세계의 치과용 골이식 대체물 시장 : 규모, 점유율, 성장 및 산업 분석, 유형별, 용도별, 지역별 인사이트 및 예측(2024-2032년)

Growth Factors of dental bone graft substitutes Market

The global dental bone graft substitutes market continues to expand as dental professionals increasingly depend on biologic and synthetic materials to restore bone volume and support implant procedures. According to the latest data, the market was valued at USD 307.8 million in 2024, driven by the rising prevalence of periodontal disease, tooth loss, and dental fractures. In 2025, the market is projected to reach USD 328.1 million, supported by growing adoption of implant dentistry and availability of technologically advanced grafting materials. By 2032, the global market is expected to grow significantly to USD 529.4 million, reflecting the expanding use of regenerative biomaterials and higher procedural volumes worldwide.

Dental bone graft substitutes include allografts, synthetic materials, demineralized bone matrices, and xenografts designed to restore missing or damaged bone tissue. These substitutes mimic the structure of natural bone and promote regeneration, making them essential in procedures such as ridge augmentation, sinus lifts, and implant stabilization.

Market Overview and Regional Performance

North America dominated the market in 2024 with a 47.69% share, equivalent to USD 146.8 million, driven by a high volume of dental implant surgeries, strong patient awareness, and continuous launches of new grafting solutions. Innovative technologies, including U.S. FDA-approved 3D-printed regenerative bone grafts, continue to strengthen the region's leadership position.

Europe held the second-largest share, supported by strong R&D investments and an increasing number of strategic acquisitions. Companies such as Geistlich Pharma AG are expanding their presence through acquisitions and collaborative training programs, further enhancing product adoption.

The Asia Pacific region is expected to record the highest CAGR during the forecast period. Rapid growth is driven by increasing dental disorders, a rising geriatric population needing alveolar bone regeneration, and expanding investments by manufacturers. Japan, China, and India are emerging as key markets due to increasing procedural volumes and growing technological advancements.

Latin America and the Middle East & Africa are also experiencing growing adoption due to improving healthcare infrastructure, rising patient awareness, and expanding medical tourism.

Key Market Drivers

1. Rising Demand for Advanced Bone Graft Substitutes

The increasing global incidence of periodontal disease and tooth decay-such as 514 million children with primary decay and 2 billion adults affected by permanent decay, according to the WHO-has significantly increased the demand for bone grafting procedures. Companies continue to launch advanced, more biocompatible graft substitutes. For example, in February 2024, Geistlich Pharma AG introduced Vallos granules, a demineralized allograft designed for various dental applications.

2. Growing Use of 3D-Printed Synthetic Bone Grafts

A notable trend in the market is the rapid adoption of 3D-printed regenerative grafts, which can be customized to patient-specific anatomy. These innovations enhance bone integration and clinical outcomes. The U.S. FDA approval of Desktop Metal's CMFlex 3D-printed graft in December 2022 demonstrates the growing acceptance of advanced technologies in dentistry.

3. Strategic Acquisitions and Partnerships

The market is strengthened by collaborations aimed at expanding biomaterial portfolios and improving access to regenerative products. The 2023 Biocomposites acquisition of Artoss, and partnerships between Zimmer Biomet and RTI Surgical to support U.S. veterans, underscore how industry alliances drive product availability and clinical adoption.

Market Challenges

Despite strong growth prospects, challenges persist. Limited reimbursement coverage for grafting procedures in several countries increases out-of-pocket costs for patients, affecting adoption rates. In addition, potential risks-such as immunogenic reactions, limited osteoinductive properties, or inadequate bone formation-may restrict clinical use in some regions. Strict regulatory guidelines further slow product approvals and market penetration.

Segmentation Insights

By Product Type

In 2024, the demineralized bone matrix (DBM) segment held the largest share, driven by high demand for implant procedures requiring enhanced bone regeneration. Meanwhile, synthetic bone graft substitutes are expected to grow fastest due to their availability, cost-effectiveness, and high biocompatibility.

By Form

Granules dominated the market in 2024, favored for their surface texture that promotes osteoblast attachment and stimulates osteogenesis. Putty and block forms are expected to expand with ongoing product innovations.

By End-User

Solo practices led the market in 2024, supported by strong patient preference and the high number of independent dental clinics performing grafting procedures. DSO/group practices are anticipated to grow rapidly due to centralized procurement and expanding procedural volumes.

Conclusion

The dental bone graft substitutes market is on a strong upward trajectory-progressing from USD 307.8 million in 2024 to USD 328.1 million in 2025, and reaching USD 529.4 million by 2032. With rising dental implant adoption, increased availability of advanced materials, and accelerating technological innovation, the market will continue to advance global regenerative dentistry and improve clinical outcomes for millions of patients.

