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시장보고서
상품코드
1609435
듀피젠트 시장 : 시장 규모, 예측, 새로운 인사이트(-2032년)DUPIXENT Market Size, Forecast, and Emerging Insight - 2032 |
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듀피젠트(dupilumab)는 인터류킨-4(IL-4)와 인터류킨-13(IL-13) 수용체 복합체에 공통적으로 존재하는 IL-4Ra 서브유닛에 특이적으로 결합하여 인터류킨-4(IL-4)와 인터류킨-13(IL-13)의 신호전달을 억제하는 인간형 단클론항체입니다. 듀피루맙은 'i형' 수용체를 통해 IL-4의 신호전달을 억제하고, 'II형' 수용체를 통해 IL-4와 IL-13의 신호전달을 모두 억제합니다.
IL-4Ra를 발현하는 여러 세포 유형(예: 비만세포, 호산구, 대식세포, 대식세포, 림프구, 상피세포, 컵세포)과 염증 매개체(예: 히스타민, 에이코사노이드, 류코트리엔, 사이토카인, 케모카인 등)가 염증에 관여합니다. 듀피루맙으로 IL4Ra를 억제하면 염증성 사이토카인, 케모카인, 산화질소, IgE의 방출을 포함한 IL-4 및 IL-13 사이토카인에 의한 염증 반응이 억제됩니다.
듀피젠트는 아토피 피부염, 천식, 비강 용종증을 동반한 만성 비부비동염(CRSwNP), 호산구성 식도염, 결절성 소양증 등 다양한 적응증으로 승인됐습니다.
이 보고서는 미국, EU 4개국(독일, 프랑스, 이탈리아, 스페인), 영국, 일본 등 주요 7개국의 CSU용 듀피젠트에 대한 2019년부터 2032년까지 상세한 현황과 CSU용 듀피젠트에 대한 자세한 설명을 함께 게재하고 있습니다. 또한 작용기전, 용법 및 용량, 규제 마일스톤을 포함한 연구개발 및 기타 개발 활동에 대한 인사이트를 제공합니다. 또한 주요 7개국 CSU용 듀피젠트 시장 예측 분석, SWOT, 애널리스트의 견해, 시장 경쟁사 개요, CSU용 다른 신흥 치료제 개요 등 향후 시장 평가도 포함돼 있습니다.
"DUPIXENT Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about DUPIXENT for Chronic Spontaneous Urticaria (CSU) in the seven major markets. A detailed picture of the DUPIXENT for CSU in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the DUPIXENT for CSU. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the DUPIXENT market forecast analysis for CSU in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in CSU.
DUPIXENT (dupilumab) is a human monoclonal IgG4 antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling by specifically binding to the IL-4Ra subunit shared by the IL-4 and IL-13 receptor complexes. Dupilumab inhibits IL-4 signaling via the 'Type I' receptor and both IL-4 and IL-13 signaling through the 'Type II receptor'.
Multiple cell types that express IL-4Ra (e.g., mast cells, eosinophils, macrophages, lymphocytes, epithelial cells, goblet cells) and inflammatory mediators (e.g., histamine, eicosanoids, leukotrienes, cytokines, chemokines) are involved in inflammation. Blocking IL4Ra with dupilumab inhibits IL-4 and IL-13 cytokine-induced inflammatory responses, including releasing proinflammatory cytokines, chemokines, nitric oxide, and IgE.
DUPIXENT is approved for multiple indications, including atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis (CRSwNP), eosinophilic esophagitis, and prurigo nodularis.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
DUPIXENT Analytical Perspective by DelveInsight
This report provides a detailed market assessment of DUPIXENT for Chronic Spontaneous Urticaria (CSU) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2024 to 2032.
The report provides the clinical trials information of DUPIXENT for Chronic Spontaneous Urticaria (CSU) covering trial interventions, trial conditions, trial status, start and completion dates.