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“"INO-5401 + INO-9012 + LIBTAYO Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about INO-5401 + INO-9012 + LIBTAYO for glioblastoma multiforme (GBM) in the seven major markets. A detailed picture of the INO-5401+ INO-9012 + LIBTAYO for GBM in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the INO-5401+ INO-9012 + LIBTAYO for GBM. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the INO-5401+ INO-9012 + LIBTAYO market forecast analysis for GBM in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in GBM.
INO-5401, being developed by Inovio for cancer treatment, is T-cell activating DNA immunotherapy. INO 5401 encodes multiple antigens, including Inovio's SynCon antigens for human telomerase (hTERT), Wilms tumor gene-1 (WT1), and PSMA are prevalent in multiple cancers. Besides, INO-9012 is an investigational DNA-based cancer vaccine developed by the same company. It consists of a DNA molecule (plasmid) that encodes for interleukin-12 (IL-12), which is an inflammatory molecule naturally produced by various immune cells (such as macrophages and dendritic cells) in response to foreign invasion. Currently, the treatment is being studied in combination with other experimental therapies for treating many types of cancers and viral infections.
INO-9012 is administered into the patient's muscle by electroporation, which uses electric shocks to introduce DNA into cells. Upon administration, the patient's cells read the DNA to produce IL-12, which activates the immune system by promoting the growth of specialized immune cells called T cells. T cells then stimulate the production of another cell-signaling molecule called interferon-gamma (IFN-γ), activating other types of immune cells, such as natural killer cells (NK cells) and killer T cells, against tumor cells or virus-infected cells resulting in the inhibition of their growth and their killing. In its annual report 2021, the company mentioned the Phase I/II immuno-oncology trial of INO-5401 and INO-9012 (IL-12 plasmid) in participants with newly diagnosed glioblastoma multiforme (GBM), in combination with cemiplimab developed jointly by Regeneron Pharmaceuticals and Sanofi has been completed.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of INO-5401+ INO-9012 + LIBTAYO for glioblastoma multiforme (GBM) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2026 to 2032.
The report provides the clinical trials information of INO-5401+ INO-9012 + LIBTAYO for GBM covering trial interventions, trial conditions, trial status, start and completion dates.