Segmentation By Product Type

• Allograft
• Synthetic Bone Graft Substitutes
• Demineralized Bone Matrix
• Xenograft

By Form

• Granules
• Putty
• Others

By End-user

• Solo Practices
• DSO/ Group Practices
• Others

By Regin

• North America (By Product Type, Form, End-user, Country)
  • U.S.
  • Canada
• Europe (By Product Type, Form, End-user, Country/ Sub-region)
  • Germany
  • U.K.
  • France
  • Spain
  • Italy
  • Scandinavia
  • Rest of Europe
• Asia Pacific (By Product Type, Form, End-user, Country/ Sub-region)
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Southeast Asia
  • Rest of Asia Pacific
• Latin America (By Product Type, Form, End-user, Country/ Sub-region)
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa (By Product Type, Form, End-user, Country/ Sub-region)
  • GCC
  • South Africa
  • Rest of Middle East and Africa

Table of Content

1. Introduction

• 1.1. Research Scope
• 1.2. Market Segmentation
• 1.3. Research Methodology
• 1.4. Definitions and Assumptions

2. Executive Summary

3. Market Dynamics

• 3.1. Market Drivers
• 3.2. Market Restraints
• 3.3. Market Opportunities
• 3.4. Market Trends

4. Key Insights

• 4.1. Prevalence of Dental Disorders, By Key Countries/ Region, 2024
• 4.2. Key Industry Developments - Mergers, Acquisitions, Partnerships, etc.
• 4.3. New Product Launches, By Key Players
• 4.4. Impact of COVID-19 on the Market

5. Global Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 5.1. Market Analysis, Insights and Forecast - By Product Type
  • 5.1.1. Allograft
  • 5.1.2. Synthetic Bone Graft Substitute
  • 5.1.3. Demineralized Bone Matrix
  • 5.1.4. Xenograft
• 5.2. Market Analysis, Insights and Forecast - By Form
  • 5.2.1. Granules
  • 5.2.2. Putty
  • 5.2.3. Others
• 5.3. Market Analysis, Insights and Forecast - By End-user
  • 5.3.1. Solo Practices
  • 5.3.2. DSO/Group Practices
  • 5.3.3. Others
• 5.4. Market Analysis, Insights and Forecast - By Region
  • 5.4.1. North America
  • 5.4.2. Europe
  • 5.4.3. Asia Pacific
  • 5.4.4. Latin America
  • 5.4.5. Middle East & Africa

6. North America Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 6.1. Market Analysis, Insights and Forecast - By Product Type
  • 6.1.1. Allograft
  • 6.1.2. Synthetic Bone Graft Substitute
  • 6.1.3. Demineralized Bone Matrix
  • 6.1.4. Xenograft
• 6.2. Market Analysis, Insights and Forecast - By Form
  • 6.2.1. Granules
  • 6.2.2. Putty
  • 6.2.3. Others
• 6.3. Market Analysis, Insights and Forecast - By End-user
  • 6.3.1. Solo Practices
  • 6.3.2. DSO/Group Practices
  • 6.3.3. Others
• 6.4. Market Analysis, Insights and Forecast - By Country
  • 6.4.1. U.S.
  • 6.4.2. Canada

7. Europe Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 7.1. Market Analysis, Insights and Forecast - By Product Type
  • 7.1.1. Allograft
  • 7.1.2. Synthetic Bone Graft Substitute
  • 7.1.3. Demineralized Bone Matrix
  • 7.1.4. Xenograft
• 7.2. Market Analysis, Insights and Forecast - By Form
  • 7.2.1. Granules
  • 7.2.2. Putty
  • 7.2.3. Others
• 7.3. Market Analysis, Insights and Forecast - By End-user
  • 7.3.1. Solo Practices
  • 7.3.2. DSO/Group Practices
  • 7.3.3. Others
• 7.4. Market Analysis, Insights and Forecast - By Country/ Sub-Region
  • 7.4.1. U.K.
  • 7.4.2. Germany
  • 7.4.3. France
  • 7.4.4. Spain
  • 7.4.5. Italy
  • 7.4.6. Scandinavia
  • 7.4.7. Rest of Europe

8. Asia Pacific Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 8.1. Market Analysis, Insights and Forecast - By Product Type
  • 8.1.1. Allograft
  • 8.1.2. Synthetic Bone Graft Substitute
  • 8.1.3. Demineralized Bone Matrix
  • 8.1.4. Xenograft
• 8.2. Market Analysis, Insights and Forecast - By Form
  • 8.2.1. Granules
  • 8.2.2. Putty
  • 8.2.3. Others
• 8.3. Market Analysis, Insights and Forecast - By End-user
  • 8.3.1. Solo Practices
  • 8.3.2. DSO/Group Practices
  • 8.3.3. Others
• 8.4. Market Analysis, Insights and Forecast - By Country/ Sub-Region
  • 8.4.1. Japan
  • 8.4.2. China
  • 8.4.3. India
  • 8.4.4. Australia
  • 8.4.5. Southeast Asia
  • 8.4.6. South Korea
  • 8.4.7. Rest of Asia Pacific

