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Naltrexone And Buprenorphine Market Size, Share & Trends Analysis Report By Product, By Route of Administration (Oral, Injectable) By Application, By Distribution Channel, By Region, And Segment Forecasts, 2024 - 2030

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ksm 24.09.02

Naltrexone And Buprenorphine Market Growth & Trends:

The global naltrexone and buprenorphine market size is expected to reach USD 8.42 billion by 2030, growing at a CAGR of 12.41% from 2024 to 2030, according to a new report by Grand View Research, Inc. The market is experiencing growth primarily due to the rising incidence of substance use disorders, increasing government efforts to address the crisis, and growing awareness of treatments for opioid use disorder. These factors are anticipated to substantially boost industry expansion during the forecast period, fostering advancements and improving accessibility to addiction care solutions.

The World Drug Report 2023 highlights global trends in drug use disorders, emphasizing opioids as the primary cause of death from overdose and significant contributors to years lost due to disability and premature death. Opioid Use Disorder (OUD) affects millions worldwide, with disparities in treatment access exacerbated by the COVID-19 pandemic. Regional variations in primary drugs of abuse include opioids in Europe and Asia, cocaine in Latin America, and methamphetamine in East & Southeast Asia. Stigma and discrimination hinder treatment efforts, with less than 20% of those needing help receiving it. The report calls for international cooperation to address these complex health and societal challenges.

Furthermore, increasing government initiatives to combat the OUD crisis through multifaceted approaches are growing. In February 2024, with the approval of the SAMHSA, USD 46.6 million in supplemental Community Mental Health Services Block Grant and Substance Use Prevention, Treatment, and Recovery Services Block Grant funds have been allocated to mental health and substance use services. In addition, USD 67.5 million from U.S. Department of Treasury funds has been directed to support these efforts in Wisconsin.

Moreover, industry players are driving growth in the market through strategic initiatives, such as enhanced distribution networks, strategic partnerships with healthcare providers, and increased research and development investments. For instance, in July 2023, Titan Pharmaceuticals, Inc. and Fedson, Inc. signed an Asset Purchase Agreement, under which Titan would sell part of ProNeura assets, such as its portfolio of medications for drug addiction and other early development initiatives built on the ProNeura drug delivery technology. The company's addiction portfolio comprised implant programs for Nalmefene and Probuphine. In addition, in September 2023, Camurus AB introduced Brixadi, a weekly and monthly medication containing Brixadi, indicated to treat moderate-to-severe OUD. These efforts aim to expand treatment accessibility and efficacy, propelling advancement significantly.

Naltrexone And Buprenorphine Market Report Highlights:

  • North America accounted for the largest revenue share of 39.39% in 2023, driven by robust healthcare infrastructure, high prevalence of substance use disorder, and proactive government initiatives supporting addiction treatment.
  • Based on product, the buprenorphine segment dominated the market with a share of 70.02% in 2023 and is anticipated to witness the fastest growth at a CAGR over the forecast period. The segment growth can be attributed to the various strategies adopted by key players such as product launches, collaboration, M&A, regulatory approvals, clinical trials proving efficacy, & other factors that enhance treatment initiation rates.
  • Based on route of administration, the oral administration segment held the majority share of 55.87% in 2023. However, in buprenorphine segment, the injectable administration segment held the majority share of 65.04% in 2023.
  • Based on application, the OUD segment dominated the market with a share of 69.03% in 2023. Naltrexone is widely recognized for their efficacy in managing OUD, leading to its extensive adoption in treatment programs.
  • Based on distribution channel, the hospital pharmacies segment dominated the global market with a share of 48.26% in 2023. Growth can be attributed to their key role in administering parenteral OUD treatments, such as buprenorphine, ensuring physician-supervised care, and facilitating access to essential medications.

Table of Contents

Chapter 1. Methodology and Scope

  • 1.1. Market Segmentation & Scope
  • 1.2. Segment Definitions
    • 1.2.1. Product
    • 1.2.2. Route of Administration
    • 1.2.3. Application
    • 1.2.4. Distribution channel
    • 1.2.5. Regional scope
    • 1.2.6. Estimates and forecasts timeline
  • 1.3. Research Methodology
  • 1.4. Information Procurement
    • 1.4.1. Purchased database
    • 1.4.2. GVR's internal database
    • 1.4.3. Secondary sources
    • 1.4.4. Primary research
    • 1.4.5. Details of primary research
      • 1.4.5.1. Data for primary interviews in North America
      • 1.4.5.2. Data for primary interviews in Europe
      • 1.4.5.3. Data for primary interviews in Asia Pacific
      • 1.4.5.4. Data for primary interviews in Latin America
      • 1.4.5.5. Data for Primary interviews in MEA
  • 1.5. Information or Data Analysis
    • 1.5.1. Data analysis models
  • 1.6. Market Formulation & Validation
  • 1.7. Model Details
    • 1.7.1. Commodity flow analysis (Model 1)
    • 1.7.2. Approach 1: Commodity flow approach
    • 1.7.3. Volume price analysis (Model 2)
    • 1.7.4. Approach 2: Volume price analysis
  • 1.8. List of Secondary Sources
  • 1.9. List of Primary Sources
  • 1.10. Objectives

