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시장보고서
상품코드
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차세대 시퀀싱 시장 : 시장 인사이트, 경쟁 구도 및 시장 예측(2034년)Next Generation Sequencing - Market Insights, Competitive Landscape, and Market Forecast - 2034 |
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DelveInsight
차세대 시퀀싱 시장 요약
차세대 시퀀싱(NGS)은 고처리량 염기서열 분석 또는 초병렬 염기서열 분석이라고도 불리며, 수백만 개의 DNA 또는 RNA 단편을 병렬로 읽어서 수년이 아닌 몇 시간 만에 전체 유전체, 전체 엑솜 또는 표적 염기서열 데이터를 생성하는 일련의 기술을 의미합니다. 이 범주에는 합성 기반 시퀀싱 및 반도체 시퀀싱에 기반한 쇼트 리드 플랫폼은 물론, 롱 리드 단일 분자 시퀀싱 및 나노포어 시스템이 포함되며, 이 모든 것은 라이브러리 조제용 소모품, 장비, 바이오인포매틱스 소프트웨어, 외부 위탁 시퀀싱 서비스로 구성된 워크플로우에 의해 뒷받침됩니다. 지난 10년 동안 NGS는 연구용 장비에서 종양학, 생식 의학, 희귀질환 진단, 감염병 감시, 약리유전체학 등 광범위한 분야에서 활용되는 임상 인프라로 전환되었습니다.
차세대 시퀀싱 시장의 주요 성장 동인
차세대 시퀀싱 시장의 성장에 기여하는 요인
시장 성장 촉진요인
시퀀싱 비용의 급격한 하락이 보급을 뒷받침
인간 유전체 시퀀싱 비용은 2001년 약 9,500만 달러에서 2022년에는 5억 2,500만 달러로 극적으로 하락했으며, 주요 고처리량 센터에서는 2023년에 '200달러 유전체' 를 실현하는 데 성공했습니다. 이러한 대폭적인 비용 절감으로 인해 NGS는 연구 중심의 기술에서 비용 대비 효과가 높은 임상 및 공중보건 도구로 변모했으며, 종양학, 희귀질환 진단, 생식 의학 및 대규모 선별 검사 프로그램에서 보다 광범위한 도입이 가능해졌습니다.
세계 암 부담 증가가 유전체 프로파일링 수요 가속화
암 발병률 증가는 계속해서 NGS 도입의 주요 촉진요인으로 작용하고 있습니다. 국제암연구소(IARC)에 따르면, 2022년에는 약 2,000만 건의 신규 암 사례가 진단되었으며, 2050년까지 그 수는 3,500만 건에 달할 것으로 예측됩니다. 정밀 종양학 및 표적 치료가 표준 치료법으로 자리 잡음에 따라, 치료법 선택에는 종합적인 유전체 프로파일링과 동반 진단이 점점 더 필요해지고 있으며, 이는 NGS 기반 검사 및 관련 소모품 수요를 견인하고 있습니다.
시장 제약 요인
성장세가 강함에도 불구하고, 차세대 시퀀싱(NGS) 시장은 중대한 제약에 직면해 있습니다. NGS 기반 체외진단기기(IVD)는 끊임없이 변화하는 미국 식품의약국(FDA), 유럽의 IVDR 및 각국의 임상 검사 프레임워크를 준수해야 하기 때문에 규제 복잡성은 여전히 크며, 이로 인해 신규 분석법 시장 출시 기간이 길어지고 있습니다. 장비의 고가 자본 비용과 소모품비가 지출의 대부분을 차지하는 상황으로 인해, 실제 유전체당 비용은 공시된 수치를 상회하고 있어 소규모 검사실의 도입을 제한하고 있습니다. 또한, 소수의 시약 및 플로우셀 공급업체에 대한 의존을 포함한 제조 및 공급망의 제약으로 인해 검사실은 공급 위험에 노출되어 있습니다. 보험 환급은 지역이나 적응증에 따라 여전히 차이가 있으며, 종양학이나 산전 검사에서는 보험 적용이 확립되어 있지만, 더 광범위한 용도에서는 일관성이 없습니다. 마지막으로, 숙련된 바이오정보학자 부족과 데이터 저장, 해석, 임상 보고에 따른 부담(‘1,000달러짜리 유전체’ 뒤에는 ‘10만 달러짜리 분석’이 있다고도 일컬어집니다)이 처리 능력을 제약하여, 자원이 제한된 환경에서의 도입을 지연시키고 있습니다.
