세계의 Z-L-Valine NCA - 시장 점유율과 순위, 전체 판매량 및 수요 예측(2025-2031년)

The global market for Z-L-Valine NCA was estimated to be worth US$ 50.81 million in 2024 and is forecast to a readjusted size of US$ 69.77 million by 2031 with a CAGR of 4.8% during the forecast period 2025-2031.

This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on Z-L-Valine NCA cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply chain reconfigurations.

In 2024, global Z-L-Valine NCA production reached approximately 19 MT, with an average global market price of around US$ 2676 per kg.

Z-L-Valine NCA is a protected amino acid derivative widely used as a monomer for controlled ring-opening polymerization (ROP) in polypeptide synthesis. Structurally, it is the N-carboxyanhydride of N-benzyloxycarbonyl (Z)-protected L-valine. The "Z" group serves as a temporary protecting group for the amino functionality, allowing selective polymerization at the carboxyanhydride site. This compound is highly reactive toward nucleophiles such as amines, making it a preferred intermediate for preparing well-defined polypeptides, block copolymers, and functional biomaterials.

Due to its reactivity and susceptibility to hydrolysis, Z-L-Valine NCA requires strict moisture-free handling, inert gas packaging, and cold storage. It is typically sold as a white to off-white crystalline powder in sealed containers ranging from gram-scale laboratory vials to multi-kilogram industrial lots. Its CAS number, purity specification, and COA (Certificate of Analysis) are essential quality benchmarks for buyers, particularly in regulated sectors such as pharmaceuticals.

The market can be defined as a niche segment within the broader peptide-synthesis and specialty monomer industry, serving research organizations, custom synthesis companies, polymer/material science developers, and pharmaceutical manufacturers.

The Z-L-Valine NCA market is expected to grow alongside several converging scientific and industrial trends:

Expansion of Peptide-Based Therapeutics - As biologics and peptide drugs gain traction, there is increasing interest in novel delivery carriers and conjugates that extend half-life or enhance targeting. Polypeptides from NCAs are attractive due to their biodegradability and structural precision.

Growth in Biomedical Materials - Hydrogels, coatings, and scaffolds based on synthetic polypeptides are being explored for wound healing, implant coatings, and regenerative medicine. This pushes demand for monomers like Z-L-Valine NCA in both academic and commercial R&D.

Advances in Controlled Polymerization Techniques - Improved initiator systems and polymerization conditions are enabling better molecular weight control and block-copolymer architectures, which in turn require high-purity NCAs with minimal side products.

This report aims to provide a comprehensive presentation of the global market for Z-L-Valine NCA, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Z-L-Valine NCA by region & country, by Type, and by Application.

The Z-L-Valine NCA market size, estimations, and forecasts are provided in terms of sales volume (kg) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Z-L-Valine NCA.

Market Segmentation

By Company

• ISOCHEM
• KPX Life Science
• Caming Pharmaceutical
• Alfa Chemistry
• Actylis
• ClearSynth
• P&S Chemicals
• BLDpharm
• J & K SCIENTIFIC
• AK Scientific
• Chemos GmbH
• Aecochem
• Jinan APTC

Segment by Type

• Purity 98%
• Purity 95%
• Others

Segment by Application

• Research Institutions
• Pharmaceutical Synthesis

By Region

• North America
  • United States
  • Canada
• Asia-Pacific
  • China
  • Japan
  • South Korea
  • Southeast Asia
  • India
  • Australia
  • Rest of Asia-Pacific
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Netherlands
  • Nordic Countries
  • Rest of Europe
• Latin America
  • Mexico
  • Brazil
  • Rest of Latin America
• Middle East & Africa
  • Turkey
  • Saudi Arabia
  • UAE
  • Rest of MEA

Chapter Outline

Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 2: Detailed analysis of Z-L-Valine NCA manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.

Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 5: Sales, revenue of Z-L-Valine NCA in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.

Chapter 6: Sales, revenue of Z-L-Valine NCA in country level. It provides sigmate data by Type, and by Application for each country/region.

Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.

Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.

Chapter 9: Conclusion.

