골이식편 및 골대체물 시장 규모, 점유율, 동향 분석 보고서 : 재료 유형별, 용도별, 지역별, 부문별 예측(2025-2030년)

Bone Grafts And Substitutes Market Growth & Trends:

The global bone grafts and substitutes market size is expected to reach USD 4.60 billion by 2030, registering to grow at a CAGR of 6.6% from 2025 to 2030 according to a new report by Grand View Research, Inc. The increasing prevalence of orthopedic disorders and surge in number of orthopedic surgeries are likely to drive the market growth. In addition, technological advancements in developing advanced orthopedic grafts & substitutes and rising investments by leading players to meet increasing global demand for advanced grafts have further escalated the industry expansion.

Increasing demand for developing biocompatible bone grafts to reduce adverse reactions is driving the market. Increasing use of synthetic bone grafts with Hydroxyapatite and Tricalcium Phosphate, which has shown better biocompatibility as compared to others, is fueling the market growth. Market players are continuously developing new products with better biocompatibility, bioactivity, and suitable mechanical properties. For instance, in October 2020, Graftys received Medical Device Single Audit Program (MDSAP) certification for its Sterile Calcium Phosphate Resorbable Bone Void Fillers and related delivery systems in Australia, Brazil, Canada, and U.S. It also received CE recertification in Europe.

The increasing use of bone grafts in density is propelling the growth of dental bone grafts and substitutes market. The bone grafts are mostly used as a scaffold and filler to facilitate bone formation and promote healing. Dental implant surgery has now become very popular with advanced surgical techniques such as bone grafts and bone regeneration. Moreover, increasing demand and success rates of dental implants are fueling market growth. According to the American Academy of Implant Dentistry, as of 2020, the number of people getting dental implants has risen by 500,000 annually. The source also reported a success rate of 95% in the implant dentistry segment. Around 5 million implant procedures are performed in the U.S. every year.

Synthetic bone graft technology is benefiting advanced medicine, but the cost of such technologies is high, thus restraining market growth. The average price of DBM ranges from USD 600 to USD 865; that of bone morphogenetic protein matrix ranges from USD 3,450 to USD 5,000, and of synthetic ceramic & polymer-based bone grafts ranges from USD 893 to USD 2,000. In addition, reimbursement policies vary based on autografts and bone graft substitutes used, which increase the cost of procedures. This helps avoid incisions and difficulty in obtaining donor grafts. Therefore, the high cost of associated devices and technologies may hinder market growth.

Bone Grafts And Substitutes Market Report Highlights:

• The allograft segment held the largest revenue share of 60.2% in 2024 and is anticipated to witness significant growth opportunities during the forecast period.
• In the application segment, the spinal fusion sub-segment held the largest market share of 60.1% in 2024.
• The rising adoption of grafts for dental procedures is likely to provide lucrative opportunities for the dental segment throughout the forecast period. The grafts are usually used as scaffolds and filler to facilitate bone formation as well as to promote healing.
• North America bone grafts and substitutes market dominated the global market in 2024 and accounted for the largest revenue share of 42.1%.
• Some of the leading players include Smith & Nephew, Medtronic, and DePuy Synthes, as they have maintained their market position during the forecast period in terms of product penetration, regional presence, revenue, as well as strategic initiatives.

Table of Contents

Chapter 1 Research Methodology & Scope

• 1.1 Market Segmentation & Scope
  • 1.1.1 Estimates and Forecast Timeline
• 1.2 Segment Definitions
  • 1.2.1 Type Segment
  • 1.2.2 Application Segment
  • 1.2.3 Dental protein combined product segment definitions
• 1.3 Research Methodology
• 1.4 Information Procurement
  • 1.4.1 Purchased database:
  • 1.4.2 GVR's Internal Database
  • 1.4.3 Secondary sources
  • 1.4.4 Primary Research:
  • 1.4.5 Details of Primary Research
    • 1.4.5.1 Data For Primary Interviews In North america
    • 1.4.5.2 Data For Primary Interviews In Europe
    • 1.4.5.3 Data For Primary Interviews In Asia Pacific
    • 1.4.5.4 Data For Primary Interviews In Latin america
    • 1.4.5.5 Data For Primary Interviews In Middle East and Africa
• 1.5 Information or Data Analysis
  • 1.5.1 Data Analysis Models
• 1.6 Market Formulation & Validation
• 1.7 Model Details
  • 1.7.1 Commodity Flow Analysis
    • 1.7.1.1 Approach: Commodity Flow Approach
• 1.8 List of Secondary Sources
• 1.9 List of Primary Sources
• 1.10 Abbreviations
• 1.11 Report Objectives
• 1.12 Research Methodology for Dental Protein Combined Products Market
  • 1.12.1 Research Scope and Assumptions for Dental Protein Combined Products Market
  • 1.12.2 Research Methodology and Assumptions