경쟁 현황
차세대 시퀀싱 시장 보고서 조사에서 도출된 주요 포인트
본 차세대 시퀀싱 시장 보고서 조사에서 혜택을 받을 수 있는 대상 독자
Q1. 차세대 시퀀싱 시장의 성장률은 어느 정도입니까?
차세대 시퀀싱 시장은 2026-2034년 예측 기간 동안 연평균 성장률(CAGR) 13.9%로 확대될 것으로 전망됩니다.
Q2. 차세대 시퀀싱 시장 규모는 어느 정도입니까?
차세대 시퀀싱 시장 규모는 2025년에 132억 4,000만 달러로 평가되었으며, 2034년까지 426억 8,000만 달러에 달할 것으로 예측됩니다.
Q3. 차세대 시퀀싱 시장을 주도하는 지역은 어디인가?
북미는 시퀀싱 제조업체 및 임상 검사 기관이 밀집된 기반, NGS 기반 진단을 위한 FDA 승인 절차, 종합적인 유전체 프로파일링에 대한 CMS의 보험 적용을 포함한 넉넉한 보험 환급, 그리고 지속적인 연방 정부의 유전체 연구 자금 지원에 힘입어 2025년에는 세계 매출의 42%를 차지하며 차세대 시퀀싱 시장을 주도했습니다. 아시아태평양은 예측 기간 동안 가장 빠르게 성장할 지역입니다.
Q4. 차세대 시퀀싱 시장의 주요 촉진요인은 무엇인가?
주요 촉진요인은 시퀀싱 비용의 급격한 하락입니다. 미국 국립인간유전체연구소(NHGRI)에 따르면, 인간 유전체 1개당 비용은 2001년 9,500만 달러에서 2022년 525달러로 하락했으며, 2023년에는 200달러대까지 떨어졌습니다. 국제암연구소(IARC)의 예측에 따르면, 세계 암 환자 수는 2022년 신규 사례 2,000만 건에서 2050년까지 3,500만 건으로 증가할 것으로 전망됩니다. 또한, 롱 리드 시퀀싱 및 AI를 활용한 바이오인포매틱스 기술이 성숙해지고, 임상 분야에서의 보험 적용 범위 확대도 이를 뒷받침하고 있습니다.
Q5. 차세대 시퀀싱 시장의 주요 기업은?
주요 기업으로는 일루미나(Illumina), 서모피셔 사이언티픽(Thermo Fisher Scientific), F. 호프만 라 로슈(F. Hoffmann-La Roche), QIAGEN N.V., Pacific Biosciences of California, Inc., Oxford Nanopore Technologies plc, BGI Genomics Co., Ltd., Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Revvity, Inc. 등이 있습니다. 기타에도 ‘경쟁 현황’ 섹션에서 소개된, 활발히 활동 중인 제조업체 및 서비스 제공업체도 포함됩니다.
Next Generation Sequencing Market Summary
Next Generation Sequencing (NGS), also known as high-throughput or massively parallel sequencing, refers to a family of technologies that read millions of DNA or RNA fragments in parallel, producing whole-genome, whole-exome, or targeted sequence data in hours rather than years. The category spans short-read platforms based on sequencing by synthesis and semiconductor sequencing, alongside long-read single-molecule and nanopore systems, all supported by a workflow of library preparation consumables, instruments, bioinformatics software, and outsourced sequencing services. Over the past decade, NGS has moved from a research instrument into a clinical infrastructure used across oncology, reproductive health, rare disease diagnosis, infectious disease surveillance, and pharmacogenomics.
Next Generation Sequencing Market Key Growth Drivers
Key Companies in Next Generation Sequencing Market
The competitive landscape is led by the following active manufacturers and service providers:
Factors Contributing to the Growth of the Next-Generation Sequencing Market
Market Drivers
Rapid Decline in Sequencing Costs Driving Widespread Adoption
The cost of sequencing a human genome has fallen dramatically from approximately USD 95 million in 2001 to USD 525 million in 2022, with leading high-throughput centers achieving the USD 200 genome in 2023. This significant reduction has transformed NGS from a research-focused technology into a cost-effective clinical and population health tool, enabling broader adoption across oncology, rare disease diagnostics, reproductive health, and large-scale screening programs.
