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시장보고서
상품코드
2082912
성인 근시 : 시장 인사이트, 역학 및 시장 예측(2036년)Adult Myopia - Market Insight, Epidemiology, and Market Forecast - 2036 |
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DelveInsight
성인 근시 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘 등 현재의 치료 현황에 대한 종합적인 분석을 제공합니다. 본 보고서에서는 성인 근시 환자의 부담 동향, 수익 및 시장 점유율 동향, 피크 시기의 환자 점유율 및 치료 도입률 분석을 평가함과 동시에, 세계 각 지역 시장 규모에 대한 상세한 평가 및 성장률 예측(과거 데이터 및 2022년-2036년 예측)을 제시하고 있습니다. 본 보고서에서는 성인 근시의 주요 미충족 요구 사항을 부각시키고, 경쟁 구도와 임상 환경을 분석하여 고부가가치 기회를 도출하는 한편, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.
유병률 증가
근시는 전 세계적으로 가장 흔한 안과 질환이며, 화면 사용 시간 증가와 야외 활동의 감소로 인해 그 유병률이 급격히 증가하고 있습니다. 사회경제적 지위나 생활 방식과 관련된 몇 가지 환경적 위험 요인이 확인되었으며, 이러한 요인들은 이러한 추세와 밀접한 관련이 있습니다.
인식의 제고
수년에 걸쳐 전 세계적으로 근시 유병률이 급속히 증가함에 따라, 일반 대중의 근시에 대한 인식도 높아지고 있습니다. 인식 제고는 조기 선별 검사, 예방 및 효과적인 관리를 촉진함으로써 질환의 전반적인 부담을 줄이는 데 도움이 되며, 근시 억제를 위한 공중보건 전략에서 필수적인 요소로 자리 잡고 있습니다.
승인된 치료법의 부재
현재 근시에 대해 승인된 약물 치료법은 존재하지 않으며, 이는 큰 미충족 의료 수요인 동시에 제약 기업에게는 큰 미개척 기회이기도 합니다. 성인 근시의 현재 치료 방법은 광학 기기나 외과적 시술로 한정되어 있으며, 이들 모두 고유한 한계와 과제를 안고 있습니다. 따라서 기존 치료법의 단점을 보완하고, 보다 효과적이며 이용하기 쉬운 장기적인 관리 방안을 제공할 수 있는 새로운 치료법의 개발에는 큰 여지가 있습니다.
성인 근시의 개요와 진단
근시는 주로 안축의 과도한 신장에 의해 유발되는 일반적인 굴절 이상으로, 빛이 망막 앞쪽에서 초점을 맺게 되어 먼 곳의 시야가 흐릿해지는 상태입니다. 이 상태는 보통 소아기에 발병하지만, 성인기까지 진행될 수도 있으며, 유전적 요인과 환경적 요인(장시간 근거리 작업, 화면 노출 증가, 도시화, 야외 활동 감소 등)의 영향을 모두 받습니다. 근시는 일반적으로 구면 등가 굴절 이상이 -0.5 디옵터(D) 이하인 경우로 정의되지만, 고도 근시는 망막 박리, 녹내장, 근시성 황반변성, 돌이킬 수 없는 시력 상실과 같은 심각한 안과적 합병증의 위험 증가와 관련이 있습니다. 특히 동아시아와 동남아시아에서 근시의 유병률이 전 세계적으로 증가하고 있어, 근시는 중요한 공중보건상의 우려 사항이 되고 있습니다.
성인 근시 진단
근시 진단은 주로 시력 검사, 굴절 이상 검사, 그리고 레티노스코프, 폴로프터 또는 자동 굴절 측정 장치를 이용한 굴절 측정을 포함한 안과적 평가를 바탕으로 이루어집니다. 특히 소아나 젊은 성인의 경우, 조절에 의한 간섭을 최소화하고 진단의 정확도를 높이기 위해 일반적으로 산동 굴절 검사가 시행됩니다. 또한, 고도 근시나 병적 근시, 그리고 망막 변성이나 녹내장 등 관련 안과적 합병증을 확인하기 위해 안축 길이 측정, 망막 검사, 각막 평가, 안압 측정 등의 추가 검사가 실시될 수 있습니다.
