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시장보고서
상품코드
1439693
DNA 시퀀싱 시장 : 시장 인사이트, 경쟁 환경 및 시장 예측(-2030년)DNA Sequencing - Market Insights, Competitive Landscape, and Market Forecast - 2030 |
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세계 DNA 시퀀싱 시장 규모는 2023년 107억 달러에 달했습니다. 이 시장은 2024년부터 2030년까지 예측 기간 동안 18.02%의 연평균 복합 성장률(CAGR)로 확대되어 2030년까지 288억 5,000만 달러에 달할 것으로 예상됩니다. 암 및 염색체 이상과 같은 유전적 원인을 가진 다양한 질병의 유병률 증가, 표적 치료에 대한 수요 증가로 인한 맞춤 의료의 인기 증가, 3세대 시퀀싱과 같은 신기술 개발로 이어지는 기술 발전 증가 등의 요인이 DNA 시퀀싱 시장을 견인할 것으로 추정됩니다. 또한, 유전질환뿐만 아니라 감염성 질환 및 시장 개발에 대한 산학연 연구 관심 증가는 예측 기간(2024-2030년) 동안 DNA 시퀀싱 시장을 더욱 촉진할 것으로 예상됩니다.
DNA 시퀀싱 시장 수요를 촉진하는 가장 두드러진 요인 중 하나는 유전성 질환의 유병률 증가로, Department of Health &Social Care, United Kingdom(2023)에 따르면, 희귀질환은 개별적으로는 매우 드물지만, 집단적으로 보면 상당히 흔합니다. 예를 들어, 위의 출처에 따르면 전 세계 17명 중 1명이 희귀질환을 앓고 있다고 합니다. 또한, 영국에서만 350만 명 이상이 희귀질환을 앓고 있다고 밝혔습니다. 또한 세계경제포럼(2020년 2월) 자료에 따르면 전 세계 인구의 약 10%(4억 7,500만 명)가 희귀질환을 앓고 있는 것으로 나타났습니다. 또한, 인도 보건가족복지부(2023년)는 전 세계에 7,000여 개의 희귀질환이 있으며, 그 중 72%가 유전적 질환이라고 밝혔습니다. 희귀질환은 식별이 어려운 경우가 많아 진단을 받지 못하거나 오진으로 이어지는 경우가 많습니다. 전장 유전체 염기서열 분석과 같은 DNA 시퀀싱은 단일 분석으로 여러 변이 유형을 검출할 수 있는 등의 이점을 제공하여 진단 분야와 작업 효율을 향상시킬 수 있습니다.
이 보고서는 세계 DNA 시퀀싱 시장에 대해 조사했으며, 시장 개요와 함께 제품/서비스별, 기술별, 용도별, 최종사용자별, 지역별 동향, 시장 진출기업 프로파일 등의 정보를 제공합니다.
DNA Sequencing Market By Products & Services (Instruments, Consumbales, And Services), By Technology (Sanger Sequencing, Next-Generation Sequencing, And Long-Read Sequencing), By Application (Disease Diagnosis, Precision Medicine, And Research), By End User (Hospitals & Clinics, Diagnostic Laboratories, Pharmaceutical Companies, And Academic Institutes), and by geography is estimated to grow at an appreciable CAGR forecast till 2030 owing to rising prevalence of genetic disorders and growing popularity of precision medicine
Global DNA sequencing market was valued at USD 10.70 billion in 2023, growing at a CAGR of 18.02% during the forecast period from 2024 to 2030, in order to reach USD 28.85 billion by 2030. Factors such as rising prevalence of various diseases with genetic causes such as cancers and chromosomal disorders, growing popularity of personalized medicine due to rising demand for targeted therapies, as well as rising technological advancements leading to the development of newer technologies such as third-generation sequencing are estimated to take the DNA sequencing market forward. Additionally, the growing focus on research in both industry and academia on genetic as well as infectious diseases and drug development is further expected to boost the market for DNA sequencing during the forecast period (2024-2030).
