의료용 실크 피브로인 시장 보고서 : 동향, 예측 및 경쟁 분석(-2031년)

The future of the global medical silk fibroin market looks promising with opportunities in the hospital, research institution, pharmaceutical company, clinical laboratory, and cosmetic manufacturer markets. The global medical silk fibroin market is expected to grow with a CAGR of 9.2% from 2025 to 2031. The major drivers for this market are the increasing demand for biocompatible materials, the rising use in tissue engineering, and the growing applications in wound healing.

• Lucintel forecasts that, within the product type category, silk fibroin-based hydrogel is expected to witness the highest growth over the forecast period.
• Within the end-use category, hospitals are expected to witness the highest growth.
• In terms of region, APAC is expected to witness the highest growth over the forecast period.

Emerging Trends in the Medical Silk Fibroin Market

The medical silk fibroin market is experiencing a number of emerging trends that are defining its innovation and growth. These trends are indicative of the continuous endeavor to utilize the distinctive characteristics of silk fibroin for innovative medical applications.

• Advanced Silk Fibroin Composites: An important trend is the creation of composite materials with silk fibroin coupled with other biomaterials like hydroxyapatite for bone tissue regeneration or growth factors for better tissue repair. This makes it possible to tailor mechanical strength, bioactivity, and degradation rate for specific medical uses, resulting in more effective and versatile biomaterials.
• Engineering Silk Fibroin for Controlled Drug Release: Scientists are more and more concentrating on structural and property engineering of silk fibroin to develop advanced drug delivery systems. This encompasses encapsulation of drugs into silk fibroin matrices in the form of nanoparticles, hydrogels, or films to provide sustained, localized, or stimulus-triggered release, enhancing therapeutic effect and reducing systemic side effects.
• Growing Applications in 3D Bioprinting: Silk fibroin's good biocompatibility and processability are promoting its use in 3D bioprinting to develop intricate tissue scaffolds and organ models. By printing silk fibroin-based bioinks with high precision, scientists can create structures that resemble the natural tissue microenvironment, which has huge potential for tissue engineering and drug screening.
• Emphasis on Sustainable and Scalable Production Processes: With the increasing need for silk fibroin, there is greater interest in finding sustainable and economical approaches for its extraction, purification, and processing. This involves investigating environmentally friendly degumming processes as well as scaling up production to provide a uniform and low-cost supply of medical-quality silk fibroin.
• Surface Modification for Improved Bioactivity: Surface modification of silk fibroin-based materials to increase cell adhesion, proliferation, and differentiation is an important emerging trend. Methods like chemical functionalization or immobilization of bioactive molecules on silk fibroin surfaces are being investigated to increase the host tissue integration of such materials and their therapeutic efficiency.

All of these trends together are pushing the medical silk fibroin industry towards more sophisticated, effective, and sustainable solutions for a broad array of medical requirements, ranging from regenerative medicine to drug delivery.

Recent Developments in the Medical Silk Fibroin Market

Recent advances in the medical silk fibroin industry reflect the fast development and expanding uses of this extraordinary biomaterial in the healthcare field. Such advancements emphasize the process innovation and technology transfer leading to translational medical applications.

• Injectable Silk Fibroin Hydrogels: Injectable silk fibroin hydrogels are becoming popular for minimally invasive tissue regeneration and drug delivery. The hydrogels are injectable and create a 3D scaffold in situ, which facilitates drug release in a localized fashion or allows cell growth within a certain site, cutting down on the need for surgery.
• Developments in Silk Fibroin Nanofiber Production: Major breakthroughs have occurred in producing silk fibroin nanofibers with a controlled morphology and alignment. The nanofibers can imitate the extracellular matrix and have great potential in the development of applications such as conduits for nerve regeneration and drug delivery systems of high surface area.
• Development of Silk Fibroin-Based Biosensors: Scientists are investigating the application of silk fibroin as a matrix for biosensors because it is biocompatible and can immobilize biomolecules. These biosensors have the possibility of being applied for continuous physiological monitoring or for diagnostics, as wearable and implantable devices.
• Production of Antimicrobial Silk Fibroin Materials: To counter the risk of infection from medical implants and wound dressings, research is aimed at designing silk fibroin materials with built-in antimicrobial properties. This consists of introducing antimicrobial agents or structurally modifying the silk fibroin to prevent bacterial growth.
• Clinical Trial Progress for Silk Fibroin-Based Devices: Some silk fibroin-based medical devices and formulations are in progress in clinical trials. They include silk fibroin scaffolds for bone healing, chronic ulcer wound dressings, and cancer therapy drug delivery systems, reflecting progress towards broader clinical use of these novel materials.

