폐암 치료제 시장 : 치료 유형, 투여 방법, 치료 라인, 병기, 처방 상황, 유통 채널, 암종, 최종사용자별 - 세계 예측(2025-2032년)

The Lung Cancer Therapeutics Market is projected to grow by USD 59.89 billion at a CAGR of 8.70% by 2032.

Comprehensive introduction to the evolving scientific, clinical, and health system dynamics shaping lung cancer therapeutic innovation and delivery

Lung cancer therapeutics occupy a pivotal position within oncology due to persistent clinical need, rapid scientific advances, and evolving regulatory and reimbursement landscapes. Recent years have seen a shift from one-size-fits-all cytotoxic approaches toward precision medicine paradigms that harness targeted therapies and immune modulation. This transformation is underpinned by deeper molecular characterization of tumors, broader adoption of companion diagnostics, and more sophisticated clinical trial designs that accelerate therapeutic validation while refining patient selection.

Moreover, the clinical community is increasingly focused on integrating multimodal regimens that combine systemic agents with localized interventions, aiming to improve survival outcomes while preserving quality of life. Health systems and payers are adapting to long-term treatment pathways that raise new questions about value, affordability, and equitable access. Consequently, stakeholders across industry, clinical practice, and policy are re-evaluating development strategies and commercial models to align scientific promise with real-world delivery. In this context, careful synthesis of clinical evidence, regulatory signals, supply chain resilience, and stakeholder incentives becomes essential for guiding next-wave investments and market entry strategies.

High-impact shifts in molecular characterization, combination immuno-oncology approaches, and regulatory adaptation that are redefining therapeutic strategies for lung cancer

The landscape of lung cancer therapeutics is experiencing transformative shifts driven by convergence of scientific breakthroughs, regulatory evolution, and changing care paradigms. Advances in molecular oncology have expanded actionable targets beyond classical driver mutations, while next-generation sequencing and liquid biopsy technologies have enabled earlier and more accurate detection of actionable biomarkers. At the same time, immuno-oncology has matured into nuanced combination strategies that seek to convert durable responders into a larger patient cohort by pairing checkpoint inhibitors with targeted agents, antibody-drug conjugates, or novel immune modulators.

Regulatory bodies are also adapting, offering accelerated and adaptive pathways that reward clinically meaningful improvements and facilitate conditional approvals tied to real-world evidence generation. Payer frameworks are beginning to incorporate outcomes-based contracting and indication-specific pricing to manage long-term cost exposure. Operationally, pharmaceutical and biotech companies are forging deeper collaborations with diagnostic developers, contract research organizations, and specialized service providers to streamline development timelines and ensure diagnostic-drug co-deployment. As a result, competitive differentiation increasingly depends on integrated evidence packages, scalable manufacturing, and flexible commercialization strategies that account for heterogeneous patient populations and diverse care settings.

Integrated analysis of how 2025 United States tariff measures are reshaping supply chain architectures, manufacturing decisions, and procurement strategies across lung cancer therapeutics

The cumulative effects of tariff actions originating in the United States in 2025 have introduced new layers of complexity across the lung cancer therapeutics value chain, influencing production costs, supply chain design, and sourcing strategies. Tariff adjustments that apply to raw materials, active pharmaceutical ingredients, and specialized equipment have created incentives for sponsors and contract manufacturing partners to reassess geographic footprints and supplier portfolios. In response, many organizations have initiated dual-sourcing strategies and closer supplier partnerships to mitigate single-point vulnerabilities and preserve continuity of critical reagent and component flows.

Beyond direct cost implications, tariffs have accelerated conversations around onshoring and regional manufacturing capacity as a means to shorten lead times and reduce exposure to cross-border trade volatility. Such strategic moves typically require significant capital allocation and regulatory alignment, particularly when relocating sterile injectable or biologic drug production. Consequently, some developers have prioritized process intensification and modular manufacturing technologies to achieve flexibility without fully relocating operations.