DNA Sequencing Market Dynamics:
One of the most prominent factors driving the demand for DNA sequencing market is the increasing prevalence of genetic disorders. As per the Department of Health & Social Care, United Kingdom (2023), rare diseases though quite uncommon individually, are collectively quite common. For instance, as per the source stated above, 1 in 17 people are affected by a rare condition across the globe. The source further stated that in the UK alone, rare diseases affect over 3.5 million people. Furthermore, the data from the World Economic Forum (February 2020) mentioned that nearly 10% of the global population (475 million) people were affected by a rare condition. The Ministry of Health and Family Welfare, India (2023) also states that there are as many as 7,000 rare diseases across the globe out of which 72% are of genetic origins. Rare diseases are often difficult to identify and either remain undiagnosed or result in misdiagnosis. DNA sequencing such as whole genome sequencing offer advantages such as detection of multiple variant types in a single assay thereby providing improved diagnostic field and operation efficiency. Considering such benefits of DNA sequencing, some countries are extensively focusing on genome programs in order to provide better healthcare facilities to patients. The NHS Long Term Plan by the UK government plans to build on the 100,000 genomes program and sequence 500,000 whole genomes by 2023/24 - helping those with a rare disease receive a diagnosis that otherwise would not have been possible. Thus, the market for DNA sequencing is expected to witness remarkable market growth during the forecast period (2024-2030) due to increasing prevalence of rare genetic disorders collectively and the increasing emphasis on identifying the genetic mutations.
Furthermore, another key contributor in the growing popularity of DNA sequencing is the increasing prominence of precision medicine in cancer care. The concept of "precision medicine" or individualizing the treatment plan according to the biological behavior of the tumor is considered a new approach in cancer management. The clinical applications of precision medicine are diverse encompassing screening, diagnosis, prognosis, prediction of treatment response and resistance, early detection of recurrence/metastasis, and biologic cancer stratification. Precision medicine in cancer care is aimed at bringing about therapeutic effects in subset of patients displaying specific molecular/predictive biomarkers. The customization of treatment specific to the patient's genetic makeup has gained widespread acceptance and attention from physicians. DNA sequencing has been a key component in driving the concept of precision medicine. Advanced sequencing techniques such as next generation sequencing help map the oncogenes and also in tumor analysis and helping develop specific therapeutic agents. Moreover, advantages associated with the technologies such as the simultaneous analysis of a broad spectrum of genetic alterations, including copy number variations, mutations, fusions in multiple genes, and translocations. This resulted in more personalized drugs being approved by regulatory bodies across the globe. For instance, as per the US Food and Drug Administration, out of the total drugs approved in the country in 2020, 39% were categorized as personalized medicine. Therefore, the growing prominence of precision medicine and its advantages in disease management are expected to contribute to the growth of DNA sequencing market during the forecast period.
However, technology-related challenges such as sequence alignment, problems with mapping multiple reads and high cost of technology may prove to be restraining factors to the DNA sequencing market growth.
Unlike majority of the markets, the DNA sequencing market witnessed a positive trend during the COVID-19 pandemic. There was an exponential increase in the demand for DNA sequencing products and services across the globe due to the exigent need for sequencing the SARS COV-2 virus genome. Even though other domains where DNA sequencing is employed were affected the lockdown restrictions, the dire need for sequencing the genome of the novel strain of the SARS-CoV-2 virus and the subsequent development of vaccines kept the momentum of the DNA sequencing market. With the return of normalcy across the globe, the future outlook for the DNA sequencing market looks positive during the forecast period.
DNA Sequencing Market Segment Analysis:
DNA Sequencing Market by Products & Services (Instruments, Consumables, and Services), by Technology (Sanger Sequencing, Next-Generation Sequencing, and Long-Read Sequencing), by Application (Disease Diagnosis, Precision Medicine, and Research), By End User (Hospitals & Clinics, Diagnostic Laboratories, Pharmaceutical Companies, and Academic Institutes), and by Geography (North America, Europe, Asia-Pacific, and Rest of the World)
In the technology segment of the DNA sequencing market, the long-read sequencing category is expected to show tremendous potential in revenue growth during the forecast years. This can be ascribed to the advantages associated with long-read sequencing over other DNA sequencing technologies. Long-read sequencing is the emerging technology in DNA sequencing and offers various advantages over NGS and Sanger sequencing. Short-read sequencing though being cost-effective and accurate, also becomes challenging in terms of reconstructing and counting the fragments. Such limitations are overcome by long-read sequencing as the technology allows for reading longer stretches of DNA, subsequently helping de novo assembly, mapping certainty, transcript isoform identification, and detection of structural variants. Two most prominent long-read sequencing technologies are SMRT® sequencing technology by Pacific Biosystems and Oxford Nanopore Technologies. Thus, considering the advantages associated with long-read sequencing technology, this category is estimated to perform well in coming years.
North America is expected to dominate the DNA Sequencing Market:
Among all the regions, North America is estimated to amass the largest revenue share in the global DNA sequencing market. This can be ascribed to the high prevalence of cancers, and a supportive regulatory environment among other factors in the region. Furthermore, high disposable income, sophisticated healthcare infrastructure, and increased awareness regarding new sequencing methods and programs also expected to aid in the DNA sequencing market growth in this region.
