DNA 및 RNA 합성 조사 리뷰(2024년)

The global market for DNA sequencing is expected to grow from $14.8 billion in 2024 and is projected to reach $34.8 billion by the end of 2029, at a compound annual growth rate (CAGR) of 18.6% during the forecast period of 2024 to 2029.

The global market for clinical applications of next-generation sequencing is estimated to increase from $21.9 billion in 2023 to reach $52.9 billion by 2028, at a CAGR of 19.3% from 2023 through 2028.

The global market for RNA sequencing is expected to grow from $4.3 billion in 2024 and is projected to reach $10.3 billion by the end of 2029, at a CAGR of 19.1% during the forecast period of 2024 to 2029.

Research Review Scope

DNA and RNA synthesis artificially manufactures deoxyribose nucleic acid (DNA) and ribonucleic acid (RNA). Developing synthetic techniques to construct DNA and RNA has improved the ability to understand and engineer biology. Different types of synthesized DNA, such as oligonucleotides, genes, and DNA and RNA fragments, are available and can be utilized per the customer's needs. Synthetic DNA and RNA are used to develop new drugs and vaccines, gene therapies for genetic disorders, and the development of molecular diagnostic tools, including polymerase chain reaction (PCR) assays and nucleic-acid-based sensors, to detect pathogens and diseases.

DNA and RNA synthesis technology is vital in scientific fields such as synthetic biology, molecular genetics, and bioengineering, creating custom DNA and RNA sequences for various research, diagnostic, and therapeutic applications. The rapid expansion of genomics research, advancements in therapeutic DNA and RNA applications, and the growing need for personalized medicine are driving exceptional growth in the DNA & RNA synthesis market. The innovations in CRISPR, gene therapy, and synthetic biology show that the demand for DNA and RNA synthesis has risen sharply, positioning it as a pivotal tool in developing targeted treatments and innovative genetic research solutions.

Research Reviews from BCC Research provide market professionals with concise market coverage within a specific research category. This 2024 Research Review of DNA and RNA synthesis technology provides a sampling of the type of quantitative market information, analysis, and guidance that BCC Research has been developing since its inception in 1971 to help its customers make informed business decisions. This Research Review includes highlights and excerpts from the following reports published by BCC Research in 2024:

• BIO259A Gene Editing Therapeutics Market
• BIO045J Global DNA Sequencing: Research Applied and Clinical Markets
• BIO126E Next-generation Sequencing: Emerging Clinical Applications and Global Markets
• BIO147B RNA Sequencing: Technologies and Global Markets
• BIO127C RNAi Technologies and Global Markets
• BIO192B Viral Vector and Plasmid DNA: Technologies and Global Markets

After you survey the excerpts in this Research Review, we encourage you to follow up on these topics by checking out the full market research reports associated with each topic. BCC Research looks forward to serving your market intelligence needs in the future.

Table of Contents

Chapter 1 Foreword

• Research Review Scope

Chapter 2 Gene Editing Therapeutics Market (BIO259A)

• Scope of Report of Gene Editing Therapeutics
• Market Outlook of Gene Editing Therapeutics
• Market Summary
• Market Overview of Gene Editing Therapeutics
• Genome-Editing Tool Types
• Meganucleases
• Zinc Finger Nucleases
• Transcription Activator-like Effector Nucleases
• Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-Associated Protein 9
• Gene editing Therapeutics
• Market Dynamics of Gene Editing Therapeutics
• Market Driver
• Market Challenges
• Emerging Technologies and Opportunities of Gene Editing Therapeutics
• Base Editing
• Prime Editing
• Cas-Clover and Cas-FOKl
• CRISPR Interference and CRISPR Activation
• RNA Editing
• Artificial Intelligence in Genome Editing
• Market Analysis of Gene Editing Therapeutics
• Overview
• Casgevy
• Market of Gene Editing Therapeutics by Region
• North America
• Europe
• Emerging Markets
• ESG Performance in Gene Editing Therapeutics Market
• ESG Practices in the Gene Editing Companies
• Concluding Remarks from BCC Research

