동결 보존용 냉동고 시장 보고서 : 동향, 예측 및 경쟁 분석(-2035년)

Cryopreservation Freezer Market

The future of the global cryopreservation freezer market looks promising with opportunities in the stem cell bank, research & academics institute, biotechnology & pharmaceutical organization, stem cell research lab, and contract research organization markets. The global cryopreservation freezer market is expected to reach an estimated $1233.7 million by 2035 from $762.1 million in 2027 with a CAGR of 6.2% from 2027 to 2035. The major drivers for this market are the increasing demand for long term biological storage, the rising adoption of cell gene therapies, and the growing investments in biobanking infrastructure.

• Lucintel forecasts that, within the type category, control rate freezers is expected to witness the highest growth over the forecast period due to precise control of cooling rates thanks to the use of special materials in the freezer wall.
• Within the application category, stem cell banks is expected to witness the highest growth over the forecast period due to an ideal solution for cryopreservation for the growing stem cell banking industry.
• In terms of regions, APAC is expected to witness the highest growth over the forecast period due to stem cell banking and other related biotechnologies are growing and increasing investments.

Emerging Trends in Cryopreservation Freezer Market

From 2025 to 2027, the freezer market will transition from sale of equipment to leasing of validated cold chain solutions. Increasing demands for storage solutions for cell and gene therapies and other biological products have led to the investment and development of cold chain infrastructure. According to Lucintel, alongside these market dynamics, there will be a focus on reducing the cost of ownership and improving monitoring and control of cold chain solutions.

• Automation: There will be increasing preference towards automated retrieval and control of biobank inventories. Automated storage systems will increase biobank sample density and reduce laboratory personnel's exposure to cold. Unattended biobank storage will be required by regulatory bodies and will be preferred in the market.
• Sustainability: There will be a shift towards usage of natural working fluids in biobank refrigeration systems, especially in the European market. New biobank units will be 30% more efficient than the existing units. The cost of energy and carbon impacts of biobank systems will be the key drivers of the replacements of biobank refrigeration units.
• Digital Monitoring: Cloud-based and real-time monitoring of sample storage will be implemented in laboratories. Continuous sample storage unit temperature monitoring will allow remote sample storage unit management and control. Continuous, real time sample storage unit temperature monitoring will be required and preferred by biobank customers.
• Regional Supply Diversification: As biopharmaceutical and cell and gene therapy manufacturing will be decentralized, so will cold chain storage solutions. Biobanks will be required to provide cold storage solutions with short response times.
• Advanced Insulation: Most advanced insulation consists of vacuum panels and phase-change materials (PCMs) and is found in the best freezers. Improved door seals are also found on better freezers. Freezer manufacturers are trying to increase how long their freezers can hold a temperature in the event of a power outage. Freezer manufacturers will strive to increase the time their freezers can be powered down by improving the insulation in their freezers. Due to improved insulation, it will be possible to decentralize biobanking in the next 5 years. Decentralized biobanking means it will not be necessary to rely on oversized back up systems to support biobanking.

The increased rate of biomedical research and resulting growth in biological samples will keep the demand for biobanking and freezer systems strong. The expectation of biobanking customers is changing faster than the volume of biobanking units sold. Customers expect their biobanking units to have integrated control systems and be interconnected to other biobanking units. Continuous operation and energy conservation should be built into the biobanking systems. Biobanking systems of the future will be engineered using combinations of mechanical, electrical, controls and software engineering. Units will be purchased based on the value of the samples to be stored. Units will be engineered to ensure sample integrity.

Recent Developments in the Cryopreservation Freezer Market

Faster replacement cycles of cryopreservation freezers with more specialized features is expected in the years 2025-2027. Funding and advancements in the fields of cell and gene therapies, along with additional research, have led to an increase in the requirement for biobanking and storage capacity. It is expected that the primary freezer purchases will be influenced by energy efficiency and other operational costs as well as alarm connectivity and temperature uniformity.

• Facility Expansion: Thermo Fisher Scientific's 2025 expansion to provide bioproduction customers the ability to store product at temperatures below -150°C further strengthens their competitive position, as the commercial manufacture of cell and gene therapies continues to grow (April 2025).
• Product Refinement: PHCbi released an improved configuration of their ultra-low temperature freezers in 2025. The new configuration included enhancements to reduce the freezer's energy use and incorporated remote alarms. The new features are expected to influence freezer replacements in the next 3-5 years.
• Increased Partnership: BioLife Solutions and a regional cell therapy network have extended their partnership to provide end-to-end solutions for cryogenic storage (Sept 2025). With the adoption of standardized software and consumables, companies will need to provide integrated solutions to be competitive in the market.
• Industry Consolidation: In 2025, the European Union granted several regulatory approvals for advanced therapies including products requiring controlled cryogenic storage. Each authorization served as an endorsement for a specific product and increased the demand for associated validated storage and transport solutions.
• New Investments: In 2025, biobanking and reproductive health companies in China raised over $100 million. Increased investment led to rapid improvements in biobanking and research infrastructure and heightened competition among biobank equipment and service providers.