Additionally, tariffs have ripple effects on ancillary services, including diagnostic test production and medical device supply chains that support therapeutic administration and monitoring. Health systems are adapting procurement practices to balance near-term budgetary pressures against long-term resilience, often negotiating longer-term contracts with manufacturers or leveraging strategic inventories for critical inputs. In aggregate, these adjustments emphasize the importance of supply chain transparency, scenario planning, and close engagement with customs and trade specialists to maintain program timelines and patient access in a shifting tariff environment.

In-depth segmentation insights across therapeutic modalities, lines of care, tumor types, administration routes, and distribution channels shaping development and access

A nuanced understanding of segment-level dynamics is essential for aligning development and commercial strategies with clinical realities and delivery channels. When therapies are analyzed by therapy type, it is important to consider the distinct developmental pathways and clinical utility of chemotherapy, immunotherapy, radiation therapy, and targeted therapy. Chemotherapy retains a foundational role in certain regimens, with alkylating agents, platinum-based compounds, taxanes, and topoisomerase inhibitors each occupying defined niches in combination and sequential approaches. Immunotherapy encompasses checkpoint blockade modalities such as CTLA-4 inhibitors, PD-1 inhibitors, and PD-L1 inhibitors, which vary in mechanism, dosing paradigms, and biomarker dependencies. Radiation therapy remains a critical local modality and includes brachytherapy, external beam radiation, and stereotactic body radiation, each offering differential applicability based on tumor location and intent of care. Targeted therapy is increasingly stratified by molecular targets, including ALK inhibitors, BRAF inhibitors, EGFR inhibitors, and ROS1 inhibitors, which demand companion diagnostic alignment and resistance-management strategies.

Line-of-therapy segmentation reveals strategic inflection points for clinical development and commercialization. Adjuvant and neoadjuvant settings require robust translational endpoints and longer-term outcome demonstration, while first-line, maintenance, second-line, and third-line-and-beyond indications demand clear differentiation on safety, durability, and sequencing compatibility. Differentiating a candidate in early lines often unlocks broader adoption but also requires head-to-head or pragmatic comparative evidence. When classifying by type of lung cancer, non-small cell lung cancer and small cell lung cancer present divergent biological behaviors and therapeutic modalities; NSCLC benefits from a rich targetable landscape and immunotherapy responsiveness, whereas SCLC requires intensified focus on systemic combinations and early detection strategies.

Mode-of-administration considerations-whether inhalation, injectable, or oral-shape patient adherence, site-of-care economics, and distribution logistics. Oral agents facilitate outpatient continuity and can reduce infusion resource burden, but raise adherence monitoring and drug-drug interaction considerations. Inhalation delivery offers localized exposure for select therapeutic modalities but depends on device compatibility and payer acceptance. Injectable therapeutics, particularly biologics and ADCs, demand infusion infrastructure and cold-chain logistics. Finally, distribution channel segmentation spanning hospital pharmacies, online pharmacies, retail pharmacies, and specialty clinics influences access pathways and reimbursement negotiation points. Each channel has unique contracting dynamics and patient support program implications, with specialty clinics often central to complex therapy administration and monitoring. Taken together, these segmentation lenses inform prioritization of clinical programs, supply strategies, and commercial engagement plans that align with clinical utility and care delivery realities.

Critical regional dynamics across the Americas, Europe Middle East & Africa, and Asia-Pacific that determine regulatory access, reimbursement, and distribution strategies for therapeutics

Regional dynamics exert strong influence on regulatory timelines, reimbursement frameworks, and commercial execution strategies. In the Americas, regulatory authorities and payers emphasize comparative effectiveness and value-based arrangements, with heterogeneous adoption patterns across public and private systems. This region often leads in rapid adoption of novel targeted agents and immunotherapies but faces pressure from payer-driven utilization management and pricing negotiations that necessitate robust health economic evidence and patient support programs.

