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“"JAKAFI Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about JAKAFI for Bronchiolitis Obliterans Syndrome (BOS) in the seven major markets. A detailed picture of the JAKAFI for bronchiolitis obliterans syndrome in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the JAKAFI for bronchiolitis obliterans syndrome. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the JAKAFI market forecast analysis for bronchiolitis obliterans syndrome in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in bronchiolitis obliterans syndrome.
JAKAFI (also known as Ruxolitinib) is an oral kinase inhibitor. It inhibits JAK1 and JAK2, which mediate the signaling of several cytokines and growth factors important for hematopoiesis and immune function. JAK signaling involves the recruitment of STATs (signal transducers and activators of transcription) to cytokine receptors, activation, and subsequent localization of STATs to the nucleus leading to modulation of gene expression. The drug is indicated for the treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis in adults; polycythemia vera in adults who have had an inadequate response to or are intolerant of hydroxyurea; and steroid-refractory acute graft-versus-host disease in adult and pediatric patients 12 years and older (Incyte Corporation, 2020).
Currently, studies on ruxolitinib administration in patients with BOS are still in the preliminary stage, with only two published case series, which indicated ruxolitinib is an effective steroid-sparing agent in BOS due to cGVHD. However, the effect of ruxolitinib on pulmonary function, its toxicity profile, and the factors affecting its response have not been fully determined.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of JAKAFI for bronchiolitis obliterans syndrome in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2029 to 2032.
The report provides the clinical trials information of JAKAFI for bronchiolitis obliterans syndrome covering trial interventions, trial conditions, trial status, start and completion dates.