These advances reflect the flexibility of silk fibroin and its expanding potential to respond to urgent challenges in diverse areas of medicine and open doors for innovative treatment protocols and biomedical devices.

Strategic Growth Opportunities in the Medical Silk Fibroin Market

There are significant strategic growth prospects in the medical silk fibroin market across various medical applications, using its exclusive biocompatibility, mechanical strength, and biodegradability. Targeting specific high-growth areas can fuel market growth and innovation.

• Tissue Engineering Scaffolds for Organ Repair and Regeneration: Silk fibroin's processability into porous scaffolds of tunable mechanical properties makes it a good candidate for tissue engineering. Strategic growth can be realized through the development of tailored silk fibroin scaffolds to regenerate specific tissues and organs, such as cartilage, bone, nerve, and skin, to meet the increasing demand for organ repair and replacement therapies.
• Targeted and Sustained Release Drug Delivery Systems: The adaptability of silk fibroin to form nanoparticles, hydrogels, and films opens up great opportunities for creating sophisticated drug delivery systems. Expansion can be achieved through engineering silk fibroin-based carriers for targeted drug delivery to specific tissues or cells and sustained release products that enhance drug effectiveness and compliance of patients.
• Wound Care Dressings for Chronic and Acute Wounds: Silk fibroin's biocompatibility and cell growth-inducing ability render it extremely appropriate for wound care. Strategic growth involves formulating silk fibroin-based dressings, films, and hydrogels that can accelerate healing, inhibit infection, and create a moist environment for chronic and acute wounds, which is on the rise.
• Surgical Sutures and Hemostatic Materials with Improved Properties: Used traditionally in sutures, silk fibroin can also be engineered further to produce surgical sutures with stronger knot strength, lower tissue reactivity, and even drug-eluting properties. Silk fibroin-based materials can also be processed as successful hemostatic agents to suppress bleeding in surgery and trauma, providing a natural and biocompatible option.
• Implantable Medical Devices with Enhanced Biocompatibility: Silk fibroin coatings and composites can be used to improve the biocompatibility of implantable medical devices, minimizing the risk of negative tissue reactions and enhancing device integration. Strategic growth may be attained through collaboration with medical device companies to add silk fibroin to different implants, like cardiovascular stents and orthopedic devices, enhancing their long-term performance and safety.

Leveraging these strategic growth possibilities through concentration on application-specific development, research, and commercialization can greatly increase the medical silk fibroin market and solve vital unmet medical requirements.

Medical Silk Fibroin Market Driver and Challenges

The market for medical silk fibroin is driven by a mix of drivers and challenges that are determining its path and uptake in the healthcare market. It is important for stakeholders to comprehend these factors so that they can effectively navigate the market.

The factors responsible for driving the medical silk fibroin market include:

1. Rising Need for Biocompatible and Biodegradable Materials: The medical sector is increasingly looking for materials that are tolerated well by the body and that naturally degrade after serving their purpose. Silk fibroin's natural biocompatibility and biodegradability are making it a sought-after substitute for synthetic polymers in a number of medical applications, thus boosting demand.

2. Multifunctionality in Material Processing and Fabrication: Silk fibroin may be processed into a variety of forms such as fibers, films, hydrogels, and scaffolds by employing different methods like electrospinning, 3D printing, and solvent casting. This multifunctionality facilitates the fabrication of customized materials and devices for various medical applications.

3. Favorable Mechanical Properties for Biomedical Applications: Silk fibroin exhibits excellent mechanical strength, flexibility, and toughness, which are crucial for many biomedical applications, such as tissue engineering scaffolds and surgical sutures. These properties enable the creation of durable and functional medical devices and materials.

4. Low Immunogenicity and Inflammatory Response: As opposed to certain other biomaterials, silk fibroin tends to elicit low immune response and minimal inflammation on implantation. This desirable biological response improves its compatibility for in vivo medical use and lowers the possibility of complications.

