세계의 단백질 치료제 시장 : 제품별, 용도별, 지역별 - 규모, 산업 동향, 기회 분석, 예측(2025-2033년)

The market is currently experiencing dynamic and robust growth, with its valuation reaching US$ 229.8 billion in 2024. This upward trajectory is expected to continue strongly over the coming years, with projections indicating that the market will nearly double to an estimated valuation of US$ 426.8 billion by 2033. This expansion corresponds to a compound annual growth rate (CAGR) of 7.12% during the forecast period from 2025 to 2033, reflecting sustained and accelerating demand across various therapeutic areas.

Several key factors are driving this impressive growth. One of the primary catalysts is the groundbreaking wave of regulatory approvals in the field of neurology, which has introduced innovative biologic therapies targeting complex neurological conditions. These new treatments are addressing previously unmet medical needs, offering hope for patients with chronic and often debilitating diseases. In parallel, there has been a significant surge in prescriptions for GLP-1 agonists, particularly for metabolic disorders such as diabetes and obesity.

Noteworthy Market Developments

Competitive strategies within the protein therapeutics market are centered around the development of highly targeted therapies such as monoclonal antibodies (mAbs), substantial investments in research and development (R&D), and securing regulatory support to expedite the approval of new biologics. Companies are increasingly focusing on precision medicine approaches that enable treatments tailored to specific disease mechanisms, with monoclonal antibodies exemplifying this trend due to their ability to target molecular pathways.

A notable example of this dynamic occurred in October 2025 when abla Bio entered into a multi-year research collaboration with Takeda aimed at advancing the AI-driven design of protein therapeutics. This partnership illustrates the growing intersection between artificial intelligence and biotechnology, as companies leverage computational tools to accelerate the discovery and optimization of novel protein drugs. As part of the agreement, abla Bio received an upfront payment and ongoing research funding, with the potential to earn success-based payments exceeding $1 billion, underscoring the high stakes and financial commitment involved in cutting-edge protein therapeutics development.

Further highlighting the financial vitality of the sector, in June 2025, Signify Bio, a pioneering biotechnology company focused on harnessing the human body for in situ production of protein therapeutics, announced an oversubscribed $15 million initial financing round. This funding round was led by Actium Group and featured participation from prominent investors such as the Gates Foundation Strategic Investment Fund, Danaher Ventures LLC (a subsidiary of Danaher Corporation), Eli Lilly and Company, and BrightEdge, the venture capital arm of the American Cancer Society (ACS).

Core Growth Drivers

The rapid expansion of cell and gene therapies (CGT) is creating a substantial new demand for highly specialized proteins within the broader protein therapeutics market. These advanced therapies rely heavily on protein-based components, particularly in the form of vectors used to deliver genetic material into patients' cells. By early 2024, there were over 420 gene therapies in clinical trials that utilize protein-based vectors, illustrating the critical role proteins play in the development and function of these innovative treatments.

Emerging Opportunity Trends

The future of the plasma protein therapeutics market is marked by significant growth driven by both an expanding supply chain for raw materials and a rising clinical demand for advanced therapies. A critical factor supporting this growth is the rapid expansion of plasma collection networks, which are essential to meet the increasing therapeutic needs of patients worldwide. In the United States alone, major plasma collectors such as CSL Plasma and Octapharma are scaling their operations significantly. CSL Plasma, for example, has expanded its network to more than 300 collection centers, reflecting the importance of increasing plasma availability to support the production of plasma-derived medicines.

Barriers to Optimization

The high cost associated with the development and manufacturing of protein therapeutics presents a significant barrier that may impede market growth. Developing these advanced biologic drugs involves complex processes, including extensive research, clinical trials, and stringent regulatory requirements, all of which contribute to substantial financial investments. These costs are further amplified during manufacturing, as producing protein-based therapies requires specialized facilities, sophisticated technology, and strict quality control measures to ensure safety and efficacy. The cumulative effect of these expenses often results in high prices for end products, which can limit patient accessibility.

Detailed Market Segmentation

By Product Type, the monoclonal antibodies segment holds a dominant position within the protein therapeutics market, commanding an impressive 51% share that reflects a fundamental shift toward precision medicine. This segment's prominence underscores how monoclonal antibodies have become essential tools for targeting specific disease mechanisms with high accuracy, offering tailored treatments that improve patient outcomes across a range of conditions. Their growing importance is evident in the regulatory landscape, where in 2024, monoclonal antibodies accounted for 13 out of the 16 new biologics approved by the U.S. Food and Drug Administration (FDA).

