The global bleeding disorders market size is expected to reach USD 27.49 billion by 2032, according to a new study by Polaris Market Research. The report "Bleeding Disorders Market Share, Size, Trends, Industry Analysis Report, By Type (Hemophilia A, Hemophilia B, Von Willebrand Diseases); By Drug Class; By Region; Segment Forecast, 2023 - 2032" gives a detailed insight into current market dynamics and provides analysis on future market growth.
The most prevalent kind of hemophilia is hemophilia A. It occurs when there is insufficient clotting factor 8. According to the Centres for Disease Control and Prevention (CDC), hemophilia A affects roughly 10 in every 100,000 persons in the United States. When clotting factor 9 levels are insufficient, hemophilia B develops. According to the CDC, hemophilia B affects roughly 3 in 100,000 Americans. This is driving the growth and demand for the bleeding disorders market in coming years.
The increasing prevalence of hemophilia A, greater awareness and screening for the disease, advances in new therapies, and the longer life expectancy of patients with the disease are all contributing factors to the growth of the bleeding disorders market. According to Statista, Hemophilia A affected 185,318 persons globally in 2021, while another 17,951 people had various platelet diseases. As more patients are diagnosed with hemophilia A and B, the demand for clotting factor replacement therapy increases, which fuels the growth of the market.
Bleeding disorders, such as hemophilia and von Willebrand disease, are characterized by a deficiency or dysfunction of clotting factors in the blood. Patients with bleeding disorders require regular infusions of clotting factor replacement therapy to prevent or control bleeding episodes. These clotting factors are primarily derived from donated blood and plasma. In order to produce these clotting factors, donor blood and plasma must be available.
Due to the rising prevalence of bleeding diseases, there is an increase in need for blood donations as well as clotting factor replacement therapy. According to the World Health Organization, 119 nations have recorded an increase in voluntary unpaid blood donations of 10.7 million from 2008 to 2018. This will create a wide range of opportunities for the growth of the bleeding disorders market.
HBV causes 600,000 to 1.2 million fatalities annually, with 15-40% of infected patients developing fatal liver conditions (cirrhosis, liver failure, and hepatocellular carcinoma). Patients with liver cirrhosis and HCC are at an increased risk of developing bleeding disorders due to the decreased production of clotting factors by the liver. As a result, the demand for clotting factor replacement therapy is high among these patients, which fuels the growth of the market.
Bleeding Disorders Market Report Highlights
Hemophilia A Type is anticipated to grow due to the increasing prevalence of hemophilia A and rising demand for novel therapies.
Recombinant Coagulation Factor Concentrates segment accounted for the higher growth rate owing to the growing demand for prophylaxis and advancements in manufacturing technology.
Asia Pacific is expected to grow at a significant growth rate owing to the increasing prevalence of bleeding disorders and investments in research & development.
The global players include: Novo Nordisk, Bayer, Baxter International, Alnylam Pharmaceuticals, Pfizer, Xenetic Biosciences, Bristol, Sanofi, Amgen, Janssen, and Bioverativ Inc.
Polaris Market Research has segmented the bleeding disorders market report based on type, drug class and region:
Bleeding Disorders, Type Outlook (Revenue - USD Billion, 2019 - 2032)
- Hemophilia A
- Hemophilia B
- Von Willebrand Diseases
Bleeding Disorders, Drug Class Outlook (Revenue - USD Billion, 2019 - 2032)
- Plasma Derived Coagulation Factor Concentrates
- Recombinant Derived Coagulation Factor
- Desmopressin
- Antifibrinolytics
- Fibrin Sealants
Bleeding Disorders, Regional Outlook (Revenue - USD Billion, 2019 - 2032)
- North America
- U.S.