Chapter 2. Executive Summary

  • 2.1. Market Snapshot
  • 2.2. Product and Route of Administration Segment Snapshot
  • 2.3. Application and Distribution Channel Segment Snapshot
  • 2.4. Competitive Landscape Snapshot

Chapter 3. Naltrexone and Buprenorphine Market Variables, Trends, and Scope

  • 3.1. Naltrexone and Buprenorphine Market Lineage Outlook
    • 3.1.1. Parent Market Outlook
    • 3.1.2. Ancillary market outlook
  • 3.2. Market Dynamics
    • 3.2.1. Market Driver Analysis
      • 3.2.1.1. Growing prevalence of substance use disorders
      • 3.2.1.2. Growing government initiatives to combat the crisis
      • 3.2.1.3. Increasing awareness of opioid use disorder treatment
    • 3.2.2. Market Restraint Analysis
      • 3.2.2.1. High cost of treatment
      • 3.2.2.2. Retention and adherence challenges
  • 3.3. Naltrexone and Buprenorphine Market Analysis Tools
    • 3.3.1. Porter's Five Forces Analysis
    • 3.3.2. PESTLE Analysis
  • 3.4. Pipeline Analysis
  • 3.5. Pricing Analysis
  • 3.6. Patient and Provider Considerations in Choosing Implantable Treatments
  • 3.7. Target Population Analysis
  • 3.8. Total Addressable Market (TAM) Analysis for Naltrexone & Buprenorphine Subcutaneous Absorbable Implants

Chapter 4. Naltrexone and Buprenorphine Market Analysis, by Product, 2018 - 2030 (USD Million)

  • 4.1. Naltrexone and Buprenorphine: Product Movement Analysis
  • 4.2. Naltrexone and Buprenorphine Market Analysis, by Product Market (USD Million)
  • 4.3. Naltrexone
    • 4.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.4. Buprenorphine
    • 4.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2. BELBUCA
      • 4.4.2.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 4.4.3. Sublocade
      • 4.4.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 4.4.4. Suboxone
      • 4.4.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 4.4.5. Zubsolv
      • 4.4.5.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 4.4.6. Others
      • 4.4.6.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 5. Naltrexone and Buprenorphine Market Analysis, by Route of Administration, 2018 - 2030 (USD Million)

  • 5.1. Naltrexone and Buprenorphine: Route of Administration Movement Analysis
  • 5.2. Naltrexone and Buprenorphine Market Analysis, by Route of Administration Market (USD Million)
  • 5.3. Naltrexone
    • 5.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.3.2. Oral Administration
      • 5.3.2.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.3.3. Injectable Administration
      • 5.3.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.3.4. Implantable Administration
      • 5.3.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 5.4. Buprenorphine
    • 5.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.4.2. Oral Administration
      • 5.4.2.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.4.3. Injectable Administration
      • 5.4.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 5.4.4. Implantable Administration
      • 5.4.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 6. Naltrexone and Buprenorphine Market Analysis, by Application, 2018 - 2030 (USD Million)

  • 6.1. Naltrexone and Buprenorphine: Application Movement Analysis
  • 6.2. Naltrexone and Buprenorphine Market Analysis, by Application Market (USD Million)
  • 6.3. Naltrexone
    • 6.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 6.3.2. Opioid use disorder (OUD)
      • 6.3.2.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 6.3.2.2. Alcohol use disorder (AUD)
      • 6.3.2.3. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 6.4. Buprenorphine
    • 6.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 6.4.2. Opioid use disorder (OUD)
      • 6.4.2.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 7. Naltrexone and Buprenorphine Market Analysis, by Distribution Channel, 2018 - 2030 (USD Million)

  • 7.1. Naltrexone and Buprenorphine: Distribution Channel Movement Analysis
  • 7.2. Naltrexone and Buprenorphine Market Analysis, by Distribution Channel Market (USD Million)
  • 7.3. Hospital Pharmacies
    • 7.3.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4. Retail Pharmacies
    • 7.4.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5. Others
    • 7.5.1. Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 8. Naltrexone and Buprenorphine Market: Regional Estimates and Trend Analysis by Product, by Route of Administration, by Application, by Distribution Channel

