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시장보고서
상품코드
2082977
기관지확장증 : 시장 인사이트, 역학 및 예측(2036년)Bronchiectasis - Market Insight, Epidemiology, and Market Forecast - 2036 |
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DelveInsight
기관지확장증 시장 규모 및 전망
본 기관지확장증 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘을 포함하여 현재 시장 상황에 대한 종합적인 분석을 제공합니다. 기관지확장증 환자의 부담 동향, 수익 및 시장 점유율 동향, 피크 시 환자 점유율 및 치료법 보급 현황에 대한 분석을 평가하고, 주요 7개 국가 및 지역 전체에 걸친 상세한 시장 규모 평가와 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제공합니다. 본 보고서는 기관지확장증 분야에서 주요 미충족 의료 수요를 부각시키고, 경쟁 구도와 임상 상황을 분석하여 고부가가치 기회를 도출함으로써, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.
북미 : 미국
유럽 : 독일, 프랑스, 이탈리아, 스페인, 영국
아시아태평양 : 일본
기관지확장증의 개요와 진단
기관지확장증은 기관지의 영구적인 확장 및 손상을 특징으로 하는 만성 폐 질환으로, 점액 배출 장애, 만성 기침 및 재발성 폐 감염을 유발합니다. 이 질환은 돌이킬 수 없는 구조적 손상을 동반하며, 염증과 감염의 악순환을 초래하여 폐 기능과 삶의 질에 영향을 미칩니다. 위험 요인으로는 폐렴이나 결핵 등 과거의 호흡기 감염증, 만성 폐질환, 낭포성 섬유증, 자가면역질환, 면역결핍 등이 있습니다.
기관지확장증의 진단에는 주로 고해상도 흉부 컴퓨터 단층촬영(HRCT)이 사용됩니다. 이는 영구적인 기관지확장증이나 기도 벽의 비후를 확인하기 위한 골드 스탠다드인 영상 진단법입니다. 진단 과정에는 상세한 병력 청취, 신체 검사, 폐기능 검사(PFT), 그리고 만성 기도 감염의 확인 및 폐기능 평가를 목적으로 하는 가래 배양 검사도 포함됩니다. 원인을 파악하고 치료 방침을 결정하기 위해, 면역글로불린 수치 측정, 자가면역 질환 선별 검사, 낭포성 섬유증이나 알레르기성 기관지폐아스페르길루스증 등의 기저 질환 평가와 같은 추가 검사가 실시되기도 합니다.
기관지확장증 치료의 현황
기관지확장증의 치료에는 약물 요법과 비약물 요법이 모두 사용되며, 증상 관리, 악화 예방 및 환자의 삶의 질 향상을 목적으로 합니다. 치료 방침은 질환의 중증도, 근본적인 원인 및 동반 질환의 유무에 따라 환자별로 개별적으로 결정됩니다. 약물 치료의 주요 목적은 기도 손상이나 폐색으로 인해 기관지확장증 환자에게 빈번하고 반복적으로 발생하는 호흡기 감염을 예방하고 관리하는 것입니다. 항생제는 치료 계획의 핵심이며, 기도에 자주 정착하는 녹농균(Pseudomonas aeruginosa) 등의 병원체를 표적으로 하기 때문에 토브라마이신이나 아즈트레오남과 같은 흡입용 항생제가 일반적으로 처방됩니다.
흡입 요법은 폐를 직접 표적으로 삼아 작용하며, 전신성 부작용을 최소화할 수 있기 때문에 전신 항생제보다 우선적으로 사용됩니다. 그러나 감염증이 재발하기 쉬운 특성상, 장기간 또는 간헐적인 항생제 치료가 필요한 경우가 많습니다. 중증 사례나 급성 악화 시에는 감염증을 보다 효과적으로 관리하기 위해 전신 항생제가 사용되기도 합니다.
기관지확장증의 역학 분석 및 예측에 관한 주요 조사 결과
기관지확장증 시장 전망은 이 질환에 대한 인식 제고, 진단 능력 향상, 그리고 효과적인 장기 치료법에 대한 막대한 미충족 수요에 힘입어 계속해서 밝습니다. 기도 개통법, 항생제, 항염증 치료를 포함한 현재의 관리 전략은 주로 증상 조절과 악화 완화에 중점을 두고 있습니다. 그러나 근본적인 염증 경로, 만성 감염증 및 점액 기능 장애를 표적으로 하는 새로운 치료법 파이프라인이 확대되고 있어, 치료 방식에 획기적인 변화를 가져올 것으로 기대되고 있습니다. 정밀 의학의 지속적인 발전, 의료진의 인식 제고, 그리고 연구 활동의 확대에 힘입어 환자 예후가 개선되고 질병 부담이 경감되며, 성인 및 소아 환자층 모두에서 시장 성장이 촉진될 것으로 예측됩니다.