From 2020 to 2025, the market primarily relied on replacement demands. Between 2025 and 2030, regulated capacity and quality improvements will drive the market. The use of freezers with monitors and backup systems will be positive for the market. Conventional freezers will continue to be offered and deployed based on price.

Strategic Growth Opportunities in the Cryopreservation Freezer Market

The increasing maturity of cell and gene therapy drug pipelines, along with the expansion of biobanks and outsourcing by pharmaceutical companies, are expected to create opportunities for the cryopreservation freezer market. In the 2024-2026 period, particularly stringent sample storage requirements and the shift to distributed/home-based drug-product manufacturing will require sophisticated, integrated, and energy-efficient systems. According to Lucintel, these systems will find end-use in markets outside traditional laboratory storage.

• Cell and Gene Therapy: The storage and distribution of living cellular and viral vectors will primarily drive the need for ultra-low temperature (ULT) biomedical freezers. As of January, 2025, the U.S. Food and Drug Administration (FDA) had approved 30 cell and gene therapies. Thriving and growing markets of these products will increase the demand for ULT freezers, biomedical cold chain logistics, and storage over the next decade.
• Biobanking: Freezers used in population-based biobanking will need to store large numbers of samples over long periods of time. In March 2025, the UK Biobank reported they had samples from 500,000 research participants. Increasing numbers of similar initiatives will potentially create a regular and reoccurring need for automated storage and retrieval systems (ASRS) over the next 5-years.
• Emerging Market Healthcare: Suppliers can market their products to hospitals and research and fertility centers in India, Southeast Asia and the Middle East. India dedicated about ₹99,858 crore (USD 12.5 billion) to its health and family welfare sector in its 2025 Budget. Cheaper prices of medical devices will not determine their adoption potential. Rather, the strength of local service and financing networks will play a larger role.
• Energy Efficient Premium System: Rising electricity costs and the need for sustainability will lead to the increased adoption of low-energy compressors, designs incorporating vacuum insulation and refrigerant thermo-recovery. Products conforming to the EU's revised F-Gas Regulations will take over the market during the refresh cycles.
• Digital Monitoring and Aftermarket Services: The after-sales potential of equipment integrating digital monitoring and control systems will remain a major source of revenue. Continued requirements for electronic records and workflow documentation will provide a recurring and predictable revenue stream for equipment vendors.

Rising concern for sustainability will lead to the adoption of medical equipment integrating low-energy and low-carbon-footprint refrigerants. The most successful medical equipment companies will use their capabilities to guarantee the reliability and sustainability of products throughout their life cycle.

Cryopreservation Freezer Market Drivers and Challenges

Cryopreservation freezers are expected to gain popularity with advancements in technology and increases in cell and gene therapy and in related investments. Additionally, increasing regulations and demands in the industry are expected to provide growth opportunities in this market. The need for safe and efficient ultra-low temperature storage is expected to increase in the future. Lucintel expects that long-term success for companies operating in this market would depend on their level of investment in research and development. Although there are expectations for growth in this market, high costs, large size, and complex regulation of these freezers are expected to restrain the market.

The factors responsible for driving this market include:

