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심상성 사마귀 : 시장 인사이트, 역학 및 시장 예측(2036년)

Common Warts - Market Insight, Epidemiology, and Market Forecast - 2036

발행일: | 리서치사: 구분자 DelveInsight | 페이지 정보: 영문 105 Pages | 배송안내 : 2-10일 (영업일 기준)

    
    
    




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심상성 사마귀에 대한 인사이트와 동향

  • DelveInsight의 분석에 따르면, 2025년 시점에서 주요 시장(미국, EU 4개국(독일, 프랑스, 이탈리아, 스페인), 영국 및 일본)의 심상성 사마귀 시장 규모는 약 10억 달러인 것으로 나타났습니다.
  • 심상성 사마귀(verruca vulgaris)는 저위험형 인유두종바이러스(HPV : 1형, 2형, 4형, 27형, 57형)가 피부의 미세한 찰과상을 통해 침투함으로써 발생하는 양성 표피 증식입니다. 이들은 경계가 뚜렷한 과각화성 구진으로 나타나며, 일반적으로 손, 손가락, 발에 발생하고, 소아, 청소년 및 면역결핍 환자에서 유병률이 높습니다.
  • HPV는 각질세포의 과다 증식과 면역 회피를 유발하여, 치료에도 불구하고 병변이 지속되거나 재발하는 원인이 됩니다. 감염은 직접 접촉이나 오염된 표면(매개물)을 통해 발생하며, 특히 공동 생활 환경에서 높은 발생률과 재발률을 보입니다.
  • 진단은 주로 임상적이며, 특징적인 형태나 혈전화된 모세혈관('검은 점')을 바탕으로 이루어지지만, 생검은 비정형 사례나 치료에 반응하지 않는 사례로 제한됩니다.
  • 치료법으로는 외용 각질 용해제(살리실산)와 냉동요법이 주류를 이루고 있으며, 구하기 쉽고 효과가 입증되었기 때문에 이 두 가지가 여전히 1차 치료법으로 자리 잡고 있습니다. 난치성 사례에서는 파괴 요법(전기 수술, 레이저 치료, 외과적 절제)이 사용되지만, 통증, 흉터, 그리고 높은 비용과 같은 제약이 있습니다. 면역요법(예 : 병변 내 칸디다 항원 주입)은 근본적인 바이러스성 원인을 표적으로 삼아 재발률을 낮춤으로써 주목을 받고 있습니다.
  • 심상성 사마귀의 경우, 현재 FDA 승인을 받았으며 특정한 적응증을 가진 처방약이 존재하지 않으며, 이는 피부과 분야에서 뚜렷한 치료 공백을 반영하고 있습니다. 사용 가능한 치료법은 표적을 정확히 겨냥한 바이러스 특이적 약물이 아니라, 각질 용해제(예 : 살리실산)나 냉동요법 등의 시술적 개입과 같은 비특이적 접근법으로 거의 한정되어 있습니다. 이는 근본적인 HPV 감염을 직접 치료하고, 장기적인 완치율과 재발 억제율을 개선하는, 표준화되고 근거에 기반한 약물 요법에 대한 미충족 의료 수요를 여실히 드러내고 있습니다.
  • CANDIN, YCANTH(VP-102), KNP2002 등을 포함한 개발 중인 파이프라인은 효능, 내약성, 편의성을 향상시키기 위해 면역 조절 작용 및 항바이러스 작용의 기전에 초점을 맞추고 있습니다.
  • 이 시장은 대량 생산이 가능하면서도 비용이 저렴한 치료법과, 틈새시장에서 높은 부가가치를 지닌 시술이 공존한다는 점이 특징이며, 지속적인 치료 성과를 가져다주는 혁신적이고 환자 친화적인 치료법의 기회를 창출하고 있습니다.

'심상성 사마귀' 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘 등 현재의 치료 현황에 대한 종합적인 분석을 제공합니다. 본 보고서에서는 심상성 사마귀 환자의 부담 추이, 수익 및 시장 점유율 추이, 피크 시기의 환자 점유율 및 치료 도입률 분석을 평가함과 동시에, 세계 각 지역의 시장 규모에 대한 상세한 평가 및 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제시하고 있습니다. 본 보고서에서는 심상성 사마귀와 관련된 주요 미충족 요구 사항을 부각시키고, 경쟁 구도 및 임상 상황을 분석하여 고부가가치의 성장 기회를 밝혀내는 한편, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.

심상성 사마귀 시장을 주도하는 주요 요인

  • 표적 치료 및 면역 치료의 부상

개발 파이프라인은 HPV를 표적으로 하는 치료법 및 면역 매개형 치료로 전환되고 있으며, CANDIN, YCANTH(VP-102), KNP2002와 같은 약물은 효능 향상과 재발 감소를 목표로 하고 있어, 병변 파괴를 넘어선 패러다임의 전환을 시사하고 있습니다.

  • 높은 유병률과 재발로 인한 부담

심상성 사마귀는 특히 소아나 면역결핍 환자에서 유병률과 재발률이 높아, 이로 인해 반복적인 치료가 필요하며 시장 수요를 지속시키고 있습니다.

  • 더 안전하고 환자 친화적인 치료법에 대한 수요

통증, 흉터, 여러 차례의 시술 등 현행 치료법의 한계로 인해, 최소침습적이고 내약성이 높으며 편의성이 뛰어난 치료법에 대한 수요가 증가하고 있습니다.

