세계의 무혈청 배지 시장 : 시장 점유율과 순위, 전체 판매 및 수요 예측(2025-2031년)

The global market for Serum-Free Media was estimated to be worth US$ 1464 million in 2024 and is forecast to a readjusted size of US$ 3140 million by 2031 with a CAGR of 11.4% during the forecast period 2025-2031.

This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on Serum-Free Media cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply chain reconfigurations.

Serum-Free Media (SFM) is a class of cell culture media designed without the use of animal serum, intended for in vitro cultivation of mammalian, insect, stem, and other cell types. Unlike traditional media supplemented with fetal bovine serum (FBS), SFM offers a precisely formulated composition of amino acids, vitamins, inorganic salts, hormones, growth factors, and trace elements, providing a stable and reproducible environment for cell growth while eliminating the variability and potential pathogen risks associated with serum. Its high standardization and controllability make SFM a core material in biopharmaceuticals, cell and gene therapy, vaccine development, monoclonal antibody production, and large-scale industrial cell culture. In recent years, driven by the rapid growth of cell therapy and recombinant protein drugs, the SFM market has shifted from laboratory use to industrial-scale applications, establishing itself as a strategically critical link in the biopharmaceutical value chain.In 2024, global Serum-Free Media production reached approximately 34.5 million L, with an average global market price of around US$ 42.43 per L.

The global biopharmaceutical industry's continuous expansion and increased investment in innovative drug R&D have created strong momentum for the serum-free media (SFM) market. The commercialization of advanced therapies such as cell therapy, gene editing, vaccine manufacturing, and CAR-T is driving a surge in demand for high-quality, traceable, and animal-component-free culture systems, accelerating the shift from serum-based media to SFM. Regulatory agencies (FDA, EMA, NMPA) are raising standards for product consistency and safety, further highlighting the strategic importance of SFM. Global leaders like Thermo Fisher, Cytiva, and Merck KGaA are expanding their SFM portfolios, while Chinese companies such as OpM, Thermo Fisher China, and WuXi AppTec are investing heavily in R&D and production capacity. The market is becoming increasingly consolidated, with growing technical barriers. Policy support and capital investment are also fueling market growth, with a projected CAGR of over 10% in the next five years.Despite rapid growth, the SFM market faces multiple challenges, including complex formulation development, high production costs, and difficulties in standardization. Different cell types require highly specialized environments, demanding extensive R&D and validation, while key raw materials (such as recombinant growth factors and animal-free proteins) remain costly, creating pricing pressures for early-stage adoption. Intense competition from global leaders with strong brand recognition and advanced technology creates high entry barriers for emerging players. Regulatory scrutiny on quality consistency and supply chain transparency is increasing, requiring significant investments in quality management and production technologies. Moreover, reliance on highly concentrated raw material supply chains in the US and Europe poses risks to market stability.Downstream demand for SFM is becoming more diversified and high-value-driven. With cell and gene therapies advancing into clinical and commercial phases, pharmaceutical companies and CDMOs are increasing their procurement of high-performance SFM, driving a shift from research-grade to industrial-scale production. Vaccine manufacturers and protein drug developers are adopting SFM to enhance product safety, consistency, and batch-to-batch reliability. Emerging fields such as organoids, 3D cell culture, synthetic biology, and in vitro diagnostics are expanding SFM's application scope. As regulatory frameworks and quality systems mature, purchasing strategies are moving toward globalized supply chains and long-term partnerships, providing growth opportunities for leading companies and innovation-driven differentiation for smaller players.

This report aims to provide a comprehensive presentation of the global market for Serum-Free Media, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Serum-Free Media by region & country, by Type, and by Application.

The Serum-Free Media market size, estimations, and forecasts are provided in terms of sales volume (K L) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Serum-Free Media.

