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DNA Manufacturing Market, By Type of DNA, By Application, By Technology, By Grade, By Production Scale, By End User, By Geography

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    • WuXi AppTec
  • GenScript Biotech
  • Thermo Fisher Scientific
  • Sigma-Aldrich(Merck Group)
  • Integrated DNA Technologies
  • Eurofins Genomics
  • OriGene Technologies
  • Bluebird Bio
  • Sangamo Therapeutics
  • Cellectis
  • Caribou Biosciences
  • Editas Medicine
  • Intellia Therapeutics

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JHS 25.09.26

DNA Manufacturing Market is estimated to be valued at USD 6.44 Bn in 2025 and is expected to reach USD 19.56 Bn by 2032, growing at a compound annual growth rate (CAGR) of 17.2% from 2025 to 2032.

Report Coverage Report Details
Base Year: 2024 Market Size in 2025: USD 6.44 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 17.20% 2032 Value Projection: USD 19.56 Bn

The global DNA manufacturing market represents a rapidly evolving sector within the biotechnology industry, encompassing the production, synthesis, and commercial manufacturing of deoxyribonucleic acid (DNA) for various applications across pharmaceutical, research, diagnostic, and therapeutic domains. This market has emerged as a critical component of the modern bioeconomy, driven by unprecedented advances in genetic engineering, synthetic biology, and personalized medicine. DNA manufacturing involves sophisticated processes including chemical synthesis, enzymatic production, and bio-manufacturing techniques to create high-quality DNA constructs, plasmids, oligonucleotides, and synthetic genes.

The market serves diverse end users ranging from pharmaceutical companies developing gene therapies and vaccines to academic research institutions conducting fundamental genetic research. Key manufacturing processes include solid-phase synthesis, PCR amplification, and fermentation-based production systems that enable scalable and cost-effective DNA production. The industry has witnessed significant technological breakthroughs in automation, quality control systems, and purification methodologies, enhancing both production efficiency and product quality. As the global focus shifts toward precision medicine, gene editing technologies like CRISPR-Cas9, and next-generation therapeutics, the DNA manufacturing market continues to expand its footprint across multiple therapeutic areas including oncology, rare diseases, and infectious diseases, establishing itself as an indispensable pillar of modern biotechnological advancement.

Market Dynamics

The global DNA manufacturing market is propelled by several robust drivers that are fundamentally reshaping the biotechnology landscape and creating unprecedented growth opportunities. The primary driver stems from the exponential growth in gene therapy development, with numerous clinical trials advancing through regulatory pipelines and receiving approvals from agencies like the USFDA and EMA, creating substantial demand for high-quality therapeutic DNA products. The COVID-19 pandemic significantly accelerated market growth by highlighting the critical importance of rapid vaccine development and manufacturing capabilities, particularly for mRNA vaccines that require sophisticated DNA templates and plasmids for production. Rising investments in synthetic biology and genetic engineering research by both private and public sectors are driving demand for custom DNA synthesis services and standardized DNA components. However, the market faces notable restraints including stringent regulatory frameworks that require extensive documentation, quality control measures, and compliance with Good Manufacturing Practice (GMP) standards, which significantly increase production costs and time-to-market. The high capital investment required for establishing state-of-the-art manufacturing facilities, coupled with the need for specialized skilled personnel and advanced equipment, creates barriers for new market entrants. Technical challenges related to maintaining DNA stability, ensuring purity levels, and scaling production processes from laboratory to commercial scale continue to pose operational constraints. Nevertheless, the market presents substantial opportunities driven by the expanding applications of DNA in emerging fields such as DNA data storage, agricultural biotechnology, and environmental remediation. The growing adoption of personalized medicine approaches is creating demand for patient-specific DNA constructs and custom manufacturing services. Technological advancements in automation, artificial intelligence-driven quality control, and novel synthesis methods are opening new avenues for cost reduction and efficiency improvements, while the increasing prevalence of genetic disorders globally continues to expand the addressable market for DNA-based therapeutic solutions.

Key Features of the Study

  • This report provides in-depth analysis of the global DNA manufacturing market, and provides market size (USD Bn) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year.
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market.
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players.
  • It profiles key players in the global DNA manufacturing market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies.
  • Key companies covered as a part of this study include Lonza Group, WuXi AppTec, GenScript Biotech, Thermo Fisher Scientific, Sigma-Aldrich (Merck Group), Integrated DNA Technologies, Eurofins Genomics, OriGene Technologies, Bluebird Bio, Sangamo Therapeutics, Cellectis, Caribou Biosciences, Editas Medicine, and Intellia Therapeutics.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics.
  • The global DNA manufacturing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global DNA manufacturing market.

