세계의 인공 슬관절 치환술 시장 규모 : 유형별, 방법식별, 소재별, 최종사용자별, 지역 범위별 및 예측

Total Knee Replacement Market Size And Forecast

Total Knee Replacement Market size was valued at USD 9.92 Billion in 2024 and is projected to reach USD 15.37 Billion by 2032, growing at a CAGR of 6.2% from 2026 to 2032.

The Total Knee Replacement Market, also known as the total knee arthroplasty (TKA) market, is a segment of the medical device industry that focuses on the design, manufacturing, and sale of artificial knee joint implants and related surgical equipment.

The market is defined by the following key aspects:

Surgical Procedure: It revolves around the surgical procedure of total knee arthroplasty (TKA), where a damaged or diseased knee joint is replaced with artificial components. This is most commonly performed to relieve pain and restore mobility in patients with severe osteoarthritis, but is also used for other conditions like rheumatoid arthritis, bone trauma, or complex fractures.

Products: The market includes a range of products, segmented by:

Procedure Type: Primary (first time surgery), Partial (unicompartmental), and Revision (to replace a failed implant).

Implant Components: Femoral, Tibial, and Patellar components.

Material: Common materials include metal on plastic, ceramic on plastic, and others.

Fixation Method: Implants can be cemented, cementless (press fit), or hybrid.

Design: Different designs such as fixed bearing, mobile bearing, and posterior stabilized are available.

Market Drivers: The market is primarily driven by:

Aging Population: The global rise in the geriatric population, who are more susceptible to degenerative joint diseases like osteoarthritis.

Increasing Prevalence of Joint Disorders: A growing number of cases of osteoarthritis, rheumatoid arthritis, and other conditions that necessitate knee replacement.

Technological Advancements: The development of more durable and advanced implants, as well as the increasing adoption of technology assisted surgeries like robotic assisted procedures and 3D printing for customized implants.

Lifestyle Factors: Rising obesity rates, which place increased strain on knee joints, and the growing incidence of sports injuries.

Key Players: The market is highly competitive and is dominated by major medical technology companies that specialize in orthopedic devices.

In essence, the Total Knee Replacement Market is a growing and dynamic sector of the healthcare industry, driven by demographic shifts and technological innovation, all aimed at addressing the increasing need for effective and long lasting solutions for debilitating knee conditions.

Global Total Knee Replacement Market Drivers

The Total Knee Replacement (TKR) market is experiencing steady growth worldwide, fueled by demographic changes, rising chronic disease prevalence, and advancements in surgical technologies. As healthcare infrastructure improves and awareness about effective joint replacement therapies increases, more patients are opting for TKR procedures to restore mobility and improve quality of life. Below are the major drivers shaping the market's growth trajectory.

Rising Prevalence of Osteoarthritis: One of the primary drivers of the Total Knee Replacement Market is the increasing prevalence of osteoarthritis, the most common degenerative joint disease. Osteoarthritis significantly affects knee joints, leading to pain, stiffness, and reduced mobility, thereby creating a strong demand for surgical interventions. According to global health organizations, millions of people are diagnosed with osteoarthritis each year, and this number continues to rise due to sedentary lifestyles, obesity, and longer life expectancies. The escalating burden of osteoarthritis directly translates into a higher adoption of TKR procedures, positioning this factor as a leading growth catalyst for the market.

Aging Global Population: The global population is aging rapidly, and this demographic shift is significantly influencing the Total Knee Replacement Market. Older adults are more prone to joint deterioration and age related musculoskeletal conditions, making them prime candidates for knee replacement surgeries. Countries with large elderly populations, such as Japan, Germany, and the United States, are witnessing a surge in TKR procedures. Furthermore, advances in surgical techniques and implant longevity have made knee replacement surgeries a viable option even for patients in advanced age groups. This demographic trend is expected to sustain long term growth in the market.

Technological Advancements in Knee Replacement Procedures: Continuous innovation in medical technology is another critical driver of the Total Knee Replacement Market. Developments such as robotic assisted surgeries, minimally invasive procedures, and patient specific implants are improving surgical accuracy, reducing recovery times, and enhancing long term outcomes. Robotics and computer assisted navigation systems are increasingly adopted by hospitals and orthopedic centers to deliver personalized and precise treatments. These technological innovations not only improve patient satisfaction but also encourage more surgeons and patients to opt for advanced TKR solutions, thereby driving market growth.