• Expanding Biobanking Demand: Increased demand for long term storage of biological samples. These samples include stem cells, blood and tissue, embryos, and genetic materials. These samples are used for various scientific and medical research and facilities are funded by the government to establish such long term storage resources. The National Institutes of Health, United States of America, is funding several biomedical research projects, which in turn has increased the requirement for storage and handling of bio-samples. It is expected that in the next 3 to 5 years the market for such samples and storage would further increase due to the growth of research in the field of regenerative medicine.
• Growth of Cell and Gene Therapies: Increased development of cell and gene therapies has created a need for storage systems to preserve biological integrity during manufacturing and transport. As of June 2025, the US FDA had listed 20 cell and gene therapies, indicating interest in this field. In the next 3-5 years, the clinical pipeline will require the manufacture and transport of biological materials using industry equipment and techniques, including specialized equipment for freezing at controlled rates, and vapor-phase and other digital traceability and backup storage.
• Advancements in Technology: Freezers can have automated controls for temperature and other parameters. Freezers can also have data loggers and be equipped with other features that enable predictive failure. Freezers can have improvements in insulation. Freezers can be connected to the internet, and, along with other lab equipment, be monitored continuously. Equipment can be integrated to enable processes, and alert personnel to failures before they occur. Improved equipment, along with other processes, can create a more automated laboratory and enhance control over laboratory operations and sample integrity.
• Regulatory and Quality Requirements: A primary driver for the move away from simple storage units has been the evolution of regulatory requirements. New requirements focused on the validation of storage systems, qualification of storage unit equipment, and the documentation of temperature excursions have created a heightened emphasis on system compliance. The expectations for the quality of pharmaceutical products have created an increased demand for systems that are designed to maintain storage conditions and ensure the integrity of records and data. Over the next three to five years, the focus will be on the storage of temperature sensitive pharmaceutical products. Many states have begun to award new contracts for the storage of temperature sensitive pharmaceutical products. New contracts have created an opportunity for suppliers to provide validation and service contracts for storage systems. The demand will be focused on systems that meet specified requirements for alarms, calibration, and access.
• Energy and Manufacturing Efficiency: Continued research and development of systems that maintain temperature stability have allowed systems to become smaller, more reliable and easier to use. Significant advancements in manufacturing and design of systems that utilize different refrigerants have allowed systems to be manufactured faster and at a reduced cost. A focus on energy and efficiency in the design of systems has caused a 20% reduction in the power consumption of systems. Reduced size and weight of systems have allowed more flexibility in the design of laboratory equipment. Advanced systems have allowed for real time, accurate record keeping.

The challenges facing this market include:

• High Acquisition and Operating Costs: The costs associated with acquiring and operating a cryopreservation system are high. In the Feb. 2025, survey of laboratory capital budgets, many respondents reported deferred equipment purchases, including freezers, due to a lack of funding. It is expected that in the next 3-5 years, costs associated with operating free-standing laboratories such as community hospitals and biotech start-ups, will hinder the purchase and utilization of these systems. Freezer manufacturers and suppliers need to look at ways to reduce costs, and provide more service agreements to subsidize the purchase of more expensive, advanced systems.
• Energy Use and Environment: The usage of immersion cooling to decrease energy consumption of freezers is gaining popularity. The use of advanced insulation and natural refrigerants will help reduce environmental impact. Equipment manufacturers need to develop more advanced, energy efficient compressors.
• Operational Risks and Constraints: Biological materials are at risk when the power goes out. There is inadequate ventilation for some fume hoods, and some laboratory personnel are poor responders to alarms and emergencies. There is a potential loss of irreplaceable biological resources due to insufficiently trained personnel and/or inadequate backup power for biomedical cold storage. In August 2025, laboratory assessments conducted by the U.S. National Science Foundation indicated that 24 hours of uninterrupted power would be necessary to safeguard critical research. It is expected that within the next 3 to 5 years, construction of laboratory facilities will require, in addition to other features, redundant freezers, standby power, and trained personnel. There are significant gaps in the electrical and service infrastructure of some countries, and implementing these measures in these locales may increase the costs of laboratory construction.

Innovations in design, digital controls, regulatory law, and energy efficiency improved the performance of liquid storage systems, contributing to the growth of the market for cryopreservation freezers. Growing markets for biopharmaceuticals and cell and gene therapies, coupled with the growth of biomedical research and contract manufacturing, drive the demand for storage systems to safely retain biopharmaceutical intermediates and other research materials. Market players that integrate these aforementioned features in their offerings and provide financing will thrive.

List of Cryopreservation Freezer Market Companies

Companies in the market compete on the basis of product quality offered. Major players in this market focus on expanding their manufacturing facilities, R&D investments, infrastructural development, and leverage integration opportunities across the value chain. Through these strategies cryopreservation freezer market companies cater increasing demand, ensure competitive effectiveness, develop innovative products & technologies, reduce production costs, and expand their customer base. Some of the cryopreservation freezer market companies profiled in this report include-

• Custom Biogenic System
• Merck KGaA
• Asymptote Limited
• Thermo Fisher Scientific Inc
• Haimen United Laboratory Equipment Development Co
• Linde LLC
• Cryogenic Control

Cryopreservation Freezer Market by Segment

The study includes a forecast for the global cryopreservation freezer market by type, application, and region.