By Application, the metabolic disorders segment commands an impressive 33% share of the protein therapeutics market, a dominance that directly stems from the global epidemic of diabetes and obesity. These chronic illnesses affect hundreds of millions of people worldwide, creating an urgent need for effective treatments. Protein-based drugs have emerged as vital tools in managing these conditions, offering targeted approaches that help control disease progression and improve patient outcomes. Their growing importance is reflected in the substantial volume of prescriptions written over recent years, underscoring both patient demand and clinical reliance on these therapies.

Segment Breakdown

By Product

• Monoclonal Antibodies
• Insulin
• Fusion Protein
• Erythropoietin
• Interferon
• Human Growth Hormone
• Follicle Stimulating Hormone

By Applications

• Metabolic Disorders
• Immunologic Disorders
• Hematological Disorders
• Cancer
• Hormonal Disorders
• Genetic Disorders

By Region

• North America
• The US
• Canada
• Mexico
• Europe
• Western Europe
• The UK
• Germany
• France
• Italy
• Spain
• Rest of Western Europe
• Eastern Europe
• Poland
• Russia
• Rest of Eastern Europe
• Asia Pacific
• China
• India
• Japan
• Australia and New Zealand
• South Korea
• ASEAN
• Rest of Asia Pacific
• Middle East and Africa
• Saudi Arabia
• South Africa
• UAE
• Rest of MEA
• South America
• Argentina
• Brazil
• Rest of South America

Geography Breakdown

• North America firmly holds a commanding position in the protein therapeutics market, accounting for over 42% of the global market share. This leadership is rooted in a combination of cutting-edge research capabilities and a well-organized administrative framework that supports innovation and regulatory efficiency. The region's stronghold is further reinforced by advancements in regulatory processes that streamline the development and approval of protein-based therapies.
• North America's innovation ecosystem is vibrant and prolific, with an overwhelming number of early-stage developments in protein therapeutics underway. The U.S. Food and Drug Administration's Center for Biologics Evaluation and Research (CBER) oversees thousands of ongoing Investigational New Drug (IND) programs focused on biologics, reflecting the depth and breadth of research activity in the region. This robust pipeline highlights the continuous efforts to discover and develop novel protein-based treatments, addressing a wide range of medical conditions.

Leading Market Participants

• Bayer AG
• Bristol-Myers Squibb
• Daiichi Sankyo Company
• Abbott
• Sanofi
• Thermo Fisher Scientific Inc.
• Genzyme Corporation
• AbbVie Inc.
• Leadiant Biosciences
• Takeda Pharmaceutical Company Limited
• Other Prominent Players

Table of Content

Chapter 1. Research Framework

• 1.1 Research Objective
• 1.2 Product Overview
• 1.3 Market Segmentation

Chapter 2. Research Methodology

• 2.1 Qualitative Research
  • 2.1.1 Primary & Secondary Sources
• 2.2 Quantitative Research
  • 2.2.1 Primary & Secondary Sources
• 2.3 Breakdown of Primary Research Respondents, By Region
• 2.4 Assumption for the Study
• 2.5 Market Size Estimation
• 2.6. Data Triangulation

Chapter 3. Executive Summary: Global Protein Therapeutics Market

Chapter 4. Global Protein Therapeutics Market Overview

• 4.1. Industry Value Chain Analysis
  • 4.1.1. Material Provider
  • 4.1.2. Manufacturer
  • 4.1.3. Distributor
  • 4.1.4. Process Type
• 4.2. Industry Outlook
• 4.3. PESTLE Analysis
• 4.4. Porter's Five Forces Analysis
  • 4.4.1. Bargaining Power of Suppliers
  • 4.4.2. Bargaining Power of Buyers
  • 4.4.3. Threat of Substitutes
  • 4.4.4. Threat of New Entrants
  • 4.4.5. Degree of Competition
• 4.5. Market Dynamics and Trends
  • 4.5.1. Growth Drivers
  • 4.5.2. Restraints
  • 4.5.3. Challenges
  • 4.5.4. Key Trends
• 4.6. Market Growth and Outlook
  • 4.6.1. Market Revenue Estimates and Forecast (US$ Bn), 2020 - 2033
  • 4.6.2. Price Trend Analysis
• 4.7. Competition Dashboard
  • 4.7.1. Market Concentration Rate
  • 4.7.2. Company Market Share Analysis (Value %), 2024
  • 4.7.3. Competitor Mapping & Benchmarking
• 4.8. Actionable Insights (Analyst Recommendation's)

