저체온 치료 시스템 시장 - 세계 산업 규모, 점유율, 동향, 기회, 예측 : 제품별, 용도별, 지역별, 경쟁별(2019-2029년)

Global Therapeutic Hypothermia Systems Market was valued at USD 286.14 million in 2023 and will see an impressive growth in the forecast period at a CAGR of 6.47% through 2029. Therapeutic hypothermia systems are medical devices designed to induce and maintain controlled hypothermia in patients for therapeutic purposes. Hypothermia, defined as a decrease in body temperature below normal physiological levels, is used as a therapeutic intervention to protect vital organs and tissues from ischemic injury, reduce metabolic demand, and mitigate inflammatory responses in various clinical scenarios. Cooling devices are the primary component of therapeutic hypothermia systems and are responsible for lowering the patient's body temperature to the desired therapeutic range. These devices may utilize various cooling methods, including surface cooling pads, water blankets, air-circulating devices, intravascular cooling catheters, or extracorporeal cooling systems, to achieve rapid and controlled cooling. Temperature monitoring and control systems are integrated into therapeutic hypothermia devices to continuously monitor the patient's core body temperature and ensure precise temperature control throughout the cooling and rewarming phases of treatment. These systems provide real-time feedback to healthcare providers, allowing for adjustments to cooling rates and target temperatures based on individual patient responses and clinical indicators.

There is a growing awareness among healthcare professionals regarding the benefits of therapeutic hypothermia in reducing neurological damage and improving survival rates in patients with conditions such as cardiac arrest, stroke, and traumatic brain injury. Increased awareness has led to the incorporation of therapeutic hypothermia protocols into clinical practice guidelines, driving the adoption of hypothermia systems. Continuous advancements in therapeutic hypothermia systems have led to the development of more efficient, user-friendly, and precise devices. Manufacturers are integrating advanced features such as precise temperature control, non-invasive cooling methods, and enhanced patient monitoring capabilities into hypothermia systems, driving their adoption in healthcare facilities. Therapeutic hypothermia is being explored for the treatment of a wide range of medical conditions beyond cardiac arrest and stroke, including neonatal hypoxic-ischemic encephalopathy (HIE), traumatic brain injury, and myocardial infarction. The expanding indications and applications of therapeutic hypothermia systems contribute to the growth of the market.

Key Market Drivers

Growing Awareness of Therapeutic Hypothermia Benefits

Over the years, numerous clinical studies and research initiatives have demonstrated the effectiveness of therapeutic hypothermia in improving outcomes for patients with various conditions, including cardiac arrest, stroke, and traumatic brain injury. As healthcare professionals become increasingly aware of the robust evidence supporting the benefits of therapeutic hypothermia, they are more likely to adopt this intervention in their clinical practice. Leading medical societies and organizations, such as the American Heart Association (AHA) and the European Resuscitation Council (ERC), have incorporated therapeutic hypothermia protocols into their clinical practice guidelines for the management of cardiac arrest and other related conditions. This endorsement from authoritative bodies increases awareness among healthcare providers and encourages the widespread adoption of therapeutic hypothermia. Healthcare institutions, professional societies, and medical education programs are actively involved in raising awareness about the benefits of therapeutic hypothermia through conferences, workshops, webinars, and educational materials. These initiatives help disseminate knowledge about therapeutic hypothermia indications, protocols, and best practices among healthcare professionals.

Patient advocacy groups and organizations play a crucial role in raising awareness about therapeutic hypothermia and its potential benefits for patients and families. By sharing success stories, testimonials, and educational resources, these groups help increase public awareness and understanding of therapeutic hypothermia as a viable treatment option for certain medical conditions. Media coverage of high-profile cases and advancements in medical technology often sparks public interest and discussion around therapeutic hypothermia. Positive media coverage can help raise awareness about therapeutic hypothermia benefits and its role in improving patient outcomes, thereby driving demand for therapeutic hypothermia systems. Continuing medical education programs and professional development opportunities provide healthcare professionals with updated information on therapeutic hypothermia research, guidelines, and clinical applications. These educational resources enable healthcare providers to stay informed about the latest developments in therapeutic hypothermia and incorporate evidence-based practices into their patient care. This factor will help in the development of the Global Therapeutic Hypothermia Systems Market.

