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기관지확장증 : 시장 인사이트, 역학 및 예측(2036년)

Bronchiectasis - Market Insight, Epidemiology, and Market Forecast - 2036

발행일: | 리서치사: 구분자 DelveInsight | 페이지 정보: 영문 203 Pages | 배송안내 : 2-10일 (영업일 기준)

    
    
    




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기관지확장증에 대한 인사이트 및 동향

  • DelveInsight의 분석에 따르면, 주요 7개국의 기관지확장증 시장은 2025년에 약 1,600달러 규모에 달했으며, 첨단 치료법의 도입과 임상 관리의 개선이 예상에 따라 연평균 성장률(CAGR) 10%로 확대될 것으로 전망됩니다.
  • 기관지확장증의 관리는 그 진행성 및 불균일한 특성 때문에 어려움이 따릅니다. 치료는 항생제, 기도 청결법, 기관지 확장제를 이용한 감염 관리, 점액 제거 및 증상 완화에 중점을 두고 있습니다. 그러나 항생제 내성 문제와 장기적인 점액 조절을 위한 선택지가 제한적이라는 점 때문에 보다 효과적인 치료법의 필요성이 부각되고 있습니다. 흡입제나 물리치료는 보조적인 효과를 가져오지만, 표준 치료만으로는 충분하지 않은 중증 환자의 경우 외과적 개입이 필요할 수 있습니다.
  • 2025년 기준으로, 미국에서 기관지확장증 진단을 받은 환자 수는 약 44만 명에 달했습니다.
  • 브린수프리(BRINSUPRI)는 비낭포성 섬유증성 기관지확장증(NCFB) 치료제로서 최초로 FDA 승인을 획득했으며, 영국에서도 승인을 받았고, 2026년에는 일본 규제 당국의 결정이 내려질 것으로 예측됩니다.
  • 기관지확장증과 관련하여 현재 진행 중인 연구는 베링거 인겔하임의 베르두카티브(BI 1291583)나 레노비온의 ARINA-1(RVN-301) 등, 현재의 적응증 외 치료법보다 더 높은 효능을 지닌 치료법의 개발을 목표로 하고 있습니다.
  • 현재의 치료는 주로 증상 관리, 기도 청결 유지, 감염증 치료에 중점을 두고 있으나, 근본적인 기도 손상을 막거나 되돌릴 수 있는 널리 인정된 질환 수정 요법은 존재하지 않습니다. 환자는 표준 치료를 받고 있더라도 재발성 악화, 만성 세균 감염, 진행성 폐기능 저하 및 삶의 질 저하를 경험하는 경우가 많습니다.

기관지확장증 시장 규모 및 전망

  • 주요 7개국(G7)의 기관지확장증 시장 규모(2025년) : 16억 달러
  • 주요 7개국에서 기관지확장증 시장 성장률(2026-2036년) : 연평균 성장률(CAGR) 10%

본 기관지확장증 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘을 포함하여 현재 시장 상황에 대한 종합적인 분석을 제공합니다. 기관지확장증 환자의 부담 동향, 수익 및 시장 점유율 동향, 피크 시 환자 점유율 및 치료법 보급 현황에 대한 분석을 평가하고, 주요 7개 국가 및 지역 전체에 걸친 상세한 시장 규모 평가와 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제공합니다. 본 보고서는 기관지확장증 분야에서 주요 미충족 의료 수요를 부각시키고, 경쟁 구도와 임상 상황을 분석하여 고부가가치 기회를 도출함으로써, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.

대상 지역 :

북미 : 미국

유럽 : 독일, 프랑스, 이탈리아, 스페인, 영국

아시아태평양 : 일본

기관지확장증의 이해와 치료 알고리즘

기관지확장증의 개요와 진단

기관지확장증은 기관지의 영구적인 확장 및 손상을 특징으로 하는 만성 폐 질환으로, 점액 배출 장애, 만성 기침 및 재발성 폐 감염을 유발합니다. 이 질환은 돌이킬 수 없는 구조적 손상을 동반하며, 염증과 감염의 악순환을 초래하여 폐 기능과 삶의 질에 영향을 미칩니다. 위험 요인으로는 폐렴이나 결핵 등 과거의 호흡기 감염증, 만성 폐질환, 낭포성 섬유증, 자가면역질환, 면역결핍 등이 있습니다.

