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시장보고서
상품코드
2078365
분자 접착제 시장 규모, 점유율 및 성장 분석 : 대상 클래스별, 적응증별, 개발 단계별, 최종사용자별, 유통경로별, 지역별 - 업계 예측(2026-2033년)Molecular Glues Market Size, Share, and Growth Analysis, By Target Class, By Indication, By Stage, By End-User, By Distribution, By Region - Industry Forecast 2026-2033 |
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세계의 분자 접착제 시장 규모는 2024년에 6억 5,000만 달러로 평가되었고, 2025년 7억 9,000만 달러에서 2033년까지 38억 5,000만 달러로 성장하여 예측 기간(2026-2033년)에 CAGR 21.8%를 기록할 전망입니다.
세계 분자 접착제 시장은 세포 내 유비퀴틴 리가제의 작용을 재유도함으로써, 질병의 원인이 되는 단백질의 표적 분해를 가능하게 하는 저분자 접착제의 혁신적인 잠재력에 힘입어 성장하고 있습니다. 이러한 콤팩트한 설계는 생물학적 제제를 대체할 유망한 대안이 되며, 경구 투여를 가능하게 할 뿐만 아니라, KRAS(G12C)나 IKZF1/3 등 기존에는 약물 표적화가 어렵다고 여겨졌던 단백질에 대한 표적화를 용이하게 하고 있습니다. 최근 구조 설계 기술의 발전으로 인해, 분자 접착제 제제의 적용 범위는 특히 종양학 및 신경퇴행성 질환 분야에서 확대되고 있습니다. 규제 당국의 강력한 지원과 보험사의 이러한 치료제에 대한 급여 의지 고조뿐만 아니라, 레날리도마이드 등 기존 약물을 통해 사망률이 감소한 사실이 입증됨에 따라 초기 단계 개발에 대한 투자가 점점 더 매력적으로 여겨지고 있으며, 치료가 어려운 질환에 대한 새로운 치료 옵션을 발굴하기 위한 고처리량 스크리닝 플랫폼 구축이 촉진되고 있습니다.
세계 분자 접착제 시장의 성장 요인
세계 분자 접착제 시장은 그동안 '신약 개발 불가능'으로 간주되던 질환 관련 단백질을 선택적으로 분해할 수 있는 분자 접착제의 치료 가능성 확대에 힘입어 주도되고 있습니다. 이러한 혁신은 약리학 분야에서 새로운 유형의 치료제를 탄생시켰으며, 획기적인 신약 개발 이니셔티브의 길을 열어주고 있습니다. 각 제약사는 경쟁사와의 차별화를 꾀하기 위해 이러한 혁신적인 접근 방식을 채택하고 있는 반면, 투자자들은 분자 접착제 기술을 기존 파이프라인에 통합하기 위한 자금 지원에 적극적인 태도를 보이고 있습니다. 이러한 시너지 효과로 인해 기업 시장 진출이 가속화되고, 학계와 생명공학 업계 간의 협력이 강화되고 있습니다. 이를 통해 접착제 분야의 기술 발전이 촉진되고 있으며, 규제 당국과 의료 종사자들 간의 신뢰도 높아지고 있습니다.
세계 분자 접착제 시장의 제약 요인
현재 전 세계 분자 접착제 시장은 주로 이러한 물질들이 가져오는 새로운 작용기전에 기인하여 몇 가지 제약에 직면해 있습니다. 규제 당국은 평가 절차를 조정해야 하는 상황에 놓여 있으며, 그 결과 심사 기간이 길어지거나 제출해야 할 데이터 양이 늘어날 가능성이 있습니다. 이로 인해 안전성 및 오프타겟 위험과 관련하여 제조업체와 규제 당국의 심사 담당자 간에 여러 차례 협의가 이루어지는 경우가 많아, 개발 기간이 더욱 길어지고 비용이 증가하게 됩니다. 그 결과, 잠재적 투자자들은 분자 접착 기술을 활용하는 기업에 대한 지원에 소극적인 태도를 보일 가능성이 있습니다. 게다가 제조업체들은 이러한 제품의 분류와 관련하여 모호함에 직면하고 있으며, 그 결과 표시 사항이나 시판 후 조건이 불투명해져, 결국 상업화 노력을 저해하고 시장 접근을 제한하게 됩니다.