Market Segmentation

By Company

• Thermo Fisher Scientific
• Merck
• Corning
• Cytiva
• Lonza
• Fujifilm
• HiMedia Laboratories
• Takara
• Kohjin Bio
• Sartorius
• Stemcell Technologies
• Jianshun Biosicences
• OPM Biosciences
• Yocon
• Sino Biological
• Basal Media
• Duoning Bio
• Bio-engine
• Bio-Rad
• Bio-Techne

Segment by Type

• Mammalian Cell Culture Media
• Stem Cell Culture Media
• Insect Cell Culture Media
• Other

Segment by Application

• Biopharmaceutical Manufacturing
• Research
• Other

By Region

• North America
  • United States
  • Canada
• Asia-Pacific
  • China
  • Japan
  • South Korea
  • Southeast Asia
  • India
  • Australia
  • Rest of Asia-Pacific
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Netherlands
  • Nordic Countries
  • Rest of Europe
• Latin America
  • Mexico
  • Brazil
  • Rest of Latin America
• Middle East & Africa
  • Turkey
  • Saudi Arabia
  • UAE
  • Rest of MEA

Chapter Outline

Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 2: Detailed analysis of Serum-Free Media manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.

Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 5: Sales, revenue of Serum-Free Media in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.

Chapter 6: Sales, revenue of Serum-Free Media in country level. It provides sigmate data by Type, and by Application for each country/region.

Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.

Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.

Chapter 9: Conclusion.

Table of Contents

1 Market Overview

• 1.1 Serum-Free Media Product Introduction
• 1.2 Global Serum-Free Media Market Size Forecast
  • 1.2.1 Global Serum-Free Media Sales Value (2020-2031)
  • 1.2.2 Global Serum-Free Media Sales Volume (2020-2031)
  • 1.2.3 Global Serum-Free Media Sales Price (2020-2031)
• 1.3 Serum-Free Media Market Trends & Drivers
  • 1.3.1 Serum-Free Media Industry Trends
  • 1.3.2 Serum-Free Media Market Drivers & Opportunity
  • 1.3.3 Serum-Free Media Market Challenges
  • 1.3.4 Serum-Free Media Market Restraints
• 1.4 Assumptions and Limitations
• 1.5 Study Objectives
• 1.6 Years Considered

2 Competitive Analysis by Company

• 2.1 Global Serum-Free Media Players Revenue Ranking (2024)
• 2.2 Global Serum-Free Media Revenue by Company (2020-2025)
• 2.3 Global Serum-Free Media Players Sales Volume Ranking (2024)
• 2.4 Global Serum-Free Media Sales Volume by Company Players (2020-2025)
• 2.5 Global Serum-Free Media Average Price by Company (2020-2025)
• 2.6 Key Manufacturers Serum-Free Media Manufacturing Base and Headquarters
• 2.7 Key Manufacturers Serum-Free Media Product Offered
• 2.8 Key Manufacturers Time to Begin Mass Production of Serum-Free Media
• 2.9 Serum-Free Media Market Competitive Analysis
  • 2.9.1 Serum-Free Media Market Concentration Rate (2020-2025)
  • 2.9.2 Global 5 and 10 Largest Manufacturers by Serum-Free Media Revenue in 2024
  • 2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Serum-Free Media as of 2024)
• 2.10 Mergers & Acquisitions, Expansion

3 Segmentation by Type

• 3.1 Introduction by Type
  • 3.1.1 Mammalian Cell Culture Media
  • 3.1.2 Stem Cell Culture Media
  • 3.1.3 Insect Cell Culture Media
  • 3.1.4 Other
• 3.2 Global Serum-Free Media Sales Value by Type
  • 3.2.1 Global Serum-Free Media Sales Value by Type (2020 VS 2024 VS 2031)
  • 3.2.2 Global Serum-Free Media Sales Value, by Type (2020-2031)
  • 3.2.3 Global Serum-Free Media Sales Value, by Type (%) (2020-2031)
• 3.3 Global Serum-Free Media Sales Volume by Type
  • 3.3.1 Global Serum-Free Media Sales Volume by Type (2020 VS 2024 VS 2031)
  • 3.3.2 Global Serum-Free Media Sales Volume, by Type (2020-2031)
  • 3.3.3 Global Serum-Free Media Sales Volume, by Type (%) (2020-2031)
• 3.4 Global Serum-Free Media Average Price by Type (2020-2031)