Table of Contents

1 Market Overview

• 1.1 Z-L-Valine NCA Product Introduction
• 1.2 Global Z-L-Valine NCA Market Size Forecast
  • 1.2.1 Global Z-L-Valine NCA Sales Value (2020-2031)
  • 1.2.2 Global Z-L-Valine NCA Sales Volume (2020-2031)
  • 1.2.3 Global Z-L-Valine NCA Sales Price (2020-2031)
• 1.3 Z-L-Valine NCA Market Trends & Drivers
  • 1.3.1 Z-L-Valine NCA Industry Trends
  • 1.3.2 Z-L-Valine NCA Market Drivers & Opportunity
  • 1.3.3 Z-L-Valine NCA Market Challenges
  • 1.3.4 Z-L-Valine NCA Market Restraints
• 1.4 Assumptions and Limitations
• 1.5 Study Objectives
• 1.6 Years Considered

2 Competitive Analysis by Company

• 2.1 Global Z-L-Valine NCA Players Revenue Ranking (2024)
• 2.2 Global Z-L-Valine NCA Revenue by Company (2020-2025)
• 2.3 Global Z-L-Valine NCA Players Sales Volume Ranking (2024)
• 2.4 Global Z-L-Valine NCA Sales Volume by Company Players (2020-2025)
• 2.5 Global Z-L-Valine NCA Average Price by Company (2020-2025)
• 2.6 Key Manufacturers Z-L-Valine NCA Manufacturing Base and Headquarters
• 2.7 Key Manufacturers Z-L-Valine NCA Product Offered
• 2.8 Key Manufacturers Time to Begin Mass Production of Z-L-Valine NCA
• 2.9 Z-L-Valine NCA Market Competitive Analysis
  • 2.9.1 Z-L-Valine NCA Market Concentration Rate (2020-2025)
  • 2.9.2 Global 5 and 10 Largest Manufacturers by Z-L-Valine NCA Revenue in 2024
  • 2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Z-L-Valine NCA as of 2024)
• 2.10 Mergers & Acquisitions, Expansion

3 Segmentation by Type

• 3.1 Introduction by Type
  • 3.1.1 Purity 98%
  • 3.1.2 Purity 95%
  • 3.1.3 Others
• 3.2 Global Z-L-Valine NCA Sales Value by Type
  • 3.2.1 Global Z-L-Valine NCA Sales Value by Type (2020 VS 2024 VS 2031)
  • 3.2.2 Global Z-L-Valine NCA Sales Value, by Type (2020-2031)
  • 3.2.3 Global Z-L-Valine NCA Sales Value, by Type (%) (2020-2031)
• 3.3 Global Z-L-Valine NCA Sales Volume by Type
  • 3.3.1 Global Z-L-Valine NCA Sales Volume by Type (2020 VS 2024 VS 2031)
  • 3.3.2 Global Z-L-Valine NCA Sales Volume, by Type (2020-2031)
  • 3.3.3 Global Z-L-Valine NCA Sales Volume, by Type (%) (2020-2031)
• 3.4 Global Z-L-Valine NCA Average Price by Type (2020-2031)

4 Segmentation by Application

• 4.1 Introduction by Application
  • 4.1.1 Research Institutions
  • 4.1.2 Pharmaceutical Synthesis
• 4.2 Global Z-L-Valine NCA Sales Value by Application
  • 4.2.1 Global Z-L-Valine NCA Sales Value by Application (2020 VS 2024 VS 2031)
  • 4.2.2 Global Z-L-Valine NCA Sales Value, by Application (2020-2031)
  • 4.2.3 Global Z-L-Valine NCA Sales Value, by Application (%) (2020-2031)
• 4.3 Global Z-L-Valine NCA Sales Volume by Application
  • 4.3.1 Global Z-L-Valine NCA Sales Volume by Application (2020 VS 2024 VS 2031)
  • 4.3.2 Global Z-L-Valine NCA Sales Volume, by Application (2020-2031)
  • 4.3.3 Global Z-L-Valine NCA Sales Volume, by Application (%) (2020-2031)
• 4.4 Global Z-L-Valine NCA Average Price by Application (2020-2031)

