히알루론산 원료 시장 규모, 점유율, 동향 분석 보고서 : 용도별, 유래별, 등급별, 지역별, 부문별 예측(2026-2033년)

Hyaluronic Acid Raw Material Market Summary

The global hyaluronic acid raw material market size was estimated at USD 245.62 million in 2025 and is projected to reach USD 369.79 million by 2033, growing at a CAGR of 5.25% from 2026 to 2033. This growth is driven by the increasing demand for hyaluronic acid (HA) in medical aesthetics and pharmaceutical & orthopedic applications.

The global hyaluronic acid raw material industry is experiencing significant growth, primarily driven by the increasing demand for aesthetic treatments and dermal fillers. According to a report from the American Society for Aesthetic Plastic Surgery, in March 2024, the number of non-surgical aesthetic procedures has increased, with dermal fillers accounting for a significant share of this growth.

Hyaluronic acid is a key ingredient in these fillers, used for anti-aging, lip enhancement, facial contouring, and wrinkle treatment. This rise is attributed to changing consumer attitudes towards cosmetic procedures and a growing acceptance of such treatments. The increasing number of aesthetic procedures, particularly among younger populations seeking preventive treatments, is contributing to the growing demand for high-quality, injectable-grade hyaluronic acid. Additionally, the increasing disposable income in regions such as the Asia Pacific, particularly in countries like South Korea and China, is further driving demand, as more individuals seek minimally invasive aesthetic treatments.

In parallel, hyaluronic acid is experiencing increased use in medical and therapeutic applications, further contributing to the market's expansion. A study published in the Journal of Orthopedic Research in September 2023 reported that the global market for HA-based viscosupplements for osteoarthritis treatment is growing steadily. Hyaluronic acid is also widely used in ophthalmology for cataract surgeries. According to the American Academy of Ophthalmology Dry Eye Syndrome Preferred Practice Pattern, conservative management of dry eye includes use of artificial tears and ocular lubricants-many of which contain hyaluronic acid/sodium hyaluronate-reflecting HA's widespread role in clinical dry eye therapy.

Additionally, HA-based hydrogels and patches are increasingly used in wound care for chronic wounds, burns, and surgical incisions. According to the World Health Organization article published in September 2025, noncommunicable diseases (NCDs) such as diabetes, cardiovascular diseases, and chronic respiratory conditions continue to impose a major and growing global health burden, accounting for the majority of deaths worldwide. Diabetes prevalence, for example, rose from an estimated 200 million in 1990 to around 830 million in 2022, with the number of affected individuals increasing most rapidly in low and middle income countries, highlighting the increasing clinical demand for related therapeutic and wound care interventions, further driving the need for hyaluronic acid in therapeutic and wound-care applications. This diversification of HA's use across multiple medical disciplines strengthens its position as a key material in the healthcare sector.

The cosmetics and personal care sector also remains a major driver for HA demand, with the ingredient being widely incorporated into skincare products due to its hydrating properties. This growth is driven by increasing consumer interest in skincare products, ranging from serums and creams to masks and hybrid formulations. Interest in oral hyaluronic acid supplementation for skin health has increased in recent years, with clinical research and meta analyses indicating potential benefits for skin hydration and elasticity. Randomized controlled trials have shown that oral HA intake can significantly enhance skin hydration and appearance, supporting its inclusion in anti aging and cosmetic nutraceutical regimens. As e-commerce continues to grow and cross-border beauty trends gain traction, the global demand for HA in both topical and ingestible products is expected to continue, further contributing to the expansion of the HA raw material market.