9. Latin America Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 9.1. Market Analysis, Insights and Forecast - By Product Type
  • 9.1.1. Allograft
  • 9.1.2. Synthetic Bone Graft Substitute
  • 9.1.3. Demineralized Bone Matrix
  • 9.1.4. Xenograft
• 9.2. Market Analysis, Insights and Forecast - By Form
  • 9.2.1. Granules
  • 9.2.2. Putty
  • 9.2.3. Others
• 9.3. Market Analysis, Insights and Forecast - By End-user
  • 9.3.1. Solo Practices
  • 9.3.2. DSO/Group Practices
  • 9.3.3. Others
• 9.4. Market Analysis, Insights and Forecast - By Country/ Sub-Region
  • 9.4.1. Brazil
  • 9.4.2. Mexico
  • 9.4.3. Rest of Latin America

10. Middle East & Africa Dental Bone Graft Substitutes Market Analysis, Insights and Forecast, 2019-2032

• 10.1. Market Analysis, Insights and Forecast - By Product Type
  • 10.1.1. Allograft
  • 10.1.2. Synthetic Bone Graft Substitute
  • 10.1.3. Demineralized Bone Matrix
  • 10.1.4. Xenograft
• 10.2. Market Analysis, Insights and Forecast - By Form
  • 10.2.1. Granules
  • 10.2.2. Putty
  • 10.2.3. Others
• 10.3. Market Analysis, Insights and Forecast - By End-user
  • 10.3.1. Solo Practices
  • 10.3.2. DSO/Group Practices
  • 10.3.3. Others
• 10.4. Market Analysis, Insights and Forecast - By Country/ Sub-Region
  • 10.4.1. GCC
  • 10.4.2. South Africa
  • 10.4.3. Rest of Middle East & Africa

11. Competitive Analysis

• 11.1. Global Market Share Analysis (2024)
• 11.2. Company Profiles
  • 11.2.1. ZimVie Inc.
    • 11.2.1.1. Overview
    • 11.2.1.2. Products & services
    • 11.2.1.3. SWOT Analysis
    • 11.2.1.4. Recent Developments
    • 11.2.1.5. Strategies
    • 11.2.1.6. Financials (Based on Availability)
  • 11.2.2. Institut Straumann AG
    • 11.2.2.1. Overview
    • 11.2.2.2. Products & services
    • 11.2.2.3. SWOT Analysis
    • 11.2.2.4. Recent Developments
    • 11.2.2.5. Strategies
    • 11.2.2.6. Financials (Based on Availability)
  • 11.2.3. Envista
    • 11.2.3.1. Overview
    • 11.2.3.2. Products & services
    • 11.2.3.3. SWOT Analysis
    • 11.2.3.4. Recent Developments
    • 11.2.3.5. Strategies
    • 11.2.3.6. Financials (Based on Availability)
  • 11.2.4. Dentsply Sirona.
    • 11.2.4.1. Overview
    • 11.2.4.2. Products & services
    • 11.2.4.3. SWOT Analysis
    • 11.2.4.4. Recent Developments
    • 11.2.4.5. Strategies
    • 11.2.4.6. Financials (Based on Availability)
  • 11.2.5. Henry Schein, Inc.
    • 11.2.5.1. Overview
    • 11.2.5.2. Products & services
    • 11.2.5.3. SWOT Analysis
    • 11.2.5.4. Recent Developments
    • 11.2.5.5. Strategies
    • 11.2.5.6. Financials (Based on Availability)
  • 11.2.6. Medtronic
    • 11.2.6.1. Overview
    • 11.2.6.2. Products & services
    • 11.2.6.3. SWOT Analysis
    • 11.2.6.4. Recent Developments
    • 11.2.6.5. Strategies
    • 11.2.6.6. Financials (Based on Availability)
  • 11.2.7. BioHorizons
    • 11.2.7.1. Overview
    • 11.2.7.2. Products & services
    • 11.2.7.3. SWOT Analysis
    • 11.2.7.4. Recent Developments
    • 11.2.7.5. Strategies
    • 11.2.7.6. Financials (Based on Availability)
  • 11.2.8. NovaBone (Halma)
    • 11.2.8.1. Overview
    • 11.2.8.2. Products & services
    • 11.2.8.3. SWOT Analysis
    • 11.2.8.4. Recent Developments
    • 11.2.8.5. Strategies
    • 11.2.8.6. Financials (Based on Availability)
  • 11.2.9. Geistlich Pharma AG
    • 11.2.9.1. Overview
    • 11.2.9.2. Products & services
    • 11.2.9.3. SWOT Analysis
    • 11.2.9.4. Recent Developments
    • 11.2.9.5. Strategies
    • 11.2.9.6. Financials (Based on Availability)
  • 11.2.10. botiss biomaterials GmbH
    • 11.2.10.1. Overview
    • 11.2.10.2. Products & services
    • 11.2.10.3. SWOT Analysis
    • 11.2.10.4. Recent Developments
    • 11.2.10.5. Strategies
    • 11.2.10.6. Financials (Based on Availability)
  • 11.2.11. curasan AG
    • 11.2.11.1. Overview
    • 11.2.11.2. Products & services
    • 11.2.11.3. SWOT Analysis
    • 11.2.11.4. Recent Developments
    • 11.2.11.5. Strategies
    • 11.2.11.6. Financials (Based on Availability)