Increasing Global Cancer Burden Accelerating Demand for Genomic Profiling
The growing incidence of cancer continues to be a major catalyst for NGS adoption. According to the International Agency for Research on Cancer (IARC), approximately 20 million new cancer cases were diagnosed in 2022, with cases projected to reach 35 million by 2050. As precision oncology and targeted therapies become standard of care, comprehensive genomic profiling and companion diagnostics are increasingly required for treatment selection, driving demand for NGS-based testing and related consumables.
Market Restraints
Despite strong momentum, the Next Generation Sequencing market faces material constraints. Regulatory complexity remains significant, as NGS-based in vitro diagnostics must navigate evolving FDA, European IVDR, and national clinical-laboratory frameworks, lengthening time to market for new assays. High capital costs for instruments and the dominance of consumables expenditure keep the true per-genome cost above headline figures, limiting adoption among smaller laboratories. Manufacturing and supply-chain limitations, including reliance on a concentrated set of reagent and flow-cell suppliers, expose laboratories to availability risk. Reimbursement remains uneven across geographies and indications, with coverage well established for oncology and prenatal testing but inconsistent for broader applications. Finally, a shortage of skilled bioinformaticians and the burden of data storage, interpretation, and clinical reporting, sometimes described as the USD 100,000 analysis behind the USD 1,000 genome, constrain throughput and slow adoption in resource-limited settings.
Next Generation Sequencing Market Segment Analysis
The Next Generation Sequencing Market by Offering (Consumables, Instruments and Platforms, Services), Technology (Sequencing by Synthesis, Ion Semiconductor Sequencing, Single-Molecule Real-Time Sequencing, Nanopore Sequencing, Others), Application (Oncology, Reproductive Health, Clinical Investigation and Diagnostics, Drug Discovery and Personalized Medicine, Agrigenomics and Forensics, Consumer Genomics, Others), End-Users (Academic and Research Institutes, Hospitals and Clinics, Pharmaceutical and Biotechnology Companies, Clinical and Diagnostic Laboratories, Others), and Geography (North America, Europe, Asia-Pacific, Rest of World).
By Offering
Dominant Subsegment: Consumables. The consumables category is expected to dominate the market.
The consumables segment accounted for 51% of the Next Generation Sequencing market in 2025. Consumables, comprising library preparation kits, reagents, flow cells, barcodes, and target enrichment panels, are consumed on every sequencing run, producing recurring revenue that scales directly with testing volume. The structural decline in sequencing cost has expanded run volumes across oncology, reproductive health, and infectious disease testing, deepening consumables demand. Manufacturers reinforce this dynamic through bundled contracts that pair instruments with proprietary reagents, locking laboratories into recurring purchases. Recent launches illustrate continued innovation in this tier: QIAGEN introduced its QIAseq xHYB Long Read Panels in July 2025 to extend target enrichment to long-read platforms, and Illumina launched Illumina Protein Prep in September 2025 to bring proteomics into the sequencing consumables portfolio. The combination of recurring economics, expanding clinical volumes, and a steady cadence of new kit chemistries supports the segment's continued leadership across the forecast period, while the instruments and platforms tier underpins the installed base, and the services tier captures outsourced demand from laboratories that prefer not to run sequencing in-house.
By Technology
Dominant Subsegment: Sequencing by Synthesis. The sequencing by synthesis category is expected to dominate the market.
The sequencing by synthesis segment accounted for 62% of the Next Generation Sequencing market in 2025. Sequencing by synthesis is the most widely deployed NGS chemistry, valued for its high accuracy, scalability, and the lowest cost per gigabase among current platforms, which has made it the default choice for high-throughput clinical and research laboratories. Its dominance is reinforced by the breadth of validated assays, established bioinformatics pipelines, and a large global installed base of short-read instruments. Continued platform innovation sustains the segment, including ongoing throughput and cost improvements across high-capacity systems and the pursuit of the sub-USD 200 genome. Adjacent technologies are advancing rapidly: long-read single-molecule real-time and nanopore platforms are gaining share in structural variant detection and de novo assembly, and Roche introduced its sequencing-by-expansion chemistry in February 2025 as a new high-throughput approach. While these alternatives expand the technology landscape and grow quickly from smaller bases, sequencing by synthesis retains leadership through its accuracy, cost efficiency, and entrenched clinical validation across the forecast period.
By End-User
Dominant Subsegment: Academic and Research Institutes. The academic and research institutes category is expected to dominate the market.