Chapter 2 Executive Summary

• 2.1 Bone Grafts and Substitutes Market Snapshot
• 2.2 Bone Grafts and Substitutes Market Snapshot
• 2.3 Bone Grafts and Substitutes Market Competitive Landscape Snapshot

Chapter 3 Bone Grafts and Substitutes Market Variables and Trends

• 3.1 Market Lineage Outlook
  • 3.1.1 Ancillary/Related Market Outlook
• 3.2 Market Dynamics
  • 3.2.1 Market Driver Analysis
    • 3.2.1.1 Rising incidence of bone & joint disorders
    • 3.2.1.2 Advent of biocompatible synthetic graft
    • 3.2.1.3 Rising demand for dental bone grafts
    • 3.2.1.4 Technological advancements
    • 3.2.1.5 Rising geriatric population
  • 3.2.2 Market Restraint Analysis
    • 3.2.2.1 Stringent regulatory guidelines
    • 3.2.2.2 Risk of disease transmission
• 3.3 Bone Grafts and Substitutes Market Analysis Tools
  • 3.3.1 Industry Analysis - PORTER'S
  • 3.3.2 Industry Analysis - PEST
• 3.4 Bone Grafts and Substitute Industry: Product Pipeline Analysis
• 3.5 Types of Dental Surgeries Utilizing Non-Metal Dental Implants
• 3.6 Case Study Analysis

Chapter 4 Bone Grafts and Substitutes Market: Material Estimates & Trend Analysis

• 4.1 Bone Grafts and Substitutes Market: Material Outlook Key Takeaways
• 4.2 Bone Grafts and Substitutes Market: Material Movement Analysis
• 4.3 Allograft
  • 4.3.1 Allograft Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 4.3.2 Demineralized Bone Matrix (DBM)
    • 4.3.2.1 Demineralized Bone Matrix (DBM) Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 4.3.3 Others
    • 4.3.3.1 Others Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 4.4 Synthetic
  • 4.4.1 Synthetic Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 4.4.2 Ceramic
    • 4.4.2.1 Ceramic Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2.2 HAP
      • 4.4.2.2.1 HAP Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2.3 B-TCP
      • 4.4.2.3.1 B-TCP Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2.4 Alpha-Tricalcium Phosphate (alpha-TCP)
      • 4.4.2.4.1 Alpha-TCP Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2.5 Bi-Phasic Calcium Phosphates (BCP)
      • 4.4.2.5.1 Bi-Phasic Calcium Phosphates (BCP) Market Estimates And Forecasts, 2018 - 2030 (USD Million)
    • 4.4.2.6 Others
      • 4.4.2.6.1 Others Market Estimates And Forecasts, 2018- 2030 (USD Million)
  • 4.4.3 Composite
    • 4.4.3.1 Composite Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 4.4.4 Polymers
    • 4.4.4.1 Polymers Market Estimates And Forecasts, 2018 - 2030 (USD Million)
  • 4.4.5 BMP
    • 4.4.5.1 BMP Market Estimates And Forecasts, 2018 - 2030 (USD Million)

Chapter 5 Bone Grafts and Substitutes Market: Application Estimates & Trend Analysis

• 5.1 Bone Grafts and Substitutes Market: Application Outlook Key Takeaways
• 5.2 Bone Grafts and Substitutes Market: Application Movement Analysis
• 5.3 Craniomaxillofacial
  • 5.3.1 Craniomaxillofacial Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 5.4 Dental
  • 5.4.1 Dental Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 5.5 Foot & Ankle
  • 5.5.1 Foot & Ankle Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 5.6 Joint Reconstruction
  • 5.6.1 Joint Reconstruction Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 5.7 Long Bone
  • 5.7.1 Long Bone Market Estimates And Forecasts, 2018 - 2030 (USD Million)
• 5.8 Spinal Fusion
  • 5.8.1 Spinal Fusion Market Estimates And Forecasts, 2018 - 2030 (USD Million)