기관지확장증의 진단에는 주로 고해상도 흉부 컴퓨터 단층촬영(HRCT)이 사용됩니다. 이는 영구적인 기관지확장증이나 기도 벽의 비후를 확인하기 위한 골드 스탠다드인 영상 진단법입니다. 진단 과정에는 상세한 병력 청취, 신체 검사, 폐기능 검사(PFT), 그리고 만성 기도 감염의 확인 및 폐기능 평가를 목적으로 하는 가래 배양 검사도 포함됩니다. 원인을 파악하고 치료 방침을 결정하기 위해, 면역글로불린 수치 측정, 자가면역 질환 선별 검사, 낭포성 섬유증이나 알레르기성 기관지폐아스페르길루스증 등의 기저 질환 평가와 같은 추가 검사가 실시되기도 합니다.

기관지확장증 치료의 현황

기관지확장증의 치료에는 약물 요법과 비약물 요법이 모두 사용되며, 증상 관리, 악화 예방 및 환자의 삶의 질 향상을 목적으로 합니다. 치료 방침은 질환의 중증도, 근본적인 원인 및 동반 질환의 유무에 따라 환자별로 개별적으로 결정됩니다. 약물 치료의 주요 목적은 기도 손상이나 폐색으로 인해 기관지확장증 환자에게 빈번하고 반복적으로 발생하는 호흡기 감염을 예방하고 관리하는 것입니다. 항생제는 치료 계획의 핵심이며, 기도에 자주 정착하는 녹농균(Pseudomonas aeruginosa) 등의 병원체를 표적으로 하기 때문에 토브라마이신이나 아즈트레오남과 같은 흡입용 항생제가 일반적으로 처방됩니다.

흡입 요법은 폐를 직접 표적으로 삼아 작용하며, 전신성 부작용을 최소화할 수 있기 때문에 전신 항생제보다 우선적으로 사용됩니다. 그러나 감염증이 재발하기 쉬운 특성상, 장기간 또는 간헐적인 항생제 치료가 필요한 경우가 많습니다. 중증 사례나 급성 악화 시에는 감염증을 보다 효과적으로 관리하기 위해 전신 항생제가 사용되기도 합니다.

기관지확장증의 역학

기관지확장증의 역학 분석 및 예측에 관한 주요 조사 결과

  • 2025년 시점에서 주요 7개국에서 비낭성 낭성 폐질환(NCFB)으로 진단받은 환자 총수는 약 110만 건으로 추정되며, 이는 NCFB가 초래하는 막대한 부담과 지역별 진단 관행의 차이를 반영하고 있습니다.
  • 주요 7개국에서 CFB의 성별별 확진 환자 수는 2025년 시점에서 남성이 약 4만 2,000명, 여성이 약 3만 8,000명으로 추정되며, 이는 CF 환자 인구에서 관찰되는 성별 분포와 대체로 일치합니다.
  • 2025년 시점에서 주요 7개국 내 CFB 환자 중 미생물학적 검사를 통해 진단된 녹농균(Pseudomonas aeruginosa) 유병 사례 수는 약 2만 1,500건으로 추정됩니다.

기관지확장증 시장 전망

기관지확장증 시장 전망은 이 질환에 대한 인식 제고, 진단 능력 향상, 그리고 효과적인 장기 치료법에 대한 막대한 미충족 수요에 힘입어 계속해서 밝습니다. 기도 개통법, 항생제, 항염증 치료를 포함한 현재의 관리 전략은 주로 증상 조절과 악화 완화에 중점을 두고 있습니다. 그러나 근본적인 염증 경로, 만성 감염증 및 점액 기능 장애를 표적으로 하는 새로운 치료법 파이프라인이 확대되고 있어, 치료 방식에 획기적인 변화를 가져올 것으로 기대되고 있습니다. 정밀 의학의 지속적인 발전, 의료진의 인식 제고, 그리고 연구 활동의 확대에 힘입어 환자 예후가 개선되고 질병 부담이 경감되며, 성인 및 소아 환자층 모두에서 시장 성장이 촉진될 것으로 예측됩니다.

현재의 치료법을 형성하고 있는 주요 일반의약품

  • BRINSUPRI는 성인 및 12세 이상의 소아 환자에서 비화농성 낭포성 섬유증(NCFB) 치료에 사용되는 디펩티딜펩티다제 1(DPP1) 억제제입니다. 브렌소카티브는 DPP-1의 경쟁적이며 가역적인 억제제입니다. DPP1은 골수 내 호중구의 성숙 과정에서 염증 유발성 호중구 세린 프로테아제(NSP)를 활성화합니다. 활성화된 NSP는 호중구를 매개로 하는 NCFB의 염증 병태 형성에 관여하는 것으로 여겨집니다.