세계 분자 접착제 시장 동향
세계 분자 접착제 시장은 의약품 개발 분야에서 정밀 단백질 분해제의 채택이 확대됨에 따라 눈부신 성장을 이루고 있습니다. 이러한 분자 접착제는 기존에는 약물화가 어렵다고 여겨졌던 단백질을 표적으로 삼아 제거할 수 있게 함으로써, 신약 개발 과정을 효율화하고, 보다 신속하며 비용 대비 효과가 높은 개발 과정을 실현합니다. 각 제약사가 정밀 의학을 점점 더 중시하는 가운데, 바이오기술 분야의 혁신 기업과 대형 제약사 간에 제휴 관계가 형성되며 다양한 의약품 개발 파이프라인이 육성되고 있습니다. 이러한 시너지 효과로 인해 신약의 임상시험 진입이 가속화되고, 복잡한 질병 경로에 초점을 맞춘 전 세계적인 치료 환경이 개선되며, 궁극적으로는 전 세계 환자들의 치료 성과가 향상될 것으로 기대됩니다.
자주 묻는 질문
목차
서론
조사 방법
주요 요약
시장 역학과 전망
주요 시장 인사이트
세계의 분자 접착제 시장 규모 : 타겟 클래스별
세계의 분자 접착제 시장 규모 : 적응증별
세계의 분자 접착제 시장 규모 : 스테이지별
세계의 분자 접착제 시장 규모 : 최종사용자별
세계의 분자 접착제 시장 규모 : 유통별
세계의 분자 접착제 시장 규모 : 지역별
경쟁 정보
주요 기업 개요
결론과 제안
LSH 26.07.08Global Molecular Glues Market size was valued at USD 650 Million in 2024 and is poised to grow from USD 790 Million in 2025 to USD 3850 Million by 2033, growing at a CAGR of 21.8% during the forecast period (2026-2033).
The global molecular glues market is driven by the innovative potential of small molecular glues that enable targeted degradation of disease-causing proteins through the redirection of cellular ubiquitin-ligases. Their compact design offers a promising alternative to biologic drugs, allowing oral administration and facilitating the targeting of previously undruggable proteins such as KRAS(G12C) and IKZF1/3. Advances in structural design technologies over recent years have broadened the application of molecular glue drugs, particularly in oncology and neurodegeneration. Strong regulatory support and willingness from payers to reimburse these therapeutics, alongside evidenced reductions in mortality rates from existing drugs like lenalidomide, have made investment in early-stage development increasingly attractive, fostering the creation of high-throughput screening platforms to discover new therapeutic options for challenging diseases.
Top-down and bottom-up approaches were used to estimate and validate the size of the Global Molecular Glues market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.
Global Molecular Glues Market Segments Analysis
Global molecular glues market is segmented by target class, indication, stage, end-user, distribution and region. Based on target class, the market is segmented into E3 Ligase-based molecular glues, kinase molecular glues and transcription factor glues. Based on indication, the market is segmented into oncology, neurological disorders and autoimmune. Based on stage, the market is segmented into approved, clinical and preclinical. Based on end-user, the market is segmented into pharma & biotech companies and research institutes. Based on distribution, the market is segmented into hospital pharmacies and specialty pharmacies. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.
Driver of the Global Molecular Glues Market
The Global Molecular Glues market is propelled by the expanding therapeutic potential of molecular glues, which are capable of selectively degrading disease-related proteins previously deemed "undruggable." This innovation has ushered in a new class of therapeutics in pharmacology, paving the way for groundbreaking drug discovery initiatives. Pharmaceutical firms are adopting this transformative approach to distinguish their offerings from those of competitors, while investors are eager to finance the integration of molecular glue technologies into existing pipelines. This synergy fosters rapid market entry for companies and enhances collaboration between academia and the biotech sector, enabling the advancement of glue chemistry and promoting trust among regulators and healthcare professionals.