Improved Implant Designs and Materials: Advancements in biomaterials and implant design are fueling the adoption of Total Knee Replacement procedures. Modern implants are designed to mimic natural knee movement, provide greater flexibility, and ensure durability, which enhances overall patient outcomes. The use of advanced materials such as highly cross linked polyethylene and titanium alloys has significantly improved the longevity of knee implants, reducing the need for revision surgeries. As manufacturers continue to innovate with biocompatible and wear resistant implants, patient confidence in TKR solutions is rising, further accelerating demand.

Increasing Healthcare Expenditure and Infrastructure Development: The rise in global healthcare spending, coupled with infrastructure development, is significantly boosting the Total Knee Replacement Market. Governments and private healthcare providers are investing heavily in advanced surgical facilities, orthopedic clinics, and specialized rehabilitation centers. This has increased access to quality care and reduced surgical waiting times in many regions. Additionally, health insurance coverage for knee replacement surgeries in developed economies and emerging markets has made these procedures more affordable, thereby encouraging greater patient adoption.

Growing Patient Awareness and Lifestyle Changes: Rising awareness about the benefits of Total Knee Replacement surgeries is also driving market demand. Patients are becoming more informed about treatment options through online platforms, healthcare campaigns, and orthopedic specialists. As lifestyles change, particularly with increasing obesity and sedentary habits contributing to knee disorders, individuals are seeking long term solutions like TKR to regain mobility and independence. Enhanced awareness about minimally invasive techniques and shorter hospital stays has further increased patient confidence in opting for knee replacement procedures.

Global Total Knee Replacement Market Restraints

The total knee replacement (TKR) market is a significant and growing segment of the global medical device industry, driven by an aging population, rising obesity rates, and the increasing prevalence of osteoarthritis. However, despite these strong growth drivers, the market faces several significant restraints that challenge its expansion and impact patient access and outcomes. Understanding these barriers is crucial for all stakeholders, from manufacturers and healthcare providers to patients and policymakers. This article explores the primary factors that currently restrain the Total Knee Replacement Market.

High Cost of Knee Replacement Procedures: One of the most significant barriers to the widespread adoption of total knee replacement is the substantial financial burden it places on patients and healthcare systems. The high cost encompasses more than just the surgical procedure itself, including preoperative consultations, sophisticated implant devices, hospital stays, and extensive postoperative rehabilitation. In many developing and low income countries, patients are often unable to afford these procedures due to limited or non existent health insurance coverage. Even in developed nations, where insurance is more common, rising healthcare costs and high deductibles can still create a significant financial strain, deterring many from pursuing a medically necessary surgery. The high price tag associated with advanced, robot assisted surgeries and personalized 3D printed implants further exacerbates this issue, making cutting edge technology less accessible to the general population.

Risk of Surgical Complications and Revision Surgeries: While total knee replacement is a highly effective procedure, it is not without risks. Patients and healthcare providers are constantly concerned about the potential for surgical complications, which can include infections, blood clots, nerve damage, and long term implant loosening. These complications not only compromise the patient's well being but also lead to additional medical expenses and the need for more complex, costly, and painful revision surgeries. The risk of implant failure over time is a major deterrent for younger and more active patients, as it increases their lifetime probability of needing multiple revision procedures. This concern over long term outcomes and the potential for complications continues to restrain the market by influencing patient decision making and contributing to a more cautious approach to TKR.

Limited Accessibility in Developing Regions: The Total Knee Replacement Market faces a significant geographical disparity, with limited accessibility in many developing and emerging economies. This is primarily due to a combination of factors, including underdeveloped healthcare infrastructure, a critical shortage of skilled orthopedic surgeons, and a lack of access to advanced surgical technologies and high quality implants. Rural and remote populations are particularly affected, as they often lack the means to travel to specialized urban centers for treatment. This gap in healthcare access restricts the market's potential for global expansion and perpetuates a major disparity in treatment options, leaving millions of individuals with debilitating knee conditions without a viable solution.

