromatographic method utilized for segregating and scrutinizing macromolecules based on their size and molecular weight. In GPC, a sample comprising polymers or macromolecules is introduced into a column filled with porous beads, typically crafted from cross-linked agarose or polymeric materials. During the passage of the sample through the column, smaller molecules infiltrate the beads' pores, causing them to elute more slowly, whereas larger molecules are barred and elute faster. The elution profile derived from GPC analysis furnishes insights into the molecular weight distribution of the sample, enabling researchers to profile polymer samples, ascertain average molecular weights, and evaluate polymer purity and composition. GPC finds extensive application in polymer science, biotechnology, pharmaceuticals, and materials research for tasks like quality control, formulation development, and structural analysis of macromolecular samples.
Global Gel Permeation Chromatography Market- Market Dynamics
Rise in research and development endeavors undertaken by pharmaceutical and biotechnology companies targeting chronic diseases to propel market demand
The rise in research and development endeavors undertaken by pharmaceutical and biotechnology companies targeting chronic diseases is anticipated to drive the growth of the gel permeation chromatography market. An increased emphasis on research and development activities globally, particularly focusing on chronic ailments like cancer to introduce innovative therapies, is expected to bolster market expansion. These therapies, predominantly protein-based, encompass treatments such as CAR-T cell therapy, antibody-drug conjugates, and immune checkpoint inhibitors. According to a 2017 report by the International Federation of Pharmaceutical Manufacturers and Associations, research-oriented pharmaceutical and biotechnology companies collectively invest approximately US$ 149 billion annually in global research and development efforts. There are over 7,000 molecules currently under investigation for drug development, with around 2,000 of them dedicated to cancer treatment. Consequently, the efficient separation and characterization of new chemical entities, particularly those polymer-based, are made possible through gel permeation chromatography, thereby contributing to market growth. Furthermore, the majority of these drugs under investigation are in the preclinical study phase, which involves examining the structure and components of new chemical entities, thereby necessitating the utilization of gel permeation chromatography systems.
Global Gel Permeation Chromatography Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 7.91% over the forecast period (2024-2032)
Based on Product Type segmentation, Gel Permeation Chromatography System was predicted to show maximum market share in the year 2023
Based on End User segmentation, pharmaceutical companies was the leading type in 2023
On the basis of region, North America was the leading revenue generator in 2023
The Global Gel Permeation Chromatography Market is segmented on the basis of Product Type, End User, and Region.
The market is divided into four categories based on Product Type: Gel Permeation Chromatography System, Detectors, Columns, and Pumps. Within gel permeation chromatography, the Gel Permeation Chromatography System stands out as the predominant product type segment. This dominance is primarily attributed to the extensive functionality and adaptability these systems provide in the separation and analysis of macromolecules based on their size. Gel permeation chromatography systems amalgamate various components such as detectors, columns, and pumps into an integrated platform, streamlining the analytical process and enhancing operational efficiency. Additionally, their widespread adoption across diverse industries and research domains underscores their significance in advancing scientific inquiry and facilitating quality control procedures.
The market is divided into three categories based on End User: Pharmaceutical Companies, Research Institutes and others. Based on end-users, pharmaceutical companies emerge as the dominant segment. Given the stringent regulatory standards and rigorous quality requirements prevalent in pharmaceutical manufacturing, gel permeation chromatography systems play a pivotal role in characterizing polymers, proteins, and other biomolecules essential for drug development and quality assurance endeavors. Their capability to furnish precise and reproducible outcomes renders them indispensable tools for ensuring the safety, efficacy, and uniformity of pharmaceutical products.
Global Gel Permeation Chromatography Market- Geographical Insights
Geographically, this market is widespread into the regions of North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa. These regions are further divided as per the nations bringing business.
Within the Gel Permeation Chromatography market, companies employ strategic measures to enhance product efficacy, broaden market outreach, and cater to customer requirements. Strategic alliances hold significant sway, wherein GPC instrument manufacturers collaborate with research institutions, academic laboratories, and industrial counterparts to devise tailored solutions and applications aligned with distinct research domains and industry requisites. These collaborations empower manufacturers to incorporate advanced functionalities, such as high-resolution detectors, automation capabilities, and data analysis software, into GPC systems, thereby augmenting analytical performance, throughput, and user experience. Additionally, partnerships with material suppliers and standards organizations facilitate the development of reference materials, calibration standards, and quality control protocols to ensure precision, reproducibility, and traceability in GPC analysis. Moreover, collaborations with distribution channels and service providers enable manufacturers to extend market presence and furnish comprehensive support services, encompassing technical aid, training initiatives, and maintenance contracts, to GPC users worldwide. Furthermore, strategic affiliations with regulatory bodies and industry associations bolster compliance with quality benchmarks, method validation criteria, and regulatory mandates, thereby fortifying product credibility and market acceptance.
In June 2023, Agilent unveiled new comprehensive GPC/SEC solutions at the HPLC 2023 Conference, marking a significant stride in the domain. The integration of products from Polymer Standards Service Ltd. has culminated in the most comprehensive and adaptable GPC/SEC portfolio available in the market, consolidating Agilent's position as a leader in chromatography solutions.
GLOBAL GEL PERMEATION CHROMATOGRAPHY MARKET KEY PLAYERS- DETAILED COMPETITIVE INSIGHT
Agilent Technologies
Waters Corporation
Malvern Panalytical
Shimadzu Corporation
Polymer Char
Tosoh Corporation
Gilson
Others