기타

전반적으로, 기관지확장증 분야에서는 새로 출시된 바이오의약품, 자가항체 검사(예 : 항-AChR 항체)를 통한 진단 정확도 향상, 그리고 질환에 대한 인지도 제고가 2022년부터 2036년에 걸쳐 주요 7개국 규모의 기관지확장증 시장에서 꾸준한 성장을 견인할 것으로 예상되며, 이미 출시된 제품과 개발 중인 파이프라인 모두에 큰 상업적 영향을 미칠 것으로 전망됩니다.

  • 주요 7개국 중 미국은 기관지확장증 시장에서 가장 큰 시장 규모를 차지하고 있으며, 2025년에는 약 8억 달러에 달할 것으로 평가됩니다. 이는 선진적인 의료 인프라와 높은 치료 보급률에 힘입어 이 나라가 차지하고 있는 지배적인 위상을 반영한 것입니다.
  • EU4 국가 중에서는 2025년에 영국이 약 3억 달러로 가장 큰 시장 규모를 차지한 반면, 프랑스는 같은 해 약 6,000만 달러로 가장 작은 시장 규모를 기록했습니다.
  • 치료용 파지 칵테일 : 이 접근법에서는 기관지확장증의 악화에 관여하는 특정 병원체를 선택적으로 표적으로 삼기 위해 박테리오파지를 사용합니다. AP-PA02는 서로 다른 과 및 아과에 속하는 천연 녹농균(P. aeruginosa) 표적 파지 칵테일로 구성되어 있으며, 광범위한 숙주 범위와 높은 효능을 통해 NCFB 환자의 만성 폐감염을 치료하도록 설계되었습니다. 이를 통해 표적 외 효과의 위험을 줄인 정밀한 항균 전략을 제공합니다.

자주 묻는 질문

  • 기관지확장증 시장 규모는 어떻게 되며, 향후 성장률은 어떻게 예측되나요?
  • 기관지확장증 환자의 진단 현황은 어떤가요?
  • 기관지확장증 치료에 사용되는 주요 약물은 무엇인가요?
  • 기관지확장증의 치료 현황은 어떤가요?
  • 기관지확장증의 역학에 대한 주요 조사 결과는 무엇인가요?
  • 기관지확장증 시장의 향후 전망은 어떻게 되나요?

목차

제1장 주요 인사이트

제2장 서론

제3장 기관지확장증 : 시장 개요

제4장 주요 요약

제5장 주요 이벤트

제6장 기관지확장증 : 질환 배경 및 개요

제7장 역학 및 시장 조사 방법

제8장 역학 및 환자 인구

제9장 기관지확장증 : 환자 경과

제10장 시판 치료제

제11장 단계적 치료 : 기관지확장증

제12장 기관지확장증 : 주요 7개국 시장 분석

제13장 KOL(Key Opinion Leader)의 견해

제14장 미충족 수요

제15장 SWOT 분석

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KTH 26.07.24

Bronchiectasis Insights and Trends

  • According to DelveInsight's analysis, the Bronchiectasis market across the 7MM was valued at approximately USD 1,600 in 2025 and is projected to expand at a Compounded Annual Growth Rate (CAGR) of 10%, reflecting steady growth driven by the anticipated entry of advanced therapies and improved clinical management.
  • Bronchiectasis management is challenging due to its progressive and heterogeneous nature. Treatment focuses on infection control, mucus clearance, and symptom relief using antibiotics, airway clearance techniques, and bronchodilators. However, antibiotic resistance and limited long-term mucus regulation options underscore the need for more effective therapies. While inhaled medications and physical therapy provide supportive benefits, surgical intervention may be required in severe cases where standard treatments are inadequate.
  • In 2025, the United States accounted for approximately 440,000 diagnosed prevalent cases of Bronchiectasis.
  • Brensocatib (BRINSUPRI) became first FDA-approved non-cystic fibrosis bronchiectasis (NCFB) treatment, with additional UK approval and anticipated Japan regulatory decision in 2026.
  • The ongoing research on bronchiectasis aims to develop treatments with greater efficacy than current off-label therapies including Boehringer Ingelheim's Verducatib (BI 1291583) and Renovion's ARINA-1 (RVN-301), among others.
  • Current management primarily focuses on symptom control, airway clearance, and treatment of infections, but there are no widely approved disease-modifying therapies that can halt or reverse the underlying airway damage. Patients often experience recurrent exacerbations, chronic bacterial infections, progressive lung function decline, and reduced quality of life despite standard care.

