세계의 골수증식성 질환 치료 시장 : 시장 인사이트, 경쟁 구도, 시장 예측(2032년)

Myeloproliferative Disorder Treatment Market by Drug Class (Inhibitors [JAK Inhibitors, Tyrosine Kinase Inhibitors, STAMP Inhibitor, and Protein Synthesis Inhibitor], and Interferons), Treatment Type (Targeted Therapy, Immunotherapy, and Chemotherapy), Indication (Chronic Myeloid Leukemia (CML), Polycythemia Vera (PV), Myelofibrosis, and Essential Thrombocythemia (ET)), Route of Administration (Oral and Subcutaneous), Distribution Channel (Retail & Hospital Pharmacies and Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, and Rest of the World) is expected to grow at a steady CAGR forecast till 2032 owing to the rising prevalence of myeloproliferative disorders and advancements in molecular diagnostics and targeted therapies.

The myeloproliferative disorder treatment market is estimated to grow at a CAGR of 4.91% during the forecast period from 2025 to 2032. The demand for myeloproliferative disorder (MPD) treatment is experiencing a significant surge, driven by a convergence of critical factors that highlight the market's strong growth trajectory. Foremost among these is the increasing prevalence of MPDs, fueled by an aging global population, heightened disease awareness, and improved diagnostic capabilities. Parallel to this, rapid advancements in molecular diagnostics and the development of targeted therapies have revolutionized the management of these disorders enabling earlier detection, more precise treatment regimens, and improved patient outcomes. Collectively, these trends are cultivating a highly favorable landscape for sustained innovation and investment, positioning the MPD treatment market for robust and enduring growth over the forecast period from 2025 to 2032.

Myeloproliferative Disorder Treatment Market Dynamics:

According to the Leukaemia Foundation (2025), in Australia, approximately 250 new cases of polycythemia vera and 200 cases of essential thrombocythemia were diagnosed each year. Myelofibrosis accounted for around 150 annual diagnoses, while rarer subtypes of myeloproliferative neoplasms (MPNs) collectively affected fewer than 50 individuals per year.

Therefore, the rising cases of myeloproliferative disorders including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF) are significantly expanding the global patient population. This growing disease burden is driving an increased demand for effective, targeted, and long-term treatment options that can help manage symptoms, enhance quality of life, and reduce the risk of complications.

In the United States, the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (2023), estimated that nearly 20,000 new cases of MPNs were diagnosed annually, with approximately 295,000 people living with that condition.

Similarly, data from the National Institutes of Health (2023) indicated that MPNs affect approximately 8 out of every 100,000 individuals in the UK. Such cases are driving the demand for effective treatments for myeloproliferative disorders that work by suppressing bone marrow activity to reduce the production of excess blood cells.

Moreover, leading players in the market are increasingly investing in research and development (R&D) activities aimed at developing and commercializing innovative therapies for the treatment of myeloproliferative disorders. For example, in December 2024, Vanda Pharmaceuticals Inc. announced that the U.S. Food and Drug Administration (FDA) had granted Orphan Drug Designation to VGT-1849A, an investigational, selective antisense oligonucleotide (ASO)-based JAK2 inhibitor developed for the treatment of polycythemia vera (PV), a rare hematologic malignancy. Such regulatory milestones and product advancements are anticipated to significantly drive the growth of the myeloproliferative disorder treatment market.

As awareness of these conditions grows, along with improvements in diagnostic capabilities and disease monitoring, more patients are being identified and managed effectively. These trends are expected to drive substantial growth in the myeloproliferative disorder treatment market over the forecast period from 2025 to 2032.

However, the complications & safety concerns associated with myeloproliferative disorder drugs and stringent regulatory approvals, among others are some of the key constraints that may limit the growth of the myeloproliferative disorder treatment market.

Myeloproliferative Disorder Treatment Market Segment Analysis:

Myeloproliferative Disorder Treatment Market by Drug Class (Inhibitors [JAK Inhibitors, Tyrosine Kinase Inhibitors, STAMP Inhibitor, and Protein Synthesis Inhibitor], and Interferons), Treatment Type (Targeted Therapy, Immunotherapy, and Chemotherapy), Indication (Chronic Myeloid Leukemia (CML), Polycythemia Vera (PV), Myelofibrosis, and Essential Thrombocythemia (ET)), Route of Administration (Oral and Subcutaneous), Distribution Channel (Retail & Hospital Pharmacies and Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, and Rest of the World)

In the drug class segment of the myeloproliferative disorder treatment market, the JAK inhibitors (JAKis) category category is estimated to account for the largest market share in 2024. The growth of the category is mainly attributed to the rising prevalence of conditions such as myelofibrosis (MF) and polycythemia vera (PV). This growth is further supported by the demonstrated clinical efficacy, expanding therapeutic applications, and product approvals of these targeted drugs.