Stringent Regulatory Approvals and Compliance Issues: The orthopedic medical device industry, including the TKR market, operates under a highly stringent regulatory framework. Regulatory bodies like the U.S. FDA and the EU's MDR require extensive clinical trials and safety evaluations for all new implants and technologies. While these regulations are essential for ensuring patient safety, they also create significant hurdles for manufacturers. The lengthy and costly approval timelines can delay the market entry of innovative products, slowing down the adoption of new, potentially better implants. Furthermore, the high costs of research, development, and compliance can be prohibitive for smaller companies, leading to market consolidation and potentially limiting competition and innovation.

Challenges with Postoperative Rehabilitation and Recovery: The recovery process following a total knee replacement surgery is a crucial but often challenging aspect of the patient journey. It typically involves a lengthy period of intensive physical therapy and rehabilitation to regain mobility, strength, and function. For many patients, particularly the elderly, adherence to these demanding regimens can be difficult due to physical limitations, lack of a strong support system, or financial constraints related to ongoing therapy sessions. The prospect of a prolonged and sometimes painful recovery can be a significant psychological barrier, discouraging individuals from undergoing the surgery despite their pain and disability. These postoperative challenges represent a notable restraint on market growth as they affect patient satisfaction and word of mouth referrals.

Shortage of Skilled Orthopedic Surgeons: A critical global restraint on the TKR market is the shortage of qualified and experienced orthopedic surgeons. Performing total knee replacement requires a high level of specialized expertise, which is often concentrated in major urban hospitals. In many regions, the number of trained professionals is insufficient to meet the rising demand for TKR procedures, leading to long waiting lists and a potential compromise in the quality of care. This shortage is further exacerbated by the aging demographic of the surgical workforce, with a significant number of experienced surgeons nearing retirement. Without a sufficient pipeline of new, skilled surgeons, the market's ability to expand and serve the growing patient population will continue to be hindered.

Global Total Knee Replacement Market Segmentation Analysis

The Total Knee Replacement Market is segmented On The basis Of Type, Procedure, Material, End User, and Geography.

Total Knee Replacement Market, By Type

Primary

Partial

Revision

Based on Type, the Total Knee Replacement Market is segmented into Primary, Partial, and Revision. At VMR, we observe that the Primary subsegment is overwhelmingly dominant, holding a substantial majority of the market share, with estimates placing its revenue contribution at over 70% in 2024. This dominance is driven by a confluence of powerful market forces. The most significant driver is the global rise in the geriatric population, which directly correlates with the increasing prevalence of age related conditions like osteoarthritis and rheumatoid arthritis. This is particularly evident in developed regions like North America, which commanded over 40% of the total market revenue in 2024, thanks to a large aging population, well established healthcare infrastructure, and favorable reimbursement policies. Industry trends such as the adoption of robotic assisted surgery and patient specific implants are also propelling the primary segment's growth by enhancing surgical precision, improving patient outcomes, and shortening recovery times.

The second most dominant subsegment is Revision knee replacement. This segment plays a crucial, though smaller, role in the market, with a projected CAGR of 5.28% from 2024 to 2032. Its growth is primarily fueled by the increasing number of primary surgeries performed over the past two decades. As patients live longer and maintain more active lifestyles, the longevity of their initial implants is tested, necessitating re operations due to implant wear, loosening, or infection. This trend is particularly notable in North America and Europe, where a high volume of primary procedures has created a large pool of patients who will eventually require revision surgeries. Technological advancements in implant materials and surgical techniques are also driving this segment's growth, as manufacturers focus on developing more durable and specialized components to address the complexities of revision procedures.

The Partial subsegment, while a smaller contributor, is the fastest growing segment in certain regions, particularly in the Asia Pacific market. It caters to a specific, niche patient population where damage is confined to a single compartment of the knee, allowing for a less invasive, bone preserving approach. While its adoption is limited by strict patient selection criteria and a steep learning curve for surgeons, ongoing innovations in mobile bearing implants and robotic assisted techniques are expected to expand its future potential and adoption rates, offering a viable alternative for select patients.

Total Knee Replacement Market, By Procedure

Traditional

Minimally Invasive

Computer assisted

Based on Procedure, the Total Knee Replacement Market is segmented into Traditional, Minimally Invasive, and Computer assisted. At VMR, we observe that the Traditional subsegment, encompassing conventional manual surgical techniques, continues to hold a dominant market position, accounting for over 80% of all procedures in 2024. Its sustained dominance is primarily due to a well established clinical track record and widespread familiarity among surgeons, particularly in North America and Europe where it remains the standard of care. This procedure is generally more cost effective than its high tech counterparts, making it the preferred option in many hospitals and healthcare systems, especially in emerging markets where the high capital investment for advanced equipment is a significant barrier.