Chapter 6 Dental Protein Combined Products Market Analysis, by Product

• 6.1 Product Market Share Analysis, 2024 & 2030
• 6.2 Dental Protein Combined Products Market Estimates & Forecast, by Product (USD Million)
• 6.3 Dental Implants
  • 6.3.1 Dental implants Market, 2018 - 2030 (USD Million)
• 6.4 Dental Protein Combined Products Market Estimates & Forecast, by Product (USD Million)
• 6.5 Dental Bone Grafts
  • 6.5.1 Dental Bone Grafts Market, 2018 - 2030 (USD Million)
• 6.6 Dental Cements
  • 6.6.1 Dental Cements Market, 2018 - 2030 (USD Million)
• 6.7 Guided Tissue Regeneration (GTR) Membranes
  • 6.7.1 Guided Tissue Regeneration (GTR) Membranes Market, 2018 - 2030 (USD Million)
• 6.8 Others
  • 6.8.1 Others Market, 2018 - 2030 (USD Million)

Chapter 7 Bone Grafts and Substitutes Market: Regional Estimates & Trend Analysis

• 7.1 Bone Grafts and Substitutes Market: Regional Key takeaways
• 7.2 Bone Grafts and Substitutes Market, by Region, 2024 & 2030 (USD Million)
• 7.3 North America
  • 7.3.1 North America Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.3.2 U.S.
    • 7.3.2.1 Key country dynamics
    • 7.3.2.1 Regulatory Framework
    • 7.3.2.1 Competitive Scenario
    • 7.3.2.2 U.S. Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.3.3 Canada
    • 7.3.3.1 Key country dynamics
    • 7.3.3.1 Regulatory Framework
    • 7.3.3.2 Competitive Scenario
    • 7.3.3.3 Canada Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.3.4 Mexico
    • 7.3.4.1 Key country dynamics
    • 7.3.4.2 Regulatory Framework
    • 7.3.4.3 Competitive Scenario
    • 7.3.4.4 Mexico Bone Grafts and Substitutes Market Estimates and Forecasts
• 7.4 Europe
  • 7.4.1 Europe Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.2 UK
    • 7.4.2.1 Key country dynamics
    • 7.4.2.2 Regulatory Framework
    • 7.4.2.3 Competitive Scenario
    • 7.4.2.4 UK Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.3 Germany
    • 7.4.3.1 Key country dynamics
    • 7.4.3.2 Regulatory Framework
    • 7.4.3.3 Competitive Scenario
    • 7.4.3.4 Germany Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.4 France
    • 7.4.4.1 Key country dynamics
    • 7.4.4.2 Regulatory Framework
    • 7.4.4.3 Competitive Scenario
    • 7.4.4.4 France Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.5 Spain
    • 7.4.5.1 Key country dynamics
    • 7.4.5.2 Regulatory Framework
    • 7.4.5.3 Competitive Scenario
    • 7.4.5.4 Spain Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.6 Italy
    • 7.4.6.1 Key country dynamics
    • 7.4.6.2 Regulatory Framework
    • 7.4.6.3 Competitive Scenario
    • 7.4.6.4 Italy Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.7 Denmark
    • 7.4.7.1 Key country dynamics
    • 7.4.7.2 Regulatory Framework
    • 7.4.7.3 Competitive Scenario
    • 7.4.7.4 Denmark Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.8 Sweden
    • 7.4.8.1 Key country dynamics
    • 7.4.8.2 Regulatory Framework
    • 7.4.8.3 Competitive Scenario
    • 7.4.8.4 Sweden Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.4.9 Norway
    • 7.4.9.1 Key country dynamics
    • 7.4.9.2 Regulatory Framework
    • 7.4.9.3 Competitive Scenario
    • 7.4.9.4 Norway Bone Grafts and Substitutes Market Estimates and Forecasts
• 7.5 Asia Pacific
  • 7.5.1 Asia Pacific Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.2 Japan
    • 7.5.2.1 Key country dynamics
    • 7.5.2.2 Regulatory Framework
    • 7.5.2.3 Competitive Scenario
    • 7.5.2.4 Japan Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.3 China
    • 7.5.3.1 Key country dynamics
    • 7.5.3.2 Regulatory Framework
    • 7.5.3.3 Competitive Scenario
    • 7.5.3.4 China Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.4 India
    • 7.5.4.1 Key country dynamics
    • 7.5.4.2 Regulatory Framework
    • 7.5.4.3 Competitive Scenario
    • 7.5.4.4 India Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.5 Australia
    • 7.5.5.1 Key country dynamics
    • 7.5.5.2 Regulatory Framework
    • 7.5.5.3 Competitive Scenario
    • 7.5.5.4 Australia Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.6 Thailand
    • 7.5.6.1 Key country dynamics
    • 7.5.6.2 Regulatory Framework
    • 7.5.6.3 Competitive Scenario
    • 7.5.6.4 Thailand Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.5.7 South Korea
    • 7.5.7.1 Key country dynamics
    • 7.5.7.2 Regulatory Framework
    • 7.5.7.3 Competitive Scenario
    • 7.5.7.4 South Korea Bone Grafts and Substitutes Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.6 Latin America
  • 7.6.1 Latin America Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.6.2 Brazil
    • 7.6.2.1 Key country dynamics
    • 7.6.2.1 Regulatory Framework
    • 7.6.2.2 Competitive Scenario
    • 7.6.2.3 Brazil Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.6.3 Argentina
    • 7.6.3.1 Key country dynamics
    • 7.6.3.2 Regulatory Framework
    • 7.6.3.3 Competitive Scenario
    • 7.6.3.4 Argentina Bone Grafts and Substitutes Market Estimates and Forecasts
• 7.7 Middle East & Africa (MEA)
  • 7.7.1 MEA Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.7.2 South Africa
    • 7.7.2.1 Key country dynamics
    • 7.7.2.2 Regulatory Framework
    • 7.7.2.3 Competitive Scenario
    • 7.7.2.4 South Africa Bone Grafts and Substitutes market estimates and forecasts
  • 7.7.3 Saudi Arabia
    • 7.7.3.1 Key Country Dynamics
    • 7.7.3.2 Regulatory Framework
    • 7.7.3.3 Competitive Scenario
    • 7.7.3.4 Saudi Arabia Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.7.4 UAE
    • 7.7.4.1 Key country dynamics
    • 7.7.4.2 Regulatory Framework
    • 7.7.4.3 Competitive Scenario
    • 7.7.4.4 UAE Bone Grafts and Substitutes Market Estimates and Forecasts
  • 7.7.5 Kuwait
    • 7.7.5.1 Key country dynamics
    • 7.7.5.2 Regulatory Framework
    • 7.7.5.3 Competitive Scenario
    • 7.7.5.4 Kuwait Bone Grafts and Substitutes Market Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 8 Company Profiles

