폐기종 치료 시장 : 치료법별, 약제 클래스별, 치료 라인별, 투여 경로별, 제형별, 유통경로별, 제품 유형별 - 세계 예측(2025-2032년)

The Emphysema Treatment Market is projected to grow by USD 11.94 billion at a CAGR of 7.22% by 2032.

A comprehensive introduction outlining the evolving emphysema treatment environment, clinical priorities, and emerging pressures shaping therapeutic decision-making

Emphysema remains a clinical and commercial priority within chronic respiratory disease management, driven by its progressive pathology, symptomatic burden, and high healthcare utilization. The therapeutic landscape comprises both pharmacological and surgical approaches, each carrying distinct clinical objectives: pharmacological strategies aim to control inflammation, relieve airflow obstruction, and reduce exacerbations, while surgical options are reserved for carefully selected patients to improve lung mechanics and quality of life. This introduction frames the converging forces reshaping patient care, innovation pipelines, and the payer environment.

Over recent years, clinical practice has shifted toward personalized treatment pathways that integrate long-acting bronchodilators, targeted anti-inflammatory regimens, and precision selection for surgical intervention. Advances in device technology and procedural techniques have refined therapeutic delivery, improving tolerability and adherence. At the same time, health systems are emphasizing value-based outcomes, prompting stakeholders to reevaluate treatment appropriateness, long-term management strategies, and interventions that meaningfully reduce hospital admissions.

Given these dynamics, industry participants-spanning drug developers, device manufacturers, payers, and provider networks-must reconcile clinical evidence with operational realities to design scalable solutions. This introduction sets the stage for a deeper exploration of how shifting scientific, regulatory, and economic pressures create both constraints and opportunities across the continuum of emphysema care.

How innovations in pharmacotherapy, device delivery, and procedural techniques are reshaping emphysema care pathways and stakeholder expectations

The landscape of emphysema treatment is undergoing transformative shifts driven by innovation in pharmacotherapy, refinement of surgical techniques, and a growing emphasis on integrated care models. Novel drug combinations and device platforms are expanding clinical options, while minimally invasive procedures and valve therapies provide alternatives for patients who historically had limited choices. These changes are not isolated; they interact with regulatory decisions, reimbursement pathways, and clinical guideline updates to accelerate adoption curves for certain interventions.

Concurrently, the shift toward patient-centered care has elevated metrics such as quality of life, exercise tolerance, and exacerbation reduction over simple physiological markers. This reorientation compels developers to demonstrate real-world effectiveness and durability of benefit. Advances in inhalation technologies, including dry powder and soft mist inhalers, are increasing the precision and convenience of drug delivery, thereby improving adherence and therapeutic effect. On the surgical side, refinements in lung volume reduction surgery and bronchoscopic valve therapy are generating new evidence for subgroup benefit, prompting multidisciplinary teams to reevaluate candidacy criteria.

These transformative shifts are amplified by digital health integration, remote monitoring, and telemedicine-enabled follow-up, which collectively support early intervention and tailored maintenance strategies. As stakeholders respond, the market is recalibrating toward interventions that can provide measurable patient benefit while aligning with payer expectations for cost-effectiveness and demonstrable outcomes.

Operational and strategic consequences of United States tariff realignments in 2025 on supply chains, procurement resilience, and clinical continuity for emphysema therapies

The cumulative impact of tariff and trade policy changes in the United States in 2025 created an operational context that healthcare manufacturers and distributors had to navigate carefully. Shifts in tariff schedules affected the importation costs of specialized inhalation devices, certain biopharmaceutical components, and surgical equipment used in advanced pulmonary procedures. Manufacturers responded by reassessing supply chains, renegotiating sourcing agreements, and accelerating localization of critical components to mitigate exposure to trade-related cost volatility.

These adjustments reverberated downstream, influencing procurement strategies for hospital systems and integrated care networks that procure a mix of pharmacological therapies and procedural devices. Some organizations shifted toward longer term contracting and regional supplier diversification to minimize disruptions. Regulatory and customs compliance requirements also increased administrative overhead, prompting stakeholders to invest in supply chain resilience and scenario planning.

Importantly, the policy environment catalyzed conversations about domestic manufacturing capacity and strategic inventory management for high-value components. The aggregate effect was a renewed focus on manufacturing agility and risk mitigation across the product lifecycle, with commercial teams integrating tariff sensitivity into pricing, contracting, and go-to-market planning to preserve access and maintain clinical continuity for patients reliant on complex emphysema treatments.