The academic and research institutes segment accounted for 36% of the Next Generation Sequencing market in 2025. Academic and research institutes remain the largest end user because they conduct the foundational genomics, oncology, and population-scale studies that consume large volumes of sequencing capacity and consumables. National genomics programs and university medical centers operate high-throughput core facilities and sustain demand through grant-funded research, supported by ongoing public investment from agencies such as the National Institutes of Health and the National Human Genome Research Institute. These institutions are early adopters of new platforms and chemistries, driving instrument placements and consumables uptake. At the same time, the migration of NGS into routine care is enlarging the hospitals and clinics and clinical and diagnostic laboratories segments, which are growing quickly as comprehensive genomic profiling, prenatal screening, and infectious disease testing move into reimbursed clinical pathways. Pharmaceutical and biotechnology companies also contribute substantial demand through biomarker discovery and companion diagnostic development. While the clinical end users are the fastest-expanding cohort over the forecast period, academic and research institutes retain leadership in 2025 on the strength of research volume and public funding.
Next Generation Sequencing Market Region Analysis
Dominant Region: North America
North America accounted for 42% of the global Next Generation Sequencing market revenue in 2025, representing the highest regional market share globally. The region's dominance reflects the concentration of sequencing manufacturers, academic medical centers, and clinical laboratories in the United States, together with the most developed reimbursement environment for genomic testing. Market-size influence is amplified by high per-capita testing volumes in oncology and reproductive health and by early adoption of long-read sequencing. Healthcare infrastructure is mature, with comprehensive cancer centers and accredited molecular laboratories supporting routine genomic profiling. The regulatory environment is supportive: the FDA provides established pathways for NGS-based in vitro diagnostics, and the Centers for Medicare and Medicaid Services granted reimbursement of USD 2,989.55 per test for TruSight Oncology Comprehensive, effective January 2026. Disease burden is substantial, with about 2 million new cancer cases diagnosed annually in the United States, and the investment landscape is strong, sustained by National Institutes of Health and National Human Genome Research Institute funding alongside private capital concentrated in California and the Northeast.
Fastest Growing Region: Asia-Pacific
Asia-Pacific is the fastest-growing region in the Next Generation Sequencing market. The region's elevated CAGR is driven by rising healthcare investment, expanding genomic research capacity, and growing clinical adoption across China, Japan, India, South Korea, and Australia. Government initiatives, including national genomics and precision-medicine programs, are funding sequencing infrastructure and population-scale projects. Manufacturing expansion is notable, with domestic platform developers scaling production and lowering local costs. Emerging opportunities span agricultural genomics, infectious disease surveillance, and direct-to-consumer testing, supported by a large patient population and increasing collaborations between local and international companies, such as the April 2025 partnership between Gene Solutions and Element Biosciences to deliver cost-effective prenatal and oncology assays across Southeast Asia.
Regional Commentary
North America
North America accounted for 42% of the global Next Generation Sequencing market revenue in 2025. The United States dominates the region on the strength of its manufacturing base, clinical laboratory network, and reimbursement leadership, while Canada contributes through provincial genomics programs and Mexico advances population genomics initiatives such as large-scale national sequencing projects.
Europe
Europe represents the second-largest regional market, led by Germany, the United Kingdom, and France. Growth is supported by national genomics initiatives, public research funding, and the transition to the European In Vitro Diagnostic Regulation, which is raising the bar for clinical NGS assays. Oxford Nanopore's GridION Dx received CE and UKCA markings in early 2026, marking the first IVD-registered nanopore device for the region.
Asia-Pacific
Asia-Pacific is the fastest-growing region, propelled by healthcare investment, expanding research activity, and government precision-medicine programs across China, Japan, India, South Korea, and Australia. Domestic manufacturers are scaling capacity and broadening access to cost-effective sequencing, while agricultural genomics and infectious disease applications add demand beyond clinical diagnostics.
Rest of World
The Rest of World region, spanning the Middle East, Africa, and South America, is an emerging growth frontier. Rising healthcare investment, improving laboratory infrastructure, and international collaborations are expanding access. Illumina renewed its partnership with the Africa Centres for Disease Control and Prevention in March 2025 to equip national laboratories with sequencing tools, strengthening genomic surveillance capacity across the continent.