심상성 사마귀에 대한 이해와 치료 알고리즘

심상성 사마귀의 개요와 진단

심상성 사마귀(verruca vulgaris)는 HPV 감염(가장 흔한 것은 1형, 2형, 4형, 27형, 57형)에 의해 유발되는 양성 표피 증식이며, 피부의 미세한 찰과상을 통해 침투합니다. 손, 손가락, 손톱 주변, 발에 거친 과각화성 구진으로 나타나며, 종종 통증이나 외모상의 고민을 유발합니다.

형태와 발생 부위에 따라 심상성 사마귀, 발바닥 사마귀, 편평 사마귀, 손발톱 주위 사마귀로 분류됩니다. 직접 접촉이나 매개체를 통해 감염되기 때문에 전염성이 매우 강한 것이 특징입니다. 양성이며 자연 치유되는 질환이긴 하지만, HPV 감염의 지속이나 면역 회피로 인해 재발률이 높으며, 특히 소아, 사춘기 청소년, 면역결핍 환자에게서 많이 나타나 전 세계적으로 큰 질병 부담을 주고 있습니다.

심상성 사마귀의 진단

심상성 사마귀(verruca vulgaris)의 진단은 주로 임상 소견에 근거합니다. 구체적으로는 거칠고 과각화가 나타난 구진이라는 특징적인 외관이나, 손, 손가락, 손톱 주위, 발에 전형적으로 분포한다는 점 등을 들 수 있습니다. 중요한 임상적 특징으로는, 피부경 검사나 상세한 관찰을 통해 확인되는 혈전화된 모세혈관('검은 점')을 들 수 있습니다.

비정형 사례, 재발 사례 또는 치료 저항성 사례에서는 피부경검사가 혈관 패턴을 시각화하는 데 도움이 됩니다. 또한, 다른 병변을 배제하고 HPV 관련 병리 소견을 확인하기 위해 피부 생검이 시행되기도 합니다. 진단은 주로 시각적이며 비침습적이며, 검사실에서 검사를 받아야 하는 경우는 거의 없습니다. 적절한 치료법을 선택하고 불필요한 침습적 시술을 피하기 위해서는 정확하고 조기적인 인식이 중요합니다.

평평한 사마귀의 진단과 치료

심상성 사마귀(verruca vulgaris)의 치료는 주로 병변을 제거하고 재발을 억제하는 것을 목적으로 합니다. 1차 치료법으로는 살리실산 외용 및 냉동요법(액체 질소)이 있으며, 구하기 쉽고 효과가 입증되어 널리 사용되고 있지만, 대부분의 경우 여러 차례의 치료 세션이 필요합니다.

난치성 증례의 경우, 트리클로로아세트산(TCA), 전기 수술, 레이저 치료, 외과적 절제 등 진료소 내 시술을 통해 병변을 제거합니다. 특히 재발성 또는 다발성 사마귀의 경우, HPV에 대한 숙주의 면역 반응을 자극하기 위해 병변 내 칸디다 항원 주입이나 기타 적응증 외 약물을 이용한 면역요법이 점점 더 많이 사용되고 있습니다. 새로운 치료법으로는 면역 조절 작용 및 항바이러스 작용에 초점을 맞춘 CANDIN(Nielsen BioSciences/마루호), YCANTH(VP-102)(Verrica Pharmaceuticals/토리이 약품), KNP2002(KinoPharma/이와키제약) 등이 있으며, 이들은 기초가 되는 바이러스 감염을 표적으로 삼아 치료 성과 향상을 목표로 하고 있습니다.

심상성 사마귀의 역학

심상성 사마귀의 역학 분석 및 예측에 관한 주요 조사 결과

  • DelveInsight사의 추산에 따르면, 2025년 주요 7개국에서 심상성 사마귀 환자 총수는 약 1,506만 3,000명이었습니다.
  • 가장 높은 발병률은 소아 및 청소년에게서 나타나지만, 면역결핍 환자에서도 발생률과 지속률이 현저히 높습니다.
  • 피부 사마귀를 유발하는 HPV 감염은 주로 저위험형인 1형, 2형, 4형, 27형, 57형과 관련이 있으며, 이들 유형이 사마귀 사례의 대부분을 차지합니다.
  • 유럽에서는 사마귀가 유병률 41.3%로 가장 흔한 피부 질환으로 확인되었으며, 이는 이 지역의 피부과 의료에 큰 부담이 되고 있음을 여실히 보여주고 있습니다.
  • 발바닥 사마귀는 체중이 실리는 부위에 가해지는 압력이나 통증으로 인해 증상이 나타나기 쉬우므로, 임상 현장에서 상당한 비율을 차지하고 있습니다.
  • 심상성 사마귀는 양성 종양이지만, 자연 치유율이 높은(대부분의 경우 1-2년 이내에 치유됨) 질환임에도 불구하고, HPV가 면역 반응을 회피하기 때문에 상당 비율에서 지속되거나 재발합니다.
  • 2차 분석에 따르면, 사마귀는 전 세계적으로 흔한 질환으로, 인구의 약 10%가 이 질환을 앓고 있으며, 학령기 아동의 경우 유병률이 10-20%로 상승합니다. 영유아기에는 드물지만, 학령기에 접어들면서 증가하여 12세에서 16세 사이에 정점을 이루며, 면역 억제 상태에 있는 사람이나 육류 취급자에게서 더 빈번하게 관찰됩니다.