Expansion of Indications and Applications

As ongoing research continues to uncover the potential benefits of therapeutic hypothermia in various medical conditions, the range of indications for which hypothermia therapy is applicable continues to expand. Clinical studies and trials investigating the efficacy of therapeutic hypothermia in conditions such as neonatal hypoxic-ischemic encephalopathy (HIE), traumatic brain injury, myocardial infarction, and sepsis are driving the exploration of new applications for hypothermia therapy. Technological advancements in therapeutic hypothermia systems have made them more versatile and adaptable to a wider range of clinical scenarios. Manufacturers are developing innovative cooling devices and methods that allow for precise temperature control and tailored cooling protocols, making therapeutic hypothermia applicable to a broader spectrum of patients and medical conditions. Leading medical societies and organizations are updating their clinical guidelines and recommendations to include therapeutic hypothermia as a treatment option for an expanding list of indications. Endorsement of therapeutic hypothermia by authoritative bodies provides healthcare providers with guidance and support for implementing hypothermia therapy in diverse clinical settings.

Healthcare professionals are becoming more aware of the potential benefits of therapeutic hypothermia beyond its traditional applications in cardiac arrest and stroke. Continuing medical education programs, conferences, and professional development opportunities provide healthcare providers with updated information on emerging indications and best practices for implementing therapeutic hypothermia in clinical practice. There is a growing demand for neuroprotective interventions that can mitigate neurological damage and improve outcomes in patients with conditions such as traumatic brain injury, neonatal HIE, and stroke. Therapeutic hypothermia offers a promising approach to neuroprotection by reducing inflammation, oxidative stress, and secondary brain injury, thereby driving interest and demand for hypothermia systems in neurocritical care settings. The aging population is at increased risk of conditions such as stroke, cardiac arrest, and traumatic brain injury, which can benefit from therapeutic hypothermia therapy. As the global population continues to age, the prevalence of these conditions is expected to rise, driving the demand for therapeutic hypothermia systems to support the management of these patients. This factor will pace up the demand of the Global Therapeutic Hypothermia Systems Market.

Technological Advancements

Modern hypothermia systems feature advanced temperature control mechanisms that allow healthcare providers to precisely regulate and maintain the patient's body temperature within a narrow therapeutic range. This precise temperature control is crucial for optimizing therapeutic outcomes and minimizing the risk of complications. Traditional methods of inducing hypothermia, such as cold intravenous fluids or ice packs, have been largely replaced by non-invasive cooling methods in modern hypothermia systems. Non-invasive cooling techniques, such as surface cooling pads or water blankets, are safer, more comfortable for the patient, and easier to implement in clinical practice. Rapid cooling technologies enable healthcare providers to quickly initiate therapeutic hypothermia in patients following cardiac arrest, stroke, or traumatic brain injury. Rapid cooling systems can achieve target temperatures within a shorter timeframe, thereby reducing the time to therapy initiation and potentially improving patient outcomes. Many hypothermia systems are equipped with integrated monitoring and feedback systems that continuously monitor the patient's temperature, vital signs, and physiological parameters throughout the cooling process. These systems provide real-time feedback to healthcare providers, allowing for timely adjustments to the cooling protocol and early detection of complications.

Some advanced hypothermia systems offer remote monitoring and telemetry capabilities, allowing healthcare providers to monitor patient status and adjust treatment parameters from a centralized location. Remote monitoring enables more efficient use of healthcare resources and facilitates early intervention in case of complications. Modern hypothermia systems allow for customizable cooling protocols based on the patient's specific clinical condition, comorbidities, and individual response to therapy. Healthcare providers can adjust cooling rates, target temperatures, and rewarming strategies to optimize patient outcomes while minimizing the risk of adverse events. Integration of hypothermia systems with electronic health records (EHR) enables seamless documentation, data storage, and retrieval of patient temperature profiles, treatment parameters, and clinical outcomes. Integration with EHR systems streamlines workflow, enhances data accuracy, and facilitates research and quality improvement initiatives. This factor will accelerate the demand of the Global Therapeutic Hypothermia Systems Market.