성인 근시 치료
근시 치료는 주로 굴절 이상 교정, 근시 진행 지연, 그리고 장기적인 안구 합병증 예방에 중점을 둡니다. 일반적인 관리 방법에는 안경과 콘택트렌즈가 포함되지만, 적격한 성인의 경우 라식(LASIK), PRK, SMILE, 콜라머 인공수정체(ICL) 등의 굴절 교정 수술을 통해 시력을 개선할 수도 있습니다. 진행성 근시, 특히 소아 및 젊은 성인의 경우, 저용량 아트로핀 점안액, 오르토케라톨로지, 주변부 디포커스 콘택트렌즈 등의 치료법이 안축장의 연장이나 질환의 진행을 늦추는 데 도움이 될 수 있습니다. 또한, 야외 활동을 늘리거나 장시간의 근거리 작업을 줄이는 등 생활 습관을 개선하는 것도 권장됩니다. 망막박리, 녹내장, 근시성 황반변성 등의 합병증을 조기에 발견하기 위해서는 정기적인 안과 검진이 중요합니다.
성인 근시의 역학적 분석 및 예측에 관한 주요 연구 결과
근시 치료 시장은 기존의 광학적 교정 방식에서 약리학적 및 표적 중심의 질환 수정 전략으로 전환되고 있지만, 안경, 콘택트렌즈, 오르토케라토지, 그리고 라식(LASIK)과 같은 굴절 교정 수술은 여전히 주요 표준 치료법으로 자리 잡고 있습니다. 교정 치료가 가능함에도 불구하고, 진행성 근시 및 고도 근시는 mCNV, 망막 변성, 녹내장, 시력 상실 등 돌이킬 수 없는 안과적 합병증의 심각한 위험 요인과 여전히 연관되어 있으며, 이는 충족되지 않은 의료 수요가 매우 크다는 점을 여실히 보여주고 있습니다.
현재 치료 상황에서는 안축장의 신장을 늦추고 병적인 합병증을 예방하는 것을 목적으로 한 치료법에 점점 더 초점이 맞추어지고 있습니다. 저용량 아트로핀은 근시 억제를 위한 약물 요법으로 가장 광범위하게 연구되어 왔으며, 근시 진행을 억제하는 효과가 입증되었으나, 여전히 적응증 외 사용이 지속되고 있으며, 이 적응증에 대해서는 주요 규제 당국의 승인을 아직 받지 못했습니다. 선택적 항무스카린 요법 및 차세대 약물 요법에 대한 임상적 관심이 높아짐에 따라, 향후 몇 년 동안 치료 선택지가 더욱 확대될 것으로 기대됩니다.
병적 근시 및 mCNV를 앓고 있는 환자의 경우, 라니비주맙, 아프리벨셉트, 그리고 적응증 외로 사용되는 베바시주맙과 같은 항VEGF 요법이 신생혈관 억제와 시력 기능 유지에 있어 여전히 가장 효과적인 치료 선택지로 남아 있습니다. 라니비주맙는 전 세계 여러 시장에서 황반하 mCNV에 대해 최초로 승인된 항-VEGF 치료제가 되었으나, 반면 아프리벨셉트는 VEGF에 대한 결합 친화도가 높고, 안구 내 작용 지속 시간이 더 길 가능성이 있습니다.
광학적 근시 조절 요법: 안경, 누진 다초점 렌즈, 엑제큐티브 바이포컬, 다초점/주변부 디포커스 콘택트렌즈 및 오르토케라톨로지가 포함됩니다. 현재 이용 가능한 광학적 접근법 중, 엑제큐티브 바이포컬, 오르토케라톨로지, 그리고 주변부 플러스 콘택트렌즈는 발표된 연구를 통해 근시 진행 및 안축장 연장을 임상적으로 유의미하게 억제하는 것으로 입증되었습니다. 또한, 확장 초점 심도 렌즈도 장기적인 근시 관리를 위한 유망한 대안으로 부상하고 있습니다.
시력 교정은 여전히 치료의 주축이지만, 근시 진행을 늦추기 위해 저용량 아트로핀이나 그 밖의 새로운 약물 요법과 같은 근시 진행 억제법이 적응증이 되는 증례에 사용되고 있습니다. 이와 더불어, 항-VEGF 요법은 진행된 합병증, 특히 mCNV의 관리에 있어 계속해서 핵심적인 역할을 수행하고 있습니다.