심상성 사마귀 시장의 전망

심상성 사마귀 시장은 시술 중심의 병변 파괴 치료 패러다임에서 근본적인 HPV 감염을 표적으로 하는 면역 매개형 및 기전 기반 치료법으로 점차 전환되고 있습니다. 살리실산 외용제나 냉동요법은 구하기 쉽고 친숙하다는 점 때문에 여전히 1차 치료법이자 진료소에서의 표준 치료법으로 주류를 이루고 있지만, 통증, 재발, 치료 순응도 등의 측면에서 한계가 있어, 보다 효과적이고 환자에게 부담이 적은 대체 요법에 대한 수요가 증가하고 있습니다. 이를 통해 장기적인 치유율 향상을 목표로 하는 면역요법 및 항바이러스 요법 개발을 위한 견고한 기반이 마련되고 있습니다.

CANDIN(닐슨 바이오사이언스 및 마루호), YCANTH(VP-102)(베리카 파마슈티컬스 및 토리이 약품), KNP2002(키노파마 및 이와키 제약)와 같은 신규 파이프라인 후보의 등장은 면역 조절, 항바이러스, 및 표적 치료와 같은 기전으로의 전환을 반영하고 있으며, 이들은 재발 억제 및 치료 부담 경감을 통해 치료 접근법을 재정의할 것으로 기대되고 있습니다.

지역별로 보면 치료 보급률이 높고, 피부과 의료 인프라가 잘 갖춰져 있으며, 첨단 치료법이 조기에 도입된 덕분에 미국이 최대 시장이 되었습니다. 한편, 유럽 5개국과 일본은 피부과 의료에 대한 접근성 개선과 치료 선택지에 대한 인식 제고에 힘입어 꾸준한 성장을 이어가고 있습니다.

전반적으로, 이 시장은 높은 유병률, 지속적인 재발로 인한 부담, 그리고 지속적인 치료법에 대한 미충족 수요에 힘입어 예측 기간 동안 꾸준히 성장할 것으로 예상됩니다. 또한, 내약성 향상, 편의성 향상, 그리고 HPV를 표적으로 하는 작용 기전에 초점을 맞춘 혁신이 향후 성장을 견인할 것으로 전망됩니다.

  • 외용 요법 : 살리실산 등의 각질 용해제가 포함되어 있습니다. 이들 치료법은 확고한 임상적 근거, 일반의약품으로서의 접근성, 그리고 합리적인 가격 덕분에 여전히 1차 치료법으로 자리 잡고 있습니다. 이들은 과각화 조직을 서서히 박리함으로써 작용하여, 인유두종바이러스(HPV)에 감염된 세포를 제거할 수 있게 합니다. 그 밖의 외용 요법으로는, 피부 사마귀에 대해 적응증 외로 사용되며, 국소적인 항바이러스 면역을 자극하는 면역 반응 조절제인 이미키모드가 있습니다.
  • 비약물적 치료 : 냉동요법(액체 질소), 전기 수술, 소파술, 레이저 절제술, 덕트 테이프 요법 등의 폐쇄 요법이 포함됩니다. 이러한 방법은 특히 증상이 동반된 사례나 난치성 사례에서 병변을 신속하게 제거하기 위해 널리 사용되고 있지만, 불편감을 유발할 수 있으며 재발률에도 편차가 있습니다.
  • 면역요법 : CANDIN(칸디다 항원) 등의 병변 내 항원 요법이 포함됩니다. 이들은 HPV에 감염된 각화 세포에 대한 전신성 세포성 면역 반응을 자극합니다. 이러한 치료법은 다발성, 재발성 또는 치료 저항성 사마귀를 가진 환자들에게서 사용이 확대되고 있으며, 치료 부위뿐만 아니라 원격 부위의 병변도 제거할 수 있다는 장점이 있습니다.
  • 신규 및 개발 중인 치료법 : 개발 상황은 지속적으로 변화하고 있으며, 효능, 내약성 및 재발 예방을 개선하기 위한 후보 약물이 개발되고 있습니다. 주요 후보 약물로는 VP-102(표준화된 칸타리딘 외용제), CANDIN(더 광범위한 피부과 용도를 위해 평가가 진행 중인), 그리고 VBP-245 및 KNP2002와 같은 초기 단계의 프로그램이 포함됩니다. 이러한 치료법은 수포 형성 작용, 면역 조절 작용 또는 항바이러스 작용의 기전을 활용하여, 기존의 치료법에 비해 보다 일관되고 통제된 치료 결과를 가져옵니다.

전반적으로, 일반적인 사마귀에 대한 현재의 치료 패러다임은 주로 외용 각질 용해제나 파괴적 시술에 중점을 두고 있으며, 이러한 치료법은 바이러스를 근절하기보다는 병변을 제거하는 데 초점을 맞추고 있습니다. 그러나 면역요법 전략과 표준화된 개발 중인 약물을 통해 치료 방식은 표적을 더욱 명확히 하고, 지속성이 높으며, 재발을 줄이는 치료법으로 전환될 것으로 기대됩니다.