Bronchiectasis Market size and forecast

  • 2025 Bronchiectasis Market Size in the 7MM: USD 1600 million
  • Bronchiectasis Growth Rate (2026-2036) in the 7MM: 10% CAGR

DelveInsight's 'Bronchiectasis - Market Insights, Epidemiology and Market Forecast - 2036' report delivers an in-depth understanding of Bronchiectasis, historical and forecasted epidemiology, as well as the bronchiectasis market trends in the United States, EU4 (Germany, Spain, Italy, and France), the United Kingdom, and Japan.

The Bronchiectasis market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, Bronchiectasis patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment, and growth rate projections (Historical & Forecast 2022-2036) across the 7MM regions. The report highlights key unmet medical needs in bronchiectasis and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.

Geography Covered:

North America: The United States

Europe: Germany, France, Italy, Spain and the United Kingdom

Asia-Pacific: Japan

Bronchiectasis Understanding and Treatment Algorithm

Bronchiectasis Overview and Diagnosis

Bronchiectasis is a chronic lung disease characterized by permanent dilation and damage of the bronchial tubes, leading to impaired mucus clearance, chronic cough, and recurrent lung infections. The condition involves irreversible structural damage, creating a cycle of inflammation and infection that affects lung function and quality of life. Risk factors include prior respiratory infections such as pneumonia and tuberculosis, chronic lung diseases, cystic fibrosis, autoimmune disorders, immune deficiencies, among others.

Bronchiectasis is primarily diagnosed using high-resolution computed tomography (HRCT) of the chest, which is the gold-standard imaging technique for identifying permanent bronchial dilatation and airway wall thickening. The diagnostic workup also includes a detailed clinical history, physical examination, pulmonary function tests (PFTs), and sputum culture to assess lung function and detect chronic airway infections. Additional laboratory tests, such as immunoglobulin levels, autoimmune screening, and evaluation for underlying conditions like cystic fibrosis or allergic bronchopulmonary aspergillosis, may be performed to determine the cause and guide management.

Bronchiectasis Treatment Landscape

Bronchiectasis treatment involves both pharmacological and non-pharmacological interventions, with the goal of managing symptoms, preventing exacerbations, and improving the quality of life for affected individuals. The treatment approach is highly individualized, depending on the severity of the disease, the underlying cause, and the presence of any comorbid conditions. The primary goal of pharmacological treatment is to prevent and control respiratory infections, which are common and recurrent in patients with bronchiectasis due to the damaged and obstructed airways. Antibiotics are central to the treatment regimen, with inhaled antibiotics like tobramycin and aztreonam commonly prescribed to target pathogens such as Pseudomonas aeruginosa that frequently colonize the airways.

Inhaled therapies are preferred over systemic antibiotics because they deliver targeted action directly to the lungs, minimizing systemic side effects. However, due to the recurrent nature of infections, long-term or intermittent antibiotic therapy is often required. In severe cases or during acute exacerbations, systemic antibiotics may be used to manage infection more effectively.

Bronchiectasis Unmet Needs

The section "unmet needs of Bronchiectasis" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.

1. Bronchiectasis is often diagnosed late, allowing disease progression before treatment begins.

2. Recurrent exacerbations and chronic infections remain common despite current therapies.

3. There are no established disease-modifying treatments available.

4. Lack of reliable biomarkers limits patient stratification and prediction of outcomes.

5. Symptoms like cough and sputum production continue to impact quality of life.

Bronchiectasis Epidemiology

Key Findings from Bronchiectasis Epidemiological Analysis and Forecast

  • As of 2025, the total diagnosed prevalent cases of NCFB across the 7MM is estimated at approximately 1,100,000 cases, reflecting the substantial burden of NCFB and the variability in diagnostic practices across geographies.
  • The gender-specific diagnosed prevalent cases of CFB across the 7MM were estimated at approximately 42,000 cases in males and 38,000 cases in females in 2025, consistent with the broadly comparable gender distribution observed in CF populations.
  • In 2025, the microbiology-specific diagnosed prevalent cases of Pseudomonas aeruginosa in CFB patients across the 7MM were estimated at approximately 21,500 cases.

Bronchiectasis Drug Analysis & Competitive Landscape

The Bronchiectasis drug chapter provides a detailed, market-focused review of approved therapies and the emerging pipeline across mid and late Phase clinical trials. It covers mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, strategic partnerships upcoming Key catalyst for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the Bronchiectasis treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the Bronchiectasis therapeutics market.

Approved Therapies for Bronchiectasis

Brensocatib (BRINSUPRI): Astra Zeneca/ Insmed

BRINSUPRI is a dipeptidyl peptidase 1 (DPP1) inhibitor indicated for the treatment of NCFB in adult and pediatric patients 12 years of age and older. Brensocatib is a competitive, reversible inhibitor of DPP1. DPP1 activates pro-inflammatory neutrophil serine proteases (NSPs) during neutrophil maturation in the bone marrow. Activated NSPs are implicated in the pathogenesis of neutrophil-mediated NCFB inflammation.