One of the key supporting factors for the growth of the North America DNA sequencing market is the increasing prevalence of cancers in the United States. As per the figures mentioned by the American Cancer Society, in 2022, it was estimated that 1.9 million new cancer cases would have been diagnosed in the United States. The data provided by the Centers for Disease Control and Prevention (2023), in 2018, 1,708,921 new cases of cancers were reported. For instance, the American Cancer Society estimates that in 2022, approximately 287,850 new cases of invasive breast cancer are expected to be diagnosed in women in the United States. Therefore, the increasing incidence of cancers such as breast cancer in the country is expected to further drive the demand for DNA sequencing such as next-generation sequencing for tumor analysis and identification of prognostic biomarkers thereby contributing in the growth of the United States DNA sequencing market as well the overall growth of the North America DNA sequencing market.
Furthermore, the growing emphasis on genome sequencing such as human genome project and also establishing DNA sequences of other infectious microorganisms. For instance, in April 2022, Biden administration announced USD 1.7 billion investments in managing the spread of COVID-19 variants in the country. The funds were aimed at helping the CDC to improve their sequencing abilities to identify variants of the SARS-CoV-2 virus. There is also a key focus on developing a National Bioinformatics Infrastructure in the country and this investment is thought to support bioinformatics throughout the U.S. public health system, creating a unified system for sharing and analyzing sequence data in a way that protects privacy but allows more informed decision-making.
Thus, all the factors stated above are estimated to contribute in the growth of the United States DNA sequencing market leading to the overall growth of the North America DNA sequencing market.
DNA Sequencing Market Key Players:
Some of the key market players operating in the DNA sequencing market includes Agilent Technologies Inc., Biorad Laboratories Ltd, Danaher Corporation, F. Hoffmann-La Roche Ltd, Illumina Inc, PerkinElmer Inc, Merck & Co., Inc, QIAGEN, Thermo Fisher Scientific, PacBio, Macrogen Inc, Oxford Nanopore Technologies plc, CD Genomics, Takara Bio Inc, Promega Corporation, BGI, 10x Genomics, Eurofins Genomics, GENEWIZ (Azenta Life Sciences), and others.
Recent Developmental Activities in DNA Sequencing Market:
In May 2020, F. Hoffman La Roche Ltd. acquired Stratos Genomics, an early-stage sequencing technology company to advance the development of Roche's nanopore sequencer.
In January 2020, Agilent Technologies introduced a new product designed to address key challenges that laboratories encounter when preparing DNA sequencing libraries for their research. The new Agilent SureSelect XT HS2 DNA Kit represents the state-of-the-art in library preparation and target enrichment, offering researchers a complete solution that allows them to choose workflow options that best suit their needs.
Key Takeaways from the DNA Sequencing Market Report Study:
Target Audience who can be benefited from this DNA Sequencing Market Report Study:
Frequently Asked Questions for DNA Sequencing Market:
DNA sequencing is essentially a technique to identify the sequence of the nucleotide base pairs (adenine, guanine, cytosine, and thymine) which form the basis of key genetic information. The knowledge of this sequence helps in disease diagnosis, therapy selection, establishing ancestry among other things.
Global DNA sequencing market was valued at USD 10.70 billion in 2023, growing at a CAGR of 18.02% during the forecast period from 2024 to 2030, in order to reach USD 28.85 billion by 2030.
Factors such as rising prevalence of various diseases with genetic causes such as cancers and chromosomal disorders, growing popularity of personalized medicine, as well as rising technological advancements leading to the development of newer technologies such as third-generation sequencing are estimated to take the DNA sequencing market forward. Additionally, the growing focus on research in both industry and academia on genetic as well as infectious diseases and drug development is further expected to boost the market for DNA sequencing during the forecast period (2024-2030).
Some of the key market players operating in the DNA sequencing market includes Agilent Technologies Inc., Biorad Laboratories Ltd, Danaher Corporation, F. Hoffmann-La Roche Ltd, Illumina Inc, PerkinElmer Inc, Merck & Co., Inc, QIAGEN, Thermo Fisher Scientific, PacBio, Macrogen Inc, Oxford Nanopore Technologies plc, CD Genomics, Takara Bio Inc, Promega Corporation, BGI, 10x Genomics, Eurofins Genomics, GENEWIZ (Azenta Life Sciences), and others.
Among all the regions, North America is estimated to amass the largest revenue share in the global DNA sequencing market. This can be ascribed to the high prevalence of cancers, and a supportive regulatory environment among other factors in the region. Furthermore, high disposable income, sophisticated healthcare infrastructure, and increased awareness regarding new sequencing methods and programs also expected to aid in the DNA sequencing market growth in this region.