Key Market Challenges

Concerns Regarding Efficacy and Safety

While therapeutic hypothermia has demonstrated effectiveness in improving outcomes for certain medical conditions such as cardiac arrest and neonatal hypoxic-ischemic encephalopathy (HIE), there may be ongoing debates regarding its efficacy in other clinical scenarios. Some healthcare professionals and stakeholders may express skepticism about the level of evidence supporting the use of therapeutic hypothermia, particularly in conditions with limited research data. Individual patient responses to therapeutic hypothermia can vary depending on factors such as age, comorbidities, severity of illness, and underlying pathophysiology. Achieving optimal therapeutic outcomes with hypothermia therapy requires careful patient selection, precise temperature control, and adherence to standardized treatment protocols. Concerns may arise regarding the variability in treatment response and the potential for suboptimal outcomes in certain patient populations. Therapeutic hypothermia is not without risks, and complications such as electrolyte disturbances, arrhythmias, coagulopathy, and infection may occur during the cooling and rewarming phases of treatment. Healthcare providers must closely monitor patients undergoing therapeutic hypothermia and be prepared to manage potential complications promptly. Concerns about the risk-benefit profile of therapeutic hypothermia may influence clinical decision-making and adoption rates in some healthcare settings.

Logistical Challenges in Implementation

Ensuring the availability and accessibility of therapeutic hypothermia systems in healthcare facilities, particularly in resource-limited settings or rural areas, can be a logistical challenge. Some regions may lack the necessary infrastructure to procure, maintain, and transport hypothermia equipment, limiting access to this life-saving intervention. Implementing therapeutic hypothermia protocols requires specialized training and education for healthcare providers involved in the care of patients undergoing hypothermia therapy. Ensuring that healthcare professionals are adequately trained in the principles, protocols, and best practices associated with therapeutic hypothermia can be challenging, particularly in settings with limited access to training resources and expertise. Effective monitoring and surveillance of patients undergoing therapeutic hypothermia are essential for ensuring treatment efficacy and patient safety. Healthcare facilities must have the necessary infrastructure, personnel, and protocols in place to monitor patient temperature, vital signs, and neurological status continuously throughout the cooling and rewarming phases of treatment.

Key Market Trends

Focus on Patient Safety and Comfort

Therapeutic hypothermia systems are designed to provide precise temperature control while ensuring patient safety. Advanced temperature management features allow healthcare providers to regulate the patient's body temperature within a narrow therapeutic range, minimizing the risk of temperature fluctuations and adverse events. Modern hypothermia systems utilize non-invasive cooling methods such as surface cooling pads, water blankets, or air-circulating devices to induce hypothermia without the need for invasive procedures. Non-invasive cooling methods are more comfortable for patients and reduce the risk of complications associated with invasive techniques, enhancing overall patient safety and satisfaction. Therapeutic hypothermia systems are equipped with integrated monitoring and feedback systems that continuously monitor the patient's temperature, vital signs, and physiological parameters throughout the cooling and rewarming phases of treatment. Real-time feedback enables healthcare providers to adjust treatment parameters and respond promptly to changes in patient status, ensuring optimal patient safety and comfort.

Segmental Insights

Product Insights

The Water Blankets segment is projected to experience rapid growth in the Global Therapeutic Hypothermia Systems Market during the forecast period. Water blankets have been widely recognized for their effectiveness in inducing and maintaining therapeutic hypothermia in patients. They provide a reliable and efficient method for cooling patients to the desired temperature range, which is essential for achieving optimal therapeutic outcomes in conditions such as cardiac arrest, stroke, and neonatal hypoxic-ischemic encephalopathy (HIE). Water blankets offer a non-invasive cooling method compared to invasive techniques such as intravascular cooling catheters. This non-invasive approach reduces the risk of complications associated with invasive procedures, making water blankets a preferred choice for therapeutic hypothermia induction in many clinical settings. Water blankets are relatively easy to use and can be implemented in various healthcare settings, including hospitals, emergency departments, and neonatal intensive care units (NICUs). Their accessibility and simplicity of operation make them suitable for healthcare professionals with diverse levels of training and expertise.