Next Generation Sequencing Market Competitive Landscape
The Next Generation Sequencing market is classified as Consolidated. A small group of global platform providers controls the majority of instrument and consumables revenue, with Illumina holding the leading position in short-read sequencing platforms, followed by Thermo Fisher Scientific in semiconductor sequencing and a long-read duopoly formed by Oxford Nanopore Technologies and Pacific Biosciences. A broader field of reagents, panels, bioinformatics, and service providers competes in the surrounding value chain.
The competitive landscape can be evaluated across the following dimensions:
Next Generation Sequencing Market Recent Developmental Activities
In January 2026, Illumina, Inc. (with the Centers for Medicare and Medicaid Services), CMS granted national reimbursement for the FDA-approved TruSight Oncology Comprehensive genomic profiling test at USD 2,989.55 per test, effective January 1, 2026. Strategic significance: Establishes durable payer support for large-panel comprehensive genomic profiling, pulling NGS oncology testing into routine reimbursed clinical practice.
In January 2026, Oxford Nanopore Technologies plc Announced that GridION Dx received CE and UKCA markings, the vendor's first in vitro diagnostic device registered in the United Kingdom and Europe, with an initial application in infectious disease characterization through a collaboration with bioMerieux to run the AmPore-TB assay for multidrug-resistant tuberculosis. Strategic significance: Positions nanopore sequencing for regulated clinical diagnostics and validates long-read platforms for infectious disease testing.
In January 2026, Pacific Biosciences of California, Inc., announced plans to collaborate with the nonprofit organizations n-Lorem Foundation and EspeRare to support development of individualized antisense oligonucleotide therapies for ultra-rare genetic disorders. Strategic significance: Extends long-read sequencing into individualized rare-disease therapeutic development, opening a differentiated clinical-research channel.
In January 2026, Daisy Genomics, Inc. (formerly Armonica Technologies) secured USD 2.5 million in seed funding led by Cottonwood Technology Fund and Tramway Venture Partners to advance a spectroscopy-based DNA and RNA sequencing platform toward commercialization. Strategic significance: Signals continued investor appetite for alternative sequencing chemistries that could broaden platform competition.
Next Generation Sequencing Market Segmentation
Next Generation Sequencing Market by Offering
Next Generation Sequencing Market by Technology
Next Generation Sequencing Market by Application
Next Generation Sequencing Market by End-Users
Next Generation Sequencing Market by Geography
Key Takeaways from the Next Generation Sequencing Market Report Study
Target audience who can benefit from this next generation sequencing market report study
Q1. What is the growth rate of the Next Generation Sequencing market?
The Next Generation Sequencing market is projected to expand at a CAGR of 13.9% during the forecast period of 2026-2034.
Q2. What is the market size of the Next Generation Sequencing market?
The Next Generation Sequencing market is estimated at USD 13.24 billion in 2025 and is projected to reach USD 42.68 billion by 2034.
Q3. Which region dominates the Next Generation Sequencing market?
North America dominated the Next Generation Sequencing market with a 42% share of global revenue in 2025, supported by a dense base of sequencing manufacturers and clinical laboratories, FDA pathways for NGS-based diagnostics, strong reimbursement, including CMS coverage of comprehensive genomic profiling, and sustained federal genomics funding. Asia-Pacific is the fastest-growing region over the forecast period.
Q4. What are the key drivers of the Next Generation Sequencing market?
The principal drivers are the collapsing cost of sequencing, with the cost per human genome falling from USD 95 million in 2001 to USD 525 by 2022 and to the USD 200 level in 2023 per the National Human Genome Research Institute; the rising global cancer burden, projected by the International Agency for Research on Cancer to increase from 20 million new cases in 2022 to 35 million by 2050; and the maturation of long-read sequencing and AI-assisted bioinformatics, reinforced by expanding clinical reimbursement.
Q5. Who are the major players in the Next Generation Sequencing market?
The major players include Illumina, Inc., Thermo Fisher Scientific Inc., F. Hoffmann-La Roche Ltd, QIAGEN N.V., Pacific Biosciences of California, Inc., Oxford Nanopore Technologies plc, BGI Genomics Co., Ltd., Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., and Revvity, Inc., among other active manufacturers and service providers profiled in the Competitive Landscape section. Illumina leads short-read platforms, while Oxford Nanopore and Pacific Biosciences anchor the long-read segment.
For illustrative purposes, only the top 10 companies are listed in the Table of Contents. The report may include analysis and references to additional companies where relevant to the market assessment.