Global Hyaluronic Acid Raw Material Market Report Segmentation

This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global hyaluronic acid raw material market report based on application, source, grade, and region:

• Application Outlook (Revenue, USD Million, 2021 - 2033)
• Pharmaceutical & Medical Applications
  • Ophthalmology
  • Cataract surgery (as ophthalmic viscoelastic devices - OVDs)
  • Aqueous eye drops (for lubrication and corneal protection)
  • Contact lens hydration
  • Orthopedics
  • Viscosupplements
  • Bone regeneration (as scaffolds and fillers in orthopedic implants)
  • Dermatology (Medical use)
  • Advance Wound Healing (HA-based dressings and gels)
  • Surgical / Medical Uses
  • Surgical adhesion prevention (HA-based anti-adhesive gels and membranes)
  • Medical device coating (for biocompatibility and lubrication)
  • Biomaterials and Implants
  • Cell and Tissue Preservation
• Cosmetic & Aesthetic Applications
  • Dermatology (Aesthetic use)
  • Intradermal (cosmetic injectables)
  • Dermal filler (aesthetic fillers)
  • Cosmetic / Personal Care (Creams, serums, moisturizers, lotions)
• Nutraceutical & Food Supplement Applications
• Other / Emerging Industrial Applications
  • Drug Delivery Systems (HA-based carriers for APIs)
  • Biomaterials (R&D) [Smart hydrogels, nanomaterials]
  • Other
• Source Outlook (Revenue, USD Million, 2021 - 2033)
• Non-Animal
• Animal
• Grade Outlook (Revenue, USD Million, 2021 - 2033)
• Pharmaceutical (API) Grade (Orthopedic & others)
• Cosmetic Grade
• Food Grade
• Other (research-grade HA)
• Regional Outlook (Revenue, USD Million, 2021 - 2033)
• North America
  • U.S.
  • Canada
  • Mexico
• Europe
  • UK
  • Germany
  • France
  • Italy
  • Spain
  • Denmark
  • Sweden
  • Norway
• Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • South Korea
  • Thailand
• Latin America
  • Brazil
  • Argentina
• Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Kuwait

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation & Scope
• 1.2. Segment Definitions
  • 1.2.1. Application
  • 1.2.2. Source
  • 1.2.3. Grade
• 1.3. Estimates and Forecast Timeline
• 1.4. Research Methodology
• 1.5. Information Procurement
  • 1.5.1. Purchased Database
  • 1.5.2. GVR's Internal Database
  • 1.5.3. Secondary Sources
  • 1.5.4. Primary Research
• 1.6. Information Analysis
  • 1.6.1. Data Analysis Models
• 1.7. Market Formulation & Data Visualization
• 1.8. Model Details
  • 1.8.1. Commodity Flow Analysis
• 1.9. List of Secondary Sources
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Snapshot
• 2.2. Segment Snapshot
• 2.3. Competitive Landscape Snapshot

Chapter 3. Hyaluronic Acid Raw Material Market Variables, Trends, & Scope

• 3.1. Market Lineage Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
  • 3.2.2. Market Restraint Analysis
• 3.3. Business Environment Analysis
  • 3.3.1. Industry Analysis - Porter's Five Forces Analysis
    • 3.3.1.1. Supplier Power
    • 3.3.1.2. Buyer Power
    • 3.3.1.3. Substitution Threat
    • 3.3.1.4. Threat of New Entrants
    • 3.3.1.5. Competitive Rivalry
  • 3.3.2. PESTLE Analysis
  • 3.3.3. Pipeline Analysis
  • 3.3.4. Patent Expiry Analysis
  • 3.3.5. Pricing Analysis