Multidimensional segmentation insights revealing how treatment type, drug class, therapy line, and delivery channels dictate clinical adoption and commercial positioning

Key segmentation insights illuminate how therapeutic choices and commercial pathways diverge across treatment type, drug class, therapy line, route of administration, dosage form, distribution channel, and product type. Based on treatment type, the market distinguishes pharmacological options-studied across antibiotics, bronchodilators, corticosteroids, and mucolytics-from surgical approaches that include bullectomy, lung transplantation, lung volume reduction surgery, and valve therapy; this dichotomy underscores the need for coordinated care pathways that integrate medication optimization with procedural selection criteria.

When considered through the lens of drug class, anticholinergics, beta-agonists, and combination drugs dominate clinical strategies for bronchodilation and symptom control, and their evolving formulations and delivery systems directly influence adherence and clinical outcomes. Therapy line segmentation-adjunctive, first-line, maintenance, and rescue-reveals how interventions are positioned across the patient journey; within maintenance strategies, combination therapy, long-acting anticholinergics, and long-acting beta-agonists are central to sustained disease control, while rescue options rely on short-acting anticholinergics and short-acting beta-agonists to address acute symptom flares.

Route of administration is a critical commercial and clinical differentiator: inhalation modalities such as dry powder inhaler, metered dose inhaler, nebulizer, and soft mist inhaler remain primary for chronic management, whereas intravenous approaches-infusion and injection-are typically reserved for acute care or hospital-based interventions, and oral formulations including capsule, solution, and tablet provide convenience for certain therapeutic classes. Dosage form segmentation across capsule, inhaler, nebulizer, solution, and tablet aligns closely with route considerations and patient adherence profiles. Distribution channel patterns-hospital pharmacy, online pharmacy, and retail pharmacy-reflect evolving purchasing behaviors and the increasing relevance of omnichannel access to therapies. Finally, product type segmentation between brand and generic options determines pricing dynamics, formulary placement, and uptake, particularly where generics enable broader access but branded innovations support premium positioning. Collectively, these segmentation lenses offer a multidimensional view that informs product development, commercial targeting, and clinical pathway design.

How regional regulatory, reimbursement, and healthcare delivery differences across the Americas, Europe Middle East & Africa, and Asia-Pacific shape access and commercialization strategies

Regional dynamics exert a strong influence on clinical practice, regulatory frameworks, and commercial strategy across the Americas, Europe, Middle East & Africa, and Asia-Pacific. In the Americas, emphasis on integrated health systems and value-based care models has prioritized therapies and interventions that demonstrably reduce hospitalizations and improve long-term patient outcomes, prompting payers and providers to scrutinize comparative effectiveness and total cost of care. This environment fuels interest in durable maintenance regimens and device innovations that support adherence.

Within Europe, Middle East & Africa, diverse regulatory pathways and heterogeneous healthcare funding mechanisms require tailored market access plans that account for country-specific reimbursement criteria and clinical guideline adoption. Stakeholders in this region often balance innovative therapeutics with local affordability considerations, creating opportunities for differentiated access strategies that pair clinical evidence with pragmatic pricing models. Across Asia-Pacific, rapid adoption of advanced inhalation technologies and growing investment in specialist pulmonary services are expanding the addressable patient population for both pharmacological and procedural interventions; however, variations in healthcare infrastructure and reimbursement across countries necessitate flexible commercialization approaches.

These regional distinctions underscore the importance of aligning clinical development and market access activities with localized evidence generation, stakeholder engagement, and distribution strategies. Companies that tailor their evidence packages, delivery modalities, and pricing structures to regional priorities are better positioned to achieve sustainable adoption and to scale interventions across multiple healthcare contexts.

Competitive profile and strategic imperatives for companies advancing pharmacological, device-based, and procedural solutions to address multifaceted emphysema care needs

Competitive dynamics in emphysema treatment are shaped by a mix of established pharmaceutical companies, specialized device manufacturers, and emerging biotech organizations pursuing novel therapeutic modalities. Incumbent players leverage broad respiratory portfolios, deep clinician relationships, and distribution networks to maintain access across hospitals and retail channels, while emerging entrants focus on differentiated mechanisms, targeted device-drug combinations, or procedural innovation to create clinical and commercial niches. Strategic partnerships and licensing agreements remain pivotal as companies aim to combine clinical expertise with device engineering or to accelerate market entry through co-development.

R&D intensity is concentrated on improving patient outcomes through longer-acting agents, combination formulations, and inhaler technologies that reduce systemic exposure and improve adherence. On the procedural side, device refinements and improved patient selection algorithms are expanding the candidate pool for lung volume reduction and valve therapies. Corporate strategy increasingly blends lifecycle management of legacy products with targeted investment in evidence generation to support label expansion or new guideline recommendations.