Application Insights

The Neonatal Care segment is projected to experience rapid growth in the Global Therapeutic Hypothermia Systems Market during the forecast period. Neonatal HIE is a leading cause of morbidity and mortality among newborns, resulting from oxygen deprivation during birth. Therapeutic hypothermia has been established as an effective treatment to mitigate brain injury and improve outcomes in neonates with HIE. As awareness about the benefits of therapeutic hypothermia grows, the demand for hypothermia systems in neonatal care settings increases. Advances in neonatal intensive care have improved the survival rates of premature and critically ill newborns. Therapeutic hypothermia is now recognized as a standard of care for eligible neonates with HIE, driving the adoption of hypothermia systems in neonatal units and hospitals worldwide. There is a growing emphasis on neuroprotection strategies in neonatal care to prevent brain injury and promote healthy neurodevelopment in newborns. Therapeutic hypothermia is a well-established neuroprotective therapy that can reduce the severity of brain damage in neonates with HIE, leading to improved long-term outcomes.

Regional Insights

North America emerged as the dominant region in the Global Therapeutic Hypothermia Systems Market in 2023. North America boasts highly advanced healthcare infrastructure, including state-of-the-art medical facilities, well-equipped hospitals, and access to advanced medical technologies. This infrastructure facilitates the adoption and utilization of therapeutic hypothermia systems in clinical practice. The region is a hub for research and development in the healthcare sector. North American companies and academic institutions actively engage in research to develop innovative therapeutic hypothermia systems and improve existing technologies, driving advancements in the field. North America experiences a relatively high incidence of cardiac arrest and stroke compared to other regions. Therapeutic hypothermia is an established treatment modality for these conditions, leading to a higher demand for hypothermia systems in the region.

Key Market Players

Belmont Medical Technologies

BrainCool AB

ZOLL Medical Corporation

Becton, Dickinson, and Company

Stryker Corporation

EM-MED Sp. z o.o.

Life Recovery Systems

Dragerwerk AG & Co. KgaA

Terumo Cardiovascular Systems Corporation

pfm medical gmbh

Report Scope:

In this report, the Global Therapeutic Hypothermia Systems Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Therapeutic Hypothermia Systems Market, By Product:

Cooling Catheters Water Blankets Cool Caps Others

Therapeutic Hypothermia Systems Market, By Application:

Neurology Cardiology Neonatal Care Others

Therapeutic Hypothermia Systems Market, By Region:

North America

United States

Canada

Mexico

Europe

Germany

United Kingdom

France

Italy

Spain

Asia-Pacific

China

Japan

India

Australia

South Korea

South America

Brazil

Argentina

Colombia

Middle East & Africa

South Africa

Saudi Arabia

UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Therapeutic Hypothermia Systems Market.

Available Customizations:

Global Therapeutic Hypothermia Systems market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

• 1.1. Market Definition
• 1.2. Scope of the Market
  • 1.2.1. Markets Covered
  • 1.2.2. Years Considered for Study
  • 1.2.3. Key Market Segmentations

2. Research Methodology

• 2.1. Objective of the Study
• 2.2. Baseline Methodology
• 2.3. Key Industry Partners
• 2.4. Major Association and Secondary Sources
• 2.5. Forecasting Methodology
• 2.6. Data Triangulation & Validation
• 2.7. Assumptions and Limitations

3. Executive Summary

• 3.1. Overview of the Market
• 3.2. Overview of Key Market Segmentations
• 3.3. Overview of Key Market Players
• 3.4. Overview of Key Regions/Countries
• 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Therapeutic Hypothermia Systems Market Outlook

• 5.1. Market Size & Forecast
  • 5.1.1. By Value
• 5.2. Market Share & Forecast
  • 5.2.1. By Product (Cooling Catheters, Water Blankets, Cool Caps, Others)
  • 5.2.2. By Application (Neurology, Cardiology, Neonatal Care, Others)
  • 5.2.3. By Region
  • 5.2.4. By Company (2023)
• 5.3. Market Map