JAK inhibitors have proven effective in significantly reducing spleen size, relieving burdensome constitutional symptoms such as fatigue, night sweats, and bone pain, and improving overall quality of life, particularly in patients with MF. In PV, these agents are especially beneficial in maintaining hematocrit control in cases where conventional treatments, such as hydroxyurea, are either insufficient or poorly tolerated.

Notable therapies like Ruxolitinib and Fedratinib have delivered substantial clinical benefits, particularly for patients who are resistant to or intolerant of standard treatments. These drugs not only improve hematologic parameters but also demonstrate the potential to extend survival, reinforcing their central role in the evolving management of myeloproliferative neoplasms (MPNs). The surge in this category is further strengthened by continued innovation from leading pharmaceutical companies. For example, in July 2023, Karyopharm Therapeutics received Fast Track Designation from the U.S. Food and Drug Administration (FDA) for Selinexor, a novel agent being developed for the treatment of myelofibrosis, including primary MF, post-essential thrombocythemia MF, and post-polycythemia vera MF. Such regulatory milestones not only validate the therapeutic potential of these drugs but also help accelerate their development and market availability.

The oral administration and generally manageable safety profile of JAK inhibitors, coupled with regulatory approvals from key agencies such as the FDA and European Medicines Agency (EMA), have further facilitated their adoption in routine clinical practice. Additionally, ongoing research into the use of JAK inhibitors in essential thrombocythemia (ET) and combination treatment regimens is broadening their therapeutic utility across the MPN spectrum. As awareness of myeloproliferative neoplasms continues to rise and the paradigm shifts toward more personalized, targeted treatment approaches, demand for advanced therapies like JAK inhibitors is expected to increase steadily. This trend positions JAK inhibitors as a cornerstone in the future landscape of MPD treatment.

Thus, due to the above-mentioned factors, the JAK inhibitors sub-category is expected to register significant growth, thereby driving the growth of the overall myeloproliferative disorder treatment market during the forecast period from 2025 to 2032.

North America is expected to dominate the overall myeloproliferative disorder treatment market:

North America is expected to hold the largest share of myeloproliferative disorder treatment in 2024. This dominance is primarily attributed to the high prevalence of conditions such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), coupled with greater disease awareness among healthcare providers and patients. Additionally, increasing R&D activities and product launches by key market players further contribute to the region's strong market position.

According to data from the American Cancer Society (2025), in the United States, approximately 9,560 new cases of chronic myeloid leukemia (CML) are diagnosed each year, with around 5,610 cases in men and 3,950 in women. CML accounted for about 15% of all newly diagnosed leukemia cases, and the lifetime risk of developing CML is roughly 1 in 526. Additionally, the average age at diagnosis is approximately 64 years, with nearly half of all cases occurring in individuals aged 65 and older. CML predominantly affects adults and is considered rare in children.

However, the chronic nature of CML and other myeloproliferative neoplasms requires ongoing treatment and monitoring, thereby increasing the uptake of targeted therapies. The rarity of these disorders in younger individuals shifts the focus to adult and geriatric care, which is supported by advancements in diagnostic capabilities and treatment protocols.

Moreover, product launches by major pharmaceutical players are further accelerating the growth of the myeloproliferative disorder treatment market in North America, where the prevalence of these conditions continues to rise. A notable example is the approval of Ojjaara (momelotinib) by the U.S. Food and Drug Administration (FDA) in September 2023. Developed by GSK plc, Ojjaara is approved for the treatment of adults with intermediate- or high-risk myelofibrosis, including primary myelofibrosis and secondary myelofibrosis (resulting from post-polycythemia vera or post-essential thrombocythemia), particularly in patients with anemia. Ojjaara is a once-daily oral JAK1/JAK2 and activin A receptor type 1 (ACVR1) inhibitor, offering a differentiated mechanism of action that addresses both the underlying disease and associated anemia.

Thus, the interplay of all the aforementioned factors is likely to fuel the regional market for the myeloproliferative disorder treatment market during the forecast period from 2025 to 2032.

Myeloproliferative Disorder Treatment Market Key Players:

Some of the key market players operating in the myeloproliferative disorder treatment market include Novartis AG, Incyte Corporation, Bristol Myers Squibb, CTI BioPharma, GSK, PharmaEssentia, Shire, Pfizer, Takeda, Teva Pharmaceuticals, Merck, and others.

Recent Developmental Activities in the Myeloproliferative Disorder Treatment Market:

• In September 2023, GSK announced that the U.S. Food and Drug Administration (FDA) approved Ojjaara (momelotinib) for the treatment of adults with intermediate or high-risk myelofibrosis, including both primary myelofibrosis and secondary forms arising from polycythaemia vera or essential thrombocythaemia, who also have anaemia.