자주 묻는 질문

  • 2025년 심상성 사마귀 시장 규모는 어떻게 예측되나요?
  • 심상성 사마귀의 주요 원인은 무엇인가요?
  • 심상성 사마귀의 치료법은 어떤 것들이 있나요?
  • 심상성 사마귀의 유병률은 어떻게 되나요?
  • 심상성 사마귀의 진단 방법은 무엇인가요?
  • 심상성 사마귀 시장의 성장 요인은 무엇인가요?

목차

제1장 주요 인사이트

제2장 소개

제3장 심상성 사마귀 : 주요 요약

제4장 주요 사건

제5장 심상성 사마귀 : 역학 및 시장 조사 방법

제6장 심상성 사마귀 : 시장 개요

제7장 심상성 사마귀 : 질환 배경과 개요

제8장 심상성 사마귀 : 역학 및 환자 인구

제9장 심상성 사마귀 : 환자 경과

제10장 새로운 치료법

제11장 심상성 사마귀 : 주요 7개국 분석

제12장 심상성 사마귀 : 미충족 수요

제13장 심상성 사마귀 : SWOT 분석

제14장 심상성 사마귀 : KOL의 견해

제15장 심상성 사마귀 : 시장 진입 및 상환

제17장 부록

제18장 DelveInsight의 서비스 내용

제19장 면책사항

제20장 DelveInsight 소개

KSM 26.07.20

Common Warts Insights and Trends

  • According to DelveInsight's analysis, common warts market size was found to be ~USD 1000 million in the leading markets (the United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan) in 2025.
  • Common warts (verruca vulgaris) are benign epidermal proliferations caused by low-risk human papillomavirus (HPV) types (1, 2, 4, 27, and 57), entering through micro-abrasions in the skin. They present as well-demarcated, hyperkeratotic papules, commonly affecting the hands, fingers, and feet, with higher prevalence in children, adolescents, and immunocompromised individuals.
  • HPV drives keratinocyte hyperproliferation and immune evasion, contributing to persistence and recurrence despite treatment. Transmission occurs via direct contact or contaminated surfaces (fomites), supporting high incidence and recurrence rates, particularly in communal settings.
  • Diagnosis is primarily clinical, based on characteristic morphology and thrombosed capillaries ("black dots"), with biopsy reserved for atypical or resistant cases.
  • The treatment landscape is dominated by topical keratolytics (salicylic acid) and cryotherapy, which remain first-line therapies due to accessibility and established efficacy. Destructive modalities (electrosurgery, laser therapy, surgical excision) are used in refractory cases, but are limited by pain, scarring, and higher costs. Immunotherapeutic approaches (e.g., intralesional Candida antigen) are gaining traction by targeting the underlying viral etiology and reducing recurrence rates.
  • Common warts currently lack FDA-approved, specifically indicated prescription therapies, reflecting a notable treatment gap in dermatology. Available management is largely limited to non-specific approaches such as keratolytic agents (e.g., salicylic acid) and procedural interventions like cryotherapy, rather than targeted, virus-specific drugs. This underscores an unmet need for standardized, evidence-driven pharmacologic options that directly address the underlying HPV infection and improve long-term clearance rates and recurrence control.
  • The emerging pipeline, including CANDIN, YCANTH (VP-102), and KNP2002, focuses on immunomodulatory and antiviral mechanisms to improve efficacy, tolerability, and convenience.
  • The market is characterized by high-volume, low-cost therapies alongside niche, high-value procedures, creating opportunities for innovative, patient-friendly treatments with durable outcomes.

DelveInsight's 'Common Warts - Market Insights, Epidemiology and Market Forecast - 2036' report delivers an in-depth understanding of the common warts, historical and forecasted epidemiology, as well as the common warts market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

The Common Warts market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, common warts patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment, and growth rate projections (Historical & Forecast 2022-2036) across global regions. The report highlights key unmet medical needs in common warts and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.

Key Factors Driving the Common Warts Market

  • Emergence of Targeted and Immunotherapeutic Therapies

The pipeline is shifting toward HPV-targeted and immune-mediated treatments, with assets like CANDIN, YCANTH (VP-102), and KNP2002 aiming to improve efficacy and reduce recurrence, signaling a paradigm shift beyond lesion destruction.

  • High Prevalence and Recurrence Burden

Common warts have high prevalence and recurrence rates, particularly in children and immunocompromised populations, driving repeat treatments and sustained market demand.

  • Demand for Safer and Patient-friendly Treatments

Limitations of current therapies such as pain, scarring, and multiple sessions are increasing demand for minimally invasive, well-tolerated, and convenient options.

Common Warts Understanding and Treatment Algorithm

Common Warts Overview and Diagnosis

Common warts (verruca vulgaris) are benign epidermal proliferations caused by HPV infection, most commonly types 1, 2, 4, 27, and 57, entering through micro-abrasions in the skin. They present as rough, hyperkeratotic papules on the hands, fingers, periungual areas, and feet, often causing pain or cosmetic concern.

They are classified into common, plantar, flat, and periungual warts based on morphology and location. Transmission occurs via direct contact or fomites, making them highly contagious.Despite being benign and self-limiting, they show high recurrence due to persistent HPV infection and immune evasion, and are most prevalent in children, adolescents, and immunocompromised patients, contributing to a high global disease burden.

