The global market for Sickle Cell Anemia Therapeutics was estimated to be worth US$ 4067 million in 2024 and is forecast to a readjusted size of US$ 9988 million by 2031 with a CAGR of 13.7% during the forecast period 2025-2031.
Sickle cell disease (SCD) is a chronic, inherited blood disorder caused by a mutation in the beta-globin gene, leading to the production of abnormal hemoglobin called sickle hemoglobin (HbS). Under low-oxygen conditions, HbS polymerizes, causing red blood cells to assume a rigid, sickle shape. These deformed cells are prone to hemolysis and can block blood vessels, resulting in pain, anemia, and organ damage. Therapeutic approaches include pharmacological treatments (e.g., hydroxyurea, L-glutamine), gene therapy, hematopoietic stem cell transplantation, and supportive care.
Global Sickle Cell Anemia Therapeutics key players include Emmaus Medical, Theravia, Gamida Cell, GlycoMimetics, etc. Americas is the largest market, with a share about 55%, followed by Europe, and Middle East & Africa, both have a share over 35 percent. In terms of product, Blood Transfusion is the largest segment, with a share over 35%. And in terms of application, the largest application is Child, followed by Adult.The therapeutic landscape for sickle cell disease is rapidly evolving, with major pharmaceutical players (e.g., Pfizer, Novartis, Novo Nordisk) investing alongside specialized biotech firms (e.g., Bluebird Bio, CRISPR Therapeutics, Imara, Emmaus Medical). Approved treatments range from small-molecule agents like L-glutamine (Emmaus) to gene-based curative approaches such as Bluebird's Zynteglo and CRISPR/Vertex's Casgevy, marking a shift toward durable, potentially one-time interventions. Future development will prioritize expanding patient access to gene therapies, addressing long-term safety, and improving conditioning regimens for stem cell transplantation. Novel approaches, including anti-adhesion therapies (GlycoMimetics), nitric oxide modulators (Prolong), and macrophage-targeted solutions (Modus), are diversifying the pipeline. With ongoing clinical innovation and supportive regulatory momentum, the field is transitioning from symptomatic relief to functional cures, especially for underserved global populations.
This report aims to provide a comprehensive presentation of the global market for Sickle Cell Anemia Therapeutics, focusing on the total sales revenue, key companies market share and ranking, together with an analysis of Sickle Cell Anemia Therapeutics by region & country, by Type, and by Application.
The Sickle Cell Anemia Therapeutics market size, estimations, and forecasts are provided in terms of sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Sickle Cell Anemia Therapeutics.
Market Segmentation
By Company
- Emmaus Medical
- Theravia
- Pfizer
- Novartis
- Bluebird Bio
- Novo Nordisk
- Gamida Cell
- CRISPR Therapeutics
- GlycoMimetics
- Prolong Pharmaceuticals
- Modus Therapeutics
- Sangamo Biosciences
- Bioverativ
- Imara
- Ironwood Pharmaceuticals
Segment by Type
- Blood Transfusion
- Pharmacotherapy
- Bone Marrow Transplant
Segment by Application
By Region
- North America
- Asia-Pacific
- China
- Japan
- South Korea
- Southeast Asia
- India
- Australia
- Rest of Asia-Pacific
- Europe
- Germany
- France
- U.K.
- Italy
- Netherlands
- Nordic Countries
- Rest of Europe
- Latin America
- Mexico
- Brazil
- Rest of Latin America
- Middle East & Africa
- Turkey
- Saudi Arabia
- UAE
- Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size. This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Sickle Cell Anemia Therapeutics company competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Revenue of Sickle Cell Anemia Therapeutics in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Revenue of Sickle Cell Anemia Therapeutics in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product revenue, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.
