미국의 의약품 콜드체인 포장 시장 : 규모, 점유율, 동향 분석 보고서 - 포장 형태별, 기재별, 요구 온도별, 제품별, 컴포넌트별, 용도별 부문 예측(2025-2030년)

U.S. Pharmaceutical Cold Chain Packaging Market Growth & Trends:

The U.S. pharmaceutical cold chain packaging market size is anticipated to reach USD 2.78 billion by 2030 and is projected to grow at a CAGR of 14.6% from 2025 to 2030, according to a new report by Grand View Research, Inc. This is due to the increasing production and distribution of temperature-sensitive drugs, vaccines, and biologics. With advancements in biopharmaceuticals, personalized medicine, and cell & gene therapies, there is a rising need for specialized cold chain solutions that can maintain precise temperature conditions throughout storage and transportation. In addition, the expansion of e-commerce-based drug distribution, stringent regulatory requirements, and a growing focus on sustainability are further driving the market growth for pharmaceutical cold chain packaging and logistics.

The pharmaceutical industry is shifting toward biopharmaceuticals, which include monoclonal antibodies, recombinant proteins, and mRNA vaccines. These biologics require strict temperature control to maintain their potency and efficacy. Most biologics need cold storage (2°C to 8°C), frozen storage (-20°C), or ultra-cold storage (-80°C or lower) during transportation. The rising adoption of these high-value drugs has led to increased investment in cold chain infrastructure, including insulated packaging, real-time monitoring systems, and temperature-controlled storage facilities.

For instance, the success of mRNA-based COVID-19 vaccines highlighted the necessity for ultra-cold chain logistics, prompting companies to expand their cold storage capabilities and invest in innovative packaging solutions. With the continued growth of biologics in treating cancer, autoimmune diseases, and rare disorders, the demand for advanced pharmaceutical cold chain solutions is expected to remain high.

Moreover, the cell & gene therapy market is rapidly expanding, with the U.S. leading in clinical trials and commercial launches. These innovative therapies involve living cells and genetic material, requiring cryogenic storage (-150°C or lower) to preserve viability. CAR-T cell therapies, stem cell treatments, and gene-editing technologies demand specialized cold chain logistics to ensure product integrity from the point of manufacturing to patient administration.

With the rising number of FDA approvals for personalized therapies, there is an urgent need for liquid nitrogen-based cryogenic storage solutions, validated insulated packaging, and precise tracking systems. Cold chain logistics providers are investing in specialized freezers, cryogenic shippers, and smart tracking solutions to support the growing demand for these highly sensitive treatments.

The rise of online pharmacies and direct-to-patient drug delivery is another key factor fueling the demand for pharmaceutical cold chain logistics in the U.S. Many patients, especially those with chronic conditions, now receive medications via mail-order pharmacies and subscription-based drug delivery services. This shift has increased the need for compact, cost-efficient, and insulated packaging solutions that can maintain temperature stability during last-mile distribution.

Leading pharmaceutical companies and logistics providers are expanding cold chain distribution networks to ensure timely and temperature-controlled deliveries. Insulated mailers, refrigerated delivery trucks, and IoT-enabled tracking devices are being widely adopted to support the growing demand for temperature-sensitive drug distribution.

U.S. Pharmaceutical Cold Chain Packaging Market Report Highlights:

• The Expanded Polystyrene (EPS) substrate segment recorded the largest market revenue share of over 15.2% in 2024. Expanded Polystyrene (EPS) substrate is dominating the market due to its superior insulating properties, lightweight structure, cost-effectiveness, and ease of customization.
• The boxes product segment recorded the largest market revenue share of over 51.6% in 2024 due to its superior ability to provide reliable thermal insulation, ease of handling, cost-effectiveness, and widespread use across the pharmaceutical supply chain.
• The insulation component segment recorded the largest market revenue share of over 73.9% in 2024. Insulation materials play a critical role in maintaining the required temperature range for temperature-sensitive pharmaceuticals such as vaccines, biologics, insulin, and specialty drugs during transportation and storage.
• The U.S. pharmaceutical cold chain packaging industry is highly competitive, with key players continuously innovating to meet the growing demand for temperature-sensitive drug transportation.

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Research Methodology
  • 1.1.1. Market Segmentation
  • 1.1.2. Market Definition
• 1.2. Research Scope & Assumptions
• 1.3. Information Procurement
  • 1.3.1. Purchased Database
  • 1.3.2. GVR's Internal Database
  • 1.3.3. Secondary Sources & Third-Party Perspectives
  • 1.3.4. Primary Research
• 1.4. Information Analysis
  • 1.4.1. Data Analysis Models
• 1.5. Market Formulation & Data Visualization
• 1.6. Data Validation & Publishing
• 1.7. List of Abbreviations

Chapter 2. Executive Summary

• 2.1. Market Snapshot, 2024 (USD Million)
• 2.2. Segmental Snapshot
• 2.3. Competitive Landscape Snapshot

Chapter 3. U.S. Pharmaceutical Cold Chain Packaging Market Variables, Trends, and Scope