DelveInsight's 'Adult Myopia - Market Insights, Epidemiology and Market Forecast - 2036' report delivers an in-depth understanding of the Adult Myopia, historical and forecasted epidemiology, as well as the Adult Myopia market trends in the United States, EU4 (Germany, Spain, Italy, and France), and the United Kingdom, and Japan.
The Adult Myopia market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates adult myopia patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment, and growth rate projections (Historical & Forecast 2022-2036) across global regions. The report highlights key unmet medical needs in adult myopia and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.
Key Factors Driving the Adult Myopia Market
Rising Prevalence
Myopia is the most common ophthalmic condition worldwide, and its prevalence has risen rapidly due to increased screen time and reduced outdoor activity. Several environmental risk factors linked to socioeconomic status and lifestyle have been identified and are strongly associated with this trend.
Increased awareness
Over the years, public awareness of myopia has increased alongside the rapid global rise in its prevalence. Greater awareness can help reduce the overall disease burden by promoting early screening, prevention, and effective management, making it an essential component of public health strategies for myopia control.
Absence of an approved therapy
To date, there are no approved pharmacological therapies for myopia, representing a major unmet clinical need and a substantial untapped opportunity for pharmaceutical companies. The current treatment landscape for adult myopia is limited to optical devices and surgical interventions, both of which are associated with inherent limitations and challenges. This creates significant scope for the development of novel therapeutic options capable of addressing the shortcomings of existing interventions while offering more effective and accessible long-term management.
Adult Myopia Overview and Diagnosis
Myopia is a common refractive disorder primarily caused by excessive axial elongation of the eye, resulting in blurred distance vision due to light focusing in front of the retina. The condition typically develops during childhood but may progress into adulthood and is influenced by both genetic and environmental factors, including prolonged near work, increased screen exposure, urbanization, and reduced outdoor activity. Myopia is generally defined as a spherical equivalent refractive error of <= -0.5 diopters (D), while high myopia is associated with an increased risk of serious ocular complications such as retinal detachment, glaucoma, myopic macular degeneration, and irreversible vision loss. The rising global prevalence of myopia, particularly in East and Southeast Asia, has made it a significant public health concern.
Adult Myopia Diagnosis
Diagnosis of Myopia is primarily based on ophthalmic evaluation, including visual acuity assessment, refractive error testing, and refraction measurements using retinoscopy, phoropters, or automated refractive devices. Cycloplegic refraction is commonly used, particularly in children and younger adults, to improve diagnostic accuracy by minimizing accommodative interference. Additional assessments such as axial length measurement, retinal examination, corneal evaluation, and intraocular pressure testing may be performed to identify high myopia, pathologic myopia, and associated ocular complications including retinal degeneration and glaucoma.
Adult Myopia Treatment
Treatment of Myopia primarily focuses on correcting refractive error, slowing myopia progression, and preventing long-term ocular complications. Standard management includes spectacles and contact lenses, while refractive procedures such as LASIK, PRK, SMILE, and implantable collamer lenses (ICL) may be used in eligible adults to improve visual acuity. In progressive myopia, particularly in younger patients and young adults, interventions such as low-dose atropine eye drops, orthokeratology, and peripheral defocus contact lenses may help slow axial elongation and disease progression. Lifestyle modifications, including increased outdoor activity and reduction of prolonged near work, are also recommended. Regular ophthalmic monitoring is important to detect complications such as retinal detachment, glaucoma, and myopic macular degeneration.
Adult Myopia Unmet Needs
The section "unmet needs of Adult Myopia" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.
Key Findings from Adult Myopia Epidemiological Analysis and Forecast
Adult Myopia Drug Analysis & Competitive Landscape
The Adult Myopia drug chapter provides a detailed, market-focused review of the emerging pipeline across Phase I-III clinical trials. It covers the mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, and strategic partnerships for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the adult myopia treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the adult myopia therapeutics market.
Drug Class Insights
The Myopia market is evolving from conventional optical correction approaches toward pharmacological and targeted disease-modifying strategies, although spectacles, contact lenses, orthokeratology, and refractive surgeries such as LASIK continue to remain the primary standard of care. Despite available corrective interventions, progressive and high myopia remain associated with significant risks of irreversible ocular complications, including mCNV, retinal degeneration, glaucoma, and vision loss, highlighting a major unmet clinical need.