6. North America Therapeutic Hypothermia Systems Market Outlook

• 6.1. Market Size & Forecast
  • 6.1.1. By Value
• 6.2. Market Share & Forecast
  • 6.2.1. By Product
  • 6.2.2. By Application
  • 6.2.3. By Country
• 6.3. North America: Country Analysis
  • 6.3.1. United States Therapeutic Hypothermia Systems Market Outlook
    • 6.3.1.1. Market Size & Forecast
      • 6.3.1.1.1. By Value
    • 6.3.1.2. Market Share & Forecast
      • 6.3.1.2.1. By Product
      • 6.3.1.2.2. By Application
  • 6.3.2. Canada Therapeutic Hypothermia Systems Market Outlook
    • 6.3.2.1. Market Size & Forecast
      • 6.3.2.1.1. By Value
    • 6.3.2.2. Market Share & Forecast
      • 6.3.2.2.1. By Product
      • 6.3.2.2.2. By Application
  • 6.3.3. Mexico Therapeutic Hypothermia Systems Market Outlook
    • 6.3.3.1. Market Size & Forecast
      • 6.3.3.1.1. By Value
    • 6.3.3.2. Market Share & Forecast
      • 6.3.3.2.1. By Product
      • 6.3.3.2.2. By Application

7. Europe Therapeutic Hypothermia Systems Market Outlook

• 7.1. Market Size & Forecast
  • 7.1.1. By Value
• 7.2. Market Share & Forecast
  • 7.2.1. By Product
  • 7.2.2. By Application
  • 7.2.3. By Country
• 7.3. Europe: Country Analysis
  • 7.3.1. Germany Therapeutic Hypothermia Systems Market Outlook
    • 7.3.1.1. Market Size & Forecast
      • 7.3.1.1.1. By Value
    • 7.3.1.2. Market Share & Forecast
      • 7.3.1.2.1. By Product
      • 7.3.1.2.2. By Application
  • 7.3.2. United Kingdom Therapeutic Hypothermia Systems Market Outlook
    • 7.3.2.1. Market Size & Forecast
      • 7.3.2.1.1. By Value
    • 7.3.2.2. Market Share & Forecast
      • 7.3.2.2.1. By Product
      • 7.3.2.2.2. By Application
  • 7.3.3. Italy Therapeutic Hypothermia Systems Market Outlook
    • 7.3.3.1. Market Size & Forecast
      • 7.3.3.1.1. By Value
    • 7.3.3.2. Market Share & Forecast
      • 7.3.3.2.1. By Product
      • 7.3.3.2.2. By Application
  • 7.3.4. France Therapeutic Hypothermia Systems Market Outlook
    • 7.3.4.1. Market Size & Forecast
      • 7.3.4.1.1. By Value
    • 7.3.4.2. Market Share & Forecast
      • 7.3.4.2.1. By Product
      • 7.3.4.2.2. By Application
  • 7.3.5. Spain Therapeutic Hypothermia Systems Market Outlook
    • 7.3.5.1. Market Size & Forecast
      • 7.3.5.1.1. By Value
    • 7.3.5.2. Market Share & Forecast
      • 7.3.5.2.1. By Product
      • 7.3.5.2.2. By Application

8. Asia-Pacific Therapeutic Hypothermia Systems Market Outlook

• 8.1. Market Size & Forecast
  • 8.1.1. By Value
• 8.2. Market Share & Forecast
  • 8.2.1. By Product
  • 8.2.2. By Application
  • 8.2.3. By Country
• 8.3. Asia-Pacific: Country Analysis
  • 8.3.1. China Therapeutic Hypothermia Systems Market Outlook
    • 8.3.1.1. Market Size & Forecast
      • 8.3.1.1.1. By Value
    • 8.3.1.2. Market Share & Forecast
      • 8.3.1.2.1. By Product
      • 8.3.1.2.2. By Application
  • 8.3.2. India Therapeutic Hypothermia Systems Market Outlook
    • 8.3.2.1. Market Size & Forecast
      • 8.3.2.1.1. By Value
    • 8.3.2.2. Market Share & Forecast
      • 8.3.2.2.1. By Product
      • 8.3.2.2.2. By Application
  • 8.3.3. Japan Therapeutic Hypothermia Systems Market Outlook
    • 8.3.3.1. Market Size & Forecast
      • 8.3.3.1.1. By Value
    • 8.3.3.2. Market Share & Forecast
      • 8.3.3.2.1. By Product
      • 8.3.3.2.2. By Application
  • 8.3.4. South Korea Therapeutic Hypothermia Systems Market Outlook
    • 8.3.4.1. Market Size & Forecast
      • 8.3.4.1.1. By Value
    • 8.3.4.2. Market Share & Forecast
      • 8.3.4.2.1. By Product
      • 8.3.4.2.2. By Application
  • 8.3.5. Australia Therapeutic Hypothermia Systems Market Outlook
    • 8.3.5.1. Market Size & Forecast
      • 8.3.5.1.1. By Value
    • 8.3.5.2. Market Share & Forecast
      • 8.3.5.2.1. By Product
      • 8.3.5.2.2. By Application