Cryopreservation Freezer Market by Type [Value ($M) from 2019 to 2035]:

• Control Rate Freezers
• Step Down Freezing
• Single SBS Plate Model
• Double SBS Plate Model

Cryopreservation Freezer Market by Application [Value ($M) from 2019 to 2035]:

• Stem Cells Banks
• Research & Academics Institute
• Biotechnology & Pharmaceutical Organization
• Stem Cell Research Lab
• Contract Research Organizations
• Others

Cryopreservation Freezer Market by Region [Value ($M) from 2019 to 2035]:

• North America
• Europe
• Asia Pacific
• The Rest of the World

Country Wise Outlook for the Cryopreservation Freezer Market

The biopharmaceutical and cell therapy industries' expansion and improvement in cold chain storage standards has led to significant changes in the cryopreservation market. The period from 2025 to 2027 is expected to see further improvements and expansion to meet the demands of various long-range supply chains. According to Lucintel, these trends and forecasts have positive outlooks for the market and do not rely on any one primary driver.

• United States: Between February 2025 and April 2025, Thermo Fisher Scientific, Inc. and T forcing of the floor, expanded their cell and gene therapy manufacturing facilities in New Jersey and Massachusetts, respectively. These investments underscore rising domestic demand for large-scale manufacturing and storage of ultralow temperature cell and gene therapies.
• China: In March 2025, the China Food and Drug Administration (the former China National Medical Products Administration) continued reviewing a series of clinical-trial applications for Chinese cell-therapy products. Simultaneously, leading Chinese biopharmaceutical companies built or expanded GMP storage and transport facilities. The new policies and regulatory frameworks relating to cell therapy will increase the number of clinical-trial products, thus creating a greater demand for validated medical freezers.
• Germany: Sartorius's 100 million Euro investment to construct new bioprocessing and lab equipment manufacturing facilities in Germany will boost their regional and potentially global storage systems manufacturing capacity. Additional manufacturing capacity for bioprocessing storage systems is expected to improve biopharmaceutical production and supply across Europe.
• India: In January 2025, the Indian Department of Biotechnology further implemented the National Biopharma Mission for the production of veterinary biologics, therapeutic vaccines and advanced therapy products. This project will increase the demand for validated sample, vaccine and cell bank storage.
• Japan: PHC Corporation expanded their biomedical refrigerator and biobank equipment line in April 2025. The VIP ECO Series Ultra Low Temperature Freezers with a storage temperature of -86 °C target hospitals, universities and pharmaceutical companies in Japan.

Features of the Global Cryopreservation Freezer Market

• Market Size Estimates: cryopreservation freezer market size estimation in terms of value ($B).
• Trend and Forecast Analysis: Market trends (2019 to 2026) and forecast (2027 to 2035) by various segments and regions.
• Segmentation Analysis: cryopreservation freezer market size by type, application, and region in terms of value ($B).
• Regional Analysis: cryopreservation freezer market breakdown by North America, Europe, Asia Pacific, and Rest of the World.
• Growth Opportunities: Analysis of growth opportunities in different types, applications, and regions for the cryopreservation freezer market.
• Strategic Analysis: This includes M&A, new product development, and competitive landscape of the cryopreservation freezer market.

Analysis of competitive intensity of the industry based on Porter's Five Forces model.

If you are looking to expand your business in this or adjacent markets, then contact us. We have done hundreds of strategic consulting projects in market entry, opportunity screening, due diligence, supply chain analysis, M & A, and more.

This report answers following 11 key questions:

• Q.1. What are some of the most promising, high-growth opportunities for the cryopreservation freezer market by type (control rate freezers, step down freezing, single SBS plate model, and double SBS plate model), application (stem cells banks, research & academics institute, biotechnology & pharmaceutical organization, stem cell research lab, contract research organizations, and others), and region (North America, Europe, Asia Pacific, and the Rest of the World)?
• Q.2. Which segments will grow at a faster pace and why?
• Q.3. Which region will grow at a faster pace and why?
• Q.4. What are the key factors affecting market dynamics? What are the key challenges and business risks in this market?
• Q.5. What are the business risks and competitive threats in this market?
• Q.6. What are the emerging trends in this market and the reasons behind them?
• Q.7. What are some of the changing demands of customers in the market?
• Q.8. What are the new developments in the market? Which companies are leading these developments?
• Q.9. Who are the major players in this market? What strategic initiatives are key players pursuing for business growth?
• Q.10. What are some of the competing products in this market and how big of a threat do they pose for loss of market share by material or product substitution?
• Q.11. What M&A activity has occurred in the last 8 years and what has its impact been on the industry?

