항체약물접합체(ADC) : 기술 및 세계 시장

The global market for antibody-drug conjugates is estimated to increase from $10.8 billion in 2023 to reach $47.0 billion by 2029, at a compound annual growth rate (CAGR) of 28.4% from 2024 through 2029.

The microtubule inhibitors market for antibody-drug conjugates is estimated to increase from $6.7 billion in 2023 to reach $25.7 billion by 2029, at a CAGR of 25.6% from 2024 through 2029.

The DNA targeting agents market for antibody-drug conjugates is estimated to increase from $4.1 billion in 2023 to reach $21.1 billion by 2029, at a CAGR of 32.2% from 2024 through 2029.

Report Scope

This report focuses on the global market for antibody-drug conjugates (ADCs), offering an updated review that covers their fundamental design and use across different oncology fields. In this report, market segmentation is based on payload, linker, antibody, indications, and region. The report also discusses current and developing technologies, market projections and market shares. An analysis of clinical trials, innovations, opportunities, and the latest trends in the ADC market are also discussed in the report.

The report only covers antibody-drug conjugates in which an antibody is conjugated with small-molecule cytotoxic agents (also called payload) through a linker. Alternative antibody conjugates, such as those involving antibodies linked to radioisotopes, are not covered in this report.

Report Includes

• 25 data tables and 45 additional tables
• An updated review of the global market for antibody drug conjugates
• Analyses of the global market trends, with data from 2021-2023, estimates for 2024, forecasts for 2025, and projections of compound annual growth rates (CAGRs) through 2029
• Evaluation of the overall market for antibody drug conjugates, and corresponding market share analysis by payload type, linker type, antibody type, indication and region
• Coverage of the latest approvals, recalls, safety alerts, and clinical trials; the technical issues related to human anti-mouse antibody (HAMA); and the factors affecting mAB drugs
• Information about major and emerging technologies for the formulation of antibody drug conjugates and assessment of their relation to biotechnology, immunology, pharmaceuticals, and biodefense companies
• Discussions of the market dynamics, opportunities and challenges
• Overview of the sustainability trends and ESG developments in the industry, with emphasis on the ESG practices followed by leading companies, their ESG ratings, and consumer attitudes
• Competitive intelligence, including companies' market shares, recent M&A activity and venture funding
• Company profiles of major players within the industry, including F. Hoffmann-La Roche Ltd., Daiichi Sankyo, Pfizer Inc., and Gilead Sciences

Table of Contents

Chapter 1 Executive Summary

• Market Outlook
• Scope of Report
• Market Summary

Chapter 2 Market Overview

• Overview
• Components of ADCs
• Drug-to-antibody Ratio (DAR)
• How ADCs Work
• Advantages of ADCs
• Conjugation Methods
• Conventional Conjugation Method
• Site-Specific Conjugation
• Key ADC Targets
• Approved ADCs

Chapter 3 Market Dynamics

• Market Dynamics Snapshot
• Market Drivers
• Rising Prevalence of Cancer and Unmet Need in Oncology
• De-risked Development
• Complexity of ADCs
• Investor Confidence in ADC Therapeutic Modality
• Support from Regulatory Agencies
• Limitations
• Technical and Manufacturing Challenges
• ADC Resistance

Chapter 4 Emerging Technologies and Developments

• Bispecific or Dual-Targeted ADCs
• Dual Payload ADCs
• ADCs in Combination with Immune Checkpoint Inhibitors
• B7-H3 Antibody Target
• Site-specific Conjugation
• Pipeline Analysis
• Payload Type
• Linker Type
• Antibody Type
• Indication Type
• Target Type
• Conjugation Method Type
• Novel ADCs in Development, by Phase

Chapter 5 Market Segmentation Analysis

• Segmentation Breakdown
• Market Analysis, by Payload Type
• Market Overview
• Market Revenue and Forecast
• Market Analysis, by Linker Type
• Market Overview
• Market Revenue and Forecast
• Market Analysis, by Type of Antibody
• Market Overview
• Market Revenue and Forecast
• Market Analysis, by Indication
• Market Overview
• Market Revenue and Forecast
• Geographic Breakdown
• Market Analysis, by Region
• North America
• Europe
• Other Regions

Chapter 6 Competitive Intelligence

• ADC Sales
• Market Share Analysis

Chapter 7 Appendix

• Methodology
• Sources
• Abbreviations
• Company Profiles
• ABBVIE INC.
• ADC THERAPEUTICS SA
• DAIICHI SANKYO CO. LTD.
• F. HOFFMANN-LA ROCHE LTD.
• GILEAD SCIENCES INC.
• PFIZER INC.