  • 8.1. Naltrexone and Buprenorphine Market: Regional Outlook
  • 8.2. North America
    • 8.2.1. North America Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.2.2. U.S.
      • 8.2.2.1. Key Country Dynamics
      • 8.2.2.2. U.S. Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.2.2.3. Competitive/Market Scenario
      • 8.2.2.4. Regulatory Framework
      • 8.2.2.5. Reimbursement scenario
    • 8.2.3. Canada
      • 8.2.3.1. Key Country Dynamics
      • 8.2.3.2. Canada Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.2.3.3. Competitive/Market Scenario
      • 8.2.3.4. Regulatory Framework
      • 8.2.3.5. Reimbursement Scenario
    • 8.2.4. Mexico
      • 8.2.4.1. Key Country Dynamics
      • 8.2.4.2. Mexico Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.2.4.3. Competitive/Market Scenario
      • 8.2.4.4. Regulatory Framework
      • 8.2.4.5. Reimbursement Scenario
  • 8.3. Europe
    • 8.3.1. Europe Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.2. UK
      • 8.3.2.1. Key Country Dynamics
      • 8.3.2.2. UK Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.2.3. Competitive/Market Scenario
      • 8.3.2.4. Regulatory Framework
      • 8.3.2.5. Reimbursement Scenario
    • 8.3.3. Germany
      • 8.3.3.1. Key Country Dynamics
      • 8.3.3.2. Germany Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.3.3. Competitive/Market Scenario
      • 8.3.3.4. Regulatory Framework
      • 8.3.3.5. Reimbursement Scenario
    • 8.3.4. France
      • 8.3.4.1. Key Country Dynamics
      • 8.3.4.2. France Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.4.3. Competitive/Market Scenario
      • 8.3.4.4. Regulatory Framework
      • 8.3.4.5. Reimbursement Scenario
    • 8.3.5. Spain
      • 8.3.5.1. Key Country Dynamics
      • 8.3.5.2. Spain Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.5.3. Competitive/Market Scenario
      • 8.3.5.4. Regulatory Framework
      • 8.3.5.5. Reimbursement Scenario
    • 8.3.6. Italy
      • 8.3.6.1. Key Country Dynamics
      • 8.3.6.2. Italy Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.6.3. Competitive/Market Scenario
      • 8.3.6.4. Regulatory Framework
      • 8.3.6.5. Reimbursement Scenario
    • 8.3.7. Denmark
      • 8.3.7.1. Key Country Dynamics
      • 8.3.7.2. Denmark Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.7.3. Competitive/Market Scenario
      • 8.3.7.4. Regulatory Framework
      • 8.3.7.5. Reimbursement Scenario
    • 8.3.8. Sweden
      • 8.3.8.1. Key Country Dynamics
      • 8.3.8.2. Sweden Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.8.3. Competitive/Market Scenario
      • 8.3.8.4. Regulatory Framework
      • 8.3.8.5. Reimbursement Scenario
    • 8.3.9. 6.3.9 Norway
      • 8.3.9.1. Key Country Dynamics
      • 8.3.9.2. Norway Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.3.9.3. Competitive/Market Scenario
      • 8.3.9.4. Regulatory Framework
      • 8.3.9.5. Reimbursement Scenario
      • 8.3.9.6. Rest of Europe Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.4. Asia Pacific
    • 8.4.1. Asia Pacific Naltrexone and Buprenorphine Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 8.4.2. Japan
      • 8.4.2.1. Key Country Dynamics
      • 8.4.2.2. Japan Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.2.3. Competitive/Market Scenario
      • 8.4.2.4. Regulatory Framework
      • 8.4.2.5. Reimbursement Scenario
    • 8.4.3. China
      • 8.4.3.1. Key Country Dynamics
      • 8.4.3.2. China Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.3.3. Competitive/Market Scenario
      • 8.4.3.4. Regulatory Framework
      • 8.4.3.5. Reimbursement Scenario
    • 8.4.4. India
      • 8.4.4.1. Key Country Dynamics
      • 8.4.4.2. India Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.4.3. Competitive/Market Scenario
      • 8.4.4.4. Regulatory Framework
      • 8.4.4.5. Reimbursement Scenario
    • 8.4.5. Australia
      • 8.4.5.1. Key Country Dynamics
      • 8.4.5.2. Australia Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.5.3. Competitive/Market Scenario
      • 8.4.5.4. Regulatory Framework
      • 8.4.5.5. Reimbursement Scenario
    • 8.4.6. Thailand
      • 8.4.6.1. Key Country Dynamics
      • 8.4.6.2. Thailand Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.6.3. Competitive/Market Scenario
      • 8.4.6.4. Regulatory Framework
      • 8.4.6.5. Reimbursement Scenario
    • 8.4.7. South Korea
      • 8.4.7.1. Key Country Dynamics
      • 8.4.7.2. South Korea Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.4.7.3. Competitive/Market Scenario
      • 8.4.7.4. Regulatory Framework
      • 8.4.7.5. Reimbursement Scenario
      • 8.4.7.6. Rest of Asia Pacific Naltrexone and Buprenorphine Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 8.5. Latin America
    • 8.5.1. Latin America Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.5.2. Brazil
      • 8.5.2.1. Key Country Dynamics
      • 8.5.2.2. Brazil Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.5.2.3. Competitive/Market Scenario
      • 8.5.2.4. Regulatory Framework
      • 8.5.2.5. Reimbursement Scenario
    • 8.5.3. Argentina
      • 8.5.3.1. Key Country Dynamics
      • 8.5.3.2. Argentina Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.5.3.3. Competitive/Market Scenario
      • 8.5.3.4. Regulatory Framework
      • 8.5.3.5. Reimbursement Scenario
      • 8.5.3.6. Rest of Latin America Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6. 6.6 MEA
    • 8.6.1. MEA Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.6.2. South Africa
      • 8.6.2.1. Key Country Dynamics
      • 8.6.2.2. South Africa Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.6.2.3. Competitive/Market Scenario
      • 8.6.2.4. Regulatory Framework
      • 8.6.2.5. Reimbursement Scenario
    • 8.6.3. Saudi Arabia
      • 8.6.3.1. Key Country Dynamics
      • 8.6.3.2. Saudi Arabia Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.6.3.3. Competitive/Market Scenario
      • 8.6.3.4. Regulatory Framework
      • 8.6.3.5. Reimbursement Scenario
    • 8.6.4. UAE
      • 8.6.4.1. Key Country Dynamics
      • 8.6.4.2. UAE Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.6.4.3. Competitive/Market Scenario
      • 8.6.4.4. Regulatory Framework
      • 8.6.4.5. Reimbursement Scenario
    • 8.6.5. Kuwait
      • 8.6.5.1. Key Country Dynamics
      • 8.6.5.2. Kuwait Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)
      • 8.6.5.3. Competitive/Market Scenario
      • 8.6.5.4. Regulatory Framework
      • 8.6.5.5. Reimbursement Scenario
    • 8.6.6. Rest of MEA Naltrexone and Buprenorphine Market Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 9. Competitive Landscape