Chapter 3 Global DNA Sequencing: Research, Applied and Clinical Markets (BIO045J)

• Scope of Report of DNA Sequencing: Research, Applied and Clinical Markets
• Market Outlook of DNA Sequencing: Research, Applied and Clinical Markets
• Market Summary of DNA Sequencing: Research, Applied and Clinical Markets
• Market Overview of DNA Sequencing: Research, Applied and Clinical Markets
• Importance of DNA
• Genetic Variation and Analysis
• NGS (Second-generation Sequencing)
• TGS (Long-read Sequencing)
• Research and Applied Applications
• R&D Applications
• Applied Applications
• Direct to Consumer
• Biopharma
• Agriculture
• Forensics
• Microbiome
• Synthetic Biology
• Market Dynamics of DNA Sequencing: Research, Applied and Clinical Markets
• Market Driver
• Market Restraint
• Emerging Technologies of DNA Sequencing: Research, Applied and Clinical Markets
• Long-read Sequencing Technologies
• SMRT Sequencing
• Nanopore Sequencing
• Spatial Genomics and Transcriptomics
• Single-cell DNA Sequencing
• Ultra-low Input Sequencing
• CRISPR-Cas9 and Genome-editing Integration with Sequencing Technologies
• AI and Machine Learning in DNA Sequencing
• Market Breakdown of DNA Sequencing: Research, Applied and Clinical Markets by Technology
• Overview
• NGS
• TGS
• Sanger Sequencing
• Pyrosequencing
• Market Breakdown of DNA Sequencing: Research, Applied and Clinical Markets by Region
• North America
• Europe
• Asia-Pacific
• Rest of the World
• ESG Performance in DNA Sequencing Industry
• Environmental Performance
• Social Performance
• Governance Performance
• ESG Risk Ratings in the DNA Sequencing Industry
• Concluding Remarks from BCC Research

Chapter 4 Next-generation Sequencing: Emerging Clinical Applications and Global Markets (BIO126E)

• Scope of Report of Next-generation Sequencing
• Market Outlook of Next-generation Sequencing
• Market Summary of Next-generation Sequencing
• Market Overview of Next-generation Sequencing
• Liquid and Tissue Biopsy
• Growth Drivers of Clinical NGS
• Key Trends
• Market Dynamics of Next-generation Sequencing
• Market Driver
• Market Restraint
• Emerging Technologies of Next-generation Sequencing
• R&D Initiatives and Programs
• 1+ Million Genomes
• Access to Treatment and Testing (ACTT)
• Access to Comprehensive Genomic Profiling Coalition (ACGP)
• Africa Pathogen Genomics Initiative
• Blood Profiling Atlas
• Cancer-ID
• Cancer Moon Shots Program
• China Precision Medicine Initiative
• ClinGen
• CTC Trap Consortium
• diaRNAgnosis Project
• Early Cancer Detection Consortium
• EpiFemCare
• France Genomic Medicine Plan
• Friends of Cancer Research Project
• Genomic Medicine Sweden
• HCA-Organoid
• Human Cell Atlas
• Human Immunomics Initiative
• Immunomonitor Consortium
• Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy Program
• Intervene
• Liquid Biopsies and Imaging for Improved Cancer Care
• Liquid Biopsy-Based Malignant Tumor Early Screening Technology Research and Development Project
• Liver Cancer Early Screening Comprehensive Prevention and Control Project
• Lung Cancer Genomic Screening Project for Individualized Medicine in Asia
• Million Veteran Program
• Medical Genome Initiative
• MedSeq
• Market Breakdown of Next-generation Sequencing by Disease Category
• Overview
• Market Breakdown of Next-generation Sequencing by Region
• North America
• Europe
• Asia-Pacific
• ESG Performance in Next-generation Sequencing Industry
• Case Study
• BCC Research Viewpoint

