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NGS Library Preparation Market Size, Share, Growth Analysis, By Product, By Sequencing Type, By Application, By End User, By Region - Industry Forecast 2025-2032

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  • Illumina(United States)
  • Bio-Rad Laboratories(United States)
  • Thermo Fisher Scientific(United States)
  • PerkinElmer(United States)
  • F. Hoffmann-La Roche(Switzerland)
  • New England Biolabs(United States)
  • Tecan Group(Switzerland)
  • Merck KGaA(Germany)
  • BGI Group(China)
  • Pacific Biosciences(PacBio)(United States)
  • Oxford Nanopore Technologies(United Kingdom)
  • 10x Genomics(United States)
  • Molecular Loop(United States)
  • Alida Biosciences(United States)
  • seqWell(United States)
  • Claret Bioscience(United States)
  • MagBio Genomics(United States)

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KSA 25.02.17

Global NGS Library Preparation Market size was valued at USD 3.6 billion in 2023 and is poised to grow from USD 4.13 billion in 2024 to USD 12.47 billion by 2032, growing at a CAGR of 14.8% during the forecast period (2025-2032).

The next-generation sequencing (NGS) workflow encompasses critical steps such as library preparation, sequencing, bioinformatics, and sample pre-processing, with library preparation being a pivotal component. This involves ensuring DNA or RNA samples are sequencer-compatible through essential procedures like adapter ligation, library quantitation, and nucleic acid fragmentation. Numerous vendors now offer diverse solutions aimed at optimizing NGS library preparation. The process mandates isolating, fragmenting, and end-repairing nucleic acids, followed by ligation with adapters. Proper preparation is vital, as the library's complexity mirrors that of the sample, impacting overall NGS results significantly. Mitigating PCR or amplification-induced biases while maximizing complexity is crucial for achieving high-quality outcomes, demonstrating the importance of investing in quality instruments, kits, and reagents available in the market.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global Ngs Library Preparation market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global Ngs Library Preparation Market Segmental Analysis

Global NGS Library Preparation Market is segmented by Product, Sequencing Type, Application, End User and region. Based on Product, the market is segmented into Reagents & Consumables, DNA Library Preparation Kits, Library Preparation Kits, RNA Library Preparation Kits, Other Reagents & Consumables and Instruments. Based on Sequencing Type, the market is segmented into Targeted Genome Sequencing, Whole Genome Sequencing, Whole Exome Sequencing and Other Sequencing Types. Based on Application, the market is segmented into Drug & Biomarker Discovery, Disease Diagnostics, Cancer Diagnostics, Reproductive Health Diagnostics, Infectious Disease Diagnostics, Other Disease Diagnostic Applications and Others. Based on End User, the market is segmented into Hospitals and Clinics, Academic and Research Institutions, Pharmaceutical and Biotechnology Companies and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Global Ngs Library Preparation Market

The global NGS library preparation market is being driven by multiple factors, including significant investments aimed at advancing diagnostic techniques. Notably, the declining costs associated with sequencing technologies, coupled with a rise in the prevalence of genetic disorders, are propelling the adoption of NGS in various diagnostic applications. Furthermore, increased expenditure on research and development within the healthcare sector enhances market growth prospects. The expanding array of applications for next-generation sequencing and the proliferation of collaborative efforts among companies to innovate and refine library preparation protocols are also expected to provide substantial momentum to the market in the foreseeable future.

Restraints in the Global Ngs Library Preparation Market

The growth of the global NGS library preparation market is likely to be hindered by various financial challenges, particularly in developing nations where budget constraints are prevalent. This financial limitation poses a significant barrier to market expansion. Furthermore, regulatory and standardization concerns related to diagnostic testing present additional challenges. Smaller and mid-sized laboratories may struggle due to their limited expertise and sequencing capabilities, further impeding the overall development of the market. Together, these factors create a complex landscape that inhibits the progress and widespread adoption of NGS library preparation technologies across different regions.