  • 9.1. Market Participant Categorization
  • 9.2. Key Company Profiles
    • 9.2.1. Indivior PLC
      • 9.2.1.1. Company overview
      • 9.2.1.2. Financial performance
      • 9.2.1.3. Product benchmarking
      • 9.2.1.4. Strategic initiatives
    • 9.2.2. Collegium Pharmaceutical, Inc. (Parent company of BioDelivery Sciences International, Inc.)
      • 9.2.2.1. Company overview
      • 9.2.2.2. Financial performance
      • 9.2.2.3. Product benchmarking
      • 9.2.2.4. Strategic initiatives
    • 9.2.3. Alkermes plc
      • 9.2.3.1. Company overview
      • 9.2.3.2. Financial performance
      • 9.2.3.3. Product benchmarking
      • 9.2.3.4. Strategic initiatives
    • 9.2.4. Orexo AB
      • 9.2.4.1. Company overview
      • 9.2.4.2. Financial performance
      • 9.2.4.3. Product benchmarking
      • 9.2.4.4. Strategic initiatives
    • 9.2.5. Titan Pharmaceuticals, Inc.
      • 9.2.5.1. Company overview
      • 9.2.5.2. Financial performance
      • 9.2.5.3. Product benchmarking
      • 9.2.5.4. Strategic initiatives
    • 9.2.6. Omeros Corporation
      • 9.2.6.1. Company overview
      • 9.2.6.2. Financial performance
      • 9.2.6.3. Product benchmarking
      • 9.2.6.4. Strategic initiatives
    • 9.2.7. F. Hoffmann-La Roche Ltd.
      • 9.2.7.1. Company overview
      • 9.2.7.2. Financial performance
      • 9.2.7.3. Product benchmarking
      • 9.2.7.4. Strategic initiatives
    • 9.2.8. Camurus
      • 9.2.8.1. Company overview
      • 9.2.8.2. Financial performance
      • 9.2.8.3. Product benchmarking
      • 9.2.8.4. Strategic initiatives
    • 9.2.9. Sun Pharmaceutical Industries Ltd
      • 9.2.9.1. Company overview
      • 9.2.9.2. Financial performance
      • 9.2.9.3. Product benchmarking
      • 9.2.9.4. Strategic initiatives
    • 9.2.10. Braeburn, Inc.
      • 9.2.10.1. Company overview
      • 9.2.10.2. Financial performance
      • 9.2.10.3. Product benchmarking
      • 9.2.10.4. Strategic initiatives
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