Chapter 4. Hyaluronic Acid Raw Material Market: Application Business Analysis

• 4.1. Application Market Share, 2025 & 2033
• 4.2. Application Segment Dashboard
• 4.3. Market Size & Forecasts and Trend Analysis, by Application, 2021 to 2033 (USD Million)
• 4.4. Pharmaceutical & Medical Applications
  • 4.4.1. Pharmaceutical & Medical Applications Market, 2021 - 2033 (USD Million)
  • 4.4.2. Ophthalmology Market, 2021 - 2033 (USD Million)
    • 4.4.2.1. Cataract surgery (as ophthalmic viscoelastic devices - OVDs) Market, 2021 - 2033 (USD Million)
    • 4.4.2.2. Aqueous eye drops (for lubrication and corneal protection) Market, 2021 - 2033 (USD Million)
    • 4.4.2.3. Contact lens hydration Market, 2021 - 2033 (USD Million)
  • 4.4.3. Orthopedics Market, 2021 - 2033 (USD Million)
    • 4.4.3.1. Viscosupplements Market, 2021 - 2033 (USD Million)
    • 4.4.3.2. Bone regeneration (as scaffolds and fillers in orthopedic implants) Market, 2021 - 2033 (USD Million)
  • 4.4.4. Dermatology (Medical use) Market, 2021 - 2033 (USD Million)
    • 4.4.4.1. Advance Wound Healing (HA-based dressings and gels) Market, 2021 - 2033 (USD Million)
  • 4.4.5. Surgical / Medical Uses Market, 2021 - 2033 (USD Million)
    • 4.4.5.1. Surgical adhesion prevention (HA-based anti-adhesive gels and membranes) Market, 2021 - 2033 (USD Million)
    • 4.4.5.2. Medical device coating (for biocompatibility and lubrication) Market, 2021 - 2033 (USD Million)
  • 4.4.6. Biomaterials and Implants Market, 2021 - 2033 (USD Million)
  • 4.4.7. Cell and Tissue Preservation Market, 2021 - 2033 (USD Million)
• 4.5. Cosmetic & Aesthetic Applications
  • 4.5.1. Cosmetic & Aesthetic Applications Market, 2021 - 2033 (USD Million)
  • 4.5.2. Dermatology (Aesthetic use) Market, 2021 - 2033 (USD Million)
    • 4.5.2.1. Intradermal (cosmetic injectables) Market, 2021 - 2033 (USD Million)
    • 4.5.2.2. Dermal filler (aesthetic fillers) Market, 2021 - 2033 (USD Million)
  • 4.5.3. Cosmetic / Personal Care (Creams, serums, moisturizers, lotions) Market, 2021 - 2033 (USD Million)
• 4.6. Nutraceutical & Food Supplement Applications
  • 4.6.1. Nutraceutical & Food Supplement Applications Market, 2021 - 2033 (USD Million)
• 4.7. Other / Emerging Industrial Applications
  • 4.7.1. Other / Emerging Industrial Applications Market, 2021 - 2033 (USD Million)
  • 4.7.2. Drug Delivery Systems (HA-based carriers for APIs) Market, 2021 - 2033 (USD Million)
  • 4.7.3. Biomaterials (R&D) [Smart hydrogels, nanomaterials] Market, 2021 - 2033 (USD Million)
  • 4.7.4. Other Market, 2021 - 2033 (USD Million)

Chapter 5. Hyaluronic Acid Raw Material Market: Source Business Analysis

• 5.1. Source Market Share, 2025 & 2033
• 5.2. Source Segment Dashboard
• 5.3. Market Size & Forecasts and Trend Analysis, by Source, 2021 to 2033 (USD Million)
• 5.4. Non-Animal
  • 5.4.1. Non-Animal Market, 2021 - 2033 (USD Million)
• 5.5. Animal
  • 5.5.1. Animal Market, 2021 - 2033 (USD Million)

Chapter 6. Hyaluronic Acid Raw Material Market: Grade Business Analysis

• 6.1. Grade Market Share, 2025 & 2033
• 6.2. Grade Segment Dashboard
• 6.3. Market Size & Forecasts and Trend Analysis, by Grade, 2021 to 2033 (USD Million)
• 6.4. Pharmaceutical (API) Grade (Orthopedic & others)
  • 6.4.1. Pharmaceutical (API) Grade (Orthopedic & others) Market, 2021 - 2033 (USD Million)
• 6.5. Cosmetic Grade
  • 6.5.1. Cosmetic Grade Market, 2021 - 2033 (USD Million)
• 6.6. Food Grade
  • 6.6.1. Food Grade Market, 2021 - 2033 (USD Million)
• 6.7. Other (research-grade HA)
  • 6.7.1. Other (research-grade HA) Market, 2021 - 2033 (USD Million)

Chapter 7. Hyaluronic Acid Raw Material Market: Regional Estimates & Trend Analysis

