고칼륨혈증 치료제 시장 예측(-2032년) : 약제 유형별, 투여 경로별, 유통 채널별, 적응증별, 최종사용자별, 지역별 세계 분석

According to Stratistics MRC, the Global Hyperkalemia Drugs Market is accounted for $1.42 billion in 2025 and is expected to reach $3.97 billion by 2032 growing at a CAGR of 15.8% during the forecast period. Hyperkalemia drugs are medications designed to reduce abnormally high potassium levels, which can impair normal heart activity and pose severe health risks. These therapies act by moving potassium back into cells, promoting its removal through urine or the digestive system, or binding it within the gut to limit absorption. Frequently used treatments include diuretics, glucose-assisted insulin, sodium polystyrene sulfonate, and modern potassium-binding formulations. Such drugs play a critical role in restoring safe potassium balance and protecting patients from dangerous cardiac complications.

Market Dynamics:

Driver:

Increased use of RAAS inhibitors

As these drugs elevate potassium levels, clinicians increasingly rely on potassium binders to maintain electrolyte balance. Advancements in therapeutic monitoring tools and e-prescription platforms are supporting wider prescribing confidence. New clinical guidelines promoting long-term RAAS inhibitor use are indirectly amplifying the need for effective hyperkalemia management. Emerging digital adherence technologies are ensuring safer co-administration of hyperkalemia drugs with RAAS inhibitors. With precision medicine growing, combination strategies tailored to individual risk profiles are becoming more common in clinical practice.

Restraint:

Challenges with patient compliance

Many potassium binders require specific dosing schedules, which can reduce long-term compliance. Although new formulations like once-daily or palatable powders are being introduced, consistent patient engagement remains difficult. Digital health tools such as reminder apps and automated follow-up systems are emerging to address adherence gaps. Even with technological support, lifestyle restrictions and gastrointestinal side effects still deter regular use. Limited patient education in some regions also slows the adoption of advanced hyperkalemia therapies.

Opportunity:

Integration of digital health and personalized medicine

Remote monitoring platforms are enabling continuous potassium level tracking, helping clinicians make quicker adjustments to therapy. AI-based risk assessment tools are predicting hyperkalemia episodes more accurately, supporting preventive treatment approaches. Pharmaceutical companies are collaborating with digital health startups to develop integrated care pathways. Personalized medicine strategies, including pharmacogenomic profiling, are improving drug selection and treatment response. This convergence of technology and therapeutics is positioning the market for rapid innovation and expanded patient engagement.

Threat:

Pricing pressure and reimbursement changes

Health authorities are increasingly reviewing the cost-effectiveness of chronic potassium binder therapy. Generic competition is rising, intensifying the pressure on premium-priced branded products. New reimbursement models tied to real-world outcomes are challenging companies to demonstrate consistent clinical benefits. Technology-driven health economic evaluations are becoming central to payer decisions across major markets. Without adaptive pricing strategies, manufacturers may face limited access in cost-sensitive regions.

Covid-19 Impact:

Supply chain interruptions affected drug availability in several regions. However, COVID-19 accelerated telehealth adoption, improving remote treatment oversight for vulnerable patients. Digital prescribing and virtual consultations enhanced continuity of care during lockdowns. Regulatory agencies introduced temporary flexibilities that allowed faster approval of updated formulations and delivery systems. Post-pandemic, health systems are prioritizing digital-first care models and decentralized treatment channels for chronic conditions including hyperkalemia.

The sodium polystyrene sulfonate (SPS) segment is expected to be the largest during the forecast period

The sodium polystyrene sulfonate (SPS) segment is expected to account for the largest market share during the forecast period, due to its long-standing clinical use and cost-effectiveness. Its wide availability across hospitals and retail pharmacies continues to support strong demand. Recent developments in improved powder formulations and easier administration methods are reinforcing its adoption. SPS is frequently utilized in emergency settings due to its familiarity among practitioners. Despite emerging alternatives, its affordability makes it the preferred choice in developing markets.