Market Segmentation

  • Type of DNA Insights (Revenue, USD Bn, 2020 - 2032)
    • Synthetic DNA
    • Oligonucleotide synthesis
    • Custom DNA synthesis
    • Plasmid DNA
    • Gene DNA
  • Application Insights (Revenue, USD Bn, 2020 - 2032)
    • Oncology
    • Gene Therapy
    • Vaccine Development
    • Immunotherapy
    • Regenerative Medicine
    • Neurodegenerative Diseases
    • Cardiovascular Diseases
    • Infectious Diseases
    • Others (Rare Genetic Disorders)
  • Technology Insights (Revenue, USD Bn, 2020 - 2032)
    • PCR (Polymerase Chain Reaction)
    • CRISPR/Cas9
    • Next-Generation Sequencing (NGS)
    • Gene Synthesis
    • Others (Gene Editing and Modification)
  • Grade Insights (Revenue, USD Bn, 2020 - 2032)
    • GMP Grade (Good Manufacturing Practice)
    • R and D Grade (Research and Development)
  • Production Scale Insights (Revenue, USD Bn, 2020 - 2032)
    • Commercial Scale Production
    • Custom Scale Production
  • End User Insights (Revenue, USD Bn, 2020 - 2032)
    • Pharmaceutical Companies
    • Biotechnology Companies
    • Contract Research Organizations
    • Others (Academic and Research Institutions, etc.)
  • Regional Insights (Revenue, USD Bn, 2020 - 2032)
    • North America
    • U.S.
    • Canada
    • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
    • Europe
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
    • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
    • Middle East
    • GCC Countries
    • Israel
    • Rest of Middle East
    • Africa
    • South Africa
    • North Africa
    • Central Africa
  • Key Players Insights
    • Lonza Group
    • WuXi AppTec
    • GenScript Biotech
    • Thermo Fisher Scientific
    • Sigma-Aldrich (Merck Group)
    • Integrated DNA Technologies
    • Eurofins Genomics
    • OriGene Technologies
    • Bluebird Bio
    • Sangamo Therapeutics
    • Cellectis
    • Caribou Biosciences
    • Editas Medicine
    • Intellia Therapeutics

Table of Contents

1. Research Objectives and Assumptions

  • Research Objectives
  • Assumptions
  • Abbreviations

2. Market Purview

  • Report Description
    • Market Definition and Scope
  • Executive Summary
    • Global DNA Manufacturing Market, By Type of DNA
    • Global DNA Manufacturing Market, By Application
    • Global DNA Manufacturing Market, By Technology
    • Global DNA Manufacturing Market, By Grade
    • Global DNA Manufacturing Market, By Production Scale
    • Global DNA Manufacturing Market, By End User
    • Global DNA Manufacturing Market, By Region

3. Market Dynamics, Regulations, and Trends Analysis

  • Market Dynamics
  • Driver
  • Restraint
  • Opportunity
  • Impact Analysis
  • Key Developments
  • Regulatory Scenario
  • Product Launches/Approvals
  • PEST Analysis
  • PORTER's Analysis
  • Merger and Acquisition Scenario
  • Industry Trends

4. Global DNA Manufacturing Market, By Type of DNA, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • Synthetic DNA
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
      • Oligonucleotide synthesis
      • Custom DNA synthesis
  • Plasmid DNA
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Gene DNA
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

5. Global DNA Manufacturing Market, By Application, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • Oncology
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Gene Therapy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Vaccine Development
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Immunotherapy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Regenerative Medicine
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Neurodegenerative Diseases
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Cardiovascular Diseases
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Infectious Diseases
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Others (Rare Genetic Disorders)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

6. Global DNA Manufacturing Market, By Technology, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • PCR (Polymerase Chain Reaction)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • CRISPR/Cas9
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Next-Generation Sequencing (NGS)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Gene Synthesis
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Others (Gene Editing and Modification)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

7. Global DNA Manufacturing Market, By Grade, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • GMP Grade (Good Manufacturing Practice)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • R and D Grade (Research and Development)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

8. Global DNA Manufacturing Market, By Production Scale, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • Commercial Scale Production
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Custom Scale Production
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

9. Global DNA Manufacturing Market, By End User, 2020-2032, (USD Bn)

  • Introduction
    • Market Share Analysis, 2025 and 2032 (%)
    • Y-o-Y Growth Analysis, 2021 - 2032
    • Segment Trends
  • Pharmaceutical Companies
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Biotechnology Companies
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Contract Research Organizations
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
  • Others (Academic and Research Institutions, etc.)
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

10. Global DNA Manufacturing Market, By Region, 2020 - 2032, Value (USD Bn)

  • Introduction
    • Market Share (%) Analysis, 2025, 2028 & 2032, Value (USD Bn)
    • Market Y-o-Y Growth Analysis (%), 2020 - 2032, Value (USD Bn)
    • Regional Trends
  • North America
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
      • U.S.
      • Canada
  • Latin America
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
  • Europe
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
  • Asia Pacific
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
  • Middle East
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
      • GCC Countries
      • Israel
      • Rest of Middle East
  • Africa
    • Introduction
    • Market Size and Forecast, By Type of DNA, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Application, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Technology, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Grade, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Production Scale, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
    • Market Size and Forecast, By Country/Region, 2020 - 2032, Value (USD Bn)
      • South Africa
      • North Africa
      • Central Africa

11. Competitive Landscape

  • Lonza Group
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
  • Strategies
    • WuXi AppTec
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • GenScript Biotech
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Thermo Fisher Scientific
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Sigma-Aldrich (Merck Group)
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Integrated DNA Technologies
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Eurofins Genomics
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • OriGene Technologies
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Bluebird Bio
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Sangamo Therapeutics
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Cellectis
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Caribou Biosciences
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Editas Medicine
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Intellia Therapeutics
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies

12. Analyst Recommendations

  • Wheel of Fortune
  • Analyst View
  • Coherent Opportunity Map

13. References and Research Methodology

  • References
  • Research Methodology
  • About us
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