• 7.1. Regional Market Share Analysis, 2025 & 2033
• 7.2. Regional Market Dashboard
• 7.3. Market Size & Forecasts Trend Analysis, 2021 to 2033:
• 7.4. North America
  • 7.4.1. North America Hyaluronic Acid Raw Material Market Estimates and Forecasts, By Country, 2021 - 2033 (USD Million)
  • 7.4.2. U.S.
    • 7.4.2.1. Key Country Dynamics
    • 7.4.2.2. Regulatory Framework
    • 7.4.2.3. Pricing Analysis
    • 7.4.2.4. U.S. Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.4.3. Canada
    • 7.4.3.1. Key Country Dynamics
    • 7.4.3.2. Regulatory Framework
    • 7.4.3.3. Pricing Analysis
    • 7.4.3.4. U.S. Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.4.4. Mexico
    • 7.4.4.1. Key Country Dynamics
    • 7.4.4.2. Regulatory Framework
    • 7.4.4.3. Pricing Analysis
    • 7.4.4.4. Mexico Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.5. Europe
  • 7.5.1. Europe Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.2. UK
    • 7.5.2.1. Key Country Dynamics
    • 7.5.2.2. Regulatory Framework
    • 7.5.2.3. Pricing Analysis
    • 7.5.2.4. UK Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.3. Germany
    • 7.5.3.1. Key Country Dynamics
    • 7.5.3.2. Regulatory Framework
    • 7.5.3.3. Pricing Analysis
    • 7.5.3.4. Germany Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.4. France
    • 7.5.4.1. Key Country Dynamics
    • 7.5.4.2. Regulatory Framework
    • 7.5.4.3. Pricing Analysis
    • 7.5.4.4. France Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.5. Italy
    • 7.5.5.1. Key Country Dynamics
    • 7.5.5.2. Regulatory Framework
    • 7.5.5.3. Pricing Analysis
    • 7.5.5.4. Italy Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.6. Spain
    • 7.5.6.1. Key Country Dynamics
    • 7.5.6.2. Regulatory Framework
    • 7.5.6.3. Pricing Analysis
    • 7.5.6.4. Spain Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.7. Denmark
    • 7.5.7.1. Key Country Dynamics
    • 7.5.7.2. Regulatory Framework
    • 7.5.7.3. Pricing Analysis
    • 7.5.7.4. Denmark Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.8. Sweden
    • 7.5.8.1. Key Country Dynamics
    • 7.5.8.2. Regulatory Framework
    • 7.5.8.3. Pricing Analysis
    • 7.5.8.4. Sweden Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.5.9. Norway
    • 7.5.9.1. Key Country Dynamics
    • 7.5.9.2. Regulatory Framework
    • 7.5.9.3. Pricing Analysis
    • 7.5.9.4. Norway Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.6. Asia Pacific
  • 7.6.1. Asia Pacific Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.2. Japan
    • 7.6.2.1. Key Country Dynamics
    • 7.6.2.2. Regulatory Framework
    • 7.6.2.3. Pricing Analysis
    • 7.6.2.4. Japan Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.3. China
    • 7.6.3.1. Key Country Dynamics
    • 7.6.3.2. Regulatory Framework
    • 7.6.3.3. Pricing Analysis
    • 7.6.3.4. China Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.4. India
    • 7.6.4.1. Key Country Dynamics
    • 7.6.4.2. Regulatory Framework
    • 7.6.4.3. Pricing Analysis
    • 7.6.4.4. India Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.5. Australia
    • 7.6.5.1. Key Country Dynamics
    • 7.6.5.2. Regulatory Framework
    • 7.6.5.3. Pricing Analysis
    • 7.6.5.4. Australia Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.6. South Korea
    • 7.6.6.1. Key Country Dynamics
    • 7.6.6.2. Regulatory Framework
    • 7.6.6.3. Pricing Analysis
    • 7.6.6.4. South Korea Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.6.7. Thailand
    • 7.6.7.1. Key Country Dynamics
    • 7.6.7.2. Regulatory Framework
    • 7.6.7.3. Pricing Analysis
    • 7.6.7.4. Thailand Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.7. Latin America
  • 7.7.1. Latin America Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.7.2. Brazil
    • 7.7.2.1. Key Country Dynamics
    • 7.7.2.2. Regulatory Framework
    • 7.7.2.3. Pricing Analysis
    • 7.7.2.4. Brazil Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.7.3. Argentina
    • 7.7.3.1. Key Country Dynamics
    • 7.7.3.2. Regulatory Framework
    • 7.7.3.3. Pricing Analysis
    • 7.7.3.4. Argentina Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.8. Middle East and Africa
  • 7.8.1. Middle East and Africa Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.8.2. South Africa
    • 7.8.2.1. Key Country Dynamics
    • 7.8.2.2. Regulatory Framework
    • 7.8.2.3. Pricing Analysis
    • 7.8.2.4. South Africa Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.8.3. Saudi Arabia
    • 7.8.3.1. Key Country Dynamics
    • 7.8.3.2. Regulatory Framework
    • 7.8.3.3. Pricing Analysis
    • 7.8.3.4. Saudi Arabia Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.8.4. UAE
    • 7.8.4.1. Key Country Dynamics
    • 7.8.4.2. Regulatory Framework
    • 7.8.4.3. Pricing Analysis
    • 7.8.4.4. UAE Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)
  • 7.8.5. Kuwait
    • 7.8.5.1. Key Country Dynamics
    • 7.8.5.2. Regulatory Framework
    • 7.8.5.3. Pricing Analysis
    • 7.8.5.4. Kuwait Hyaluronic Acid Raw Material Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 8. Competitive Landscape