The home care settings segment is expected to have the highest CAGR during the forecast period

Over the forecast period, the home care settings segment is predicted to witness the highest growth rate, due to increasingly manage chronic disorders outside hospital environments. Growing adoption of remote monitoring devices is enabling safer home-based hyperkalemia management. New portable potassium binders and easy-to-consume formulations are boosting acceptance in home-based care. Telehealth integration is allowing physicians to adjust dosing without requiring in-person visits. Cost savings and convenience are driving patient preference toward home care over traditional clinical settings.

Region with largest share:

During the forecast period, the Asia Pacific region is expected to hold the largest market share, due to its expanding population of patients with diabetes, kidney disorders, and cardiovascular conditions. Rapid healthcare infrastructure development is enhancing access to advanced hyperkalemia treatments. Governments across China, India, and Japan are promoting domestic drug manufacturing and digital health integration. Adoption of mobile health technologies is improving treatment continuity and potassium monitoring. Growing investments in AI-based diagnostic platforms are accelerating early detection of electrolyte disorders.

Region with highest CAGR:

Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, driven by strong technological advancements and early adoption of premium hyperkalemia therapies. The region's robust R&D ecosystem supports continuous innovation in potassium binders and digital therapeutic tools. Healthcare providers are integrating AI-based monitoring systems to optimize chronic condition management. Favourable reimbursement structures are accelerating patient access to newer, high-efficacy treatments. Increasing use of telemedicine and connected devices is enhancing proactive hyperkalemia control.

Key players in the market

Some of the key players in Hyperkalemia Drugs Market include AstraZeneca, CMP Pharma, Vifor Pharma, Keryx Biopharma, Sanofi, OPKO Health, Perrigo Co, Viatris, Ardelyx, Fresenius, Baxter International, scPharmaceuticals, Pfizer, Camber Pharma, and Teva Pharma.

Key Developments:

In July 2025, Sanofi announces the completion of its acquisition of Blueprint Medicines Corporation (Blueprint), adding to its portfolio a commercialized medicine, a promising pipeline, and the expertise of a company specializing in systemic mastocytosis (SM), a rare immunological disease, and other KIT-driven diseases.

In June 2022, CMP Pharma announced that Norliqva(R) (Amlodipine) Oral Solution, 1 mg/mL, the first and only FDA-approved oral liquid solution of the besylate salt of amlodipine, a long-acting calcium channel blocker, is now available. Norliqva was approved by the FDA on February 24, 2022 and is now available through normal retail distribution.

Drug Types Covered:

• Sodium Polystyrene Sulfonate (SPS)
• Patiromer
• Sodium Zirconium Cyclosilicate
• Calcium Polystyrene Sulfonate
• Other Drug Types

Route of Administrations Covered:

• Oral
• Intravenous

Distribution Channels Covered:

• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies

Applications Covered:

• Acute Hyperkalemia
• Chronic Hyperkalemia
• Other Applications

End Users Covered:

• Hospitals
• Clinics
• Ambulatory Surgical Centers
• Home Care Settings
• Other End Users

Regions Covered:

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • Italy
  • France
  • Spain
  • Rest of Europe
• Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • New Zealand
  • South Korea
  • Rest of Asia Pacific
• South America
  • Argentina
  • Brazil
  • Chile
  • Rest of South America
• Middle East & Africa
  • Saudi Arabia
  • UAE
  • Qatar
  • South Africa
  • Rest of Middle East & Africa

What our report offers:

• Market share assessments for the regional and country-level segments
• Strategic recommendations for the new entrants
• Covers Market data for the years 2024, 2025, 2026, 2028, and 2032
• Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
• Strategic recommendations in key business segments based on the market estimations
• Competitive landscaping mapping the key common trends
• Company profiling with detailed strategies, financials, and recent developments
• Supply chain trends mapping the latest technological advancements

Free Customization Offerings:

All the customers of this report will be entitled to receive one of the following free customization options:

• Company Profiling
  • Comprehensive profiling of additional market players (up to 3)
  • SWOT Analysis of key players (up to 3)
• Regional Segmentation
  • Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
  • Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