4 Segmentation by Application

• 4.1 Introduction by Application
  • 4.1.1 Biopharmaceutical Manufacturing
  • 4.1.2 Research
  • 4.1.3 Other
• 4.2 Global Serum-Free Media Sales Value by Application
  • 4.2.1 Global Serum-Free Media Sales Value by Application (2020 VS 2024 VS 2031)
  • 4.2.2 Global Serum-Free Media Sales Value, by Application (2020-2031)
  • 4.2.3 Global Serum-Free Media Sales Value, by Application (%) (2020-2031)
• 4.3 Global Serum-Free Media Sales Volume by Application
  • 4.3.1 Global Serum-Free Media Sales Volume by Application (2020 VS 2024 VS 2031)
  • 4.3.2 Global Serum-Free Media Sales Volume, by Application (2020-2031)
  • 4.3.3 Global Serum-Free Media Sales Volume, by Application (%) (2020-2031)
• 4.4 Global Serum-Free Media Average Price by Application (2020-2031)

5 Segmentation by Region

• 5.1 Global Serum-Free Media Sales Value by Region
  • 5.1.1 Global Serum-Free Media Sales Value by Region: 2020 VS 2024 VS 2031
  • 5.1.2 Global Serum-Free Media Sales Value by Region (2020-2025)
  • 5.1.3 Global Serum-Free Media Sales Value by Region (2026-2031)
  • 5.1.4 Global Serum-Free Media Sales Value by Region (%), (2020-2031)
• 5.2 Global Serum-Free Media Sales Volume by Region
  • 5.2.1 Global Serum-Free Media Sales Volume by Region: 2020 VS 2024 VS 2031
  • 5.2.2 Global Serum-Free Media Sales Volume by Region (2020-2025)
  • 5.2.3 Global Serum-Free Media Sales Volume by Region (2026-2031)
  • 5.2.4 Global Serum-Free Media Sales Volume by Region (%), (2020-2031)
• 5.3 Global Serum-Free Media Average Price by Region (2020-2031)
• 5.4 North America
  • 5.4.1 North America Serum-Free Media Sales Value, 2020-2031
  • 5.4.2 North America Serum-Free Media Sales Value by Country (%), 2024 VS 2031
• 5.5 Europe
  • 5.5.1 Europe Serum-Free Media Sales Value, 2020-2031
  • 5.5.2 Europe Serum-Free Media Sales Value by Country (%), 2024 VS 2031
• 5.6 Asia Pacific
  • 5.6.1 Asia Pacific Serum-Free Media Sales Value, 2020-2031
  • 5.6.2 Asia Pacific Serum-Free Media Sales Value by Region (%), 2024 VS 2031
• 5.7 South America
  • 5.7.1 South America Serum-Free Media Sales Value, 2020-2031
  • 5.7.2 South America Serum-Free Media Sales Value by Country (%), 2024 VS 2031
• 5.8 Middle East & Africa
  • 5.8.1 Middle East & Africa Serum-Free Media Sales Value, 2020-2031
  • 5.8.2 Middle East & Africa Serum-Free Media Sales Value by Country (%), 2024 VS 2031

6 Segmentation by Key Countries/Regions

• 6.1 Key Countries/Regions Serum-Free Media Sales Value Growth Trends, 2020 VS 2024 VS 2031
• 6.2 Key Countries/Regions Serum-Free Media Sales Value and Sales Volume
  • 6.2.1 Key Countries/Regions Serum-Free Media Sales Value, 2020-2031
  • 6.2.2 Key Countries/Regions Serum-Free Media Sales Volume, 2020-2031
• 6.3 United States
  • 6.3.1 United States Serum-Free Media Sales Value, 2020-2031
  • 6.3.2 United States Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.3.3 United States Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.4 Europe
  • 6.4.1 Europe Serum-Free Media Sales Value, 2020-2031
  • 6.4.2 Europe Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.4.3 Europe Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.5 China
  • 6.5.1 China Serum-Free Media Sales Value, 2020-2031
  • 6.5.2 China Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.5.3 China Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.6 Japan
  • 6.6.1 Japan Serum-Free Media Sales Value, 2020-2031
  • 6.6.2 Japan Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.6.3 Japan Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.7 South Korea
  • 6.7.1 South Korea Serum-Free Media Sales Value, 2020-2031
  • 6.7.2 South Korea Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.7.3 South Korea Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.8 Southeast Asia
  • 6.8.1 Southeast Asia Serum-Free Media Sales Value, 2020-2031
  • 6.8.2 Southeast Asia Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.8.3 Southeast Asia Serum-Free Media Sales Value by Application, 2024 VS 2031
• 6.9 India
  • 6.9.1 India Serum-Free Media Sales Value, 2020-2031
  • 6.9.2 India Serum-Free Media Sales Value by Type (%), 2024 VS 2031
  • 6.9.3 India Serum-Free Media Sales Value by Application, 2024 VS 2031