Chapter 5 RNA Sequencing: Technologies and Global Markets (BIO147B)

• Scope of Report of RNA Sequencing
• Market Outlook of RNA Sequencing
• Market Summary of RNA Sequencing
• Market Overview of RNA Sequencing
• Technology Background
• Transcriptomics Technologies
• RNA Sequencing for Transcriptomics
• RNA-Seq Experimental Workflow
• Regulatory Landscape of RNA Sequencing
• Growth Strategy Recommendations
• Market Dynamics of RNA Sequencing
• Market Drivers
• Market Restraints
• Market Opportunity
• Emerging Technologies and Developments of RNA Sequencing Market
• Single-Cell RNA Sequencing
• Other Emerging Single-Cell Technologies
• Market Breakdown of RNA Sequencing by Product
• Instruments
• Tools and Reagents
• Software and Services
• Market Breakdown of RNA Sequencing by Region
• Overview
• North America
• Europe
• Asia-Pacific
• Rest of the World
• Sustainability in RNA Sequencing Market: ESG Perspective
• ESG Practices in the RNA Sequencing Industry
• Environmental Performance
• Social Performance
• Governance Performance
• Concluding Remarks from BCC Research

Chapter 6 RNAi Technologies and Global Markets ( BIO127C)

• Scope of Report of RNAi Technologies
• Market Snapshot of RNAi Technologies
• Market Summary of RNAi Technologies
• Market Overview of RNAi Technologies
• RNA Interference Overview
• RNA Interference: Mechanism of Action
• Initiation Phase
• Effector Phase
• Small Interfering RNAs (siRNAs)
• MicroRNAs (miRNAs)
• Small Hairpin RNAs (shRNAs)
• Market Dynamics of RNAi Technologies
• Market Drivers
• Market Challenges
• Emerging Technologies and Opportunities of RNAi Technologies
• Therapeutics
• Diagnostics
• Circulating miRNA Diagnostics for Non-invasive Health Monitoring
• Agriculture
• Market for RNAi Technology by Technology
• Therapeutics
• Diagnostics
• Reagents and Tools
• Agriculture
• Market for RNAi Technology by Region
• Overview
• North America
• Europe
• Emerging Markets
• Sustainability in RNAi Technology Industry: An ESG Perspective
• Environmental Initiatives
• Social Initiatives
• Governance Initiatives
• Case Study
• Concluding Remarks from BCC

Chapter 7 Viral Vector and Plasmid DNA: Technologies and Global Markets (BIO192B)

• Scope of Report of Viral Vector and Plasmid DNA
• Market Outlook of Viral Vector and Plasmid DNA
• Market Summary of Viral Vector and Plasmid DNA
• Market Overview of Viral Vector and Plasmid DNA
• Cell and Gene Therapy
• Market Dynamics of Viral Vector and Plasmid DNA
• Market Driver
• Market Challenges
• Emerging Technologies and Opportunities of Viral Vector and Plasmid DNA
• AI in Viral Vector Production
• Doggybone DNA
• FRAGment Recycler: A New Technology for Plasmid DNA Synthesis
• Market for Viral Vector and Plasmid DNA Technologies by Product Type
• Market for Viral Vector and Plasmid DNA Technologies by Application
• Market for Viral Vector and Plasmid DNA Technologies by Region
• Overview
• North America
• Europe
• Asia-Pacific
• Latin America
• Rest of the World
• Sustainability in the Market for Viral Vector and Plasmid DNA Technologies: An ESG Perspective
• Environmental Factors
• Social Factors
• Governance Factors
• ESG Performance Among Major Companies
• ESG Performance of Select Companies
• Lonza: ESG Performance
• Thermo Fisher: ESG Performance
• Conclusion

Chapter 8 Appendix

• Methodology
• Analyst's Credentials