M&A and alliance activity gravitates toward capability gaps-such as inhalation device platforms or digital health solutions that enable remote monitoring and adherence support. Companies that can demonstrate integrated value propositions combining clinical efficacy, improved patient experience, and logistical simplicity stand to gain traction with payers and providers. Overall, competitive success hinges on evidence-driven differentiation, agile commercialization models, and close engagement with multidisciplinary clinical teams.

Actionable strategic recommendations for industry leaders to align clinical evidence, device innovation, supply chain resilience, and regional market access execution

Industry leaders should pursue a set of actionable recommendations that align clinical differentiation with commercial pragmatism and operational resilience. First, prioritize integrated evidence generation that pairs randomized controlled trial data with real-world outcomes, emphasizing measures such as exacerbation reduction, hospitalization avoidance, and quality of life improvements to meet payer and guideline expectations. Translate these clinical data into clear value narratives that address both short-term resource impact and long-term health benefits.

Second, invest in device and formulation optimization to enhance adherence and patient experience; innovations that simplify dosing, reduce handling complexity, or improve delivery efficiency can materially affect therapeutic efficacy in routine practice. Third, strengthen supply chain resilience by diversifying suppliers, localizing critical manufacturing capabilities where feasible, and incorporating tariff sensitivity into procurement and pricing models to reduce exposure to trade disruption. Fourth, tailor market access strategies to regional realities by developing country-specific evidence packages and adaptive pricing approaches that respect local reimbursement frameworks while preserving commercial viability.

Fifth, pursue strategic partnerships that combine clinical expertise, device engineering, and digital health capabilities to create bundled solutions that resonate with multidisciplinary care teams. Finally, embed patient-centricity across development and commercial activities by leveraging patient-reported outcomes, adherence analytics, and support programs that facilitate sustained engagement. These recommendations together support robust clinical uptake and sustainable commercial performance.

An evidence-driven research methodology blending systematic literature review, clinician and executive interviews, and supply chain policy analysis to validate insights

The research methodology underpinning this analysis combined rigorous secondary intelligence with targeted qualitative engagement to ensure a comprehensive, evidence-based perspective. A systematic review of peer-reviewed clinical literature, regulatory guidance, and public health directives provided the foundational clinical and scientific context. This review was complemented by an appraisal of device approvals, procedural technique literature, and technology assessment reports to capture advancements in both pharmacological and surgical domains.

To enrich the secondary evidence base, structured interviews were conducted with clinical specialists, procurement leaders, and industry executives to surface practical insights on treatment adoption, patient selection, and operational constraints. These qualitative engagements helped validate trends observed in the literature and clarified how reimbursement and delivery models influence real-world decision-making. The methodology also included an assessment of supply chain and policy developments, focusing on how tariff adjustments and trade policy changes affect manufacturing and distribution strategies.

Data synthesis emphasized triangulation across sources to reduce bias and to highlight convergent conclusions. Limitations were acknowledged where evidence gaps persist, and recommendations were framed to be actionable within the context of identified uncertainties. This methodological approach ensures that the conclusions are grounded in multifaceted evidence and validated practitioner perspectives.

A conclusive synthesis emphasizing how clinical innovation, operational resilience, and localized market strategies will determine success in emphysema treatment

In conclusion, the emphysema treatment landscape is at an inflection point where pharmacological refinements, delivery innovations, and procedural advances converge with evolving payer expectations and regional heterogeneity. Clinical decision-making is increasingly guided by outcomes that matter to patients and health systems, and stakeholders are responding by emphasizing durable maintenance regimens, improved adherence through better devices, and precise surgical selection. These dynamics create opportunities for differentiated therapeutic strategies that combine clinical effectiveness with scalability and economic rationale.

Operationally, trade policy shifts and supply chain pressures underscore the need for manufacturers and distributors to enhance resilience and to incorporate policy sensitivity into commercial planning. Region-specific approaches will be essential, as regulatory frameworks, reimbursement models, and healthcare delivery capacities vary substantially across markets. Competitive success will favor organizations that integrate robust evidence generation, strategic partnerships, and patient-centric product design.

Moving forward, decision-makers should adopt a balanced strategy that prioritizes clinical value, operational agility, and localized market access plans. By aligning innovation with pragmatic execution, stakeholders can improve patient outcomes while navigating the complex commercial and policy landscape that frames contemporary emphysema care.