5. Increasing Research and Development Activities: There is ongoing research activity aimed at discovering new applications of silk fibroin, developing improved properties through modification, and optimizing processing methods. Such steady innovation is increasing the range of medical applications of silk fibroin and facilitating market growth.

Challenges in the medical silk fibroin market are:

1. Scalability and Cost of Production: Large-scale production of medical-grade silk fibroin with uniform quality and affordable cost is still a challenge. Reliable and cost-effective technologies for silk degumming, purification, and processing are important for large-scale market application.

2. Regulatory Barriers and Clinical Translation: Similar to other new biomaterials, silk fibroin-derived medical devices and therapies must undergo careful preclinical and clinical testing to prove safety and efficacy and are subject to regulatory review. It can be a lengthy and costly process to negotiate the regulatory pathways and translate successfully into the clinic.

3. Silkworm Source and Processing Variability: Silk fibroin properties may differ based on the species of silkworm, rearing conditions, and processing procedures. Maintaining consistent material performance and quality from different sources and production lots is critical to ensuring dependable medical use.

The market for medical silk fibroin is being strongly driven by the growing need for biocompatible materials, processing flexibility, desirable mechanical characteristics, low immunogenicity, and research activity. Nevertheless, issues concerning scalability of production, regulatory approval, and consistency of the material must be resolved to realize the complete potential of silk fibroin to revolutionize medical treatments and device development. Resolving these issues will lead to expanded clinical use and market expansion.

List of Medical Silk Fibroin Companies

Companies in the market compete on the basis of product quality offered. Major players in this market focus on expanding their manufacturing facilities, R&D investments, infrastructural development, and leverage integration opportunities across the value chain. With these strategies, medical silk fibroin companies cater to increasing demand, ensure competitive effectiveness, develop innovative products & technologies, reduce production costs, and expand their customer base. Some of the medical silk fibroin companies profiled in this report include:

• Seidecosa
• Caresilk
• Seiren
• Dadilan
• LANXESS
• Xi'an ChinWon Biotech
• Xinyuan

Medical Silk Fibroin Market by Segment

The study includes a forecast for the global medical silk fibroin market by product type, application, end use, and region.

Medical Silk Fibroin Market by Product Type [Value from 2019 to 2031]:

• Silk Fibroin-based Hydrogels
• Silk Fibroin Films
• Silk Fibroin Scaffolds
• Silk Fibroin Nanofibers
• Silk Fibroin Microspheres

Medical Silk Fibroin Market by Application [Value from 2019 to 2031]:

• Wound Healing Applications
• Tissue Engineering
• Drug Delivery Systems
• Medical Devices
• Cosmetic & Dermatological Uses
• Others

Medical Silk Fibroin Market by Region [Value from 2019 to 2031]:

• North America
• Europe
• Asia Pacific
• The Rest of the World

Country Wise Outlook for the Medical Silk Fibroin Market

The latest advances in the medical silk fibroin market reflect the growing appreciation of the natural protein's outstanding biocompatibility, biodegradability, and mechanical properties, making it extremely valuable for a wide variety of medical applications. Silk fibroin, a component of silkworm silk, is being researched and utilized in new approaches in different countries for tissue engineering, drug delivery, wound healing, and construction of innovative medical devices. The market is observing a boom in research and development work related to increasing the processability and functionality of silk fibroin to address particular medical requirements, spurred by the increasing demand for sustainable and natural biomaterials in healthcare.

• United States: The US market is witnessing tremendous progress in the application of silk fibroin in regenerative medicine, especially in the creation of scaffolds for tissue engineering and bone regeneration. Efforts are also being made to develop the use of silk fibroin in drug delivery systems for therapeutic controlled and localized release. In addition, silk fibroin-based hydrogels and films are being increasingly sought for wound care because they can stimulate healing and minimize scarring.
• China: As a leading producer of silk, China is actively engaged in researching the medical potential of silk fibroin. Recent advances involve the development of new silk fibroin-based composite materials with improved mechanical properties and bioactivity for bone healing. A focus has also been on the establishment of economical processes for fabricating silk fibroin into different forms, including nanofibers and hydrogels, to extend medical applications.
• Germany: Germany is a leader in biomaterials research, and silk fibroin is becoming increasingly important. Major advances have included the design of silk fibroin scaffolds with engineered pore structures for various tissue regeneration uses. In addition, there is a focus on the degradation mechanism of silk fibroin in vivo in order to maximize its application in implantable medical devices and drug delivery systems.
• India: India, being a country with a long history of silk production, is looking more and more towards the medical applications of silk fibroin. Some recent directions include the creation of silk fibroin-based dressings that are economical and heal wounds quickly. Studies are also investigating the possibility of silk fibroin being used as a carrier for Ayurvedic medicine and other bioactive molecules to be used for localized therapy.
• Japan: Japan is renowned for its material science progress, and silk fibroin is being researched for high-value medical use. New advances have included the production of complex silk fibroin films and coatings for implantable sensors and drug delivery devices. There is also potential for using the unique mechanical properties of silk fibroin in the production of artificial ligaments and tendons.

