다운스트림 프로세싱 시장 규모 : 방법별, 제품별, 용도별, 최종사용자별, 예측(2023-2032년)

Downstream processing market size is expected to 10.5% CAGR from 2023 to 2032 owing to the increasing prevalence of chronic diseases, coupled with a growing aging population. According to the National Institutes of Health, by 2050, 99.5% of the population above the age of 50 years or older will have at least one chronic disease. In 2020, more than 71 million people had at least one chronic disease which is expected to reach more than 142 million by 2050.

The demand for biopharmaceutical products continues to surge with the rising adoption of monoclonal antibodies and recombinant proteins for treating these chronic diseases. This factor, along with the technological developments and innovations in downstream processing methodologies are contributing to the market growth trajectory.

The downstream processing market is divided based on technique, product, application, end-user, and region.

The solid-liquid separation segment is predicted to record 11.2% CAGR from 2023 to 2032. Techniques like centrifugation, filtration, and chromatography have gained prominence due to their ability to efficiently separate biomolecules from complex mixtures. Continuous improvements in these techniques have led to enhanced purification processes, resulting in the production of high-quality biopharmaceutical products. The integration of innovative separation technologies has reduced production costs, making these techniques increasingly viable for various downstream processing applications.

The filters segment is anticipated to observe 11.6% CAGR during 2023 and 2032 owing to the adoption of advanced filtration technologies, including microfiltration, ultrafiltration, and nanofiltration. These processes have minimized the risk of contamination. The development of high-performance filters capable of removing impurities and preserving the integrity of delicate biomolecules has become crucial in meeting stringent regulatory requirements and ensuring product safety and efficacy in the biopharmaceutical industry.

Asia Pacific downstream processing market size is expected to observe nearly 11% CAGR between 2023 and 2032, driven by factors such as increasing investments in healthcare infrastructure, a growing biopharmaceutical manufacturing sector, and rising R&D activities. Countries like China, India, and Japan are witnessing substantial advancements in biotechnology and pharmaceutical industries, leading to a surge in demand for downstream processing solutions. The presence of a large patient pool and the escalating focus on personalized medicine are further propelling the market growth in the region.

Table of Contents

Chapter 1 Methodology & Scope

• 1.1 Market definition
• 1.2 Base estimates & calculations
• 1.3 Forecast calculation
• 1.4 Covid-19 impact analysis at global level
• 1.5 Data validation
• 1.6 Data sources
  • 1.6.1 Secondary
    • 1.6.1.1 Paid sources
    • 1.6.1.2 Public sources
  • 1.6.2 Primary

Chapter 2 Executive Summary

• 2.1 Downstream processing industry 360 degree synopsis, 2018 - 2032 (USD Million)
  • 2.1.1 Business trends
  • 2.1.2 Region trends
  • 2.1.3 Technique trends
  • 2.1.4 Product trends
  • 2.1.5 Application trends
  • 2.1.6 End-user trends

Chapter 3 Downstream Processing Market Insights

• 3.1 Industry landscape, 2018 - 2032 (USD Million)
• 3.2 Industry impact forces
  • 3.2.1 Growth drivers
    • 3.2.1.1 Growing demand for biopharmaceuticals
    • 3.2.1.2 Increasing R&D expenditure in biopharmaceutical industries
    • 3.2.1.3 Increasing advancements and adoption of single use technologies
    • 3.2.1.4 Rise in the prominence of contract manufacturing organizations (CMOs)
  • 3.2.2 Industry pitfalls & challenges
    • 3.2.2.1 High cost of instruments and purification
    • 3.2.2.2 Dearth of skilled personnel
• 3.3 Growth potential analysis
  • 3.3.1 By technique
  • 3.3.2 By product
  • 3.3.3 By application
  • 3.3.4 By end-user
• 3.4 COVID-19 impact analysis
• 3.5 Regulatory landscape
• 3.6 Porter's analysis
• 3.7 PESTEL analysis

Chapter 4 Competitive Landscape, 2022

• 4.1 Introduction
• 4.2 Company matrix analysis, 2022
• 4.3 Global company market share analysis, 2022
• 4.4 Competitive positioning matrix, 2022
• 4.5 Strategic dashboard, 2022

Chapter 5 Downstream Processing Market Estimates and Forecast, By Technique (USD Million)

• 5.1 Key trends, by technique
• 5.2 Purification
  • 5.2.1 Ion exchange chromatography
  • 5.2.2 Affinity chromatography
  • 5.2.3 Gel chromatography
  • 5.2.4 Hydrophobic interaction chromatography
• 5.3 Solid-liquid separation
  • 5.3.1 Filtration
    • 5.3.1.1 Tangential flow filtration
    • 5.3.1.2 Normal flow filtration
  • 5.3.2 Centrifugation
• 5.4 Clarification/Concentration
  • 5.4.1 Evaporation
  • 5.4.2 Membrane filtration
• 5.5 Other techniques

Chapter 6 Downstream Processing Market Estimates and Forecast, By Product (USD Million)

• 6.1 Key trends, by product
• 6.2 Chromatography columns and resins
• 6.3 Filters
• 6.4 Membrane absorbers
• 6.5 Single-use products
• 6.6 Other products

Chapter 7 Downstream Processing Market Estimates and Forecast, By Application (USD Million)

• 7.1 Key trends, by application
• 7.2 Monoclonal antibody production
• 7.3 Vaccine production
• 7.4 Insulin production
• 7.5 Immunoglobulin production
• 7.6 Erythropoietin production
• 7.7 Other applications

Chapter 8 Downstream Processing Market Estimates and Forecast, By End-User (USD Million)

• 8.1 Key trends, by end-user
• 8.2 Biopharmaceutical companies
• 8.3 Contract manufacturing organizations

Chapter 9 Downstream Processing Market Estimates and Forecast, By Region (USD Million)

• 9.1 Key trends, by region
• 9.2 North America
  • 9.2.1 U.S.
  • 9.2.2 Canada
• 9.3 Europe
  • 9.3.1 Germany
  • 9.3.2 UK
  • 9.3.3 France
  • 9.3.4 Spain
  • 9.3.5 Italy
  • 9.3.6 Switzerland
  • 9.3.7 Rest of Europe
• 9.4 Asia Pacific
  • 9.4.1 China
  • 9.4.2 Japan
  • 9.4.3 India
  • 9.4.4 Australia
  • 9.4.5 South Korea
  • 9.4.6 Rest of Asia Pacific
• 9.5 Latin America
  • 9.5.1 Brazil
  • 9.5.2 Mexico
  • 9.5.3 Rest of Latin America
• 9.6 Middle East & Africa
  • 9.6.1 South Africa
  • 9.6.2 Saudi Arabia
  • 9.6.3 Rest of Middle East & Africa

Chapter 10 Company Profiles

• 10.1 Thermo Fisher Scientific Inc.
• 10.2 GE Healthcare
• 10.3 Sartorius Stedim Biotech S.A
• 10.4 Danaher Corporation
• 10.5 Merck and Co. Inc.
• 10.6 3M Company
• 10.7 Boehringer Ingelheim International GmbH
• 10.8 Lonza Group Ltd.
• 10.9 Eppendorf AG
• 10.10 Repligen Corporation