Common Warts Diagnosis

Diagnosis of common warts (verruca vulgaris) is primarily clinical, based on characteristic appearance of rough, hyperkeratotic papules and typical distribution on the hands, fingers, periungual areas, and feet. A key clinical feature includes thrombosed capillaries ("black dots") on dermoscopic or close examination.

In atypical, recurrent, or treatment-resistant cases, dermoscopy aids visualization of vascular patterns, while skin biopsy may be performed to exclude other lesions and confirm HPV-related pathology. Diagnosis is largely visual and non-invasive, and laboratory testing is rarely required.Accurate and early recognition is important to guide appropriate therapy selection and avoid unnecessary invasive procedures.

Common Warts Diagnosis Treatment

The treatment of common warts (verruca vulgaris) is primarily aimed at lesion removal and reducing recurrence. First-line therapies include topical salicylic acid and cryotherapy (liquid nitrogen), which are widely used due to accessibility and established efficacy, though multiple treatment sessions are often required.

In refractory cases, in-office procedures such as trichloroacetic acid (TCA), electrosurgery, laser therapy, and surgical excision are used to achieve lesion clearance. Immunotherapeutic approaches, including intralesional Candida antigen and other off-label agents, are increasingly used to stimulate a host immune response against HPV, particularly in recurrent or multiple warts. Emerging therapies aim to improve outcomes by targeting the underlying viral infection, including CANDIN (Nielsen BioSciences / Maruho), YCANTH (VP-102) (Verrica Pharmaceuticals / Torii Pharmaceutical), and KNP2002 (KinoPharma / Iwaki Seiyaku), which focus on immunomodulatory and antiviral mechanisms.

Common Warts Unmet Needs

The section "unmet needs of Common warts" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.

1. High recurrence due to persistent HPV infection

2. Lack of HPV-targeted disease-modifying therapies

3. Painful and poorly tolerated procedures in children

4. Poor patient adherence due to long treatment duration

5. No standardized global treatment algorithm for common warts, and others.....

Common Warts Epidemiology

Key Findings from Common Warts Epidemiological Analysis and Forecast

  • According to DelveInsight's estimates, in 2025, the total number of prevalent cases of common warts in the 7MM were ~15,063,000.
  • The highest burden is observed in children and adolescents, while immunocompromised individuals also show significantly increased incidence and persistence rates.
  • HPV infections causing cutaneous warts are most commonly linked to low-risk types 1, 2, 4, 27, and 57, which account for the majority of common wart cases.
  • In Europe, warts were identified as the most common skin disease, with a prevalence of 41.3%, highlighting their significant burden on dermatological health in the region.
  • Plantar warts account for a significant proportion of cases in clinical settings, as they are more likely to become symptomatic due to pressure and pain on weight-bearing surfaces.
  • Despite being benign, common warts show a high spontaneous resolution rate (within 1-2 years in many cases), but a substantial proportion persist or recur due to immune evasion by HPV.
  • As per the secondary analysis, warts are a common condition worldwide, affecting about 10% of the population, with prevalence rising to 10-20% in school-aged children; they are rare in infancy and early childhood, increase during school years, peak between 12 and 16 years, and are more frequently observed in immunosuppressed individuals and meat handlers.

Common Warts Drug Analysis & Competitive Landscape

The Common Warts drug chapter provides a detailed, market-focused review of the emerging pipeline across Phase II-III clinical trials. It covers the mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, and strategic partnerships for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the Common warts treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the Common warts therapeutics market.

Common Warts Pipeline Analysis

CANDIN: Nielsen Biosciences and Maruho

CANDIN (Candida albicans Skin Test Antigen for Cellular Immunity) is being repurposed as an immunotherapeutic approach for common warts, designed to activate the immune system against HPV-driven lesions. Nielsen BioSciences advanced the program to Phase III trial following encouraging Phase II results in the US, which were peer-reviewed and published in Dermatology & Therapy. Currently, CANDIN is approved in the US only as a diagnostic skin test for cellular hypersensitivity to Candida albicans and is not yet approved in the US or Japan for the treatment of common warts.

VP-102 (YCANTH): Verrica Pharmaceuticals and Torii Pharmaceutical

Verrica Pharmaceuticals' lead candidate, YCANTH (VP-102), is a proprietary drug-device combination featuring a GMP-controlled 0.7% cantharidin formulation delivered via a single-use applicator for precise topical dosing. In June 2019, Verrica announced positive topline results from the COVE-1 Phase II open-label trial, which evaluated the safety and efficacy of YCANTH in subjects with up to six common warts. Building on these findings, a Type C meeting with the FDA in November 2023 resulted in alignment on the pivotal Phase III trial design.

