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KOL Insight - Colorectal Cancer

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ÀÌ º¸°í¼­´Â Ç¥ÀûÄ¡·á, ¸é¿ªÄ¡·á, Á¤¹ÐÀÇ·áÀÇ ÅëÇÕ¿¡ ÃÊÁ¡À» ¸ÂÃß¾î ÁøÈ­ÇÏ´Â ´ëÀå¾Ï Ä¡·á ÇöȲÀ» »ó¼¼ÇÏ°Ô ºÐ¼®ÇÕ´Ï´Ù. ºÏ¹Ì¿Í À¯·´ÀÇ KOL(Key Opinion Leader)µéÀÇ °ßÇØ¸¦ ¹ÙÅÁÀ¸·Î ÇöÀç ÀÓ»ó °üÇà, ºÐÀÚ ÇÁ·ÎÆÄÀϸµÀÇ ¿µÇâ, HER2 ¾ïÁ¦Á¦ ¹× KRAS ¾ïÁ¦Á¦¿Í °°Àº »õ·Î¿î ¾à¹°ÀÇ Ã¤Åÿ¡ ´ëÇØ °ËÅäÇϰí ÀÖ½À´Ï´Ù.

¶ÇÇÑ À¯¸Á ÆÄÀÌÇÁ¶óÀÎ ÀǾàǰ, ÁÖ¿ä ÀÓ»ó½ÃÇè, ¾×ü»ý°Ë ¹× ctDNA¿Í °°Àº Áø´Ü ÅøÀÇ ¹ßÀüµµ °ËÅäÇÏ¿©, Á¦¾àȸ»ç Àü¹®°¡µéÀÌ mCRC °ü¸®ÀÇ »õ·Î¿î µ¿Çâ, °úÁ¦ ¹× ±âȸ¿¡ ´ëÇØ ÀÚ¼¼È÷ ÀÌÇØÇÒ ¼ö ÀÖ´Â ³»¿ëÀ¸·Î ±¸¼ºµÇ¾î ÀÖ½À´Ï´Ù.

ÁÖ¿ä Áú¹®¿¡ ´ëÇÑ ´äº¯

  • 1.´ëÀå¾Ï¿¡ ´ëÇÑ ÇöÀçÀÇ Ç¥ÀûÄ¡·áÁ¦°¡ ÀÓ»óÀÇ¿¡°Ô ¾î¶»°Ô »ç¿ëµÇ°í Àνĵǰí Àִ°¡?
  • 2.ÇâÈÄ mCRC ó¹æ µ¿Çâ¿¡ °¡Àå Å« ¿µÇâÀ» ¹ÌÄ¥ °ÍÀ¸·Î ¿¹»óµÇ´Â ¾àÁ¦ Ŭ·¡½º´Â?
  • 3.°¡Àå À¯¸Á ÆÄÀÌÇÁ¶óÀÎ Á¦Ç°°ú ±× ÀáÀçÀû ½ÃÀå ¿µÇâ·ÂÀº ¹«¾ùÀΰ¡?
  • 4.ÇâÈÄ ´ëÀå¾ÏÀÇ Ä¡·á ¹æÄ§À» ¹Ù²Ü ¼ö ÀÖ´Â ÀÓ»ó½ÃÇèÀº ¾î¶² °ÍÀΰ¡?
  • 5.ÀüÀ̼º ´ëÀå¾ÏÀÇ Áø´ÜÀº ¾î¶»°Ô ÁøÈ­ÇÒ °ÍÀ¸·Î ¿¹»óµÇ´Â°¡?
  • 6.ÀüÀ̼º ´ëÀå¾Ï Ä¡·áÀÇ ÁÖ¿ä °úÁ¦¿Í ±âȸ´Â ¹«¾ùÀΰ¡?

ÁÖ¿ä ºê·£µå

  • ABBV-400(telisotuzumab adizutecan)
  • Avastin(bevacizumab)
  • BOT/BAL(botensilimab/balstilimab)
  • Braftovi(encorafenib)
  • Cyramza(ramucirumab)
  • Enhertu(trastuzumab deruxtecan)
  • Erbitux(cetuximab)
  • Etrumadenant(Arcus Biosciences)
  • Fruzaqla(fruquintinib)
  • GDC-6036(divarasib)
  • GRANITE
  • Hetronifly/Hansizhuang(serplulimab)
  • Ivonescimab
  • Jemperli(dostarlimab)
  • Keytruda(pembrolizumab)
  • Krazati(adagrasib)
  • Lumakras(sotorasib)
  • Muzastotug
  • OncoVAX
  • Opdivo/Yervoy(nivolumab/iplimumab)
  • PRO 140(leronlimab)
  • RMC-98051/RMC-6236
  • Rybrevant(amivantamab)
  • Stivarga(regorafenib)
  • Tukysa(tucatinib)
  • Vactosertib
  • Vectibix(panitumumab)
  • XL 092(zanzalintinib)
  • Zaltrap(ziv-aflibercept)
  • Ziihera(zanidatamab)