Market Trends of the Global Ngs Library Preparation Market

The Global NGS Library Preparation market is witnessing a significant shift towards automation and robotics, driven by the increasing demand for efficiency and accuracy in sequencing processes. As researchers seek to streamline workflows and reduce labor costs, automated library preparation solutions are rapidly gaining traction, allowing for higher throughput and minimized hands-on intervention. This trend not only enhances productivity but also significantly reduces human error, leading to more reliable results. Consequently, the market is expected to experience substantial growth as institutions prioritize these advanced technologies to keep pace with the expanding genomic research landscape and the need for rapid, scalable solutions.

Table of Contents

Introduction

  • Objectives of the Study
  • Scope of the Report
  • Definitions

Research Methodology

  • Information Procurement
  • Secondary & Primary Data Methods
  • Market Size Estimation
  • Market Assumptions & Limitations

Executive Summary

  • Global Market Outlook
  • Supply & Demand Trend Analysis
  • Segmental Opportunity Analysis

Market Dynamics & Outlook

  • Market Overview
  • Market Size
  • Market Dynamics
    • Drivers & Opportunities
    • Restraints & Challenges
  • Porters Analysis
    • Competitive rivalry
    • Threat of substitute
    • Bargaining power of buyers
    • Threat of new entrants
    • Bargaining power of suppliers

Key Market Insights

  • Key Success Factors
  • Degree of Competition
  • Top Investment Pockets
  • Market Ecosystem
  • Market Attractiveness Index, 2024
  • PESTEL Analysis
  • Macro-Economic Indicators
  • Value Chain Analysis
  • Pricing Analysis
  • Regulatory Landscape
  • Case Studies

Global NGS Library Preparation Market Size by Product & CAGR (2025-2032)

  • Market Overview
  • Reagents & Consumables
  • DNA Library Preparation Kits
  • Library Preparation Kits
  • RNA Library Preparation Kits
  • Other Reagents & Consumables
  • Instruments

Global NGS Library Preparation Market Size by Sequencing Type & CAGR (2025-2032)

  • Market Overview
  • Targeted Genome Sequencing
  • Whole Genome Sequencing
  • Whole Exome Sequencing
  • Other Sequencing Types

Global NGS Library Preparation Market Size by Application & CAGR (2025-2032)

  • Market Overview
  • Drug & Biomarker Discovery
  • Disease Diagnostics
  • Cancer Diagnostics
  • Reproductive Health Diagnostics
  • Infectious Disease Diagnostics
  • Other Disease Diagnostic Applications
  • Others

Global NGS Library Preparation Market Size by End User & CAGR (2025-2032)

  • Market Overview
  • Hospitals and Clinics
  • Academic and Research Institutions
  • Pharmaceutical and Biotechnology Companies
  • Others

Global NGS Library Preparation Market Size & CAGR (2025-2032)

  • North America (Product, Sequencing Type, Application, End User)
    • US
    • Canada
  • Europe (Product, Sequencing Type, Application, End User)
    • Germany
    • Spain
    • France
    • UK
    • Italy
    • Rest of Europe
  • Asia Pacific (Product, Sequencing Type, Application, End User)
    • China
    • India
    • Japan
    • South Korea
    • Rest of Asia-Pacific
  • Latin America (Product, Sequencing Type, Application, End User)
    • Brazil
    • Rest of Latin America
  • Middle East & Africa (Product, Sequencing Type, Application, End User)
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

Competitive Intelligence

  • Top 5 Player Comparison
  • Market Positioning of Key Players, 2024
  • Strategies Adopted by Key Market Players
  • Recent Developments in the Market
  • Company Market Share Analysis, 2024
  • Company Profiles of All Key Players
    • Company Details
    • Product Portfolio Analysis
    • Company's Segmental Share Analysis
    • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

  • Illumina (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Bio-Rad Laboratories (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Thermo Fisher Scientific (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • PerkinElmer (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • F. Hoffmann-La Roche (Switzerland)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • New England Biolabs (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Tecan Group (Switzerland)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Merck KGaA (Germany)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • BGI Group (China)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Pacific Biosciences (PacBio) (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Oxford Nanopore Technologies (United Kingdom)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • 10x Genomics (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Molecular Loop (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Alida Biosciences (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • seqWell (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • Claret Bioscience (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments
  • MagBio Genomics (United States)
    • Company Overview
    • Business Segment Overview
    • Financial Updates
    • Key Developments

Conclusion & Recommendations

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