• 3.1. Market Lineage Outlook
• 3.2. Penetration & Growth Prospect Mapping
• 3.3. Industry Value Chain Analysis
• 3.4. Technology Trends
• 3.5. Regulatory Framework
• 3.6. Market Dynamics
  • 3.6.1. Market Driver Analysis
  • 3.6.2. Market Restraint Analysis
  • 3.6.3. Market Opportunity Analysis
  • 3.6.4. Market Challenge Analysis
• 3.7. Business Environment Analysis
  • 3.7.1. Porter's Five Forces Analysis
  • 3.7.2. PESTEL Analysis

Chapter 4. U.S. Pharmaceutical Cold Chain Packaging Market: Packaging Format Estimates & Trend Analysis

• 4.1. Key Takeaways
• 4.2. Packaging Format Movement Analysis & Market Share, 2024 & 2030
  • 4.2.1. Active
    • 4.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 4.2.2. Passive
    • 4.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 5. U.S. Pharmaceutical Cold Chain Packaging Market: Temperature Requirement Estimates & Trend Analysis

• 5.1. Key Takeaways
• 5.2. Packaging Format Movement Analysis & Market Share, 2024 & 2030
  • 5.2.1. Controlled Room Temperature (15°C - 25°C)
    • 5.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 5.2.2. Refrigerated (2°C - 8°C)
    • 5.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 5.2.3. Frozen (0°C and below)
    • 5.2.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 5.2.4. Deep-Frozen (-20°C to -40°C)
    • 5.2.4.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 5.2.5. Cryogenic (-150°C and below)
    • 5.2.5.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 6. U.S. Pharmaceutical Cold Chain Packaging Market: Substrate Estimates & Trend Analysis

• 6.1. Key Takeaways
• 6.2. Substrate Movement Analysis & Market Share, 2024 & 2030
  • 6.2.1. Polyethylene (PE)
    • 6.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.2. Polypropylene (PP)
    • 6.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.3. Polyethylene Terephthalate (PET)
    • 6.2.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.4. Expanded Polystyrene (EPS)
    • 6.2.4.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.5. Polyurethane (PU)
    • 6.2.5.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.6. Vacuum Insulated Panel (VIP)
    • 6.2.6.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.7. Temperature Insulated Packaging (TIP)
    • 6.2.7.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.8. Metal
    • 6.2.8.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 6.2.9. Others
    • 6.2.9.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 7. U.S. Pharmaceutical Cold Chain Packaging Market: Product Estimates & Trend Analysis

• 7.1. Key Takeaways
• 7.2. Product Movement Analysis & Market Share, 2024 & 2030
  • 7.2.1. Boxes
    • 7.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 7.2.2. Mailers
    • 7.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 7.2.3. Pallets
    • 7.2.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 7.2.4. Others
    • 7.2.4.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 8. U.S. Pharmaceutical Cold Chain Packaging Market: Component Estimates & Trend Analysis

• 8.1. Key Takeaways
• 8.2. Component Movement Analysis & Market Share, 2024 & 2030
  • 8.2.1. Coolant
    • 8.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 8.2.2. Insulation
    • 8.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 9. U.S. Pharmaceutical Cold Chain Packaging Market: Application Estimates & Trend Analysis

• 9.1. Key Takeaways
• 9.2. Application Movement Analysis & Market Share, 2024 & 2030
  • 9.2.1. Biopharmaceutical Companies
    • 9.2.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 9.2.2. Clinical Research Organizations
    • 9.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 9.2.3. Hospitals
    • 9.2.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 9.2.4. Research Institutes
    • 9.2.4.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 9.2.5. Logistics and Distribution Companies
    • 9.2.5.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
  • 9.2.6. Others
    • 9.2.6.1. Market estimates and forecasts, 2018 - 2030 (USD Million)

Chapter 10. Competitive Landscape

• 10.1. Key Global Players & Recent Developments & Their Impact on the Industry
• 10.2. Company/Competition Categorization
• 10.3. Vendor Landscape
  • 10.3.1. List of Raw Material Suppliers
• 10.4. Company Market Position Analysis
• 10.5. Company Heat Map Analysis
• 10.6. Company Dashboard Analysis
• 10.7. Strategy Mapping
  • 10.7.1. Expansions
  • 10.7.2. Mergers & Acquisitions
  • 10.7.3. Collaborations/Partnerships/Agreements
  • 10.7.4. New Product Launches
  • 10.7.5. Others

Chapter 11. Company Listing (Overview, Financial Performance, Products Overview)

• 11.1. Insulated Products Corporation
  • 11.1.1. Company Overview
  • 11.1.2. Financial Performance
  • 11.1.3. Product Benchmarking
• 11.2. Sealed Air
• 11.3. Peli BioThermal Limited
• 11.4. CSafe
• 11.5. Intelsius
• 11.6. Sonoco ThermoSafe
• 11.7. Cryoport Systems, LLC
• 11.8. SkyCell AG
• 11.9. Inmark Global Holdings, LLC
• 11.10. Smurfit Kappa