Across Europe, the Middle East, and Africa, regulatory pathways and reimbursement approaches vary widely. Western European markets typically demand comprehensive health technology assessments and real-world evidence, while emerging markets in the region may prioritize affordability and access programs. Regulatory harmonization efforts and cross-border clinical collaborations are increasingly important for achieving scale in drug development and post-approval evidence generation. The Middle East and Africa present both opportunity and complexity due to variable infrastructure, heterogeneous disease burden reporting, and different procurement models that require adaptive market-entry tactics.

The Asia-Pacific region represents a diverse landscape where rapid adoption can hinge on local regulatory reforms, domestic manufacturing capacity, and national cancer control priorities. Several countries in the region are accelerating approvals for targeted therapies and immunotherapies through conditional pathways tied to real-world evidence, while others maintain stringent local clinical requirements. Additionally, evolving initiatives to expand genomic testing and decentralized care delivery are reshaping patient identification and treatment uptake. Collectively, these regional nuances highlight the need for geographically tailored evidence strategies, flexible pricing arrangements, and supply-chain designs that accommodate regulatory and infrastructural diversity.

Strategic competitive overview emphasizing integrated portfolios, biotech innovation pipelines, and partner ecosystems that accelerate lung cancer therapeutic advancement

The competitive landscape in lung cancer therapeutics is characterized by a blend of large pharmaceutical companies, biotechs advancing novel modalities, and specialized service providers that enable rapid development and commercialization. Market leaders tend to differentiate through integrated portfolios that combine late-stage assets, pipeline depth, and established commercial infrastructure. These organizations often leverage global regulatory experience and payer engagement capabilities to accelerate launches and secure place-in-therapy positions.

Smaller biotechs and academic spinouts contribute disproportionate innovation, particularly in emerging modalities such as bispecific antibodies, antibody-drug conjugates, and cell-based therapies. These entities frequently pursue strategic partnerships or selective co-development agreements with larger sponsors to access development and commercial scale. Contract research and manufacturing partners play an instrumental role in enabling flexible development timelines and managing biologics complexity, while diagnostics developers are critical collaborators for companion assays and biomarker-driven clinical strategies. Across the competitive set, success increasingly depends on integrated evidence generation, adaptable commercial models, and the ability to demonstrate real-world benefit in diverse health system contexts.

Actionable strategic imperatives for developers and commercial teams to align biomarker-driven development, supply resilience, and payer-ready evidence generation

Industry leaders should prioritize a set of actionable initiatives to navigate clinical complexity, supply-chain disruption, and payer demands. First, aligning development programs with robust biomarker strategies and companion diagnostics will improve patient selection and strengthen value propositions for payers and clinicians. Investing early in translational research and adaptive trial designs can shorten development cycles and create clearer differentiation against standard-of-care comparators. Secondly, building supply-chain resilience through diversified sourcing, regional manufacturing partnerships, and modular production technologies will mitigate tariff- and disruption-related risks while preserving delivery timelines.

Third, commercial teams should design evidence-generation plans that include real-world data collection, health economic modelling, and outcomes-based contracting options to address payer concerns about long-term value. Engaging key opinion leaders and multidisciplinary treatment centers early can facilitate guideline inclusion and appropriate uptake. Fourth, optimizing patient support and adherence programs-particularly for oral and outpatient-administered therapeutics-will drive persistence and outcomes, requiring integration with digital tools and specialty pharmacy networks. Finally, companies should consider flexible pricing and access strategies that reflect regional affordability constraints and promote equitable access, leveraging tiered contracting, compassionate use frameworks, and strategic partnerships with public and non-profit stakeholders. Taken together, these actions create a pragmatic road map for translating scientific advances into sustainable clinical and commercial impact.