현재의 치료법을 형성하고 있는 주요 일반의약품
기타
전반적으로, 기관지확장증 분야에서는 새로 출시된 바이오의약품, 자가항체 검사(예 : 항-AChR 항체)를 통한 진단 정확도 향상, 그리고 질환에 대한 인지도 제고가 2022년부터 2036년에 걸쳐 주요 7개국 규모의 기관지확장증 시장에서 꾸준한 성장을 견인할 것으로 예상되며, 이미 출시된 제품과 개발 중인 파이프라인 모두에 큰 상업적 영향을 미칠 것으로 전망됩니다.
Bronchiectasis Market size and forecast
DelveInsight's 'Bronchiectasis - Market Insights, Epidemiology and Market Forecast - 2036' report delivers an in-depth understanding of Bronchiectasis, historical and forecasted epidemiology, as well as the bronchiectasis market trends in the United States, EU4 (Germany, Spain, Italy, and France), the United Kingdom, and Japan.
The Bronchiectasis market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, Bronchiectasis patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment, and growth rate projections (Historical & Forecast 2022-2036) across the 7MM regions. The report highlights key unmet medical needs in bronchiectasis and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.
North America: The United States
Europe: Germany, France, Italy, Spain and the United Kingdom
Asia-Pacific: Japan
Bronchiectasis Overview and Diagnosis
Bronchiectasis is a chronic lung disease characterized by permanent dilation and damage of the bronchial tubes, leading to impaired mucus clearance, chronic cough, and recurrent lung infections. The condition involves irreversible structural damage, creating a cycle of inflammation and infection that affects lung function and quality of life. Risk factors include prior respiratory infections such as pneumonia and tuberculosis, chronic lung diseases, cystic fibrosis, autoimmune disorders, immune deficiencies, among others.
Bronchiectasis is primarily diagnosed using high-resolution computed tomography (HRCT) of the chest, which is the gold-standard imaging technique for identifying permanent bronchial dilatation and airway wall thickening. The diagnostic workup also includes a detailed clinical history, physical examination, pulmonary function tests (PFTs), and sputum culture to assess lung function and detect chronic airway infections. Additional laboratory tests, such as immunoglobulin levels, autoimmune screening, and evaluation for underlying conditions like cystic fibrosis or allergic bronchopulmonary aspergillosis, may be performed to determine the cause and guide management.
Bronchiectasis Treatment Landscape
Bronchiectasis treatment involves both pharmacological and non-pharmacological interventions, with the goal of managing symptoms, preventing exacerbations, and improving the quality of life for affected individuals. The treatment approach is highly individualized, depending on the severity of the disease, the underlying cause, and the presence of any comorbid conditions. The primary goal of pharmacological treatment is to prevent and control respiratory infections, which are common and recurrent in patients with bronchiectasis due to the damaged and obstructed airways. Antibiotics are central to the treatment regimen, with inhaled antibiotics like tobramycin and aztreonam commonly prescribed to target pathogens such as Pseudomonas aeruginosa that frequently colonize the airways.
Inhaled therapies are preferred over systemic antibiotics because they deliver targeted action directly to the lungs, minimizing systemic side effects. However, due to the recurrent nature of infections, long-term or intermittent antibiotic therapy is often required. In severe cases or during acute exacerbations, systemic antibiotics may be used to manage infection more effectively.
Bronchiectasis Unmet Needs
The section "unmet needs of Bronchiectasis" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.
Key Findings from Bronchiectasis Epidemiological Analysis and Forecast
Bronchiectasis Drug Analysis & Competitive Landscape
The Bronchiectasis drug chapter provides a detailed, market-focused review of approved therapies and the emerging pipeline across mid and late Phase clinical trials. It covers mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, strategic partnerships upcoming Key catalyst for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the Bronchiectasis treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the Bronchiectasis therapeutics market.