- Canada
- Europe
- Germany
- UK
- France
- Italy
- Spain
- Russia
- Netherlands
- Asia Pacific
- China
- India
- Japan
- South Korea
- Indonesia
- Malaysia
- Latin America
- Argentina
- Brazil
- Mexico
- Middle East & Africa
- UAE
- Saudi Arabia
- Israel
- South Africa
Table of Contents
1. Introduction
- 1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
- 1.2. Stakeholders
2. Executive Summary
3. Research Methodology
- 3.1. Overview
- 3.2. Data Sources
- 3.2.1. Primary Sources
- 3.2.2. Secondary Sources
4. Global Bleeding Disorders Market Insights
- 4.1. Bleeding Disorders Market - Industry Snapshot
- 4.2. Bleeding Disorders Market Dynamics
- 4.2.1. Drivers and Opportunities
- 4.2.1.1. Rise in prevalence of hemophilia
- 4.2.1.2. Rise in awareness about bleeding disorders in developing countries
- 4.2.2. Restraints and Challenges
- 4.2.2.1. High cost of bleeding disorders treatments
- 4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
- 4.4. PESTLE Analysis
- 4.5. Bleeding Disorders Industry trends
- 4.6. Value Chain Analysis
- 4.7. COVID-19 Impact Analysis
5. Global Bleeding Disorders Market, by Type
- 5.1. Key Findings
- 5.2. Introduction
- 5.2.1. Global Bleeding Disorders, by Type, 2019-2032 (USD Billion)
- 5.3. Hemophilia A
- 5.3.1. Global Bleeding Disorders Market, by Hemophilia A, by Region, 2019-2032 (USD Billion)
- 5.4. Hemophilia B
- 5.4.1. Global Bleeding Disorders Market, by Hemophilia B, by Region, 2019-2032 (USD Billion)
- 5.5. Von Willebrand Diseases
- 5.5.1. Global Bleeding Disorders Market, by Von Willebrand Diseases, by Region, 2019-2032 (USD Billion)
6. Global Bleeding Disorders Market, by Drug Class
- 6.1. Key Findings
- 6.2. Introduction
- 6.2.1. Global Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 6.3. Plasma Derived Coagulation Factor Concentrates
- 6.3.1. Global Bleeding Disorders Market, by Plasma Derived Coagulation Factor Concentrates, by Region, 2019-2032 (USD Billion)
- 6.4. Recombinant Derived Coagulation Factor
- 6.4.1. Global Bleeding Disorders Market, by Recombinant Derived Coagulation Factor, by Region, 2019-2032 (USD Billion)
- 6.5. Desmopressin
- 6.5.1. Global Bleeding Disorders Market, by Electric, by Region, 2019-2032 (USD Billion)
- 6.6. Antifibrinolytics
- 6.6.1. Global Bleeding Disorders Market, by Antifibrinolytics, by Region, 2019-2032 (USD Billion)
- 6.7. Fibrin Sealants
- 6.7.1. Global Bleeding Disorders Market, by Fibrin Sealants, by Region, 2019-2032 (USD Billion)
7. Global Bleeding Disorders Market, by Geography
- 7.1. Key findings
- 7.2. Introduction
- 7.2.1. Bleeding Disorders Market Assessment, By Geography, 2019-2032 (USD Billion)
- 7.3. Bleeding Disorders Market - North America
- 7.3.1. North America: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.3.2. North America: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.3.3. Bleeding Disorders Market - U.S.