Transparent research methodology combining literature review, expert input, and cross-functional evidence integration to support actionable conclusions and decision-making

The research approach underpinning this analysis combines systematic literature synthesis, expert interviews, and cross-functional evidence triangulation to ensure robust and actionable insights. Peer-reviewed clinical data, regulatory guidance documents, and public health advisories were reviewed to anchor clinical and regulatory interpretations. In addition, primary qualitative inputs from clinicians, pharmacoeconomists, supply-chain specialists, and diagnostic developers informed practical considerations around implementation, patient pathways, and reimbursement dynamics.

Methodologically, the study emphasizes evidence integration across preclinical mechanistic understanding, clinical trial outcomes, and real-world practice patterns. Analytical techniques included comparative therapeutic class assessment, scenario planning for supply-chain contingencies, and qualitative valuation of commercial models. Care was taken to validate assumptions through subject matter expert workshops and to cross-check policy interpretations with publicly available regulatory communications. Limitations include the rapidly evolving nature of clinical evidence and policy environments, which the methodology addresses by recommending periodic updates and staged deep dives tied to major regulatory or clinical inflection points.

Concluding synthesis emphasizing the interplay of scientific innovation, operational resilience, and payer-aligned evidence strategies to achieve durable patient impact

In conclusion, lung cancer therapeutics stand at a juncture where scientific momentum must be matched by operational dexterity and stakeholder-aligned value demonstration. Advances in molecular targeting, immuno-oncology, and diagnostics have expanded therapeutic possibilities, yet commercialization success will hinge on the ability to translate those advances into accessible, sustainable care pathways. Supply-chain disruptions and trade policy shifts have underscored the importance of resilience planning, while payer expectations increasingly demand comprehensive real-world evidence and outcomes-focused contracting.

Looking forward, stakeholders who integrate biomarker-driven development with flexible manufacturing, region-specific access strategies, and payer-oriented evidence plans will be best positioned to convert clinical innovation into meaningful patient impact. By maintaining close collaboration across clinical, regulatory, commercial, and supply-chain disciplines, organizations can navigate complexity and accelerate the translation of promising therapies into standard-of-care options that improve outcomes for patients with lung cancer.

Table of Contents

1. Preface

• 1.1. Objectives of the Study
• 1.2. Market Segmentation & Coverage
• 1.3. Years Considered for the Study
• 1.4. Currency & Pricing
• 1.5. Language
• 1.6. Stakeholders

2. Research Methodology

3. Executive Summary

4. Market Overview

5. Market Insights

• 5.1. Expansion of immunotherapy indications exploring novel checkpoint targets beyond PD-1 and PD-L1 in lung cancer
• 5.2. Integration of AI-driven radiomics and genomics for predictive biomarker identification in lung cancer therapy
• 5.3. Emerging bispecific antibody approaches targeting two oncogenic pathways in NSCLC treatment
• 5.4. Incorporation of liquid biopsy assays for personalized monitoring of therapeutic response in lung cancer
• 5.5. Development of novel KRAS G12C inhibitors and combination regimens to overcome resistance in NSCLC
• 5.6. Advancements in inhalable nanocarrier-based drug delivery systems for targeted lung cancer therapy
• 5.7. Growing emphasis on EGFR exon 20 insertion mutation therapies and clinical trial outcomes in NSCLC
• 5.8. Adoption of real-world evidence frameworks to accelerate regulatory approvals in lung cancer treatment pathways
• 5.9. Emergence of cellular therapies including TCR-T and NK cell approaches for advanced lung cancer management
• 5.10. Focus on overcoming resistance mechanisms in targeted and immunotherapy treatments