5 Segmentation by Region

• 5.1 Global Z-L-Valine NCA Sales Value by Region
  • 5.1.1 Global Z-L-Valine NCA Sales Value by Region: 2020 VS 2024 VS 2031
  • 5.1.2 Global Z-L-Valine NCA Sales Value by Region (2020-2025)
  • 5.1.3 Global Z-L-Valine NCA Sales Value by Region (2026-2031)
  • 5.1.4 Global Z-L-Valine NCA Sales Value by Region (%), (2020-2031)
• 5.2 Global Z-L-Valine NCA Sales Volume by Region
  • 5.2.1 Global Z-L-Valine NCA Sales Volume by Region: 2020 VS 2024 VS 2031
  • 5.2.2 Global Z-L-Valine NCA Sales Volume by Region (2020-2025)
  • 5.2.3 Global Z-L-Valine NCA Sales Volume by Region (2026-2031)
  • 5.2.4 Global Z-L-Valine NCA Sales Volume by Region (%), (2020-2031)
• 5.3 Global Z-L-Valine NCA Average Price by Region (2020-2031)
• 5.4 North America
  • 5.4.1 North America Z-L-Valine NCA Sales Value, 2020-2031
  • 5.4.2 North America Z-L-Valine NCA Sales Value by Country (%), 2024 VS 2031
• 5.5 Europe
  • 5.5.1 Europe Z-L-Valine NCA Sales Value, 2020-2031
  • 5.5.2 Europe Z-L-Valine NCA Sales Value by Country (%), 2024 VS 2031
• 5.6 Asia Pacific
  • 5.6.1 Asia Pacific Z-L-Valine NCA Sales Value, 2020-2031
  • 5.6.2 Asia Pacific Z-L-Valine NCA Sales Value by Region (%), 2024 VS 2031
• 5.7 South America
  • 5.7.1 South America Z-L-Valine NCA Sales Value, 2020-2031
  • 5.7.2 South America Z-L-Valine NCA Sales Value by Country (%), 2024 VS 2031
• 5.8 Middle East & Africa
  • 5.8.1 Middle East & Africa Z-L-Valine NCA Sales Value, 2020-2031
  • 5.8.2 Middle East & Africa Z-L-Valine NCA Sales Value by Country (%), 2024 VS 2031

6 Segmentation by Key Countries/Regions

• 6.1 Key Countries/Regions Z-L-Valine NCA Sales Value Growth Trends, 2020 VS 2024 VS 2031
• 6.2 Key Countries/Regions Z-L-Valine NCA Sales Value and Sales Volume
  • 6.2.1 Key Countries/Regions Z-L-Valine NCA Sales Value, 2020-2031
  • 6.2.2 Key Countries/Regions Z-L-Valine NCA Sales Volume, 2020-2031
• 6.3 United States
  • 6.3.1 United States Z-L-Valine NCA Sales Value, 2020-2031
  • 6.3.2 United States Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.3.3 United States Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.4 Europe
  • 6.4.1 Europe Z-L-Valine NCA Sales Value, 2020-2031
  • 6.4.2 Europe Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.4.3 Europe Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.5 China
  • 6.5.1 China Z-L-Valine NCA Sales Value, 2020-2031
  • 6.5.2 China Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.5.3 China Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.6 Japan
  • 6.6.1 Japan Z-L-Valine NCA Sales Value, 2020-2031
  • 6.6.2 Japan Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.6.3 Japan Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.7 South Korea
  • 6.7.1 South Korea Z-L-Valine NCA Sales Value, 2020-2031
  • 6.7.2 South Korea Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.7.3 South Korea Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.8 Southeast Asia
  • 6.8.1 Southeast Asia Z-L-Valine NCA Sales Value, 2020-2031
  • 6.8.2 Southeast Asia Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.8.3 Southeast Asia Z-L-Valine NCA Sales Value by Application, 2024 VS 2031
• 6.9 India
  • 6.9.1 India Z-L-Valine NCA Sales Value, 2020-2031
  • 6.9.2 India Z-L-Valine NCA Sales Value by Type (%), 2024 VS 2031
  • 6.9.3 India Z-L-Valine NCA Sales Value by Application, 2024 VS 2031

