세계의 베툴린산 시장 : 시장 예측 - 원료별, 형태별, 순도별, 용도별, 최종 사용자별, 지역별 분석(-2032년)

According to Stratistics MRC, the Global Betulinic Acid Market is accounted for $0.10 billion in 2025 and is expected to reach $0.33 billion by 2032 growing at a CAGR of 17.7% during the forecast period. Betulinic acid, a natural pentacyclic triterpenoid compound found mainly in birch bark and various medicinal plants, possesses multiple therapeutic properties such as anticancer, antiviral, antibacterial, and anti-inflammatory effects. It works by triggering apoptosis in tumor cells, suppressing viral growth, and combating oxidative damage. Owing to its bioactive nature and broad pharmacological potential, betulinic acid holds significant promise for future drug research and clinical use.

Market Dynamics:

Driver:

Rising global cancer incidence

As oncology research intensifies, natural anticancer agents are gaining traction for their therapeutic potential. Betulinic acid, known for its selective cytotoxicity against tumor cells, is increasingly being explored in clinical and nutraceutical applications. Aging populations and improved diagnostic capabilities are expanding the demand for targeted cancer therapies. Pharmaceutical and nutraceutical firms are investing in plant-derived molecules to complement conventional treatments. This trend is expected to accelerate betulinic acid adoption across both preventive and therapeutic segments.

Restraint:

Limited availability of raw materials

Seasonal harvesting cycles and geographic limitations restrict access to high-yield raw materials. Sustainable sourcing remains a challenge, especially for manufacturers aiming to scale operations. Regulatory pressures around deforestation and biodiversity conservation further complicate raw material procurement. Smaller producers face cost barriers and logistical hurdles in securing reliable supply chains. These limitations may slow market expansion and increase dependency on synthetic alternatives.

Opportunity:

Advancements in synthesis/extraction technology

Green chemistry approaches and enzymatic techniques are improving yield and purity while reducing environmental impact. Researchers are developing scalable biotechnological processes to overcome raw material constraints. These innovations are lowering production costs and enabling broader commercial applications. Enhanced extraction protocols are also facilitating integration into pharmaceutical formulations and functional foods. As technology matures, it is expected to drive market growth and expand accessibility.

Threat:

Competition from synthetic substitutes

The emergence of synthetic analogs with similar pharmacological profiles poses a competitive threat to natural betulinic acid. These lab-engineered compounds often offer greater consistency, scalability, and regulatory clarity. Pharmaceutical firms may favor synthetic options due to streamlined approval pathways and cost advantages. Advances in medicinal chemistry are enabling the design of more potent derivatives that mimic betulinic acid's anticancer effects. This shift could divert investment away from natural sources and reduce market share for botanical extracts. Without clear differentiation, natural betulinic acid may struggle to maintain its position in high-value applications.

Covid-19 Impact:

The pandemic disrupted global supply chains, delaying raw material procurement and manufacturing timelines for betulinic acid. Lockdowns and labor shortages affected harvesting and processing operations, especially in forest-rich regions. However, the crisis also heightened interest in immune-supportive and antiviral compounds, indirectly benefiting demand. Research into betulinic acid's antiviral properties gained momentum, with some studies exploring its role in COVID-19 adjunct therapies. Post-pandemic strategies now emphasize supply chain resilience and diversified sourcing for botanical actives.

The natural source segment is expected to be the largest during the forecast period

The natural source segment is expected to account for the largest market share during the forecast period, due to its perceived safety, bioavailability, and consumer preference for plant-based ingredients. Betulinic acid derived from birch bark and other botanical sources is favored in nutraceuticals and cosmeceuticals for its anti-inflammatory and anticancer properties. Regulatory bodies are increasingly supporting natural compounds through clean-label initiatives and traditional medicine frameworks. Manufacturers are investing in sustainable harvesting and traceability to meet rising demand. The segment benefits from growing awareness of natural therapeutics and holistic wellness.