6. Cumulative Impact of United States Tariffs 2025

7. Cumulative Impact of Artificial Intelligence 2025

8. Lung Cancer Therapeutics Market, by Therapy Type

• 8.1. Chemotherapy
  • 8.1.1. Alkylating Agents
  • 8.1.2. Platinum-Based
  • 8.1.3. Taxanes
  • 8.1.4. Topoisomerase Inhibitors
• 8.2. Immunotherapy
  • 8.2.1. CTLA-4 Inhibitors
  • 8.2.2. PD-1 Inhibitors
  • 8.2.3. PD-L1 Inhibitors
• 8.3. Radiation Therapy
  • 8.3.1. Brachytherapy
  • 8.3.2. External Beam Radiation
  • 8.3.3. Stereotactic Body Radiation
• 8.4. Supportive Care
  • 8.4.1. Antiemetics
  • 8.4.2. Bone-Modifying Agents
  • 8.4.3. Hematopoietic Growth Factors
• 8.5. Surgery
• 8.6. Targeted Therapy
  • 8.6.1. Anaplastic Lymphoma Kinase (ALK) Inhibitors
  • 8.6.2. BRAF Inhibitors
  • 8.6.3. EGFR Inhibitors

9. Lung Cancer Therapeutics Market, by Mode Of Administration

• 9.1. Inhalation
• 9.2. Injectable
• 9.3. Oral

10. Lung Cancer Therapeutics Market, by Line Of Therapy

• 10.1. First-Line
• 10.2. Second-Line
• 10.3. Third-Line & Beyond

11. Lung Cancer Therapeutics Market, by Disease Stage

• 11.1. Stage I
• 11.2. Stage II
• 11.3. Stage III
• 11.4. Stage IV

12. Lung Cancer Therapeutics Market, by Prescription Status

• 12.1. Branded
• 12.2. Generic

13. Lung Cancer Therapeutics Market, by Distribution Channel

• 13.1. Offline Retail
• 13.2. Online Retail

14. Lung Cancer Therapeutics Market, by Cancer Type

• 14.1. Non-Small Cell Lung Cancer (NSCLC)
  • 14.1.1. Adenocarcinoma
  • 14.1.2. Large Cell Carcinoma
  • 14.1.3. Squamous Cell Carcinoma
• 14.2. Small Cell Lung Cancer (SCLC)

15. Lung Cancer Therapeutics Market, by End User

• 15.1. Ambulatory Infusion Centers
• 15.2. Cancer Centers
• 15.3. Homecare Settings
• 15.4. Hospitals

16. Lung Cancer Therapeutics Market, by Region

• 16.1. Americas
  • 16.1.1. North America
  • 16.1.2. Latin America
• 16.2. Europe, Middle East & Africa
  • 16.2.1. Europe
  • 16.2.2. Middle East
  • 16.2.3. Africa
• 16.3. Asia-Pacific

17. Lung Cancer Therapeutics Market, by Group

• 17.1. ASEAN
• 17.2. GCC
• 17.3. European Union
• 17.4. BRICS
• 17.5. G7
• 17.6. NATO

18. Lung Cancer Therapeutics Market, by Country

• 18.1. United States
• 18.2. Canada
• 18.3. Mexico
• 18.4. Brazil
• 18.5. United Kingdom
• 18.6. Germany
• 18.7. France
• 18.8. Russia
• 18.9. Italy
• 18.10. Spain
• 18.11. China
• 18.12. India
• 18.13. Japan
• 18.14. Australia
• 18.15. South Korea

19. Competitive Landscape

• 19.1. Market Share Analysis, 2024
• 19.2. FPNV Positioning Matrix, 2024
• 19.3. Competitive Analysis
  • 19.3.1. AbbVie Inc.
  • 19.3.2. Amgen Inc.
  • 19.3.3. Astellas Pharma Inc.
  • 19.3.4. AstraZeneca PLC
  • 19.3.5. Bayer AG
  • 19.3.6. Boehringer Ingelheim International GmbH
  • 19.3.7. Johnson & Johnson Services, Inc.
  • 19.3.8. Merck & Co., Inc.
  • 19.3.9. Novartis AG
  • 19.3.10. Pfizer Inc.
  • 19.3.11. Sanofi S.A
  • 19.3.12. Takeda Pharmaceutical Company Limited