  • In February 2026, the Medicines and Healthcare products Regulatory Agency (MHRA) granted marketing authorization in the UK for BRINSUPRI (brensocatib 25 mg tablets) for the treatment of NCFB in patients 12 years of age and older with two or more flare-ups or worsening of symptoms in the past 12 months.
  • Insmed also reported that it anticipates a regulatory decision for brensocatib for the treatment of NCFB in Japan in 2026.
  • In August 2025, the US Food and Drug Administration approved BRINSUPRI for NCFB. It is the first and only FDA-approved treatment for NCFB.

Bronchiectasis Pipeline Analysis

Verducatib (BI 1291583): Boehringer Ingelheim

It is a novel DPP1 / cathepsin C (CatC) inhibitor with the potential to improve symptoms and quality of life for patients with bronchiectasis. Inhibition of DPP1 can reduce the level of neutrophilic inflammation that plays a key role in the pathogenesis of bronchiectasis. This may allow verducatib to prevent airway destruction, improve pathogen clearance, restore mucus composition, and reduce aberrant lung inflammation. Verducatib received FDA breakthrough therapy designation in 2024.

In July 2025, Boehringer Ingelheim reported that they launched a Phase III trial for verducatib (BI 1291583) to evaluate its potential in treating bronchiectasis.

Bronchiectasis Key Players, Market Leaders and Emerging Companies

  • Astra Zeneca
  • Insmed
  • Boehringer Ingelheim
  • Armata Pharmaceuticals

Bronchiectasis Drug Updates

  • In July 2025, Boehringer Ingelheim reported the launch of a Phase III trial for Verducatib (BI 1291583) to evaluate its potential in treating bronchiectasis.
  • In December 2024, Armata Pharmaceuticals announced encouraging topline results from the completed Tailwind study a Phase II, multicenter, double-blind, randomized, placebo-controlled study evaluating the safety, phage kinetics, and efficacy of inhaled AP-PA02 in subjects with NCFB.
  • In April 2024, Renovion reported topline results from the Phase II CLIMB study of ARINA-1 (RVN-301) in individuals with NCFB, demonstrating its potential for continued development.
  • Renovion plans to further analyze the CLIMB study data, consult with regulatory authorities, and advance ARINA-1 into a Phase III program for NCFB treatment, with patient enrollment scheduled to initiate in Q3 2026.
  • Emerging preclinical therapies for bronchiectasis, including candidates from VG2D Pharma, are focused on improving mucus clearance, controlling infection, and reducing inflammation to enhance respiratory outcomes and decrease exacerbation frequency.

Bronchiectasis Market Outlook

The market outlook for Bronchiectasis remains positive, driven by increasing disease awareness, improved diagnostic capabilities, and a substantial unmet need for effective long-term therapies. Current management strategies, including airway clearance techniques, antibiotics, and anti-inflammatory treatments, primarily focus on symptom control and reducing exacerbations. However, a growing pipeline of novel therapies targeting underlying inflammatory pathways, chronic infections, and mucus dysfunction is expected to transform the treatment landscape. Continued advancements in precision medicine, greater physician recognition, and expanding research efforts are anticipated to improve patient outcomes, reduce disease burden, and support market growth across both adult and pediatric populations.

Key marketed therapies shaping current management

  • BRINSUPRI is a dipeptidyl peptidase 1 (DPP1) inhibitor indicated for the treatment of NCFB in adult and pediatric patients 12 years of age and older. Brensocatib is a competitive, reversible inhibitor of DPP1. DPP1 activates pro-inflammatory neutrophil serine proteases (NSPs) during neutrophil maturation in the bone marrow. Activated NSPs are implicated in the pathogenesis of neutrophil-mediated NCFB inflammation.

And more

Overall, in Bronchiectasis, the launch targeted biologics, improved diagnosis through autoantibody testing (e.g., Anti-AChR), and increasing disease awareness are expected to drive steady growth in the 7MM Bronchiectasis market from 2022-2036, with strong commercial implications for both marketed products and emerging pipelines.

  • Among the 7MM, the United States accounted for the largest market size of Bronchiectasis, valued at approximately USD 800 million in 2025, reflecting its dominant position driven by advanced healthcare infrastructure and higher treatment uptake.
  • Among the EU4 countries UK accounted for the largest market size at approximately USD 300 million in 2025 and France accounted for the smallest market size approximately USD 60 million in 2025.