Á¶»ç ¹æ¹ý:

Therapy Trend º¸°í¼­´Â ÁÖ¿ä Áúȯ ¿µ¿ªÀÇ ÇöÀç ¹× ¹Ì·¡ Ä¡·á ÇöȲ¿¡ ´ëÇØ ¼¼°è À¯¼öÀÇ KOL(Key Opinion Leader)°úÀÇ ½ÉÃþ ÀÎÅͺ並 ÅëÇØ ÀÛ¼ºµË´Ï´Ù. KOLÀº ¼¼°èÀûÀÎ Æò°¡, ÀÓ»óÀû Àü¹®¼º, Ä¡·á ¿µ¿ª¿¡¼­ÀÇ ¿µÇâ·Â µî ¾ö°ÝÇÑ ½É»ç ±âÁØ¿¡ µû¶ó ¾ö¼±µË´Ï´Ù. °¢ ÀÎÅͺä´Â ¸é¹ÐÇÏ°Ô ÀÛ¼ºµÈ Åä·Ð °¡À̵带 ¹ÙÅÁÀ¸·Î ÁøÇàµË´Ï´Ù. ÀÌ °¡À̵å´Â KOL°ú °øµ¿À¸·Î °³¹ßµÇ¾úÀ¸¸ç, ¾÷°è Àü¹®°¡µéÀÇ °ËÅ並 °ÅÃÄ Áú¹® ³»¿ëÀÌ Á¾ÇÕÀûÀ̰í ÇöÀç ½ÃÀå ¿ªÇп¡ ÀûÇÕÇϵµ·Ï º¸ÀåÇÕ´Ï´Ù. °¢ º¸°í¼­ ¹ßÇà ÈÄ 12°³¿ù °£ÀÇ Áö¼ÓÀûÀÎ ½ÃÀå ¸ð´ÏÅ͸µÀ» ÅëÇØ Áß¿äÇÑ ´º½º À̺¥Æ®, ½ÃÀå º¯È­, ½ÃÀå °³¹ß¿¡ ´ëÇÑ KOLÀÇ ÃֽŠÁ¤º¸¸¦ Àû½Ã¿¡ Á¦°øÇÕ´Ï´Ù.

¿ì¸® º¸°í¼­ÀÇ Æ¯Â¡Àº ´ÙÀ½°ú °°½À´Ï´Ù.

FirstWord Reports´Â Á¦¾à ºÎ¹®¿¡ ƯȭµÈ ½Å·ÚÇÒ ¼ö ÀÖ´Â ¾÷°è ¸®´õ·Î¼­ ¹ÙÀÌ¿ÀÁ¦¾à Àü¹®°¡¿Í ÀÇ»ç°áÁ¤±ÇÀÚ¸¦ À§ÇÑ »ó¼¼ÇÏ°í ½Ç¿ëÀûÀÎ ÀλçÀÌÆ®¸¦ Á¦°øÇÕ´Ï´Ù. ´ç»çÀÇ ½ÉÃþÀûÀÎ ¾÷°è Áö½ÄÀº °í°´ÀÌ »õ·Î¿î µ¿ÇâÀ» ÆÄ¾ÇÇÏ°í º¹ÀâÇÑ ¹®Á¦¸¦ È¿°úÀûÀ¸·Î ÇØ°áÇÒ ¼ö ÀÖµµ·Ï ÀûÀýÇÏ°í °¡Ä¡ ÀÖ´Â ÀλçÀÌÆ®¸¦ Á¦°øÇÒ ¼ö ÀÖµµ·Ï µµ¿ÍÁÝ´Ï´Ù. ±¤¹üÀ§ÇÑ Á¶»ç¿Í ÃÖ°í ¼öÁØÀÇ Àü¹®°¡ ¹× KOLÀÇ µ¶¸³ÀûÀÌ°í °øÁ¤ÇÑ ÀλçÀÌÆ®¸¦ ¹ÙÅÁÀ¸·Î ÇÑ ´ç»çÀÇ º¸°í¼­´Â °í°´ÀÌ ÇÊ¿ä·Î ÇÏ´Â Á¤È®¼º°ú ½Å·Ú¼ºÀ» Á¦°øÇÕ´Ï´Ù. ´Ù¸¥ °÷¿¡¼­´Â ¾òÀ» ¼ö ¾ø´Â ÀÎÅͺä¿Í µ¥ÀÌÅÍ¿¡ ´ëÇÑ µ¶Á¡Àû Á¢±Ù, Áö¼ÓÀûÀÎ ½ÃÀå ¸ð´ÏÅ͸µÀ» ÅëÇØ ½ÃÀå ¿ªÇÐÀ» Á¾ÇÕÀûÀ¸·Î ÆÄ¾ÇÇÒ ¼ö ÀÖ½À´Ï´Ù. 40°³ ÀÌ»óÀÇ ¿ªµ¿ÀûÀÎ Áúȯ ¿µ¿ªÀ» ´Ù·ç°í, KOL ÀλçÀÌÆ® ¹× Á¤·®Àû ÀÇ»ç Á¶»ç¸¦ Æ÷ÇÔÇÑ ÀÇ»ç ÀÎÅÚ¸®Àü½º ±×¸®°í ÀÇ·á ¹®Á¦, µðÁöÅÐ Çコ, ¿µ¾÷ ¹× ¸¶ÄÉÆÃ, ½ÃÀå Á¢±Ù ¹× ±âŸ ºÐ¾ßÀÇ À̽´¿¡ ´ëÇÑ ¾÷°è Àü¹®°¡µéÀÇ °ßÇØ¸¦ ´ãÀº º¸°í¼­´Â º¸´Ù ½º¸¶Æ®ÇÏ°í µ¥ÀÌÅͺ£À̽ºÀÇ ÀÇ»ç°áÁ¤À» ³»¸®°í ±Þº¯ÇÏ´Â ¾÷°è¿¡¼­ °æÀï·ÂÀ» À¯ÁöÇÒ ¼ö ÀÖµµ·Ï µµ¿ÍÁÝ´Ï´Ù.