Common Warts Key Players, Market Leaders and Emerging Companies

  • Nielsen Biosciences
  • Maruho
  • Verrica Pharmaceuticals
  • Torii Pharmaceutical
  • KinoPharma
  • Iwaki Seiyaku, and others

Common Warts Drug Updates

  • In October 2025, Nielsen BioSciences announced Maruho has expanded its existing licensing agreement with Nielsen BioSciences for CANDIN (Purified Candida albicans Antigen) for the treatment of common warts (verruca vulgaris) in adolescents and adults. Under the expanded agreement, Maruho has secured exclusive development and commercialization rights across additional Asian territories, strengthening its dermatology portfolio and supporting broader regional expansion of this investigational immunotherapy.
  • In January 2026, Verrica Pharmaceuticals announced that the first patient was dosed in December 2025 in the global Phase III program evaluating YCANTH (VP-102) for the treatment of common warts.
  • In December 2025, Verrica Pharmaceuticals announced that the first patient was dosed in the global Phase III program of VP-102 for the treatment of common warts.
  • In August 2025, Iwaki Seiyaku announced that hat it has obtained the results of the safety and efficacy of a Phase II clinical study of an ointment formulation for the indication of verruca vulgaris (also known as "common warts" ) being developed in collaboration with KinoPharma.
  • In July 2025, Verrica Pharmaceuticals announced that it had entered into the second amendment to its existing Collaboration and Licensing Agreement with Torii Pharmaceutical to initiate a global pivotal Phase III clinical trial of Verrica's product, YCANTH, for the treatment of common warts.

Drug Class Insights

Common Warts Market Outlook

The common warts market is evolving gradually from a procedure-driven, lesion-destructive treatment paradigm toward immune-mediated and mechanism-based therapies targeting the underlying HPV infection. While topical salicylic acid and cryotherapy continue to dominate as first-line and in-office standards of care due to their accessibility and familiarity, their limitations in terms of pain, recurrence, and treatment adherence are driving demand for more effective and patient-friendly alternatives. This has created a strong foundation for the development of immunotherapeutic and antiviral approaches aimed at improving long-term clearance rates.

The emergence of novel pipeline assets such as CANDIN (Nielsen BioSciences and Maruho), YCANTH (VP-102) (Verrica Pharmaceuticals and Torii Pharmaceutical), and KNP2002 (KinoPharma and Iwaki Seiyaku) reflects a shift toward immunomodulatory, antiviral, and targeted mechanisms, which are expected to redefine treatment approaches by reducing recurrence and treatment burden.

Geographically, the United States represents the largest market, driven by high treatment uptake, strong dermatology infrastructure, and early adoption of advanced therapies, while EU5 and Japan continue to show steady growth supported by improving access to dermatological care and increasing awareness of treatment options.

Overall, the market is expected to expand steadily during the forecast period, supported by high disease prevalence, persistent recurrence burden, and unmet need for durable therapies, with innovation focused on improved tolerability, convenience, and HPV-targeted mechanisms expected to drive future growth.

Drug Class/Insights into Leading Emerging and Marketed Therapies in Common Warts (2022-2036 Forecast)

The common warts (verruca vulgaris) treatment landscape (2022-2036) is primarily driven by destructive therapies, topical agents, and emerging immunomodulatory and antiviral approaches, with a growing shift toward strategies that enhance lesion clearance, reduce recurrence, and improve patient tolerability rather than relying solely on symptomatic lesion removal.

  • Topical therapies: Include keratolytic agents such as Salicylic acid, which remain the first-line treatment due to strong clinical evidence, OTC availability, and affordability. They act by gradual desquamation of hyperkeratotic tissue, enabling clearance of Human papillomavirus-infected cells. Other topical options include Imiquimod, an immune response modifier used off-label in cutaneous warts to stimulate local antiviral immunity.
  • Non-pharmacological therapies: Include cryotherapy (liquid nitrogen), electrosurgery, curettage, laser ablation, and occlusion-based approaches such as duct tape therapy. These methods are widely used for rapid lesion destruction, particularly in symptomatic or recalcitrant cases, although they may be associated with discomfort and variable recurrence rates.
  • Immunotherapeutic approaches: Include intralesional antigen-based therapies such as CANDIN (Candida antigen), which stimulate a systemic cell-mediated immune response against HPV-infected keratinocytes. These therapies are increasingly utilized in patients with multiple, recurrent, or treatment-resistant warts, offering the advantage of clearing both treated and distant lesions.
  • Emerging and pipeline therapies: The development landscape is evolving with candidates targeting improved efficacy, tolerability, and recurrence prevention. Key assets include VP-102 (a standardized topical cantharidin formulation), CANDIN (being further evaluated for broader dermatologic use), and early-stage programs such as VBP-245 and KNP2002. These therapies leverage vesicant, immunomodulatory, or antiviral mechanisms to provide more consistent and controlled treatment outcomes compared to traditional approaches.

Overall, the current treatment paradigm for common warts is largely centered on topical keratolytics and destructive procedures, which focus on lesion removal rather than viral eradication. However, immunotherapeutic strategies and standardized pipeline agents are expected to shift the landscape toward more targeted, durable, and recurrence-reducing therapies.

Common Warts Drug Uptake

This section focuses on the uptake rate of potential drugs expected to be launched in the market during the forecast period (2026-2036). The analysis covers the common warts drug's uptake, performance at peak, factors affecting performance during prime years of growth, patient uptake by therapy, and anticipated sales generated by each drug.

The uptake of therapies for common warts (verruca vulgaris) is expected to vary across topical agents, procedural interventions, immunotherapies, and emerging targeted therapies, reflecting differences in efficacy, convenience, tolerability, and recurrence outcomes.

Established first-line therapies such as topical salicylic acid are expected to maintain high and sustained uptake due to their over-the-counter availability, low cost, and ease of use, despite requiring prolonged treatment duration. Similarly, cryotherapy is anticipated to retain strong adoption in clinical practice owing to its familiarity among physicians and relatively high clearance rates, particularly in dermatology and primary care settings.