Drug Class/Insights into Leading Emerging and Marketed Therapies in Bronchiectasis (2022-2036 Forecast)

The treatment landscape of Bronchiectasis is rapidly evolving, with a diverse pipeline spanning DPP1/CatC inhibitors, therapeutic phage cocktails, nebulized mucoactive agents, and other novel mechanisms, collectively aiming to deliver more targeted, durable, and potentially disease-modifying outcomes beyond conventional symptom management.

  • Therapeutic Phage Cocktails: This approach employs bacteriophages to selectively target specific pathogens implicated in bronchiectasis exacerbations. AP-PA02, comprising a cocktail of natural P. aeruginosa-targeting phages from distinct families and subfamilies, is designed to address chronic pulmonary infections in NCFB patients through broad host-range coverage and high potency, offering a precision antimicrobial strategy with reduced risk of off-target effects.

Bronchiectasis Drug Uptake

Following its US launch in 2025, brensocatib is anticipated to experience a medium-to-fast market uptake, supported by its first-in-class positioning and the substantial unmet need in bronchiectasis management

Detailed insights of emerging therapies' drug uptake is included in the report.

Market Access and Reimbursement of Approved therapies in Bronchiectasis

The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of approved therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

United State

The U.S. health care system includes both private and public health insurance coverage. Whether a drug product is covered, and at what price, is determined by each payer's coverage, coding, and payment criteria for health insurance plans. The largest government-funded programs are Medicare and Medicaid. Private plans, which cover far more Americans than public plans, have more flexibility to make coverage and reimbursement determinations.

Reimbursement is a crucial factor that affects the drug's access to the market. Often, the decision to reimburse comes down to the price of the drug relative to the benefit it produces in treated patients. To reduce the healthcare burden of these high-cost therapies, many payment models are being considered by payers and other industry insiders.

NOTE: Further Details are provided in the final report...

Bronchiectasis Therapies Price Scenario & Trends

Pricing and analogue assessment of Bronchiectasis therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.

Industry Experts and Physician Views for Bronchiectasis

To keep up with Bronchiectasis market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts were contacted for insights on the Bronchiectasis emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.DelveInsight's analysts engaged with 8+ key opinion leaders (KOLs) across major markets to capture country-level insights in Bronchiectasis Leading centers such as University of California and Royal College of Physicians, among others, were consulted to validate clinical practices, treatment patterns, and emerging therapeutic perspectives.

Their opinion helps understand and validate current and emerging Bronchiectasis, therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for Market access, therapy adoption, and pipeline prioritization in Bronchiectasis.

Qualitative Analysis: SWOT and Attribute Analysis

We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and attribute analysis.

In the SWOT analysis of Bronchiectasis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. Attribute analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.

The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.

Scope of the Report:

  • The report covers a segment of key events, an executive summary, a descriptive overview of Bronchiectasis, explaining their causes, signs and symptoms, pathogenesis, and currently available treatments.
  • Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression along treatment guidelines.
  • Additionally, an all-inclusive account of both the current and emerging treatments, along with the elaborative profiles of late-stage and prominent therapies, will have an impact on the current treatment landscape.
  • A detailed review of the bronchiectasis market, historical and forecasted market size, market share by therapies, detailed assumptions, and rationale behind our approach is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies by understanding trends through SWOT analysis and expert insights/KOL views, patient journey, and treatment preferences that help in shaping and driving the 7MM Bronchiectasis market.

Report Insights

  • Bronchiectasis Patient Population Forecast
  • Bronchiectasis Therapeutics Market Size
  • Bronchiectasis Pipeline Analysis
  • Bronchiectasis Market Size and Trends
  • Bronchiectasis Market Opportunity (Current and forecasted)

Report Key Strengths

  • Epidemiology-Based (Epi-based) Bottom-up Forecasting
  • Artificial Intelligence (AI)-enabled Market Research Report
  • 11-year forecast
  • Bronchiectasis Market Outlook (North America, Europe, Asia-Pacific)
  • Patient Burden Trends (by geography)
  • Bronchiectasis Treatment Addressable Market (TAM)
  • Bronchiectasis Competitive Landscape
  • Bronchiectasis Major Companies Insights
  • Bronchiectasis Price trends and Analogue Assessment
  • Bronchiectasis Therapies Drug Adoption/Uptake
  • Bronchiectasis Therapies Peak Patient Share analysis

Report Assessment

  • Bronchiectasis Current Treatment Practices
  • Bronchiectasis Unmet Needs
  • Bronchiectasis Clinical Development Analysis
  • Bronchiectasis Emerging Drugs Product Profiles
  • Bronchiectasis Market Attractiveness
  • Bronchiectasis Qualitative Analysis (SWOT and Attribute analysis)