Table of Contents

1. Preface

• 1.1. Objectives of the Study
• 1.2. Market Segmentation & Coverage
• 1.3. Years Considered for the Study
• 1.4. Currency & Pricing
• 1.5. Language
• 1.6. Stakeholders

2. Research Methodology

3. Executive Summary

4. Market Overview

5. Market Insights

• 5.1. Emergence of personalized inhalation devices with smart monitoring capabilities for emphysema patients
• 5.2. Adoption of regenerative stem cell therapies targeting alveolar tissue repair in emphysema management
• 5.3. Market adoption of next generation long acting bronchodilator combinations with enhanced safety profiles
• 5.4. Integration of cloud connected spirometry and digital health platforms for remote emphysema monitoring
• 5.5. Development of targeted anti inflammatory biologics to mitigate chronic alveolar degradation in emphysema
• 5.6. Collaborations between biotech startups and pulmonary research centers to expedite emphysema drug approvals

6. Cumulative Impact of United States Tariffs 2025

7. Cumulative Impact of Artificial Intelligence 2025

8. Emphysema Treatment Market, by Treatment Type

• 8.1. Pharmacological
  • 8.1.1. Antibiotics
  • 8.1.2. Bronchodilators
  • 8.1.3. Corticosteroids
  • 8.1.4. Mucolytics
• 8.2. Surgical
  • 8.2.1. Bullectomy
  • 8.2.2. Lung Transplantation
  • 8.2.3. Lung Volume Reduction Surgery
  • 8.2.4. Valve Therapy

9. Emphysema Treatment Market, by Drug Class

• 9.1. Anticholinergics
• 9.2. Beta-Agonists
• 9.3. Combination Drugs

10. Emphysema Treatment Market, by Therapy Line

• 10.1. Adjunctive
• 10.2. First-Line
• 10.3. Maintenance
  • 10.3.1. Combination Therapy
  • 10.3.2. Long-Acting Anticholinergics
  • 10.3.3. Long-Acting Beta-Agonists
• 10.4. Rescue
  • 10.4.1. Short-Acting Anticholinergics
  • 10.4.2. Short-Acting Beta-Agonists

11. Emphysema Treatment Market, by Route Of Administration

• 11.1. Inhalation
  • 11.1.1. Dry Powder Inhaler
  • 11.1.2. Metered Dose Inhaler
  • 11.1.3. Nebulizer
  • 11.1.4. Soft Mist Inhaler
• 11.2. Intravenous
  • 11.2.1. Infusion
  • 11.2.2. Injection
• 11.3. Oral
  • 11.3.1. Capsule
  • 11.3.2. Solution
  • 11.3.3. Tablet

12. Emphysema Treatment Market, by Dosage Form

• 12.1. Capsule
• 12.2. Inhaler
• 12.3. Nebulizer
• 12.4. Solution
• 12.5. Tablet

13. Emphysema Treatment Market, by Distribution Channel

• 13.1. Hospital Pharmacy
• 13.2. Online Pharmacy
• 13.3. Retail Pharmacy

14. Emphysema Treatment Market, by Product Type

• 14.1. Brand
• 14.2. Generic

15. Emphysema Treatment Market, by Region

• 15.1. Americas
  • 15.1.1. North America
  • 15.1.2. Latin America
• 15.2. Europe, Middle East & Africa
  • 15.2.1. Europe
  • 15.2.2. Middle East
  • 15.2.3. Africa
• 15.3. Asia-Pacific

16. Emphysema Treatment Market, by Group

• 16.1. ASEAN
• 16.2. GCC
• 16.3. European Union
• 16.4. BRICS
• 16.5. G7
• 16.6. NATO

17. Emphysema Treatment Market, by Country

• 17.1. United States
• 17.2. Canada
• 17.3. Mexico
• 17.4. Brazil
• 17.5. United Kingdom
• 17.6. Germany
• 17.7. France
• 17.8. Russia
• 17.9. Italy
• 17.10. Spain
• 17.11. China
• 17.12. India
• 17.13. Japan
• 17.14. Australia
• 17.15. South Korea

18. Competitive Landscape

• 18.1. Market Share Analysis, 2024
• 18.2. FPNV Positioning Matrix, 2024
• 18.3. Competitive Analysis
  • 18.3.1. GlaxoSmithKline plc
  • 18.3.2. Boehringer Ingelheim International GmbH
  • 18.3.3. AstraZeneca plc
  • 18.3.4. Novartis AG
  • 18.3.5. Teva Pharmaceutical Industries Ltd
  • 18.3.6. Viatris Inc.
  • 18.3.7. Chiesi Farmaceutici S.p.A.
  • 18.3.8. Sunovion Pharmaceuticals Inc.
  • 18.3.9. Sandoz International GmbH
  • 18.3.10. Cipla Limited