The second most dominant subsegment is the Computer assisted procedure, which includes both navigated and robotic assisted surgeries. While its market share is currently smaller, it is the fastest growing segment, projected to expand at an impressive CAGR of 11% between 2024 and 2034. This segment is driven by a strong desire for enhanced surgical precision, improved implant placement, and reduced revision rates, which are critical for long term patient outcomes. The integration of advanced technologies like AI and robotics in surgical planning and execution offers surgeons real time data and haptic feedback, fundamentally reshaping the industry. North America leads the adoption of these technologies, with key players like Stryker and Zimmer Biomet heavily investing in their robotic platforms.

The Minimally Invasive subsegment, though smaller, plays a crucial role as a bridge between traditional and high tech procedures. It focuses on smaller incisions and less tissue disruption to reduce post operative pain and shorten hospital stays. While it does not require the capital investment of computer assisted surgery, its effectiveness is highly dependent on surgeon skill and patient selection. This segment is gaining traction in specific orthopedic clinics and ambulatory surgery centers where shorter recovery times and outpatient procedures are a priority. Its future potential lies in its ability to offer a middle ground-providing some of the benefits of advanced surgery without the associated costs, thereby supporting market growth in a more cost conscious environment.

Total Knee Replacement Market, By Material

Metal Alloys

Ceramics

Polymers

Based on Material, the Total Knee Replacement Market is segmented into Metal Alloys, Ceramics, and Polymers. At VMR, we find that metal alloys, particularly the Metal on Plastic combination, are the dominant subsegment, accounting for nearly 50% of the market share in 2024. Their dominance is rooted in a proven clinical history of over two decades, exceptional durability, and high mechanical strength, which are essential for withstanding the immense forces exerted on the knee joint. The key drivers include the rising global prevalence of osteoarthritis and a growing elderly population, which collectively create a high volume of demand for reliable and long lasting implants. Regionally, North America remains the primary consumer, driven by a large geriatric population, robust healthcare infrastructure, and favorable reimbursement policies.

The second most dominant subsegment is Ceramics, which, while holding a smaller market share, is the fastest growing material segment, projected to grow at a CAGR of over 10% through 2030. This growth is spurred by an increasing focus on addressing the limitations of metal alloys, specifically concerns about metal hypersensitivity and the wear and tear of metal on polyethylene interfaces. Ceramic on ceramic or ceramic on polyethylene implants offer superior wear resistance, which can reduce the need for revision surgeries, making them a preferred choice for younger, more active patients. This trend is gaining significant traction in Europe and Asia Pacific, where there is a rising demand for high performance, long lasting orthopedic solutions.

Polymers, primarily used as the articulating polyethylene component in combination with metal or ceramics, play a critical supporting role. Innovations in highly cross linked polyethylene have significantly improved their wear resistance and longevity. Although they are not used as stand alone implants, their role as the crucial bearing surface ensures the smooth function and durability of the entire implant, making them an indispensable component of nearly every knee replacement system.

Total Knee Replacement Market, By End User

Hospitals

Ambulatory Surgical Centers

Orthopedic Clinics

Based on End User, the Total Knee Replacement Market is segmented into Hospitals, Ambulatory Surgical Centers (ASCs), and Orthopedic Clinics. At VMR, we observe that hospitals represent the dominant end user subsegment, capturing over 60% of the market share in 2024. This segment's enduring dominance is attributed to several key factors, including their comprehensive infrastructure, the availability of advanced medical technologies and specialized surgical teams, and their capacity to manage complex procedures and patient comorbidities. Hospitals are the primary destination for traditional, more complex, and revision knee replacement surgeries, especially for high risk patients. The rising geriatric population and the increasing prevalence of severe osteoarthritis and rheumatoid arthritis globally are continuously driving patient volume to hospital settings, particularly in established markets like North America and Europe, which have sophisticated healthcare systems.