Table of Contents

1. Executive Summary

2. Market Overview

• 2.1 Background and Classifications
• 2.2 Supply Chain

3. Market Trends & Forecast Analysis

• 3.1 Macroeconomic Trends and Forecasts
• 3.2 Industry Drivers and Challenges
• 3.3 PESTLE Analysis
• 3.4 Patent Analysis
• 3.5 Regulatory Environment

4. Global Cryopreservation Freezer Market by Type

• 4.1 Overview
• 4.2 Attractiveness Analysis by Type
• 4.3 Control Rate Freezers : Trends and Forecast 2019 to 2035
• 4.4 Step Down Freezing : Trends and Forecast 2019 to 2035
• 4.5 Single SBS Plate Model : Trends and Forecast 2019 to 2035
• 4.6 Double SBS Plate Model : Trends and Forecast 2019 to 2035

5. Global Cryopreservation Freezer Market by Application

• 5.1 Overview
• 5.2 Attractiveness Analysis by Application
• 5.3 Stem Cells Banks : Trends and Forecast 2019 to 2035
• 5.4 Research & Academics Institute : Trends and Forecast 2019 to 2035
• 5.5 Biotechnology & Pharmaceutical Organization : Trends and Forecast 2019 to 2035
• 5.6 Stem Cell Research Lab : Trends and Forecast 2019 to 2035
• 5.7 Contract Research Organizations : Trends and Forecast 2019 to 2035
• 5.8 Others : Trends and Forecast 2019 to 2035

6. Regional Analysis

• 6.1 Overview
• 6.2 Global Cryopreservation Freezer Market by Region

7. North American Cryopreservation Freezer Market

• 7.1 Overview
• 7.2 North American Cryopreservation Freezer Market by Type
• 7.3 North American Cryopreservation Freezer Market by Application
• 7.4 The United States Cryopreservation Freezer Market
• 7.5 Canadian Cryopreservation Freezer Market
• 7.6 Mexican Cryopreservation Freezer Market

8. European Cryopreservation Freezer Market

• 8.1 Overview
• 8.2 European Cryopreservation Freezer Market by Type
• 8.3 European Cryopreservation Freezer Market by Application
• 8.4 German Cryopreservation Freezer Market
• 8.5 French Cryopreservation Freezer Market
• 8.6 Italian Cryopreservation Freezer Market
• 8.7 Spanish Cryopreservation Freezer Market
• 8.8 The United Kingdom Cryopreservation Freezer Market

9. APAC Cryopreservation Freezer Market

• 9.1 Overview
• 9.2 APAC Cryopreservation Freezer Market by Type
• 9.3 APAC Cryopreservation Freezer Market by Application
• 9.4 Chinese Cryopreservation Freezer Market
• 9.5 Indian Cryopreservation Freezer Market
• 9.6 Japanese Cryopreservation Freezer Market
• 9.7 South Korean Cryopreservation Freezer Market
• 9.8 Indonesian Cryopreservation Freezer Market

10. ROW Cryopreservation Freezer Market

• 10.1 Overview
• 10.2 ROW Cryopreservation Freezer Market by Type
• 10.3 ROW Cryopreservation Freezer Market by Application
• 10.4 Middle Eastern Cryopreservation Freezer Market
• 10.5 South American Cryopreservation Freezer Market
• 10.6 African Cryopreservation Freezer Market

11. Competitor Analysis

• 11.1 Product Portfolio Analysis
• 11.2 Operational Integration
• 11.3 Porter's Five Forces Analysis
  • Competitive Rivalry
  • Bargaining Power of Buyers
  • Bargaining Power of Suppliers
  • Threat of Substitutes
  • Threat of New Entrants
• 11.4 Market Share Analysis

12. Opportunities & Strategic Analysis

• 12.1 Value Chain Analysis
• 12.2 Growth Opportunity Analysis
  • 12.2.1 Growth Opportunity by Type
  • 12.2.2 Growth Opportunity by Application
• 12.3 Emerging Trends in the Global Cryopreservation Freezer Market
• 12.4 Strategic Analysis
  • 12.4.1 New Product Development
  • 12.4.2 Certification and Licensing
  • 12.4.3 Mergers, Acquisitions, Agreements, Collaborations, and Joint Ventures

13. Company Profiles of the Leading Players Across the Value Chain

• 13.1 Competitive Analysis Overview
• 13.2 Custom Biogenic System
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.3 Merck KGaA
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.4 Asymptote Limited
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.5 Thermo Fisher Scientific Inc
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.6 Haimen United Laboratory Equipment Development Co
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.7 Linde LLC
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.8 Cryogenic Control
  • Company Overview
  • Cryopreservation Freezer Market Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing

14. Appendix

• 14.1 List of Figures
• 14.2 List of Tables
• 14.3 Research Methodology
• 14.4 Disclaimer
• 14.5 Copyright
• 14.6 Abbreviations and Technical Units
• 14.7 About Us
• 14.8 Contact Us