7 Company Profiles

• 7.1 Thermo Fisher Scientific
  • 7.1.1 Thermo Fisher Scientific Company Information
  • 7.1.2 Thermo Fisher Scientific Introduction and Business Overview
  • 7.1.3 Thermo Fisher Scientific Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.1.4 Thermo Fisher Scientific Serum-Free Media Product Offerings
  • 7.1.5 Thermo Fisher Scientific Recent Development
• 7.2 Merck
  • 7.2.1 Merck Company Information
  • 7.2.2 Merck Introduction and Business Overview
  • 7.2.3 Merck Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.2.4 Merck Serum-Free Media Product Offerings
  • 7.2.5 Merck Recent Development
• 7.3 Corning
  • 7.3.1 Corning Company Information
  • 7.3.2 Corning Introduction and Business Overview
  • 7.3.3 Corning Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.3.4 Corning Serum-Free Media Product Offerings
  • 7.3.5 Corning Recent Development
• 7.4 Cytiva
  • 7.4.1 Cytiva Company Information
  • 7.4.2 Cytiva Introduction and Business Overview
  • 7.4.3 Cytiva Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.4.4 Cytiva Serum-Free Media Product Offerings
  • 7.4.5 Cytiva Recent Development
• 7.5 Lonza
  • 7.5.1 Lonza Company Information
  • 7.5.2 Lonza Introduction and Business Overview
  • 7.5.3 Lonza Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.5.4 Lonza Serum-Free Media Product Offerings
  • 7.5.5 Lonza Recent Development
• 7.6 Fujifilm
  • 7.6.1 Fujifilm Company Information
  • 7.6.2 Fujifilm Introduction and Business Overview
  • 7.6.3 Fujifilm Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.6.4 Fujifilm Serum-Free Media Product Offerings
  • 7.6.5 Fujifilm Recent Development
• 7.7 HiMedia Laboratories
  • 7.7.1 HiMedia Laboratories Company Information
  • 7.7.2 HiMedia Laboratories Introduction and Business Overview
  • 7.7.3 HiMedia Laboratories Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.7.4 HiMedia Laboratories Serum-Free Media Product Offerings
  • 7.7.5 HiMedia Laboratories Recent Development
• 7.8 Takara
  • 7.8.1 Takara Company Information
  • 7.8.2 Takara Introduction and Business Overview
  • 7.8.3 Takara Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.8.4 Takara Serum-Free Media Product Offerings
  • 7.8.5 Takara Recent Development
• 7.9 Kohjin Bio
  • 7.9.1 Kohjin Bio Company Information
  • 7.9.2 Kohjin Bio Introduction and Business Overview
  • 7.9.3 Kohjin Bio Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.9.4 Kohjin Bio Serum-Free Media Product Offerings
  • 7.9.5 Kohjin Bio Recent Development
• 7.10 Sartorius
  • 7.10.1 Sartorius Company Information
  • 7.10.2 Sartorius Introduction and Business Overview
  • 7.10.3 Sartorius Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.10.4 Sartorius Serum-Free Media Product Offerings
  • 7.10.5 Sartorius Recent Development
• 7.11 Stemcell Technologies
  • 7.11.1 Stemcell Technologies Company Information
  • 7.11.2 Stemcell Technologies Introduction and Business Overview
  • 7.11.3 Stemcell Technologies Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.11.4 Stemcell Technologies Serum-Free Media Product Offerings
  • 7.11.5 Stemcell Technologies Recent Development
• 7.12 Jianshun Biosicences
  • 7.12.1 Jianshun Biosicences Company Information
  • 7.12.2 Jianshun Biosicences Introduction and Business Overview