In contrast, off-label immunotherapies such as intralesional Candida antigen (CANDIN-based therapy) are expected to show moderate but increasing uptake, driven by their ability to address immune-mediated clearance and reduce recurrence, especially in refractory and multiple-wart cases.

Next-generation and pipeline therapies such as CANDIN, YCANTH (VP-102), and KNP2002 are expected to demonstrate gradual uptake, supported by growing clinical evidence and a shift toward immunomodulatory and antiviral mechanisms aimed at improving long-term clearance and reducing recurrence burden.

Detailed insights of emerging therapies' drug uptake is included in the report.

Market Access and Reimbursement of Common Warts

Reimbursement may be referred to as the negotiation of a price between a manufacturer and a payer that allows the manufacturer access to the market. It is provided to reduce the high costs and make the essential drugs affordable. Health technology assessment (HTA) plays an important role in reimbursement decision-making and recommending the use of a drug. These recommendations vary widely throughout the seven major markets, even for the same drug. In the US healthcare system, both Public and Private health insurance coverage are included. Also, Medicare and Medicaid are the largest government-funded programs in the US. The major healthcare programs, including Medicare, Medicaid, Health Insurance Program (CHIP), and the state and federal health insurance marketplaces, are overseen by the Centres for Medicare & Medicaid Services (CMS). Other than these, Pharmacy Benefit Managers (PBMs) and third-party organisations that provide services and educational programs to aid patients are also present.

The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of currently used therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

NOTE: Further Details are provided in the final report....

Common Warts Therapies Price Scenario & Trends

Pricing and analogue assessment of common warts therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.

Further details are provided in the final report....

Industry Experts and Physician Views for Common Warts

To keep up with common warts market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry experts were contacted for insights on the common warts emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns in common warts, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.

DelveInsight's analysts connected with 10+ KOLs to gather insights at country level. Centers such as the Baylor Scott and White Research Institute in Dallas, Women's Hospital and Harvard Medical School, and Uppsala University, etc. were contacted.Their opinion helps understand and validate current and emerging common warts therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for market access, therapy adoption, and pipeline prioritization in common warts.

Qualitative Analysis: SWOT and Conjoint Analysis

We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and conjoint analysis.

In the SWOT analysis of Common Warts, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided.

Conjoint analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.

The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.

Scope of the Report:

  • The report covers a segment of key events, an executive summary, a descriptive overview of common warts, explaining their causes, signs and symptoms, pathogenesis, and currently available treatments.
  • Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression along treatment guidelines.
  • Additionally, an all-inclusive account of both the current and emerging treatments, along with the elaborative profiles of late-stage and prominent therapies, will have an impact on the current treatment landscape.
  • A detailed review of the common warts market, historical and forecasted market size, market share by therapies, detailed assumptions, and rationale behind our approach is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies by understanding trends through SWOT analysis and expert insights/KOL views, patient journey, and treatment preferences that help in shaping and driving the 7MM common warts market.

Report Insights

  • Common Warts Patient Population Forecast
  • Common Warts Therapeutics Market Size
  • Common Warts Pipeline Analysis
  • Common Warts Market Size and Trends
  • Common Warts Market Opportunity (Current and forecasted)

Report Key Strengths

  • Epidemiology-based (Epi-based) Bottom-up Forecasting
  • Artificial Intelligence (AI)-Enabled Market Research Report
  • 11-Year Forecast
  • Common Warts Market Outlook (North America, Europe, Asia-Pacific)
  • Patient Burden Trends (By Geography)
  • Common Warts Treatment Addressable Market (TAM)
  • Common Warts Competitive Landscape
  • Common Warts Major Companies Insights
  • Common Warts Price Trends and Analogue Assessment
  • Common Warts Therapies Drug Adoption/Uptake
  • Common Warts Therapies Peak Patient Share Analysis

Report Assessment

  • Common Warts Current Treatment Practices
  • Common Warts Unmet Needs
  • Common Warts Clinical Development Analysis
  • Common Warts Emerging Drugs Product Profiles
  • Common Warts Market attractiveness
  • Common Warts Qualitative Analysis (SWOT and conjoint analysis)

FAQs:

Market Insights

  • What was the common warts market size, the market size by therapies, market share (%) distribution in 2025, and what would it look like by 2036? What are the contributing factors for this growth?
  • What are the anticipated pricing variations among different geographies for the emerging therapies in the future?
  • What can be the future treatment paradigm of common warts?
  • What are the disease risks, burdens, and unmet needs of common warts? What will be the growth opportunities across the 7MM concerning the patient population with common warts?
  • Who is the major future competitor in the market, and how will the competitors affect their market share?
  • What are the current options for the treatment of common warts? What are the current guidelines for treating common warts in the US, Europe, and Japan?