KSA

This report offers an in-depth analysis of the evolving treatment landscape for colorectal cancer, focusing on targeted therapies, immunotherapies, and the integration of precision medicine. Drawing on perspectives from key opinion leaders in North America and Europe, it examines current clinical practices, the impact of molecular profiling, and the adoption of novel agents such as HER2 and KRAS inhibitors.

This report also reviews promising pipeline drugs, pivotal clinical trials, and advances in diagnostic tools like liquid biopsy and ctDNA, providing pharmaceutical professionals with a detailed understanding of emerging trends, challenges, and opportunities in mCRC management.

Key Questions Answered:

  • 1. How are current targeted therapies for colorectal cancer used and perceived by clinicians?
  • 2. Which drug classes are expected to most impact future prescribing trends in mCRC?
  • 3. What are the most promising pipeline products and their potential market impact?
  • 4. Which clinical trials could change future treatment practices in colorectal cancer?
  • 5. How is the diagnosis of metastatic colorectal cancer expected to evolve?
  • 6. What are the major challenges and opportunities in the mCRC treatment landscape?

Key Brands:

  • ABBV-400 (telisotuzumab adizutecan)
  • Avastin (bevacizumab)
  • BOT/BAL (botensilimab/balstilimab)
  • Braftovi (encorafenib)
  • Cyramza (ramucirumab)
  • Enhertu (trastuzumab deruxtecan)
  • Erbitux (cetuximab)
  • Etrumadenant (Arcus Biosciences)
  • Fruzaqla (fruquintinib)
  • GDC-6036 (divarasib)
  • GRANITE
  • Hetronifly/Hansizhuang (serplulimab)
  • Ivonescimab
  • Jemperli (dostarlimab)
  • Keytruda (pembrolizumab)
  • Krazati (adagrasib)
  • Lumakras (sotorasib)
  • Muzastotug
  • OncoVAX
  • Opdivo/Yervoy (nivolumab/iplimumab)
  • PRO 140 (leronlimab)
  • RMC-98051/RMC-6236
  • Rybrevant (amivantamab)
  • Stivarga (regorafenib)
  • Tukysa (tucatinib)
  • Vactosertib
  • Vectibix (panitumumab)
  • XL 092 (zanzalintinib)
  • Zaltrap (ziv-aflibercept)
  • Ziihera (zanidatamab)

Methodology:

Therapy Trend reports are developed through in-depth interviews with the world's foremost Key Opinion Leaders (KOLs) on the current and future treatment landscapes in major disease areas. KOLs are carefully selected based on strict screening criteria, including their global reputation, clinical expertise, and influence within their therapeutic area. Each interview is guided by a meticulously crafted discussion guide. These guides are developed in collaboration with KOLs and peer-reviewed by industry experts to ensure that the questions are comprehensive and pertinent to current market dynamics. Through continuous market monitoring over a 12-month period following the publication of each report, we provide timely updates from KOLs on key news events, market shifts, and clinical developments.

What makes our reports different?

FirstWord Reports, a trusted industry leader with an exclusive focus on the pharmaceutical sector, delivers in-depth, actionable insights for biopharma professionals and decision-makers. Our deep industry knowledge enables us to provide relevant and valuable insights that help you identify emerging trends and navigate complex challenges effectively. Backed by extensive research and independent, impartial insights from leading experts and KOLs, our reports deliver the accuracy and reliability you need. With exclusive access to interviews and data unavailable elsewhere, along with ongoing market monitoring, we give you a comprehensive view of market dynamics. Covering over 40 dynamic disease areas and providing physician intelligence, including KOL insights and quantitative physician surveys, as well as industry expert views on issues in medical affairs, digital health, sales & marketing, market access, and other areas, our reports empower you to make smarter, data-driven decisions and maintain a competitive edge in a fast-moving industry.

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