Table of Contents
1 Market Overview
- 1.1 Sickle Cell Anemia Therapeutics Product Introduction
- 1.2 Global Sickle Cell Anemia Therapeutics Market Size Forecast (2020-2031)
- 1.3 Sickle Cell Anemia Therapeutics Market Trends & Drivers
- 1.3.1 Sickle Cell Anemia Therapeutics Industry Trends
- 1.3.2 Sickle Cell Anemia Therapeutics Market Drivers & Opportunity
- 1.3.3 Sickle Cell Anemia Therapeutics Market Challenges
- 1.3.4 Sickle Cell Anemia Therapeutics Market Restraints
- 1.4 Assumptions and Limitations
- 1.5 Study Objectives
- 1.6 Years Considered
2 Competitive Analysis by Company
- 2.1 Global Sickle Cell Anemia Therapeutics Players Revenue Ranking (2024)
- 2.2 Global Sickle Cell Anemia Therapeutics Revenue by Company (2020-2025)
- 2.3 Key Companies Sickle Cell Anemia Therapeutics Manufacturing Base Distribution and Headquarters
- 2.4 Key Companies Sickle Cell Anemia Therapeutics Product Offered
- 2.5 Key Companies Time to Begin Mass Production of Sickle Cell Anemia Therapeutics
- 2.6 Sickle Cell Anemia Therapeutics Market Competitive Analysis
- 2.6.1 Sickle Cell Anemia Therapeutics Market Concentration Rate (2020-2025)
- 2.6.2 Global 5 and 10 Largest Companies by Sickle Cell Anemia Therapeutics Revenue in 2024
- 2.6.3 Global Top Companies by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Sickle Cell Anemia Therapeutics as of 2024)
- 2.7 Mergers & Acquisitions, Expansion
3 Segmentation by Type
- 3.1 Introduction by Type
- 3.1.1 Blood Transfusion
- 3.1.2 Pharmacotherapy
- 3.1.3 Bone Marrow Transplant
- 3.2 Global Sickle Cell Anemia Therapeutics Sales Value by Type
- 3.2.1 Global Sickle Cell Anemia Therapeutics Sales Value by Type (2020 VS 2024 VS 2031)
- 3.2.2 Global Sickle Cell Anemia Therapeutics Sales Value, by Type (2020-2031)
- 3.2.3 Global Sickle Cell Anemia Therapeutics Sales Value, by Type (%) (2020-2031)
4 Segmentation by Application
- 4.1 Introduction by Application
- 4.2 Global Sickle Cell Anemia Therapeutics Sales Value by Application
- 4.2.1 Global Sickle Cell Anemia Therapeutics Sales Value by Application (2020 VS 2024 VS 2031)
- 4.2.2 Global Sickle Cell Anemia Therapeutics Sales Value, by Application (2020-2031)
- 4.2.3 Global Sickle Cell Anemia Therapeutics Sales Value, by Application (%) (2020-2031)
5 Segmentation by Region
- 5.1 Global Sickle Cell Anemia Therapeutics Sales Value by Region
- 5.1.1 Global Sickle Cell Anemia Therapeutics Sales Value by Region: 2020 VS 2024 VS 2031
- 5.1.2 Global Sickle Cell Anemia Therapeutics Sales Value by Region (2020-2025)
- 5.1.3 Global Sickle Cell Anemia Therapeutics Sales Value by Region (2026-2031)
- 5.1.4 Global Sickle Cell Anemia Therapeutics Sales Value by Region (%), (2020-2031)
- 5.2 North America
- 5.2.1 North America Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 5.2.2 North America Sickle Cell Anemia Therapeutics Sales Value by Country (%), 2024 VS 2031
- 5.3 Europe
- 5.3.1 Europe Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 5.3.2 Europe Sickle Cell Anemia Therapeutics Sales Value by Country (%), 2024 VS 2031
- 5.4 Asia Pacific
- 5.4.1 Asia Pacific Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 5.4.2 Asia Pacific Sickle Cell Anemia Therapeutics Sales Value by Region (%), 2024 VS 2031
- 5.5 South America
- 5.5.1 South America Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 5.5.2 South America Sickle Cell Anemia Therapeutics Sales Value by Country (%), 2024 VS 2031
- 5.6 Middle East & Africa
- 5.6.1 Middle East & Africa Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 5.6.2 Middle East & Africa Sickle Cell Anemia Therapeutics Sales Value by Country (%), 2024 VS 2031
6 Segmentation by Key Countries/Regions
- 6.1 Key Countries/Regions Sickle Cell Anemia Therapeutics Sales Value Growth Trends, 2020 VS 2024 VS 2031
- 6.2 Key Countries/Regions Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.3 United States
- 6.3.1 United States Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.3.2 United States Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.3.3 United States Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.4 Europe
- 6.4.1 Europe Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.4.2 Europe Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.4.3 Europe Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.5 China
- 6.5.1 China Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.5.2 China Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.5.3 China Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.6 Japan
- 6.6.1 Japan Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.6.2 Japan Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.6.3 Japan Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.7 South Korea
- 6.7.1 South Korea Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.7.2 South Korea Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.7.3 South Korea Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.8 Southeast Asia
- 6.8.1 Southeast Asia Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.8.2 Southeast Asia Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.8.3 Southeast Asia Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
- 6.9 India
- 6.9.1 India Sickle Cell Anemia Therapeutics Sales Value, 2020-2031