Features of the Global Medical Silk Fibroin Market

• Market Size Estimates: Medical silk fibroin market size estimation in terms of value ($B).
• Trend and Forecast Analysis: Market trends (2019 to 2024) and forecast (2025 to 2031) by various segments and regions.
• Segmentation Analysis: Medical silk fibroin market size by product type, application, end use, and region in terms of value ($B).
• Regional Analysis: Medical silk fibroin market breakdown by North America, Europe, Asia Pacific, and Rest of the World.
• Growth Opportunities: Analysis of growth opportunities in different product types, applications, end use, and regions for the medical silk fibroin market.
• Strategic Analysis: This includes M&A, new product development, and competitive landscape of the medical silk fibroin market.

Analysis of competitive intensity of the industry based on Porter's Five Forces model.

This report answers following 11 key questions:

• Q.1. What are some of the most promising, high-growth opportunities for the medical silk fibroin market by product type (silk fibroin-based hydrogels, silk fibroin films, silk fibroin scaffolds, silk fibroin nanofibers, and silk fibroin microspheres), application (wound healing applications, tissue engineering, drug delivery systems, medical devices, cosmetic & dermatological uses, and others), end use (hospitals, research institutions, pharmaceutical companies, clinical laboratories, cosmetic manufacturers, and others), and region (North America, Europe, Asia Pacific, and the Rest of the World)?
• Q.2. Which segments will grow at a faster pace and why?
• Q.3. Which region will grow at a faster pace and why?
• Q.4. What are the key factors affecting market dynamics? What are the key challenges and business risks in this market?
• Q.5. What are the business risks and competitive threats in this market?
• Q.6. What are the emerging trends in this market and the reasons behind them?
• Q.7. What are some of the changing demands of customers in the market?
• Q.8. What are the new developments in the market? Which companies are leading these developments?
• Q.9. Who are the major players in this market? What strategic initiatives are key players pursuing for business growth?
• Q.10. What are some of the competing products in this market and how big of a threat do they pose for loss of market share by material or product substitution?
• Q.11. What M&A activity has occurred in the last 5 years and what has its impact been on the industry?

Table of Contents

1. Executive Summary

2. Market Overview

• 2.1 Background and Classifications
• 2.2 Supply Chain

3. Market Trends & Forecast Analysis

• 3.1 Macroeconomic Trends and Forecasts
• 3.2 Industry Drivers and Challenges
• 3.3 PESTLE Analysis
• 3.4 Patent Analysis
• 3.5 Regulatory Environment

4. Global Medical Silk Fibroin Market by Product Type

• 4.1 Overview
• 4.2 Attractiveness Analysis by Product Type
• 4.3 Silk Fibroin-based Hydrogels: Trends and Forecast (2019-2031)
• 4.4 Silk Fibroin Films: Trends and Forecast (2019-2031)
• 4.5 Silk Fibroin Scaffolds: Trends and Forecast (2019-2031)
• 4.6 Silk Fibroin Nanofibers: Trends and Forecast (2019-2031)
• 4.7 Silk Fibroin Microspheres: Trends and Forecast (2019-2031)

5. Global Medical Silk Fibroin Market by Application

• 5.1 Overview
• 5.2 Attractiveness Analysis by Application
• 5.3 Wound Healing Applications: Trends and Forecast (2019-2031)
• 5.4 Tissue Engineering: Trends and Forecast (2019-2031)
• 5.5 Drug Delivery Systems: Trends and Forecast (2019-2031)
• 5.6 Medical Devices: Trends and Forecast (2019-2031)
• 5.7 Cosmetic & Dermatological Uses: Trends and Forecast (2019-2031)
• 5.8 Others: Trends and Forecast (2019-2031)