The second most dominant subsegment is Ambulatory Surgical Centers (ASCs). While holding a smaller market share, this segment is the fastest growing end user, with a projected CAGR of over 9% through 2030. The rapid growth of ASCs is driven by a fundamental shift in healthcare toward cost effectiveness, patient convenience, and shorter recovery times. Improvements in surgical techniques, particularly the adoption of minimally invasive and robotic assisted procedures, have made it safer and more efficient to perform knee replacements in an outpatient setting. Favorable changes in reimbursement policies, such as the inclusion of total knee arthroplasty on Medicare's list of approved ASC procedures, have significantly accelerated this migration. North America, especially the U.S., is a leader in this trend, with a robust network of ASCs offering lower costs and a more streamlined patient experience.

Orthopedic Clinics play a crucial, but more specialized, role within the market. Their function is typically focused on patient diagnostics, non surgical management, and pre and post operative care. While they do not perform a high volume of knee replacement surgeries themselves, they are vital referral sources and support systems that facilitate the overall patient journey, from initial diagnosis to long term rehabilitation. As the market continues to evolve, these clinics are becoming more integrated with surgical centers and hospitals, ensuring a seamless continuum of care for patients.

Total Knee Replacement Market, By Geography

North America

Europe

Asia Pacific

Rest of the World

United States Total Knee Replacement Market

The United States is the largest and most dominant market for total knee replacement. Its leading position is shaped by a confluence of demographic, economic, and technological factors.

Market Dynamics and Growth Drivers: A primary driver is the high prevalence of osteoarthritis and obesity. The U.S. has a high incidence of these conditions, and excess body weight places immense stress on knee joints, accelerating the need for replacement surgeries. The market also benefits from a robust healthcare infrastructure, with numerous orthopedic clinics and hospitals equipped for these procedures. Favorable insurance coverage and reimbursement policies further fuel market growth by making these surgeries more accessible to a large patient population.

Current Trends: The market is characterized by a strong trend towards technological innovation. This includes the increasing adoption of robotic assisted surgery and 3D printed, patient specific implants, which promise greater surgical precision, faster recovery, and improved long term outcomes. There is also a notable shift of procedures to ambulatory surgical centers (ASCs) for cost effectiveness and a growing demand for revision arthroplasty due to younger patients receiving initial replacements.

Europe Total Knee Replacement Market

Europe represents the second largest market for knee replacement, defined by its aging population and a focus on balancing technological adoption with healthcare cost management.

Market Dynamics and Growth Drivers: The key driver is the large and growing geriatric population across the continent, particularly in Western European countries like Germany, the UK, and France. This demographic trend is directly linked to the rising incidence of age related joint conditions. The market is also driven by rising healthcare expenditures and a well established healthcare infrastructure in these developed nations.

Current Trends: European countries are increasingly adopting advanced technologies such as patient specific implants and robot assisted surgery to improve outcomes and reduce the need for revisions. However, a major dynamic is the continuous effort to contain healthcare costs, which can influence the adoption rate of new, expensive technologies. The European market is also seeing a rise in awareness campaigns by government and health organizations to encourage the early detection and treatment of musculoskeletal disorders.

Asia Pacific Total Knee Replacement Market

The Asia Pacific region is the fastest growing market for total knee replacement, presenting immense opportunities due to its vast population and evolving healthcare landscape.

Market Dynamics and Growth Drivers: The rapid growth is fueled by a combination of a growing elderly population and increasing healthcare expenditure in key countries like China, India, Japan, and South Korea. As disposable incomes rise, more people can afford advanced medical procedures. Additionally, a growing awareness of orthopedic disorders and the availability of advanced treatments are key drivers. The region is also becoming a hub for medical tourism, attracting international patients with high quality, often more affordable, surgical options.

Current Trends: The market is undergoing a rapid transition towards adopting modern technologies, including robotic and computer assisted surgery. While total knee replacement remains the largest segment, the market is also witnessing a significant rise in the adoption of partial knee replacement surgeries. India, in particular, is projected to have one of the highest growth rates in the region.

Latin America Total Knee Replacement Market

The Latin American market is characterized by moderate but steady growth, driven by improving healthcare infrastructure and expanding access to care.