Restraints in the Global Molecular Glues Market
The Global Molecular Glues market is currently facing certain restraints primarily due to the novel mechanisms of action that these substances introduce. Regulatory agencies are tasked with adapting their evaluation processes, which can result in prolonged review times and a higher volume of required data submissions. This often leads to several rounds of communication between manufacturers and regulatory assessors concerning safety and off-target risks, further extending developmental timelines and increasing costs. Consequently, potential investors may be less inclined to support companies leveraging molecular glue technology. Additionally, manufacturers encounter ambiguity regarding the classification of these products, resulting in uncertain labeling and post-marketing conditions, ultimately hindering commercialization efforts and restricting market access.
Market Trends of the Global Molecular Glues Market
The Global Molecular Glues market is experiencing significant growth driven by the rising adoption of precision protein degrading agents within pharmaceutical development. These molecular glues enable the targeted elimination of previously undruggable proteins, streamlining drug design and enabling faster, more cost-effective development processes. As pharmaceutical companies increasingly prioritize precision medicine, collaborative partnerships between biotech innovators and large pharmaceutical firms are emerging, fostering diverse drug development pipelines. This synergy is likely to expedite the entry of novel therapeutics into clinical trials, enhancing the global landscape of drug treatments focused on intricate disease pathways and ultimately improving patient outcomes worldwide.
Table of Contents
Introduction
- Objectives of the Study
- Market Definition & Scope
Research Methodology
- Research Process
- Secondary & Primary Data Methods
- Market Size Estimation Methods
Executive Summary
- Global Market Outlook
- Key Market Highlights
- Segmental Overview
- Competition Overview
Market Dynamics & Outlook
- Macro-Economic Indicators
- Drivers & Opportunities
- Restraints & Challenges
- Supply Side Trends
- Demand Side Trends
- Porters Analysis & Impact
- Competitive Rivalry
- Threat of Substitute
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers
Key Market Insights
- Key Success Factors
- Market Impacting Factors
- Top Investment Pockets
- Ecosystem Mapping
- Market Attractiveness Index 2025
- PESTEL Analysis
- Regulatory Landscape
Global Molecular Glues Market Size by Target Class & CAGR (2026-2033)
- Market Overview
- E3 Ligase-Based Molecular Glues
- Kinase Molecular Glues
- Transcription Factor Glues
Global Molecular Glues Market Size by Indication & CAGR (2026-2033)
- Market Overview
- Oncology
- Neurological Disorders
- Autoimmune
Global Molecular Glues Market Size by Stage & CAGR (2026-2033)
- Market Overview
- Approved
- Clinical
- Preclinical
Global Molecular Glues Market Size by End-User & CAGR (2026-2033)
- Market Overview
- Pharma & Biotech Companies
- Research Institutes
Global Molecular Glues Market Size by Distribution & CAGR (2026-2033)
- Market Overview
- Hospital Pharmacies
- Specialty Pharmacies
Global Molecular Glues Market Size & CAGR (2026-2033)
- North America (Target Class, Indication, Stage, End-User, Distribution)
- US
- Canada
- Europe (Target Class, Indication, Stage, End-User, Distribution)
- Germany
- Spain
- France
- UK
- Italy
- Rest of Europe
- Asia Pacific (Target Class, Indication, Stage, End-User, Distribution)
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
- Latin America (Target Class, Indication, Stage, End-User, Distribution)
- Mexico
- Brazil
- Rest of Latin America
- Middle East & Africa (Target Class, Indication, Stage, End-User, Distribution)
- GCC Countries
- South Africa
- Rest of Middle East & Africa
Competitive Intelligence
- Top 5 Player Comparison
- Market Positioning of Key Players, 2025
- Strategies Adopted by Key Market Players
- Recent Developments in the Market
- Company Market Share Analysis, 2025
- Company Profiles of All Key Players
- Company Details
- Product Portfolio Analysis
- Company's Segmental Share Analysis
- Revenue Y-O-Y Comparison (2023-2025)
Key Company Profiles
- Novo Nordisk (Degron)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Kymera Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Monte Rosa Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Proxygen GmbH
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Cullinan Oncology
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Neomorph Inc.
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Ajax Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- C4 Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Arvinas Inc.
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Nurix Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Plexium Inc.
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Fog Pharmaceuticals
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Aileron Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- RaNA Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Relay Therapeutics
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Hinova Pharmaceuticals
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Genentech (Roche)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Bristol Myers Squibb
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- AbbVie Inc.
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- AstraZeneca
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