6. Global Medical Silk Fibroin Market by End Use

• 6.1 Overview
• 6.2 Attractiveness Analysis by End Use
• 6.3 Hospitals: Trends and Forecast (2019-2031)
• 6.4 Research Institutions: Trends and Forecast (2019-2031)
• 6.5 Pharmaceutical Companies: Trends and Forecast (2019-2031)
• 6.6 Clinical Laboratories: Trends and Forecast (2019-2031)
• 6.7 Cosmetic Manufacturers: Trends and Forecast (2019-2031)
• 6.8 Others: Trends and Forecast (2019-2031)

7. Regional Analysis

• 7.1 Overview
• 7.2 Global Medical Silk Fibroin Market by Region

8. North American Medical Silk Fibroin Market

• 8.1 Overview
• 8.2 North American Medical Silk Fibroin Market by Product Type
• 8.3 North American Medical Silk Fibroin Market by End Use
• 8.4 United States Medical Silk Fibroin Market
• 8.5 Mexican Medical Silk Fibroin Market
• 8.6 Canadian Medical Silk Fibroin Market

9. European Medical Silk Fibroin Market

• 9.1 Overview
• 9.2 European Medical Silk Fibroin Market by Product Type
• 9.3 European Medical Silk Fibroin Market by End Use
• 9.4 German Medical Silk Fibroin Market
• 9.5 French Medical Silk Fibroin Market
• 9.6 Spanish Medical Silk Fibroin Market
• 9.7 Italian Medical Silk Fibroin Market
• 9.8 United Kingdom Medical Silk Fibroin Market

10. APAC Medical Silk Fibroin Market

• 10.1 Overview
• 10.2 APAC Medical Silk Fibroin Market by Product Type
• 10.3 APAC Medical Silk Fibroin Market by End Use
• 10.4 Japanese Medical Silk Fibroin Market
• 10.5 Indian Medical Silk Fibroin Market
• 10.6 Chinese Medical Silk Fibroin Market
• 10.7 South Korean Medical Silk Fibroin Market
• 10.8 Indonesian Medical Silk Fibroin Market

11. ROW Medical Silk Fibroin Market

• 11.1 Overview
• 11.2 ROW Medical Silk Fibroin Market by Product Type
• 11.3 ROW Medical Silk Fibroin Market by End Use
• 11.4 Middle Eastern Medical Silk Fibroin Market
• 11.5 South American Medical Silk Fibroin Market
• 11.6 African Medical Silk Fibroin Market

12. Competitor Analysis

• 12.1 Product Portfolio Analysis
• 12.2 Operational Integration
• 12.3 Porter's Five Forces Analysis
  • Competitive Rivalry
  • Bargaining Power of Buyers
  • Bargaining Power of Suppliers
  • Threat of Substitutes
  • Threat of New Entrants
• 12.4 Market Share Analysis

13. Opportunities & Strategic Analysis

• 13.1 Value Chain Analysis
• 13.2 Growth Opportunity Analysis
  • 13.2.1 Growth Opportunities by Product Type
  • 13.2.2 Growth Opportunities by Application
  • 13.2.3 Growth Opportunities by End Use
• 13.3 Emerging Trends in the Global Medical Silk Fibroin Market
• 13.4 Strategic Analysis
  • 13.4.1 New Product Development
  • 13.4.2 Certification and Licensing
  • 13.4.3 Mergers, Acquisitions, Agreements, Collaborations, and Joint Ventures

14. Company Profiles of the Leading Players Across the Value Chain

• 14.1 Competitive Analysis
• 14.2 Seidecosa
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.3 Caresilk
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.4 Seiren
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.5 Dadilan
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.6 LANXESS
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.7 Xi'an ChinWon Biotech
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 14.8 Xinyuan
  • Company Overview
  • Medical Silk Fibroin Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing

15. Appendix

• 15.1 List of Figures
• 15.2 List of Tables
• 15.3 Research Methodology
• 15.4 Disclaimer
• 15.5 Copyright
• 15.6 Abbreviations and Technical Units
• 15.7 About Us
• 15.8 Contact Us