The nutraceutical companies segment is expected to have the highest CAGR during the forecast period

Over the forecast period, the nutraceutical companies segment is predicted to witness the highest growth rate, due to rising consumer interest in preventive health and functional supplements. These firms are incorporating betulinic acid into formulations targeting immunity, inflammation, and cancer prevention. The clean-label movement and demand for plant-derived actives are driving innovation in capsules, powders, and beverages. Strategic partnerships with botanical extractors and research institutions are accelerating product development. Regulatory support for dietary supplements is enabling faster market entry and broader distribution.

Region with largest share:

During the forecast period, the Asia Pacific region is expected to hold the largest market share, due to its rich biodiversity, expanding healthcare infrastructure, and strong demand for traditional medicine. Countries like China, India, and South Korea are investing in botanical research and natural product development. Government initiatives are promoting the integration of herbal compounds into mainstream healthcare and nutraceuticals. The region's manufacturing capabilities and cost advantages support large-scale production of betulinic acid. Rising cancer incidence and consumer preference for natural remedies are fueling market growth.

Region with highest CAGR:

Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, owing to its robust R&D ecosystem and growing adoption of plant-based therapeutics. The U.S. and Canada are witnessing increased investment in natural oncology agents and functional ingredients. Regulatory agencies are streamlining pathways for botanical drug approvals and dietary supplements. Consumer awareness around cancer prevention and immune health is driving demand for bioactive compounds like betulinic acid. Innovation in extraction technologies and product formats is expanding market penetration.

Key players in the market

Some of the key players in Betulinic Acid Market include Thermo Fi, Merck KGa, Tokyo Che, Cayman Ch, LGC Group, Selleck Ch, Abcam, ChemFace, Biosynth, MedChem, ChemScen, Chem Imp, Spectrum, Extrasynt, and Aladdin S.

Key Developments:

In October 2025, Thermo Fisher Scientific Inc. announced a definitive agreement to acquire Clario Holdings, Inc., a leading provider of endpoint data solutions for clinical trials, from a shareholder group led by Astorg and Nordic Capital, Novo Holding and Cinven, for $8.875 billion in cash at close plus potential additional earnout and other payments in the future, largely dependent on performance.

In October 2025, Merck has entered into a partnership with Promega Corporation, a global life science solutions and service leader based in Madison, Wisconsin in the US, to co-develop novel technologies that advance drug screening and discovery. The agreement unites Merck's strength in organoids and synthetic chemistry with Promega's market leading assay and reporter technologies.

Sources Covered:

• Natural Source
• Synthetic Source

Forms Covered:

• Powder
• Liquid
• Capsules

Purities Covered:

• >=98% Purity
• <98% Purity

Applications Covered:

• Pharmaceuticals
• Cosmetics & Personal Care
• Food & Nutraceuticals
• Chemical & Research Uses
• Other Applications

End Users Covered:

• Pharmaceutical Companies
• Cosmetic Manufacturers
• Research Laboratories
• Nutraceutical Companies
• Other End Users

Regions Covered:

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • Italy
  • France
  • Spain
  • Rest of Europe
• Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • New Zealand
  • South Korea
  • Rest of Asia Pacific
• South America
  • Argentina
  • Brazil
  • Chile
  • Rest of South America
• Middle East & Africa
  • Saudi Arabia
  • UAE
  • Qatar
  • South Africa
  • Rest of Middle East & Africa

What our report offers:

• Market share assessments for the regional and country-level segments
• Strategic recommendations for the new entrants
• Covers Market data for the years 2024, 2025, 2026, 2028, and 2032
• Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
• Strategic recommendations in key business segments based on the market estimations
• Competitive landscaping mapping the key common trends
• Company profiling with detailed strategies, financials, and recent developments
• Supply chain trends mapping the latest technological advancements

Free Customization Offerings:

All the customers of this report will be entitled to receive one of the following free customization options:

• Company Profiling
  • Comprehensive profiling of additional market players (up to 3)
  • SWOT Analysis of key players (up to 3)
• Regional Segmentation
  • Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
  • Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface

• 2.1 Abstract
• 2.2 Stake Holders
• 2.3 Research Scope
• 2.4 Research Methodology
  • 2.4.1 Data Mining
  • 2.4.2 Data Analysis
  • 2.4.3 Data Validation
  • 2.4.4 Research Approach
• 2.5 Research Sources
  • 2.5.1 Primary Research Sources
  • 2.5.2 Secondary Research Sources
  • 2.5.3 Assumptions

3 Market Trend Analysis

• 3.1 Introduction
• 3.2 Drivers
• 3.3 Restraints
• 3.4 Opportunities
• 3.5 Threats
• 3.6 Application Analysis
• 3.7 End User Analysis
• 3.8 Emerging Markets
• 3.9 Impact of Covid-19

4 Porters Five Force Analysis

• 4.1 Bargaining power of suppliers
• 4.2 Bargaining power of buyers
• 4.3 Threat of substitutes
• 4.4 Threat of new entrants
• 4.5 Competitive rivalry

5 Global Betulinic Acid Market, By Source

• 5.1 Introduction
• 5.2 Natural Source
• 5.3 Synthetic Source

6 Global Betulinic Acid Market, By Form

• 6.1 Introduction
• 6.2 Powder
• 6.3 Liquid
• 6.4 Capsules

7 Global Betulinic Acid Market, By Purity

• 7.1 Introduction
• 7.2 >=98% Purity
• 7.3 <98% Purity

8 Global Betulinic Acid Market, By Application

• 8.1 Introduction
• 8.2 Pharmaceuticals
  • 8.2.1 Anti-cancer Drugs
  • 8.2.2 Anti-HIV Drugs
  • 8.2.3 Anti-inflammatory Drugs
• 8.3 Cosmetics & Personal Care
  • 8.3.1 Anti-aging Products
  • 8.3.2 Skin Repair Formulations
• 8.4 Food & Nutraceuticals
  • 8.4.1 Dietary Supplements
  • 8.4.2 Functional Foods
• 8.5 Chemical & Research Uses
• 8.6 Other Applications

9 Global Betulinic Acid Market, By End User

• 9.1 Introduction
• 9.2 Pharmaceutical Companies
• 9.3 Cosmetic Manufacturers
• 9.4 Research Laboratories
• 9.5 Nutraceutical Companies
• 9.6 Other End Users

10 Global Betulinic Acid Market, By Geography

• 10.1 Introduction
• 10.2 North America
  • 10.2.1 US
  • 10.2.2 Canada
  • 10.2.3 Mexico
• 10.3 Europe
  • 10.3.1 Germany
  • 10.3.2 UK
  • 10.3.3 Italy
  • 10.3.4 France
  • 10.3.5 Spain
  • 10.3.6 Rest of Europe
• 10.4 Asia Pacific
  • 10.4.1 Japan
  • 10.4.2 China
  • 10.4.3 India
  • 10.4.4 Australia
  • 10.4.5 New Zealand
  • 10.4.6 South Korea
  • 10.4.7 Rest of Asia Pacific
• 10.5 South America
  • 10.5.1 Argentina
  • 10.5.2 Brazil
  • 10.5.3 Chile
  • 10.5.4 Rest of South America
• 10.6 Middle East & Africa
  • 10.6.1 Saudi Arabia
  • 10.6.2 UAE
  • 10.6.3 Qatar
  • 10.6.4 South Africa
  • 10.6.5 Rest of Middle East & Africa

11 Key Developments

• 11.1 Agreements, Partnerships, Collaborations and Joint Ventures
• 11.2 Acquisitions & Mergers
• 11.3 New Product Launch
• 11.4 Expansions
• 11.5 Other Key Strategies

12 Company Profiling

• 12.1 Thermo Fisher Scientific
• 12.2 Merck KGaA
• 12.3 Tokyo Chemical Industry (TCI)
• 12.4 Cayman Chemical Company
• 12.5 LGC Group
• 12.6 Selleck Chemicals
• 12.7 Abcam
• 12.8 ChemFaces
• 12.9 Biosynth
• 12.10 MedChemExpress
• 12.11 ChemScene
• 12.12 Chem Impex International
• 12.13 Spectrum Chemical
• 12.14 Extrasynthese
• 12.15 Aladdin Scientific