Key takeaways from the myeloproliferative disorder treatment market report study

• Market size analysis for current myeloproliferative disorder treatment market size (2024), and market forecast for 8 years (2025 to 2032)
• Top key product/technology developments, mergers, acquisitions, partnerships, and joint ventures happened over the last 3 years.
• Key companies dominating the myeloproliferative disorder treatment market.
• Various opportunities available for the other competitors in the myeloproliferative disorder treatment market space.
• What are the top-performing segments in 2024? How these segments will perform in 2032?
• Which are the top-performing regions and countries in the current myeloproliferative disorder treatment market scenario?
• Which are the regions and countries where companies should have concentrated on opportunities for myeloproliferative disorder treatment market growth in the coming future?

Target audience who can benefit from this myeloproliferative disorder treatment market report study

• Myeloproliferative disorder treatment product providers
• Research organizations and consulting companies
• Myeloproliferative disorder treatment-related organizations, associations, forums, and other alliances
• Government and corporate offices
• Start-up companies, venture capitalists, and private equity firms
• Distributors and traders dealing in myeloproliferative disorder treatment
• Various end-users who want to know more about the myeloproliferative disorder treatment market and the latest technological developments in the myeloproliferative disorder treatment market

Frequently Asked Questions for the Myeloproliferative Disorder Treatment Market:

1. What is myeloproliferative disorder treatment?

• Myeloproliferative Disorders (MPDs), more commonly referred to as Myeloproliferative Neoplasms (MPNs), are a group of rare blood cancers that arise from clonal hematopoietic stem cell disorders. They are characterized by the excessive production of one or more types of mature blood cells, including red blood cells, white blood cells, or platelets in the bone marrow. This overproduction is typically driven by mutations in genes that regulate cell proliferation, such as JAK2, CALR, or MPL, leading to abnormal growth and function of blood-forming cells.

2. What is the market for myeloproliferative disorder treatment?

• The myeloproliferative disorder treatment market is estimated to grow at a CAGR of 4.91% during the forecast period from 2025 to 2032.

3. What are the drivers for the myeloproliferative disorder treatment market?

• The demand for myeloproliferative disorder (MPD) treatment is experiencing a significant surge, driven by a convergence of critical factors that highlight the market's strong growth trajectory. Foremost among these is the increasing prevalence of MPDs, fueled by an aging global population, heightened disease awareness, and improved diagnostic capabilities. Parallel to this, rapid advancements in molecular diagnostics and the development of targeted therapies have revolutionized the management of these disorders enabling earlier detection, more precise treatment regimens, and improved patient outcomes. Collectively, these trends are cultivating a highly favorable landscape for sustained innovation and investment, positioning the MPD treatment market for robust and enduring growth over the forecast period from 2025 to 2032.

4. Who are the key players operating in the myeloproliferative disorder treatment market?

• Some of the key market players operating in the myeloproliferative disorder treatment market include Novartis AG, Incyte Corporation, Bristol Myers Squibb, CTI BioPharma, GSK, PharmaEssentia, Shire, Pfizer, Takeda, Teva Pharmaceuticals, Merck, and others.

5. Which region has the highest share in the myeloproliferative disorder treatment market?

• North America is expected to hold the largest share of myeloproliferative disorder treatment during the forecast period from 2025 to 2032. This dominance is primarily attributed to the high prevalence of conditions such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), coupled with greater disease awareness among healthcare providers and patients. Additionally, increasing R&D activities and product launches by key market players further contribute to the region's strong market position.

Table of Contents

1. Myeloproliferative Disorder Treatment Market Report Introduction

• 1.1. Scope of the Study
• 1.2. Market Segmentation
• 1.3. Market Assumption

2. Myeloproliferative Disorder Treatment Market Executive Summary

• 2.1. Market at Glance

3. Competitive Landscape

4. Regulatory Analysis

• 4.1. The United States
• 4.2. Europe
• 4.3. Japan
• 4.4. China

5. Myeloproliferative Disorder Treatment Market Key Factors Analysis

• 5.1. Myeloproliferative Disorder Treatment Market Drivers
  • 5.1.1. Rising prevalence of myeloproliferative disorders
  • 5.1.2. Advancements in molecular diagnostics and targeted therapies
• 5.2. Myeloproliferative Disorder Treatment Market Restraints and Challenges
  • 5.2.1. Complications & safety concerns associated with myeloproliferative disorder drugs
  • 5.2.2. Stringent regulatory approvals
• 5.3. Myeloproliferative Disorder Treatment Market Opportunity
  • 5.3.1. Increasing research & development and clinical trials for the development of myeloproliferative disorder therapies