Chapter 5. Global Protein Therapeutics Market Analysis, By Product

• 5.1. Key Insights
• 5.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 5.2.1. Monoclonal Antibodies
  • 5.2.2. Insulin
  • 5.2.3. Fusion Protein
  • 5.2.4. Erythropoietin
  • 5.2.5. Interferon
  • 5.2.6. Human Growth Hormone
  • 5.2.7. Follicle Stimulating Hormone

Chapter 6. Global Protein Therapeutics Market Analysis, By Applications

• 6.1. Key Insights
• 6.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 6.2.1. Metabolic Disorders
  • 6.2.2. Immunologic Disorders
  • 6.2.3. Hematological Disorders
  • 6.2.4. Cancer
  • 6.2.5. Hormonal Disorders
  • 6.2.6. Genetic Disorders

Chapter 7. Global Protein Therapeutics Market Analysis, By Region

• 7.1. Key Insights
• 7.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 7.2.1. North America
    • 7.2.1.1. The U.S.
    • 7.2.1.2. Canada
    • 7.2.1.3. Mexico
  • 7.2.2. Europe
    • 7.2.2.1. Western Europe
      • 7.2.2.1.1. The UK
      • 7.2.2.1.2. Germany
      • 7.2.2.1.3. France
      • 7.2.2.1.4. Italy
      • 7.2.2.1.5. Spain
      • 7.2.2.1.6. Rest of Western Europe
    • 7.2.2.2. Eastern Europe
      • 7.2.2.2.1. Poland
      • 7.2.2.2.2. Russia
      • 7.2.2.2.3. Rest of Eastern Europe
  • 7.2.3. Asia Pacific
    • 7.2.3.1. China
    • 7.2.3.2. India
    • 7.2.3.3. Japan
    • 7.2.3.4. South Korea
    • 7.2.3.5. Australia & New Zealand
    • 7.2.3.6. ASEAN
    • 7.2.3.7. Rest of Asia Pacific
  • 7.2.4. Middle East & Africa
    • 7.2.4.1. UAE
    • 7.2.4.2. Saudi Arabia
    • 7.2.4.3. South Africa
    • 7.2.4.4. Rest of MEA
  • 7.2.5. South America
    • 7.2.5.1. Argentina
    • 7.2.5.2. Brazil
    • 7.2.5.3. Rest of South America

Chapter 8. North America Protein Therapeutics Market Analysis

• 8.1. Key Insights
• 8.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 8.2.1. By Product
  • 8.2.2. By Applications
  • 8.2.3. By Country

Chapter 9. Europe Protein Therapeutics Market Analysis

• 9.1. Key Insights
• 9.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 9.2.1. By Product
  • 9.2.2. By Applications
  • 9.2.3. By Country

Chapter 10. Asia Pacific Protein Therapeutics Market Analysis

• 10.1. Key Insights
• 10.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 10.2.1. By Product
  • 10.2.2. By Applications
  • 10.2.3. By Country

Chapter 11. Middle East and Africa Protein Therapeutics Market Analysis

• 11.1. Key Insights
• 11.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 11.2.1. By Product
  • 11.2.2. By Applications
  • 11.2.3. By Country

Chapter 12. South America Protein Therapeutics Market Analysis

• 12.1. Key Insights
• 12.2. Market Size and Forecast, 2020 - 2033 (US$ Bn)
  • 12.2.1. By Product
  • 12.2.2. By Applications
  • 12.2.3. By Country

Chapter 13. Company Profile (Company Overview, Financial Matrix, Key Product landscape, Key Personnel, Key Competitors, Contact Address, and Business Strategy Outlook)

• 13.1. Bayer AG
• 13.2. Bristol-Myers Squibb
• 13.3. Daiichi Sankyo Company
• 13.4. Abbott
• 13.5. Sanofi
• 13.6. Thermo Fisher Scientific Inc.
• 13.7. Genzyme Corporation
• 13.8. AbbVie Inc.
• 13.9. Leadiant Biosciences
• 13.10. Takeda Pharmaceutical Company Limited
• 13.11. Other Prominent Players

Chapter 14. Annexure

• 14.1. List of Secondary Sources
• 14.2. Key Country Markets- Macro Economic Outlook/Indicators