FAQs:

Market Insights

  • What was the Bronchiectasis market size, the market size by therapies, market share (%) distribution in 2025, and what would it look like by 2036? What are the contributing factors for this growth?
  • What are the anticipated pricing variations among different geographies for the emerging therapies in the future?
  • What can be the future treatment paradigm of Bronchiectasis?
  • What are the disease risks, burdens, and unmet needs of Bronchiectasis? What will be the growth opportunities across the 7MM concerning the patient population with Bronchiectasis?
  • Who is the major future competitor in the market, and how will the competitors affect their market share?
  • What are the current options for the treatment of Bronchiectasis?
  • What are the current guidelines for treating Bronchiectasis in the US, Europe, and Japan?

Reasons to Buy:

  • The report will help in developing business strategies by understanding the latest trends and changing treatment dynamics driving the Bronchiectasis market.
  • Bottom up forecasting builds from the affected population to product forecasts, delivering a robust, data driven approach ideal for new therapies and novel classes.
  • Insights on patient burden/prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • Understand the existing market opportunities in varying geographies and the growth potential over the coming years.
  • Identifying strong upcoming players in the market will help devise strategies to help get ahead of competitors.
  • Detailed analysis and ranking of class-wise potential current and emerging therapies under the attribute analysis section to provide visibility around leading classes.
  • To understand KOLs' perspectives on the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
  • Detailed insights on the unmet needs of the existing market so that the upcoming players can strengthen their development and launch strategy.
  • This Artificial Intelligence (AI) enabled report summarize and simplify complex datasets within the report into clear, actionable insights for stakeholders, investors, and healthcare providers, enabling faster, data driven decisions.

Table of Contents

1. Key Insights

2. Report Introduction

3. Bronchiectasis Market Overview at a Glance

  • 3.1. Market Share (%) Distribution of Bronchiectasis by Therapies in the 7MM in 2025
  • 3.2. Market Share (%) Distribution of Bronchiectasis by Therapies in the 7MM in 2036

4. Executive Summary

5. Key Events

6. Disease Background and Overview: Bronchiectasis

  • 6.1. Introduction
  • 6.2. Causes and Risk Factors
  • 6.3. Clinical Types
  • 6.4. Symptoms
  • 6.5. Pathogenesis
  • 6.6. Diagnosis
    • 6.6.1. Laboratory Diagnosis
    • 6.6.2. Biomarkers
    • 6.6.3. Diagnostic Algorithm
    • 6.6.4. Diagnostic Guidelines
  • 6.7. Treatment
    • 6.7.1. Treatment Algorithm
    • 6.7.2. Treatment Guidelines

7. Epidemiology and Market Methodology

8. Epidemiology and Patient Population

  • 8.1. Key Findings on Patient Burden in Bronchiectasis
  • 8.2. Assumptions and Rationale: 7MM
    • 8.2.1. Diagnosed Prevalent Cases of NCFB
    • 8.2.3. Diagnosed Prevalent Cases of CFB
  • 8.3. Total Diagnosed Prevalent Cases of Bronchiectasis in the 7MM
  • 8.4. The United States
    • 8.4.1. Total Diagnosed Prevalent Cases of CFB in the US
    • 8.4.2. Gender-specific Diagnosed Prevalent Cases of CFB in the US
    • 8.4.3. Age-specific Diagnosed Prevalent Cases of CFB in the US
    • 8.4.4. Microbiology of CFB Patients in the US
    • 8.4.5. Total Diagnosed Prevalent Cases of NCFB in the US
    • 8.4.6. Gender-specific Diagnosed Prevalent Cases of NCFB in the US
    • 8.4.7. Severity-specific Diagnosed Prevalent Cases of NCFB in the US
    • 8.4.8. Etiology-specific Diagnosed Prevalent Cases of NCFB in the US
    • 8.4.9. Microbiology of NCFB Patients in the US
    • 8.4.10. Treated Cases of Bronchiectasis in the US
  • 8.5. EU4 and the UK
    • 8.5.1. Total Diagnosed Prevalent Cases of CFB in EU4 and the UK
    • 8.5.2. Gender-specific Diagnosed Prevalent Cases of CFB in EU4 and the UK
    • 8.5.3. Age-specific Diagnosed Prevalent Cases of CFB in EU4 and the UK
    • 8.5.4. Microbiology of CFB Patients in EU4 and the UK
    • 8.5.5. Total Diagnosed Prevalent Cases of NCFB in EU4 and the UK
    • 8.5.6. Gender-specific Diagnosed Prevalent Cases of NCFB in EU4 and the UK
    • 8.5.7. Severity-specific Diagnosed Prevalent Cases of NCFB in EU4 and the UK
    • 8.5.8. Etiology-specific Diagnosed Prevalent Cases of NCFB in EU4 and the UK
    • 8.5.9. Microbiology of NCFB Patients in EU4 and the UK
    • 8.5.10. Treated Cases of Bronchiectasis in EU4 and the UK
  • 8.6. Japan
    • 8.6.1. Total Diagnosed Prevalent Cases of CFB in Japan
    • 8.6.2. Gender-specific Diagnosed Prevalent Cases of CFB in Japan
    • 8.6.3. Age-specific Diagnosed Prevalent Cases of CFB in Japan
    • 8.6.4. Microbiology of CFB Patients in Japan
    • 8.6.5. Total Diagnosed Prevalent Cases of NCFB in Japan
    • 8.6.6. Gender-specific Diagnosed Prevalent Cases of NCFB in Japan
    • 8.6.7. Severity-specific Diagnosed Prevalent Cases of NCFB in Japan
    • 8.6.8. Etiology-specific Diagnosed Prevalent Cases of NCFB in Japan
    • 8.6.9. Microbiology of NCFB Patients in Japan
    • 8.6.10. Treated Cases of Bronchiectasis in Japan

