Beyond CRISPR : DNA 재작성의 최근 기술 진보

Emerging Tools Reshaping the Future of Gene Editing

This study highlights advancements such as prime editing, base editing, bridge RNA, SeekRNA, and gene writing platforms, as it examines the emerging field of next-generation gene editing technologies beyond CRISPR/Cas systems. These tools are revolutionary for therapeutic development, precision medicine, and functional genomics because they provide increased editing capabilities, decreased off-target effects, and improved precision. To improve accuracy and efficiency in genome engineering, the study highlights the use of artificial intelligence (AI) and machine learning for guide RNA optimization, off-target prediction, and scalable clinical translation. The collaborative innovation ecosystem is mapped by examining key stakeholders, including academic consortia, large pharmaceutical companies, biotech start-ups, and companies that provide AI-driven editing solutions. Additionally, to evaluate commercialization readiness, global funding trends, investment patterns, and regulatory environments in North America, Europe, Asia-Pacific, and emerging regions are examined. The study highlights how disruptive tools are changing the future of genetic medicine and biotechnology by spotting growth prospects and strategic partnerships.

Table of Contents

Strategic Imperatives

• Why Is It Increasingly Difficult to Grow?
• The Strategic Imperative 8
• The Impact of the Top 3 Strategic Imperatives on the Beyond CRISPR Rewriting DNA Space
• Growth Opportunities Fuel the Growth Pipeline Engine
• Research Methodology

Growth Opportunity Analysis

• Scope of Analysis
• Segmentation

Growth Generator

• Growth Drivers
• Growth Restraints

CRISPR Technology: Mechanism, Advantages, and Limitations

• CRISPR-Clustered Regularly Interspaced Short Palindromic Repeats
• Pros and Cons of CRISPR Gene Editing

Next-Generation Gene Editing Technologies

• Prime Editing-Expanding Accuracy and Versatility in Gene Editing
• Recent Innovations in Prime Editing
• Bridge RNA-The Third Generation of Genetic Engineering
• SeekRNA-A New Pathway for Accurate Gene Editing
• Epigenome Editing
• Base Editing: Unlocking Single-Nucleotide Precision
• Recent Innovations in Base Editing
• Gene Writing-A New Blueprint for Genome Engineering
• Recent Innovations in Gene Writing

AI & Machine Learning in Gene Editing

• AI and Machine Learning AI/ML in Gene Editing
• Emerging Trends in Gene Editing and AI

Translating Gene Editing to Clinical Impact: Stakeholders and Solutions

• Stakeholders Developing Gene Editing Technologies

Funding and Collaboration Landscape

• Key Collaborations in Gene Editing Technologies-Global 2023-2025
• Snapshot of Industry Funding-Global 2023-2025
• Snapshot of Academia Funding-Global 2023-2025
• Regional Trends in Gene Editing-Developments and Adoption

Growth Opportunity Universe-Beyond CRISPR Rewriting DNA

• Growth Opportunity 1: AI-Driven Guide Design and Off-Target Prediction in Gene Editing
• Growth Opportunity 2: Next-Generation Gene Editing Tools
• Growth Opportunity 3: Large DNA Integration and Rewriting

Appendix

• TRL: Explanation

Next Steps

• Benefits and Impacts of Growth Opportunities
• Next Steps
• Legal Disclaimer