  • 7.12.3 Jianshun Biosicences Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.12.4 Jianshun Biosicences Serum-Free Media Product Offerings
  • 7.12.5 Jianshun Biosicences Recent Development
• 7.13 OPM Biosciences
  • 7.13.1 OPM Biosciences Company Information
  • 7.13.2 OPM Biosciences Introduction and Business Overview
  • 7.13.3 OPM Biosciences Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.13.4 OPM Biosciences Serum-Free Media Product Offerings
  • 7.13.5 OPM Biosciences Recent Development
• 7.14 Yocon
  • 7.14.1 Yocon Company Information
  • 7.14.2 Yocon Introduction and Business Overview
  • 7.14.3 Yocon Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.14.4 Yocon Serum-Free Media Product Offerings
  • 7.14.5 Yocon Recent Development
• 7.15 Sino Biological
  • 7.15.1 Sino Biological Company Information
  • 7.15.2 Sino Biological Introduction and Business Overview
  • 7.15.3 Sino Biological Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.15.4 Sino Biological Serum-Free Media Product Offerings
  • 7.15.5 Sino Biological Recent Development
• 7.16 Basal Media
  • 7.16.1 Basal Media Company Information
  • 7.16.2 Basal Media Introduction and Business Overview
  • 7.16.3 Basal Media Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.16.4 Basal Media Serum-Free Media Product Offerings
  • 7.16.5 Basal Media Recent Development
• 7.17 Duoning Bio
  • 7.17.1 Duoning Bio Company Information
  • 7.17.2 Duoning Bio Introduction and Business Overview
  • 7.17.3 Duoning Bio Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.17.4 Duoning Bio Serum-Free Media Product Offerings
  • 7.17.5 Duoning Bio Recent Development
• 7.18 Bio-engine
  • 7.18.1 Bio-engine Company Information
  • 7.18.2 Bio-engine Introduction and Business Overview
  • 7.18.3 Bio-engine Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.18.4 Bio-engine Serum-Free Media Product Offerings
  • 7.18.5 Bio-engine Recent Development
• 7.19 Bio-Rad
  • 7.19.1 Bio-Rad Company Information
  • 7.19.2 Bio-Rad Introduction and Business Overview
  • 7.19.3 Bio-Rad Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.19.4 Bio-Rad Serum-Free Media Product Offerings
  • 7.19.5 Bio-Rad Recent Development
• 7.20 Bio-Techne
  • 7.20.1 Bio-Techne Company Information
  • 7.20.2 Bio-Techne Introduction and Business Overview
  • 7.20.3 Bio-Techne Serum-Free Media Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.20.4 Bio-Techne Serum-Free Media Product Offerings
  • 7.20.5 Bio-Techne Recent Development

8 Industry Chain Analysis

• 8.1 Serum-Free Media Industrial Chain
• 8.2 Serum-Free Media Upstream Analysis
  • 8.2.1 Key Raw Materials
  • 8.2.2 Raw Materials Key Suppliers
  • 8.2.3 Manufacturing Cost Structure
• 8.3 Midstream Analysis
• 8.4 Downstream Analysis (Customers Analysis)
• 8.5 Sales Model and Sales Channels
  • 8.5.1 Serum-Free Media Sales Model
  • 8.5.2 Sales Channel
  • 8.5.3 Serum-Free Media Distributors

9 Research Findings and Conclusion

10 Appendix

• 10.1 Research Methodology
  • 10.1.1 Methodology/Research Approach
    • 10.1.1.1 Research Programs/Design
    • 10.1.1.2 Market Size Estimation
    • 10.1.1.3 Market Breakdown and Data Triangulation
  • 10.1.2 Data Source
    • 10.1.2.1 Secondary Sources
    • 10.1.2.2 Primary Sources
• 10.2 Author Details
• 10.3 Disclaimer