- 7.3.3.1. U.S.: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.3.3.2. U.S.: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.3.4. Bleeding Disorders Market - Canada
- 7.3.4.1. Canada: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.3.4.2. Canada: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4. Bleeding Disorders Market - Europe
- 7.4.1. Europe: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.2. Europe: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.3. Bleeding Disorders Market - UK
- 7.4.3.1. UK: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.3.2. UK: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.4. Bleeding Disorders Market - France
- 7.4.4.1. France: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.4.2. France: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.5. Bleeding Disorders Market - Germany
- 7.4.5.1. Germany: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.5.2. Germany: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.6. Bleeding Disorders Market - Italy
- 7.4.6.1. Italy: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.6.2. Italy: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.7. Bleeding Disorders Market - Spain
- 7.4.7.1. Spain: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.7.2. Spain: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.8. Bleeding Disorders Market - Netherlands
- 7.4.8.1. Netherlands: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.8.2. Netherlands: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.4.9. Bleeding Disorders Market - Russia
- 7.4.9.1. Russia: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.4.9.2. Russia: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5. Bleeding Disorders Market - Asia Pacific
- 7.5.1. Asia Pacific: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.2. Asia Pacific: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.3. Bleeding Disorders Market - China
- 7.5.3.1. China: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.3.2. China: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.4. Bleeding Disorders Market - India
- 7.5.4.1. India: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.4.2. India: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.5. Bleeding Disorders Market - Malaysia
- 7.5.5.1. Malaysia: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.5.2. Malaysia: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.6. Bleeding Disorders Market - Japan
- 7.5.6.1. Japan: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.6.2. Japan: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.7. Bleeding Disorders Market - Indonesia
- 7.5.7.1. Indonesia: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.7.2. Indonesia: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.5.8. Bleeding Disorders Market - South Korea
- 7.5.8.1. South Korea: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.5.8.2. South Korea: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.6. Bleeding Disorders Market - Middle East & Africa
- 7.6.1. Middle East & Africa: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.6.2. Middle East & Africa: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.6.3. Bleeding Disorders Market - Saudi Arabia
- 7.6.3.1. Saudi Arabia: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.6.3.2. Saudi Arabia: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.6.4. Bleeding Disorders Market - UAE
- 7.6.4.1. UAE: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.6.4.2. UAE: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.6.5. Bleeding Disorders Market - Israel
- 7.6.5.1. Israel: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.6.5.2. Israel: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.6.6. Bleeding Disorders Market - South Africa
- 7.6.6.1. South Africa: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.6.6.2. South Africa: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.7. Bleeding Disorders Market - Latin America
- 7.7.1. Latin America: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.7.2. Latin America: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.7.3. Bleeding Disorders Market - Mexico
- 7.7.3.1. Mexico: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.7.3.2. Mexico: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.7.4. Bleeding Disorders Market - Brazil
- 7.7.4.1. Brazil: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.7.4.2. Brazil: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
- 7.7.5. Bleeding Disorders Market - Argentina
- 7.7.5.1. Argentina: Bleeding Disorders Market, by Drug Class, 2019-2032 (USD Billion)
- 7.7.5.2. Argentina: Bleeding Disorders Market, by Type, 2019-2032 (USD Billion)
8. Competitive Landscape
- 8.1. Expansion and Acquisition Analysis
- 8.1.1. Expansion
- 8.1.2. Acquisitions
- 8.2. Partnerships/Collaborations/Agreements/Exhibitions
9. Company Profiles
- 9.1. Novo Nordisk
- 9.1.1. Company Overview
- 9.1.2. Financial Performance
- 9.1.3. Product Benchmarking
- 9.1.4. Recent Development
- 9.2. Bayer
- 9.2.1. Company Overview
- 9.2.2. Financial Performance
- 9.2.3. Product Benchmarking
- 9.2.4. Recent Development
- 9.3. Baxter
- 9.3.1. Company Overview
- 9.3.2. Financial Performance
- 9.3.3. Product Benchmarking
- 9.3.4. Recent Development
- 9.4. Alnylam Pharmaceuticals
- 9.4.1. Company Overview
- 9.4.2. Financial Performance
- 9.4.3. Product Benchmarking
- 9.4.4. Recent Development
- 9.5. Xenetic Biosciences
- 9.5.1. Company Overview
- 9.5.2. Financial Performance
- 9.5.3. Product Benchmarking
- 9.5.4. Recent Development
- 9.6. Bristol-Myers
- 9.6.1. Company Overview
- 9.6.2. Financial Performance
- 9.6.3. Product Benchmarking
- 9.6.4. Recent Development
- 9.7. Sanofi
- 9.7.1. Company Overview
- 9.7.2. Financial Performance
- 9.7.3. Product Benchmarking
- 9.7.4. Recent Development
- 9.8. Amgen
- 9.8.1. Company Overview
- 9.8.2. Financial Performance
- 9.8.3. Product Benchmarking
- 9.8.4. Recent Development
- 9.9. Janssen
- 9.9.1. Company Overview
- 9.9.2. Financial Performance
- 9.9.3. Product Benchmarking
- 9.9.4. Recent Development
- 9.10. Bioverativ Inc
- 9.10.1. Company Overview
- 9.10.2. Financial Performance
- 9.10.3. Product Benchmarking
- 9.10.4. Recent Development