9. Patient Journey: Bronchiectasis

10. Marketed Therapies

  • 10.1. BRINSUPRI:Astra Zeneca/Insmed
    • 10.1.1. Product Description
    • 10.1.2. Regulatory Milestones
    • 10.1.3. Other Developmental Activities
    • 10.1.4. Clinical Trials Information
    • 10.1.5. Safety and Efficacy

11. Pipeline Therapies: Bronchiectasis

  • 11.1. Competitive Landscape: Emerging Drugs
  • 11.2. Verducatib (BI 1291583): Boehringer Ingelheim
    • 11.2.1. Drug Description
    • 11.2.2. Other Developmental Activities
    • 11.2.3. Clinical Trials Information
    • 11.2.4. Safety and Efficacy
    • 11.2.5. Analysts' Views
  • 11.3. AP-PA02: Armata Pharmaceuticals
    • 11.3.1. Drug Description
    • 11.3.2. Other Developmental Activities
    • 11.3.3. Clinical Trials Information
    • 11.3.4. Safety and Efficacy
    • 11.3.5. Analysts' Views
  • 11.4. ARINA-1 (RVN-301): Renovion
    • 11.4.1. Drug Description
    • 11.4.2. Other Developmental Activities
    • 11.4.3. Clinical Trials Information
    • 11.4.4. Safety and Efficacy
    • 11.4.5. Analysts' Views

12. Bronchiectasis: 7MM Market Analysis

  • 12.1. Bronchiectasis Market Key Findings and Insights
  • 12.2. Key Market Forecast Assumptions
    • 12.2.1. Cost Assumptions and Rebates
    • 12.2.2. Pricing Trends
    • 12.2.3. Analogue Assessment
    • 12.2.4. Launch Year and Therapy Uptake
  • 12.3. Market Outlook
  • 12.4. Attribute Analysis
  • 12.5. Total Market Size of Bronchiectasis in the 7MM
  • 12.6. Market Size of Bronchiectasis by Therapies in the 7MM
  • 12.7. Market Size of Bronchiectasis in the United States
    • 12.7.1. Total Market Size of Bronchiectasis
    • 12.7.2. Market Size of Bronchiectasis by Therapies in the United States
  • 12.8. Market Size of Bronchiectasis in EU4 and the UK
    • 12.8.1. Total Market Size of Bronchiectasis
    • 12.8.2. Market Size of Bronchiectasis by Therapies in EU4 and the UK
  • 12.9. Market Size of Bronchiectasis in Japan
    • 12.9.1. Total Market Size of Bronchiectasis
    • 12.9.2. Market Size of Bronchiectasis by Therapies in Japan

13. Key Opinion Leaders' Views

14. Unmet Needs

15. SWOT Analysis

16. Market Access and Reimbursement

  • 16.1. The United States
    • 16.1.1. CMS
  • 16.2. In EU4 and the UK
    • 16.2.1. Germany
    • 16.2.2. France
    • 16.2.3. Italy
    • 16.2.4. Spain
    • 16.2.5. The United Kingdom
  • 16.3. Japan
    • 16.3.1. MHLW

17. Appendix

  • 17.1. Bibliography
  • 17.2. Report Methodology

18. DelveInsight Capabilities

19. Disclaimer

20. About DelveInsight

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