• 8.1. Recent Developments & Impact Analysis, By Key Market Participants
• 8.2. Company Categorization
• 8.3 AlloSource
  • 8.3.1 Company overview
  • 8.3.2 Financial Performance
  • 8.3.3 Product benchmarking
  • 8.3.4 Strategic Initiatives
• 8.4 Baxter
  • 8.4.1 Company overview
  • 8.4.2 Financial Performance
  • 8.4.3 Product benchmarking
  • 8.4.4 Strategic Initiatives
• 8.5 DePuy Synthes
  • 8.5.1 Company overview
  • 8.5.2 Financial Performance
  • 8.5.3 Product benchmarking
  • 8.5.4 Strategic Initiatives
• 8.6 Medtronic
  • 8.6.1 Company overview
  • 8.6.2 Financial Performance
  • 8.6.3 Product benchmarking
  • 8.6.6 Strategic Initiatives
• 8.7 NuVasive, Inc.
  • 8.7.1 Company overview
  • 8.7.2 Financial Performance
  • 8.7.3 Product benchmarking
  • 8.7.4 Strategic Initiatives
• 8.8 Orthofix Medical, Inc.
  • 8.8.1 Company overview
  • 8.8.2 Financial Performance
  • 8.8.3 Product benchmarking
  • 8.8.4 Strategic Initiatives
• 8.9 Smith + Nephew
  • 8.9.1 Company overview
  • 8.9.2 Financial Performance
  • 8.9.3 Product benchmarking
  • 8.9.4 Strategic Initiatives
• 8.10 Stryker
  • 8.10.1 Company overview
  • 8.10.2 Financial Performance
  • 8.10.3 Product benchmarking
  • 8.10.4 Strategic Initiatives
• 8.11 Biobank
  • 11.11.1 Company overview
  • 11.11.2 Financial Performance
  • 11.11.3 Product benchmarking
  • 11.11.4 Strategic Initiatives
• 8.12 OST Laboratories
  • 8.12.1 Company overview
  • 8.12.2 Financial Performance
  • 8.12.3 Product benchmarking
  • 8.12.4 Product benchmarking
• 8.13 Zimmer Biomet
  • 8.13.1 Company overview
  • 8.13.2 Financial performance
  • 8.13.3 Product benchmarking
  • 8.13.4 Strategic initiatives
• 8.14 Geistlich Pharma AG
  • 8.14.1 Company overview
  • 8.14.2 Financial performance
  • 8.14.3 Product benchmarking
  • 8.14.4 Strategic initiatives