Market Dynamics and Growth Drivers: Key drivers include a rising prevalence of arthritis and an aging population. Improving economic conditions and government investments in healthcare infrastructure are making advanced medical procedures more accessible. The expansion of the middle class with higher disposable incomes also plays a crucial role, as more individuals can afford to pay for procedures that were previously out of reach. The market also benefits from the entry of major international medical device companies, which are expanding their distribution networks in the region.

Current Trends: The market is seeing a growing adoption of both total and partial knee replacement procedures. There is an increased focus on using modern implants and surgical techniques to improve patient outcomes. Countries like Brazil and Argentina are leading the market in the region, with a growing demand for advanced surgical solutions.

Middle East & Africa Total Knee Replacement Market

The Middle East & Africa (MEA) region is an emerging market with significant growth potential, albeit with varying dynamics across its sub regions.

Market Dynamics and Growth Drivers: Growth in the Middle East is primarily driven by substantial government investments in healthcare infrastructure. Countries within the Gulf Cooperation Council (GCC), such as Saudi Arabia and the UAE, are actively positioning themselves as medical tourism destinations. This has led to the development of world class medical facilities and a greater demand for advanced orthopedic procedures. In Africa, the market is more constrained, but countries like South Africa have more developed healthcare systems.

Current Trends: The MEA market is seeing a rise in demand for total knee replacement procedures, driven by a growing incidence of musculoskeletal disorders and an aging population. The region shows a growing interest in technologically advanced devices and surgical techniques. However, challenges like the high cost of procedures and a shortage of skilled professionals in some areas can restrain growth. Saudi Arabia and South Africa are expected to lead the growth in their respective sub regions.

Key Players

• Zimmer, Inc.
• DePuy Synthes
• Stryker
• Smith & Nephew
• Exactech, Inc.
• Corin Group
• Aesculap Implants Systems LL
• Medacta International
• Allegra Orthopaedics Limited
• Kinamed, Inc.

TABLE OF CONTENTS

1 INTRODUCTION

• 1.1 MARKET DEFINITION
• 1.2 MARKET SEGMENTATION
• 1.3 RESEARCH TIMELINES
• 1.4 ASSUMPTIONS
• 1.5 LIMITATIONS

2 RESEARCH METHODOLOGY

• 2.1 DATA MINING
• 2.2 SECONDARY RESEARCH
• 2.3 PRIMARY RESEARCH
• 2.4 SUBJECT MATTER EXPERT ADVICE
• 2.5 QUALITY CHECK
• 2.6 FINAL REVIEW
• 2.7 DATA TRIANGULATION
• 2.8 BOTTOM-UP APPROACH
• 2.9 TOP-DOWN APPROACH
• 2.10 RESEARCH FLOW
• 2.11 DATA AGE GROUPS

3 EXECUTIVE SUMMARY

• 3.1 GLOBAL TOTAL KNEE REPLACEMENT MARKET OVERVIEW
• 3.2 GLOBAL TOTAL KNEE REPLACEMENT MARKET ESTIMATES AND FORECAST (USD MILLION)
• 3.3 GLOBAL TOTAL KNEE REPLACEMENT MARKET ECOLOGY MAPPING
• 3.4 COMPETITIVE ANALYSIS: FUNNEL DIAGRAM
• 3.5 GLOBAL TOTAL KNEE REPLACEMENT MARKET ABSOLUTE MARKET OPPORTUNITY
• 3.6 GLOBAL TOTAL KNEE REPLACEMENT MARKET ATTRACTIVENESS ANALYSIS, BY REGION
• 3.7 GLOBAL TOTAL KNEE REPLACEMENT MARKET ATTRACTIVENESS ANALYSIS, BY VEST TYPE
• 3.8 GLOBAL TOTAL KNEE REPLACEMENT MARKET ATTRACTIVENESS ANALYSIS, BY GENDER
• 3.9 GLOBAL TOTAL KNEE REPLACEMENT MARKET ATTRACTIVENESS ANALYSIS, BY AGE GROUP
• 3.10 GLOBAL TOTAL KNEE REPLACEMENT MARKET GEOGRAPHICAL ANALYSIS (CAGR %)
• 3.11 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY VEST TYPE (USD MILLION)
• 3.12 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY GENDER (USD MILLION)
• 3.13 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY AGE GROUP(USD MILLION)
• 3.14 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY GEOGRAPHY (USD MILLION)
• 3.15 FUTURE MARKET OPPORTUNITIES