6. Myeloproliferative Disorder Treatment Market Porter's Five Forces Analysis

• 6.1. Bargaining Power of Suppliers
• 6.2. Bargaining Power of Consumers
• 6.3. Threat of New Entrants
• 6.4. Threat of Substitutes
• 6.5. Competitive Rivalry

7. Myeloproliferative Disorder Treatment Market Assessment

• 7.1. By Drug Class
  • 7.1.1. Inhibitors
    • 7.1.1.1. JAK Inhibitors
    • 7.1.1.2. Tyrosine Kinase Inhibitors
    • 7.1.1.3. STAMP Inhibitor
    • 7.1.1.4. Protein Synthesis Inhibitor
  • 7.1.2. Interferons
• 7.2. By Treatment Type
  • 7.2.1. Targeted Therapy
  • 7.2.2. Immunotherapy
  • 7.2.3. Chemotherapy
• 7.3. By Indication
  • 7.3.1. Chronic Myeloid Leukemia (CML)
  • 7.3.2. Polycythemia Vera (PV)
  • 7.3.3. Myelofibrosis
  • 7.3.4. Essential Thrombocythemia (ET)
• 7.4. By Route of Administration
  • 7.4.1. Oral
  • 7.4.2. Subcutaneous
• 7.5. By Distribution Channel
  • 7.5.1. Retail & Hospital Pharmacies
  • 7.5.2. Online Pharmacies
• 7.6. By Geography
  • 7.6.1. North America
    • 7.6.1.1. United States Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.1.2. Canada Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.1.3. Mexico Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
  • 7.6.2. Europe
    • 7.6.2.1. France Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.2.2. Germany Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.2.3. United Kingdom Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.2.4. Italy Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.2.5. Spain Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.2.6. Rest of Europe Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
  • 7.6.3. Asia-Pacific
    • 7.6.3.1. China Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.3.2. Japan Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.3.3. India Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.3.4. Australia Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.3.5. South Korea Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.3.6. Rest of Asia-Pacific Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
  • 7.6.4. Rest of the World (RoW)
    • 7.6.4.1. Middle East Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.4.2. Africa Myeloproliferative Disorder Treatment Market Size in USD million (2022-2032)
    • 7.6.4.3. South America Myeloproliferative Disorder Treatment Market Size In USD Million (2022-2032)

8. Myeloproliferative Disorder Treatment Market Company and Product Profiles

• 8.1. Novartis AG
  • 8.1.1. Company Overview
  • 8.1.2. Company Snapshot
  • 8.1.3. Financial Overview
  • 8.1.4. Product Listing
  • 8.1.5. Entropy
• 8.2. Incyte Corporation
  • 8.2.1. Company Overview
  • 8.2.2. Company Snapshot
  • 8.2.3. Financial Overview
  • 8.2.4. Product Listing
  • 8.2.5. Entropy
• 8.3. Bristol Myers Squibb
  • 8.3.1. Company Overview
  • 8.3.2. Company Snapshot
  • 8.3.3. Financial Overview
  • 8.3.4. Product Listing
  • 8.3.5. Entropy
• 8.4. CTI BioPharma
  • 8.4.1. Company Overview
  • 8.4.2. Company Snapshot
  • 8.4.3. Financial Overview
  • 8.4.4. Product Listing
  • 8.4.5. Entropy
• 8.5. GSK
  • 8.5.1. Company Overview
  • 8.5.2. Company Snapshot
  • 8.5.3. Financial Overview
  • 8.5.4. Product Listing
  • 8.5.5. Entropy
• 8.6. PharmaEssentia
  • 8.6.1. Company Overview
  • 8.6.2. Company Snapshot
  • 8.6.3. Financial Overview
  • 8.6.4. Product Listing
  • 8.6.5. Entropy
• 8.7. Shire
  • 8.7.1. Company Overview
  • 8.7.2. Company Snapshot
  • 8.7.3. Financial Overview
  • 8.7.4. Product Listing
  • 8.7.5. Entropy
• 8.8. Pfizer
  • 8.8.1. Company Overview
  • 8.8.2. Company Snapshot
  • 8.8.3. Financial Overview
  • 8.8.4. Product Listing
  • 8.8.5. Entropy
• 8.9. Takeda
  • 8.9.1. Company Overview
  • 8.9.2. Company Snapshot
  • 8.9.3. Financial Overview
  • 8.9.4. Product Listing
  • 8.9.5. Entropy
• 8.10. Teva Pharmaceuticals
  • 8.10.1. Company Overview
  • 8.10.2. Company Snapshot
  • 8.10.3. Financial Overview
  • 8.10.4. Product Listing
  • 8.10.5. Entropy
• 8.11. Merck
  • 8.11.1. Company Overview
  • 8.11.2. Company Snapshot
  • 8.11.3. Financial Overview
  • 8.11.4. Product Listing
  • 8.11.5. Entropy

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10. Project Approach

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