9. South America Therapeutic Hypothermia Systems Market Outlook

• 9.1. Market Size & Forecast
  • 9.1.1. By Value
• 9.2. Market Share & Forecast
  • 9.2.1. By Product
  • 9.2.2. By Application
  • 9.2.3. By Country
• 9.3. South America: Country Analysis
  • 9.3.1. Brazil Therapeutic Hypothermia Systems Market Outlook
    • 9.3.1.1. Market Size & Forecast
      • 9.3.1.1.1. By Value
    • 9.3.1.2. Market Share & Forecast
      • 9.3.1.2.1. By Product
      • 9.3.1.2.2. By Application
  • 9.3.2. Argentina Therapeutic Hypothermia Systems Market Outlook
    • 9.3.2.1. Market Size & Forecast
      • 9.3.2.1.1. By Value
    • 9.3.2.2. Market Share & Forecast
      • 9.3.2.2.1. By Product
      • 9.3.2.2.2. By Application
  • 9.3.3. Colombia Therapeutic Hypothermia Systems Market Outlook
    • 9.3.3.1. Market Size & Forecast
      • 9.3.3.1.1. By Value
    • 9.3.3.2. Market Share & Forecast
      • 9.3.3.2.1. By Product
      • 9.3.3.2.2. By Application

10. Middle East and Africa Therapeutic Hypothermia Systems Market Outlook

• 10.1. Market Size & Forecast
  • 10.1.1. By Value
• 10.2. Market Share & Forecast
  • 10.2.1. By Product
  • 10.2.2. By Application
  • 10.2.3. By Country
• 10.3. MEA: Country Analysis
  • 10.3.1. South Africa Therapeutic Hypothermia Systems Market Outlook
    • 10.3.1.1. Market Size & Forecast
      • 10.3.1.1.1. By Value
    • 10.3.1.2. Market Share & Forecast
      • 10.3.1.2.1. By Product
      • 10.3.1.2.2. By Application
  • 10.3.2. Saudi Arabia Therapeutic Hypothermia Systems Market Outlook
    • 10.3.2.1. Market Size & Forecast
      • 10.3.2.1.1. By Value
    • 10.3.2.2. Market Share & Forecast
      • 10.3.2.2.1. By Product
      • 10.3.2.2.2. By Application
  • 10.3.3. UAE Therapeutic Hypothermia Systems Market Outlook
    • 10.3.3.1. Market Size & Forecast
      • 10.3.3.1.1. By Value
    • 10.3.3.2. Market Share & Forecast
      • 10.3.3.2.1. By Product
      • 10.3.3.2.2. By Application

11. Market Dynamics

• 11.1. Drivers
• 11.2. Challenges

12. Market Trends & Developments

• 12.1. Merger & Acquisition (If Any)
• 12.2. Product Launches (If Any)
• 12.3. Recent Developments

13. Porter's Five Forces Analysis

• 13.1. Competition in the Industry
• 13.2. Potential of New Entrants
• 13.3. Power of Suppliers
• 13.4. Power of Customers
• 13.5. Threat of Substitute Product

14. Competitive Landscape

• 14.1. Belmont Medical Technologies
  • 14.1.1. Business Overview
  • 14.1.2. Company Snapshot
  • 14.1.3. Products & Services
  • 14.1.4. Financials (As Reported)
  • 14.1.5. Recent Developments
  • 14.1.6. Key Personnel Details
  • 14.1.7. SWOT Analysis
• 14.2. BrainCool AB
• 14.3. ZOLL Medical Corporation
• 14.4. Becton, Dickinson and Company
• 14.5. Stryker Corporation
• 14.6. EM-MED Sp. z o.o.
• 14.7. Life Recovery Systems
• 14.8. Dragerwerk AG & Co. KgaA
• 14.9. Terumo Cardiovascular Systems Corporation
• 14.10.pfm medical gmbh

15. Strategic Recommendations

16. About Us & Disclaimer