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Ÿ¹ÙÆÄµ·(Tavapadon) ½ÃÀå : ½ÃÀå ±Ô¸ð, ¿¹Ãø ¹× »õ·Î¿î ÀλçÀÌÆ®(-2032³â)Tavapadon Market Size, Forecast, and Emerging Insight - 2032 |
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"Tavapadon Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about tavapadon for Parkinson's disease in the seven major markets. A detailed picture of the tavapadon for Parkinson's Disease in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the tavapadon for Parkinson's Disease. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the tavapadon market forecast analysis for Parkinson's disease in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in Parkinson's disease.
Cerevel Therapeutics is developing tavapadon to treat both early and late-stage Parkinson's disease. Tavapadon was rationally designed as an orally-bioavailable, once-daily partial agonist that selectively targets dopamine D1/D5 receptor subtypes to balance meaningful motor activity with a favourable safety profile.
It has the potential to be used as both, a monotherapy for early-stage Parkinson's disease and as adjunctive therapy for late-stage Parkinson's disease. Cerevel is currently conducting Phase III trials of tavapadon, known as TEMPO-1, TEMPO-2, and TEMPO-3, as monotherapy (early-stage) and adjunctive (late-stage) in Parkinson's disease. It is also conducting an open-label extension trial, known as TEMPO-4. Cerevel expects data from the TEMPO-3 trial in mid-year 2024 and TEMPO-1 and TEMPO-2 in the second half of 2024.
Mechanism of Action
Tavapadon differentially activates the direct motor pathway, potentially driving motor benefit while minimizing side effects typical of drugs that non-selectively stimulate dopamine, such as daytime sedation, or somnolence, compromised impulse control, and risk of psychotic symptoms including hallucinations. The drug is also designed to activate the D1/D5 receptor subtypes at levels that maximize motor benefit while reducing the prolonged receptor overexcitation and desensitization caused by full agonists, leading to dyskinesias and exacerbation of "off" time.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
Tavapadon Analytical Perspective by DelveInsight
This report provides a detailed market assessment of tavapadon for Parkinson's disease in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2025 to 2032.
The report provides the clinical trials information of tavapadon for Parkinson's disease covering trial interventions, trial conditions, trial status, start and completion dates.