Table of Contents

1 Executive Summary

2 Preface

• 2.1 Abstract
• 2.2 Stake Holders
• 2.3 Research Scope
• 2.4 Research Methodology
  • 2.4.1 Data Mining
  • 2.4.2 Data Analysis
  • 2.4.3 Data Validation
  • 2.4.4 Research Approach
• 2.5 Research Sources
  • 2.5.1 Primary Research Sources
  • 2.5.2 Secondary Research Sources
  • 2.5.3 Assumptions

3 Market Trend Analysis

• 3.1 Introduction
• 3.2 Drivers
• 3.3 Restraints
• 3.4 Opportunities
• 3.5 Threats
• 3.6 Application Analysis
• 3.7 End User Analysis
• 3.8 Emerging Markets
• 3.9 Impact of Covid-19

4 Porters Five Force Analysis

• 4.1 Bargaining power of suppliers
• 4.2 Bargaining power of buyers
• 4.3 Threat of substitutes
• 4.4 Threat of new entrants
• 4.5 Competitive rivalry

5 Global Hyperkalemia Drugs Market, By Drug Type

• 5.1 Introduction
• 5.2 Sodium Polystyrene Sulfonate (SPS)
• 5.3 Patiromer
• 5.4 Sodium Zirconium Cyclosilicate
• 5.5 Calcium Polystyrene Sulfonate
• 5.6 Other Drug Types

6 Global Hyperkalemia Drugs Market, By Route of Administration

• 6.1 Introduction
• 6.2 Oral
• 6.3 Intravenous

7 Global Hyperkalemia Drugs Market, By Distribution Channel

• 7.1 Introduction
• 7.2 Hospital Pharmacies
• 7.3 Retail Pharmacies
• 7.4 Online Pharmacies

8 Global Hyperkalemia Drugs Market, By Application

• 8.1 Introduction
• 8.2 Acute Hyperkalemia
• 8.3 Chronic Hyperkalemia
• 8.4 Other Applications

9 Global Hyperkalemia Drugs Market, By End User

• 9.1 Introduction
• 9.2 Hospitals
• 9.3 Clinics
• 9.4 Ambulatory Surgical Centers
• 9.5 Home Care Settings
• 9.6 Other End Users

10 Global Hyperkalemia Drugs Market, By Geography

• 10.1 Introduction
• 10.2 North America
  • 10.2.1 US
  • 10.2.2 Canada
  • 10.2.3 Mexico
• 10.3 Europe
  • 10.3.1 Germany
  • 10.3.2 UK
  • 10.3.3 Italy
  • 10.3.4 France
  • 10.3.5 Spain
  • 10.3.6 Rest of Europe
• 10.4 Asia Pacific
  • 10.4.1 Japan
  • 10.4.2 China
  • 10.4.3 India
  • 10.4.4 Australia
  • 10.4.5 New Zealand
  • 10.4.6 South Korea
  • 10.4.7 Rest of Asia Pacific
• 10.5 South America
  • 10.5.1 Argentina
  • 10.5.2 Brazil
  • 10.5.3 Chile
  • 10.5.4 Rest of South America
• 10.6 Middle East & Africa
  • 10.6.1 Saudi Arabia
  • 10.6.2 UAE
  • 10.6.3 Qatar
  • 10.6.4 South Africa
  • 10.6.5 Rest of Middle East & Africa

11 Key Developments

• 11.1 Agreements, Partnerships, Collaborations and Joint Ventures
• 11.2 Acquisitions & Mergers
• 11.3 New Product Launch
• 11.4 Expansions
• 11.5 Other Key Strategies

12 Company Profiling

• 12.1 AstraZeneca
• 12.2 CMP Pharma
• 12.3 Vifor Pharma
• 12.4 Keryx Biopharmaceuticals
• 12.5 Sanofi
• 12.6 OPKO Health
• 12.7 Perrigo Company plc
• 12.8 Viatris
• 12.9 Ardelyx
• 12.10 Fresenius Kabi
• 12.11 Baxter International
• 12.12 scPharmaceuticals
• 12.13 Pfizer
• 12.14 Camber Pharmaceuticals
• 12.15 Teva Pharmaceutical Industries