4 MARKET OUTLOOK

• 4.1 GLOBAL TOTAL KNEE REPLACEMENT MARKET EVOLUTION
• 4.2 GLOBAL TOTAL KNEE REPLACEMENT MARKET OUTLOOK
• 4.3 MARKET DRIVERS
• 4.4 MARKET RESTRAINTS
• 4.5 MARKET TRENDS
• 4.6 MARKET OPPORTUNITY
• 4.7 PORTER'S FIVE FORCES ANALYSIS
  • 4.7.1 THREAT OF NEW ENTRANTS
  • 4.7.2 BARGAINING POWER OF SUPPLIERS
  • 4.7.3 BARGAINING POWER OF BUYERS
  • 4.7.4 THREAT OF SUBSTITUTE GENDERS
  • 4.7.5 COMPETITIVE RIVALRY OF EXISTING COMPETITORS
• 4.8 VALUE CHAIN ANALYSIS
• 4.9 PRICING ANALYSIS
• 4.10 MACROECONOMIC ANALYSIS

5 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY PRODUCT TYPE

• 5.1 OVERVIEW
• 5.2 PRIMARY KNEE REPLACEMENT SYSTEMS
• 5.3 REVISION KNEE REPLACEMENT SYSTEMS
• 5.4 PARTIAL KNEE REPLACEMENT SYSTEMS

6 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY IMPLANT TYPE

• 6.1 OVERVIEW
• 6.2 FIXED-BEARING IMPLANTS
• 6.3 MOBILE-BEARING IMPLANTS
• 6.4 MEDIAL PIVOT IMPLANTS
• 6.5 OTHERS

7 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY PROCEDURE

• 7.1 OVERVIEW
• 7.2 TOTAL KNEE ARTHROPLASTY
• 7.3 PARTIAL KNEE ARTHROPLASTY
• 7.4 REVISION KNEE ARTHROPLASTY

8 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY END-USE

• 8.1 OVERVIEW
• 8.2 HOSPITALS
• 8.3 ORTHOPEDIC CLINICS
• 8.4 AMBULATORY SURGICAL CENTERS

9 MARKET, BY GEOGRAPHY

• 9.1 OVERVIEW
• 9.2 NORTH AMERICA
  • 9.2.1 U.S.
  • 9.2.2 CANADA
  • 9.2.3 MEXICO
• 9.3 EUROPE
  • 9.3.1 GERMANY
  • 9.3.2 U.K.
  • 9.3.3 FRANCE
  • 9.3.4 ITALY
  • 9.3.5 SPAIN
  • 9.3.6 REST OF EUROPE
• 9.4 ASIA PACIFIC
  • 9.4.1 CHINA
  • 9.4.2 JAPAN
  • 9.4.3 INDIA
  • 9.4.4 REST OF ASIA PACIFIC
• 9.5 LATIN AMERICA
  • 9.5.1 BRAZIL
  • 9.5.2 ARGENTINA
  • 9.5.3 REST OF LATIN AMERICA
• 9.6 MIDDLE EAST AND AFRICA
  • 9.6.1 UAE
  • 9.6.2 SAUDI ARABIA
  • 9.6.3 SOUTH AFRICA
  • 9.6.4 REST OF MIDDLE EAST AND AFRICA

10 COMPETITIVE LANDSCAPE

• 9.1 OVERVIEW
• 9.2 KEY DEVELOPMENT STRATEGIES
• 9.3 COMPANY REGIONAL FOOTPRINT
• 9.4 ACE MATRIX
  • 9.4.1 ACTIVE
  • 9.4.2 CUTTING EDGE
  • 9.4.3 EMERGING
  • 9.4.4 INNOVATORS

11 COMPANY PROFILES

• 11.1 OVERVIEW
• 11.2 ZIMMER, INC.
• 11.3 DEPUY SYNTHES
• 11.4 STRYKER
• 11.5 SMITH & NEPHEW
• 11.6 EXACTECH, INC.
• 11.7 CORIN GROUP
• 11.8 AESCULAP IMPLANTS SYSTEMS LLC
• 11.9 MEDACTA INTERNATIONAL
• 11.10 ALLEGRA ORTHOPAEDICS LIMITED
• 11.11 KINAMED, INC