- 6.9.2 India Sickle Cell Anemia Therapeutics Sales Value by Type (%), 2024 VS 2031
- 6.9.3 India Sickle Cell Anemia Therapeutics Sales Value by Application, 2024 VS 2031
7 Company Profiles
- 7.1 Emmaus Medical
- 7.1.1 Emmaus Medical Profile
- 7.1.2 Emmaus Medical Main Business
- 7.1.3 Emmaus Medical Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.1.4 Emmaus Medical Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.1.5 Emmaus Medical Recent Developments
- 7.2 Theravia
- 7.2.1 Theravia Profile
- 7.2.2 Theravia Main Business
- 7.2.3 Theravia Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.2.4 Theravia Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.2.5 Theravia Recent Developments
- 7.3 Pfizer
- 7.3.1 Pfizer Profile
- 7.3.2 Pfizer Main Business
- 7.3.3 Pfizer Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.3.4 Pfizer Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.3.5 Pfizer Recent Developments
- 7.4 Novartis
- 7.4.1 Novartis Profile
- 7.4.2 Novartis Main Business
- 7.4.3 Novartis Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.4.4 Novartis Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.4.5 Novartis Recent Developments
- 7.5 Bluebird Bio
- 7.5.1 Bluebird Bio Profile
- 7.5.2 Bluebird Bio Main Business
- 7.5.3 Bluebird Bio Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.5.4 Bluebird Bio Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.5.5 Bluebird Bio Recent Developments
- 7.6 Novo Nordisk
- 7.6.1 Novo Nordisk Profile
- 7.6.2 Novo Nordisk Main Business
- 7.6.3 Novo Nordisk Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.6.4 Novo Nordisk Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.6.5 Novo Nordisk Recent Developments
- 7.7 Gamida Cell
- 7.7.1 Gamida Cell Profile
- 7.7.2 Gamida Cell Main Business
- 7.7.3 Gamida Cell Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.7.4 Gamida Cell Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.7.5 Gamida Cell Recent Developments
- 7.8 CRISPR Therapeutics
- 7.8.1 CRISPR Therapeutics Profile
- 7.8.2 CRISPR Therapeutics Main Business
- 7.8.3 CRISPR Therapeutics Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.8.4 CRISPR Therapeutics Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.8.5 CRISPR Therapeutics Recent Developments
- 7.9 GlycoMimetics
- 7.9.1 GlycoMimetics Profile
- 7.9.2 GlycoMimetics Main Business
- 7.9.3 GlycoMimetics Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.9.4 GlycoMimetics Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.9.5 GlycoMimetics Recent Developments
- 7.10 Prolong Pharmaceuticals
- 7.10.1 Prolong Pharmaceuticals Profile
- 7.10.2 Prolong Pharmaceuticals Main Business
- 7.10.3 Prolong Pharmaceuticals Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.10.4 Prolong Pharmaceuticals Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.10.5 Prolong Pharmaceuticals Recent Developments
- 7.11 Modus Therapeutics
- 7.11.1 Modus Therapeutics Profile
- 7.11.2 Modus Therapeutics Main Business
- 7.11.3 Modus Therapeutics Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.11.4 Modus Therapeutics Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.11.5 Modus Therapeutics Recent Developments
- 7.12 Sangamo Biosciences
- 7.12.1 Sangamo Biosciences Profile
- 7.12.2 Sangamo Biosciences Main Business
- 7.12.3 Sangamo Biosciences Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.12.4 Sangamo Biosciences Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.12.5 Sangamo Biosciences Recent Developments
- 7.13 Bioverativ
- 7.13.1 Bioverativ Profile
- 7.13.2 Bioverativ Main Business
- 7.13.3 Bioverativ Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.13.4 Bioverativ Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.13.5 Bioverativ Recent Developments
- 7.14 Imara
- 7.14.1 Imara Profile
- 7.14.2 Imara Main Business
- 7.14.3 Imara Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.14.4 Imara Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.14.5 Imara Recent Developments
- 7.15 Ironwood Pharmaceuticals
- 7.15.1 Ironwood Pharmaceuticals Profile
- 7.15.2 Ironwood Pharmaceuticals Main Business
- 7.15.3 Ironwood Pharmaceuticals Sickle Cell Anemia Therapeutics Products, Services and Solutions
- 7.15.4 Ironwood Pharmaceuticals Sickle Cell Anemia Therapeutics Revenue (US$ Million) & (2020-2025)
- 7.15.5 Ironwood Pharmaceuticals Recent Developments
8 Industry Chain Analysis
- 8.1 Sickle Cell Anemia Therapeutics Industrial Chain
- 8.2 Sickle Cell Anemia Therapeutics Upstream Analysis
- 8.2.1 Key Raw Materials
- 8.2.2 Raw Materials Key Suppliers
- 8.2.3 Manufacturing Cost Structure
- 8.3 Midstream Analysis
- 8.4 Downstream Analysis (Customers Analysis)
- 8.5 Sales Model and Sales Channels
- 8.5.1 Sickle Cell Anemia Therapeutics Sales Model
- 8.5.2 Sales Channel
- 8.5.3 Sickle Cell Anemia Therapeutics Distributors
9 Research Findings and Conclusion
10 Appendix
- 10.1 Research Methodology
- 10.1.1 Methodology/Research Approach
- 10.1.1.1 Research Programs/Design
- 10.1.1.2 Market Size Estimation
- 10.1.1.3 Market Breakdown and Data Triangulation
- 10.1.2 Data Source
- 10.1.2.1 Secondary Sources
- 10.1.2.2 Primary Sources
- 10.2 Author Details
- 10.3 Disclaimer