The current treatment landscape is increasingly focused on therapies aimed at slowing axial elongation and preventing pathologic complications. Low-dose atropine remains the most extensively studied pharmacological intervention for myopia control and has demonstrated efficacy in reducing myopia progression, although it continues to be used off-label and is not yet approved by major regulatory agencies for this indication. Growing clinical interest in selective antimuscarinic therapies and next-generation pharmacologic agents is expected to further expand the therapeutic landscape over the coming years.
In patients with pathologic myopia and mCNV, anti-VEGF therapies such as Ranibizumab, Aflibercept, and off-label bevacizumab remain the most effective treatment options for controlling neovascularization and preserving visual function. Ranibizumab became the first approved anti-VEGF therapy for subfoveal mCNV in several global markets, while aflibercept offers higher VEGF-binding affinity and potentially longer intraocular activity.
Drug Class/Insights into Leading Emerging and Marketed Therapies in Adult Myopia (2022-2036 Forecast)
The myopia treatment landscape spans from vision correction to long-term disease management, moving beyond simple refractive solutions toward strategies that address disease progression and prevent vision-threatening complications. While optical correction remains the foundation for restoring visual acuity, increasing focus is placed on slowing axial elongation and reducing the risk of irreversible retinal damage.
Optical control therapies: Include spectacles, progressive addition lenses, executive bifocals, multifocal/peripheral defocus contact lenses, and orthokeratology. Among currently available optical approaches, executive bifocals, orthokeratology, and peripheral plus contact lenses have demonstrated clinically meaningful reductions in myopia progression and axial elongation in published studies. Extended depth-of-focus lenses are also emerging as promising options for long-term myopia control.
Optical correction remains the mainstay of care, while myopia-control approaches such as low-dose atropine and other emerging pharmacologic options are being used in selected cases to help slow progression. Alongside this, anti-VEGF therapies continue to be central in managing advanced complications, particularly mCNV.
Adult Myopia Drug Uptake
This section focuses on the uptake rate of potential drugs expected to be launched in the market during the forecast period (2026-2036). The analysis covers the Adult Myopia drug's uptake, performance at peak, factors affecting performance during prime years of growth, patient uptake by therapy, and anticipated sales generated by each drug.
The uptake of therapies in Myopia is expected to vary across optical correction therapies, pharmacological myopia-control treatments, and advanced surgical and retinal therapies. At present, there are no approved disease-modifying pharmacological therapies for myopia, and the pipeline remains relatively limited.
Low-dose atropine is expected to see rising uptake, particularly among pediatric and young adult patients with progressive myopia. Emerging therapies, including selective antimuscarinics, 7-methylxanthine, advanced peripheral defocus lenses, and scleral strengthening procedures, are likely to gain gradual adoption as long-term efficacy and safety evidence matures. Uptake will depend on their ability to slow axial elongation, improve tolerability, minimize adverse effects, and prevent progression to high/pathologic myopia.
Detailed insights of emerging therapies' drug uptake is included in the report.
Market Access and Reimbursement of Adult Myopia
Reimbursement is a crucial factor that affects the drug's access to the market. Often, the decision to reimburse comes down to the price of the drug relative to the benefit it produces in treated patients. To reduce the healthcare burden of these high-cost therapies, many payment models are being considered by payers and other industry insiders.
NOTE: Further Details are provided in the final report....
Adult Myopia Therapies Price Scenario & Trends
Pricing and analogue assessment of Adult Myopia therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, the closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.
Further details are provided in the final report....
Industry Experts and Physician Views for Adult Myopia
To keep up with Adult Myopia market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry experts were contacted for insights on the emerging adult myopia therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns in adult myopia, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.
DelveInsight's analysts connected with 10+ KOLs to gather insights at the country level. Centers such as the Department of Ophthalmology, Keio University School of Medicine and Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz etc., were contacted. Their opinion helps understand and validate current and emerging Adult Myopia therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for market access, therapy adoption, and pipeline prioritization in adult myopia.
Qualitative Analysis: SWOT and Conjoint Analysis
We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and conjoint analysis.
In the SWOT analysis of Adult Myopia, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided.
Conjoint analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.
The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.
Market Insights