항체매개 거부반응 시장 - 세계 및 지역/국가별 분석·예측(2025-2035년)

Global Antibody-Mediated Rejection Market, Analysis and Forecast: 2025-2035

Antibody-mediated rejection (AMR) is a type of organ transplant rejection in which the recipient's immune system produces antibodies that attack the transplanted organ. This response is different from cellular rejection, where T-cells attack the transplant. antibody-mediated rejection primarily involves the formation of antibodies that recognize and bind to foreign molecules (antigens) present on the blood vessels of the transplanted organ.

The global antibody-mediated rejection market is expanding significantly, fueled by several key factors. One of the main drivers is the growing number of organ transplant procedures worldwide, as the demand for transplants continues to rise, driven by an aging population and an increase in organ failure cases. This has created a substantial need for antibody-mediated rejection prevention, diagnosis, and treatment options. Advances in molecular biology and immunology are also facilitating better understanding and diagnosis of antibody-mediated rejection, promoting the development of targeted therapies that offer more effective management of transplant rejection.

Moreover, the increasing availability and accuracy of diagnostic tests, such as donor-specific antibody (DSA) detection and complement-dependent cytotoxicity assays, are helping to identify antibody-mediated rejection earlier, leading to better clinical outcomes and improved patient survival rates. The rising adoption of precision medicine, which tailors treatments based on genetic and immunological profiling, is another factor contributing to the market growth. This allows for more personalized and effective treatments for antibody-mediated rejection, improving transplant success rates and patient quality of life.

However, the antibody-mediated rejection market faces certain challenges that could hinder its growth. The high cost of advanced diagnostic tools and treatments can be a barrier, particularly in low- and middle-income countries with limited healthcare resources. The complexity of managing antibody-mediated rejection also requires specialized expertise, which can limit access to care in regions with underdeveloped healthcare infrastructure. Additionally, while many treatment options exist, antibody-mediated rejection is often a chronic condition that may require long-term management, placing a continuous financial burden on patients and healthcare systems alike.

Despite these challenges, leading players in the antibody-mediated rejection market, such as Sanofi, Hansa Biopharma, and Talaris Therapeutics. are focusing on research and development of new therapeutic options. Companies are exploring the potential of gene therapies, monoclonal antibodies, and other novel biologics to target the underlying causes of antibody-mediated rejection more effectively. This has spurred increased competition and innovation, with companies also striving to improve the safety and efficacy profiles of current treatments.

As the antibody-mediated rejection market evolves, several trends are expected to shape its future growth. The increasing use of machine learning and artificial intelligence in both diagnostics and treatment planning will allow for more accurate and timely intervention. The growing trend toward personalized medicine, combined with advances in organ preservation and transplant techniques, will further optimize outcomes for patients undergoing transplant procedures. In addition, heightened awareness and the development of educational initiatives for both healthcare providers and patients will help in early detection and proactive management of antibody-mediated rejection.

In conclusion, the antibody-mediated rejection market is poised for significant growth, driven by advancements in diagnostics, treatment options, and personalized medicine. With the increasing number of organ transplant procedures and the growing recognition of antibody-mediated rejection impact on patient outcomes, stakeholders in the healthcare industry, including pharmaceutical companies, medical device manufacturers, and healthcare providers, will play a pivotal role in addressing the challenges and meeting the demand for effective antibody-mediated rejection management. The continued evolution of this market will improve the quality of life for transplant recipients and ensure better transplant success rates worldwide.

Table of Contents

Executive Summary

Scope and Definition

Market/Product Definition

Inclusion and Exclusion

Key Questions Answered

Analysis and Forecast Note

1. Global Antibody-mediated Rejection Market: Industry Outlook

• 1.1 Introduction
• 1.2 Market Trends
• 1.3 Regulatory Framework
• 1.4 Epidemiology Scenario
• 1.5 Clinical Trial Analysis
• 1.6 Market Dynamics
  • 1.6.1 Impact Analysis
  • 1.6.2 Market Drivers
  • 1.6.3 Market Challenges
  • 1.6.4 Market Opportunities

2. Global Antibody-mediated Rejection Market, by Region, $Million, 2024-2035

• 2.1 North America
  • 2.1.1 Key Findings
  • 2.1.2 Market Dynamics
  • 2.1.3 Market Sizing and Forecast
    • 2.1.3.1 North America Antibody-mediated Rejection Market, by Country
      • 2.1.3.1.1 U.S.
• 2.2 Europe
  • 2.2.1 Key Findings
  • 2.2.2 Market Dynamics
  • 2.2.3 Market Sizing and Forecast
    • 2.2.3.1 Europe Antibody-mediated Rejection Market, by Country
      • 2.2.3.1.1 Germany
      • 2.2.3.1.2 U.K.
      • 2.2.3.1.3 France
      • 2.2.3.1.4 Italy
      • 2.2.3.1.5 Spain
• 2.3 Asia Pacific
  • 2.3.1 Key Findings
  • 2.3.2 Market Dynamics
  • 2.3.3 Market Sizing and Forecast
    • 2.3.3.1 Asia Pacific Antibody-mediated Rejection Market, by Country
      • 2.3.3.1.1 Japan

3. Global Antibody-mediated Rejection Market: Competitive Landscape and Company Profiles

• 3.1 Key Development and Strategies
  • 3.1.1 Mergers and Acquisitions
  • 3.1.2 Synergistic Activities
  • 3.1.3 Business Expansions and Funding
  • 3.1.4 Product Launches and Approvals
  • 3.1.5 Other Activities
• 3.2 Company Profiles
  • 3.2.1 Hansa Biopharma
    • 3.2.1.1 Overview
    • 3.2.1.2 Top Products / Product Portfolio
    • 3.2.1.3 Target Customers/End-Users
    • 3.2.1.4 Key Personnel
    • 3.2.1.5 Analyst View
  • 3.2.2 Sanofi
    • 3.2.2.1 Overview
    • 3.2.2.2 Top Products / Product Portfolio
    • 3.2.2.3 Target Customers/End-Users
    • 3.2.2.4 Key Personnel
    • 3.2.2.5 Analyst View
  • 3.2.3 Alexion
    • 3.2.3.1 Overview
    • 3.2.3.2 Top Products / Product Portfolio
    • 3.2.3.3 Target Customers/End-Users
    • 3.2.3.4 Key Personnel
    • 3.2.3.5 Analyst View

4. Research Methodology