Approved Therapies for Bronchiectasis
Brensocatib (BRINSUPRI): Astra Zeneca/ Insmed
BRINSUPRI is a dipeptidyl peptidase 1 (DPP1) inhibitor indicated for the treatment of NCFB in adult and pediatric patients 12 years of age and older. Brensocatib is a competitive, reversible inhibitor of DPP1. DPP1 activates pro-inflammatory neutrophil serine proteases (NSPs) during neutrophil maturation in the bone marrow. Activated NSPs are implicated in the pathogenesis of neutrophil-mediated NCFB inflammation.
Bronchiectasis Pipeline Analysis
Verducatib (BI 1291583): Boehringer Ingelheim
It is a novel DPP1 / cathepsin C (CatC) inhibitor with the potential to improve symptoms and quality of life for patients with bronchiectasis. Inhibition of DPP1 can reduce the level of neutrophilic inflammation that plays a key role in the pathogenesis of bronchiectasis. This may allow verducatib to prevent airway destruction, improve pathogen clearance, restore mucus composition, and reduce aberrant lung inflammation. Verducatib received FDA breakthrough therapy designation in 2024.
In July 2025, Boehringer Ingelheim reported that they launched a Phase III trial for verducatib (BI 1291583) to evaluate its potential in treating bronchiectasis.
Bronchiectasis Key Players, Market Leaders and Emerging Companies
Bronchiectasis Drug Updates
The market outlook for Bronchiectasis remains positive, driven by increasing disease awareness, improved diagnostic capabilities, and a substantial unmet need for effective long-term therapies. Current management strategies, including airway clearance techniques, antibiotics, and anti-inflammatory treatments, primarily focus on symptom control and reducing exacerbations. However, a growing pipeline of novel therapies targeting underlying inflammatory pathways, chronic infections, and mucus dysfunction is expected to transform the treatment landscape. Continued advancements in precision medicine, greater physician recognition, and expanding research efforts are anticipated to improve patient outcomes, reduce disease burden, and support market growth across both adult and pediatric populations.
Key marketed therapies shaping current management
And more
Overall, in Bronchiectasis, the launch targeted biologics, improved diagnosis through autoantibody testing (e.g., Anti-AChR), and increasing disease awareness are expected to drive steady growth in the 7MM Bronchiectasis market from 2022-2036, with strong commercial implications for both marketed products and emerging pipelines.
Drug Class/Insights into Leading Emerging and Marketed Therapies in Bronchiectasis (2022-2036 Forecast)
The treatment landscape of Bronchiectasis is rapidly evolving, with a diverse pipeline spanning DPP1/CatC inhibitors, therapeutic phage cocktails, nebulized mucoactive agents, and other novel mechanisms, collectively aiming to deliver more targeted, durable, and potentially disease-modifying outcomes beyond conventional symptom management.
Bronchiectasis Drug Uptake
Following its US launch in 2025, brensocatib is anticipated to experience a medium-to-fast market uptake, supported by its first-in-class positioning and the substantial unmet need in bronchiectasis management
Detailed insights of emerging therapies' drug uptake is included in the report.
Market Access and Reimbursement of Approved therapies in Bronchiectasis
The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of approved therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.
United State
The U.S. health care system includes both private and public health insurance coverage. Whether a drug product is covered, and at what price, is determined by each payer's coverage, coding, and payment criteria for health insurance plans. The largest government-funded programs are Medicare and Medicaid. Private plans, which cover far more Americans than public plans, have more flexibility to make coverage and reimbursement determinations.
Reimbursement is a crucial factor that affects the drug's access to the market. Often, the decision to reimburse comes down to the price of the drug relative to the benefit it produces in treated patients. To reduce the healthcare burden of these high-cost therapies, many payment models are being considered by payers and other industry insiders.
NOTE: Further Details are provided in the final report...
Bronchiectasis Therapies Price Scenario & Trends
Pricing and analogue assessment of Bronchiectasis therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.
Industry Experts and Physician Views for Bronchiectasis
To keep up with Bronchiectasis market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts were contacted for insights on the Bronchiectasis emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.DelveInsight's analysts engaged with 8+ key opinion leaders (KOLs) across major markets to capture country-level insights in Bronchiectasis Leading centers such as University of California and Royal College of Physicians, among others, were consulted to validate clinical practices, treatment patterns, and emerging therapeutic perspectives.
Their opinion helps understand and validate current and emerging Bronchiectasis, therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for Market access, therapy adoption, and pipeline prioritization in Bronchiectasis.
Qualitative Analysis: SWOT and Attribute Analysis
We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and attribute analysis.
In the SWOT analysis of Bronchiectasis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. Attribute analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.
The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.
Market Insights