Reasons to Buy:

  • The report will help in developing business strategies by understanding the latest trends and changing treatment dynamics driving the common warts market.
  • Bottom up forecasting builds from the affected population to product forecasts, delivering a robust, data driven approach ideal for new therapies and novel classes.
  • Insights on patient burden/disease incidence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • Understand the existing market opportunities in varying geographies and the growth potential over the coming years.
  • Identifying strong upcoming players in the market will help devise strategies to help get ahead of competitors.
  • Detailed analysis and ranking of class-wise potential emerging therapies under the conjoint analysis section to provide visibility around leading classes.
  • To understand KOLs' perspectives on the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
  • Detailed insights on the unmet needs of the existing market so that the upcoming players can strengthen their development and launch strategy.
  • This Artificial Intelligence (AI) enabled report summarize and simplify complex datasets with in the report into clear, actionable insights for stakeholders, investors, and healthcare providers, enabling faster, data driven decisions.

Table of Contents

1. Key Insights

2. Report Introduction

3. Executive Summary of Common Warts

4. Key Events

  • 4.1. Upcoming Key Catalysts
  • 4.2. Key Conferences And Meetings
  • 4.3. Key Transactions And Collaborations
  • 4.4. News Flow

5. Epidemiology and Market Methodology of . Common Warts

6. Common Warts Market Overview at a Glance

  • 6.1. Emerging Landscape Analysis (By Molecule Type, Phase, and Route of Administration [ROA])
  • 6.2. Market Share of Common Warts By Therapies (%) in the 7MM in 2025
  • 6.3. Market Share of Common Warts By Therapies (%) in the 7MM in 2036

7. Disease Background And Overview of Common Warts

  • 7.1. Introduction
  • 7.2. Signs and Symptoms
  • 7.3. Diagnosis
    • 7.3.1. Diagnostic Algorithm
    • 7.3.2. Diagnostic Guidelines
  • 7.4. Treatment and Management
  • 7.5. Treatment Algorithm
    • 7.5.1. Treatment and Management Guidelines

8. Epidemiology and Patient Population of Common Warts

  • 8.1. Key Findings
  • 8.2. Assumption and Rationale
  • 8.3. Total Diagnosed Prevalent Cases of Warts in the 7MM
  • 8.4. Total Diagnosed Prevalent Cases of Common Warts in the 7MM
  • 8.5. The United States
    • 8.5.1. Total Prevalent Cases of Warts
    • 8.5.2. Total Diagnosed Prevalent Cases of Warts
    • 8.5.3. Total Diagnosed Prevalent Cases of Common Warts
    • 8.5.4. Treated Cases of Common Warts
  • 8.6. EU4 and the UK
    • 8.6.1. Total Prevalent Cases of Warts
    • 8.6.2. Total Diagnosed Prevalent Cases of Warts
    • 8.6.3. Total Diagnosed Prevalent Cases of Common Warts
    • 8.6.4. Treated Cases of Common Warts
  • 8.7. Japan
    • 8.7.1. Total Prevalent Cases of Warts
    • 8.7.2. Total Diagnosed Prevalent Cases of Warts
    • 8.7.3. Total Diagnosed Prevalent Cases of Common Warts
    • 8.7.4. Treated Cases of Common Warts

9. Patient Journey of Common Warts

10. Emerging Therapies

  • 10.1. Competitive Landscape: Emerging Therapies
  • 10.2. CANDIN: Nielsen Biosciences and Maruho
    • 10.2.1. Product Description
    • 10.2.2. Other Developmental Activities
    • 10.2.3. Clinical Development
    • 10.2.4. Safety and Efficacy
    • 10.2.5. Analyst's View
  • 10.3. KNP2002: KinoPharma and Iwaki Seiyaku
    • 10.3.1. Product Description
    • 10.3.2. Other Developmental Activities
    • 10.3.3. Clinical Development
    • 10.3.4. Safety and Efficacy
    • 10.3.5. Analyst's View

Continued emerging therapies will be provided in the final report.

11. Common Warts: Seven Major Market Analysis

  • 11.1. Key Findings
  • 11.2. Market Outlook of Common Warts
  • 11.3. Conjoint Analysis of Common Warts
  • 11.4. Key Market Forecast Assumptions of Common Warts
  • 11.5. Total Market Size of Common Warts in the 7MM
  • 11.6. United States Market Size
    • 11.6.1. Total Market Size of Common Warts in the United States
    • 11.6.2. Market Size of Common Warts by Therapies in United States
  • 11.7. EU4 and the UK Market Size
    • 11.7.1. Total Market Size of Common Warts in EU4 and the UK
    • 11.7.2. Market Size of Common Warts by Therapies in EU4 and the UK
  • 11.8. Japan Market Size
    • 11.8.1. Total Market Size of Common Warts in Japan
    • 11.8.2. Market Size of Common Warts by Therapies in Japan

12. Unmet Needs of Common Warts

13. SWOT Analysis of Common Warts

14. KOL Views of Common Warts

  • 14.1. Expert/KOL Interview Highlights

15. Market Access and Reimbursement of Common Warts

  • 16.1. United States
    • 16.1.1. Centre for Medicare and Medicaid Services (CMS)
  • 16.2. EU4 and the UK
    • 16.2.1. Germany
    • 16.2.2. France
    • 16.2.3. Italy
    • 16.2.4. Spain
    • 16.2.5. United Kingdom
  • 16.3. Japan
  • 16.4. Summary and comparison of Market Access and Pricing Policy Developments in 2025

17. Appendix

  • 17.1. Bibliography
  • 17.2. Report Methodology

18. DelveInsight Capabilities

19. Disclaimer

20. About DelveInsight

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