7 Company Profiles

• 7.1 ISOCHEM
  • 7.1.1 ISOCHEM Company Information
  • 7.1.2 ISOCHEM Introduction and Business Overview
  • 7.1.3 ISOCHEM Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.1.4 ISOCHEM Z-L-Valine NCA Product Offerings
  • 7.1.5 ISOCHEM Recent Development
• 7.2 KPX Life Science
  • 7.2.1 KPX Life Science Company Information
  • 7.2.2 KPX Life Science Introduction and Business Overview
  • 7.2.3 KPX Life Science Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.2.4 KPX Life Science Z-L-Valine NCA Product Offerings
  • 7.2.5 KPX Life Science Recent Development
• 7.3 Caming Pharmaceutical
  • 7.3.1 Caming Pharmaceutical Company Information
  • 7.3.2 Caming Pharmaceutical Introduction and Business Overview
  • 7.3.3 Caming Pharmaceutical Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.3.4 Caming Pharmaceutical Z-L-Valine NCA Product Offerings
  • 7.3.5 Caming Pharmaceutical Recent Development
• 7.4 Alfa Chemistry
  • 7.4.1 Alfa Chemistry Company Information
  • 7.4.2 Alfa Chemistry Introduction and Business Overview
  • 7.4.3 Alfa Chemistry Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.4.4 Alfa Chemistry Z-L-Valine NCA Product Offerings
  • 7.4.5 Alfa Chemistry Recent Development
• 7.5 Actylis
  • 7.5.1 Actylis Company Information
  • 7.5.2 Actylis Introduction and Business Overview
  • 7.5.3 Actylis Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.5.4 Actylis Z-L-Valine NCA Product Offerings
  • 7.5.5 Actylis Recent Development
• 7.6 ClearSynth
  • 7.6.1 ClearSynth Company Information
  • 7.6.2 ClearSynth Introduction and Business Overview
  • 7.6.3 ClearSynth Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.6.4 ClearSynth Z-L-Valine NCA Product Offerings
  • 7.6.5 ClearSynth Recent Development
• 7.7 P&S Chemicals
  • 7.7.1 P&S Chemicals Company Information
  • 7.7.2 P&S Chemicals Introduction and Business Overview
  • 7.7.3 P&S Chemicals Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.7.4 P&S Chemicals Z-L-Valine NCA Product Offerings
  • 7.7.5 P&S Chemicals Recent Development
• 7.8 BLDpharm
  • 7.8.1 BLDpharm Company Information
  • 7.8.2 BLDpharm Introduction and Business Overview
  • 7.8.3 BLDpharm Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.8.4 BLDpharm Z-L-Valine NCA Product Offerings
  • 7.8.5 BLDpharm Recent Development
• 7.9 J & K SCIENTIFIC
  • 7.9.1 J & K SCIENTIFIC Company Information
  • 7.9.2 J & K SCIENTIFIC Introduction and Business Overview
  • 7.9.3 J & K SCIENTIFIC Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.9.4 J & K SCIENTIFIC Z-L-Valine NCA Product Offerings
  • 7.9.5 J & K SCIENTIFIC Recent Development
• 7.10 AK Scientific
  • 7.10.1 AK Scientific Company Information
  • 7.10.2 AK Scientific Introduction and Business Overview
  • 7.10.3 AK Scientific Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.10.4 AK Scientific Z-L-Valine NCA Product Offerings
  • 7.10.5 AK Scientific Recent Development
• 7.11 Chemos GmbH
  • 7.11.1 Chemos GmbH Company Information
  • 7.11.2 Chemos GmbH Introduction and Business Overview
  • 7.11.3 Chemos GmbH Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.11.4 Chemos GmbH Z-L-Valine NCA Product Offerings
  • 7.11.5 Chemos GmbH Recent Development
• 7.12 Aecochem
  • 7.12.1 Aecochem Company Information
  • 7.12.2 Aecochem Introduction and Business Overview
  • 7.12.3 Aecochem Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.12.4 Aecochem Z-L-Valine NCA Product Offerings
  • 7.12.5 Aecochem Recent Development
• 7.13 Jinan APTC
  • 7.13.1 Jinan APTC Company Information
  • 7.13.2 Jinan APTC Introduction and Business Overview
  • 7.13.3 Jinan APTC Z-L-Valine NCA Sales, Revenue, Price and Gross Margin (2020-2025)
  • 7.13.4 Jinan APTC Z-L-Valine NCA Product Offerings
  • 7.13.5 Jinan APTC Recent Development

8 Industry Chain Analysis

• 8.1 Z-L-Valine NCA Industrial Chain
• 8.2 Z-L-Valine NCA Upstream Analysis
  • 8.2.1 Key Raw Materials
  • 8.2.2 Raw Materials Key Suppliers
  • 8.2.3 Manufacturing Cost Structure
• 8.3 Midstream Analysis
• 8.4 Downstream Analysis (Customers Analysis)
• 8.5 Sales Model and Sales Channels
  • 8.5.1 Z-L-Valine NCA Sales Model
  • 8.5.2 Sales Channel
  • 8.5.3 Z-L-Valine NCA Distributors

9 Research Findings and Conclusion

10 Appendix

• 10.1 Research Methodology
  • 10.1.1 Methodology/Research Approach
    • 10.1.1.1 Research Programs/Design
    • 10.1.1.2 Market Size Estimation
    • 10.1.1.3 Market Breakdown and Data Triangulation
  • 10.1.2 Data Source
    • 10.1.2.1 Secondary Sources
    • 10.1.2.2 Primary Sources
• 10.2 Author Details
• 10.3 Disclaimer