• 8.1. Participant Overview
• 8.2. Company Market Position Analysis
• 8.3. Company Categorization
• 8.4. Strategy Mapping
• 8.5. Company Profiles/Listing
  • 8.5.1. Bloomage Biotech
    • 8.5.1.1. Overview
    • 8.5.1.2. Financial Performance
    • 8.5.1.3. Application Benchmarking
    • 8.5.1.4. Strategic Initiatives
  • 8.5.2. HTL Biotechnology
    • 8.5.2.1. Overview
    • 8.5.2.2. Financial Performance
    • 8.5.2.3. Application Benchmarking
    • 8.5.2.4. Strategic Initiatives
  • 8.5.3. Fidia Farmaceutici S.p.A.
    • 8.5.3.1. Overview
    • 8.5.3.2. Financial Performance
    • 8.5.3.3. Application Benchmarking
    • 8.5.3.4. Strategic Initiatives
  • 8.5.4. Contipro a.s.
    • 8.5.4.1. Overview
    • 8.5.4.2. Financial Performance
    • 8.5.4.3. Application Benchmarking
    • 8.5.4.4. Strategic Initiatives
  • 8.5.5. Seikagaku Corporation
    • 8.5.5.1. Overview
    • 8.5.5.2. Financial Performance
    • 8.5.5.3. Application Benchmarking
    • 8.5.5.4. Strategic Initiatives
  • 8.5.6. Lifecore Biomedical, Inc.
    • 8.5.6.1. Overview
    • 8.5.6.2. Financial Performance
    • 8.5.6.3. Application Benchmarking
    • 8.5.6.4. Strategic Initiatives
  • 8.5.7. Kewpie Corporation
    • 8.5.7.1. Overview
    • 8.5.7.2. Financial Performance
    • 8.5.7.3. Application Benchmarking
    • 8.5.7.4. Strategic Initiatives
  • 8.5.8. Shandong Focuschem Biotech Co., Ltd.
    • 8.5.8.1. Overview
    • 8.5.8.2. Financial Performance
    • 8.5.8.3. Application Benchmarking
    • 8.5.8.4. Strategic Initiatives
  • 8.5.9. Shandong Freda Biopharm Co., Ltd.
    • 8.5.9.1. Overview
    • 8.5.9.2. Financial Performance
    • 8.5.9.3. Application Benchmarking
    • 8.5.9.4. Strategic Initiatives
  • 8.5.10. Shandong Topscience Biotech Co.
    • 8.5.10.1. Overview
    • 8.5.10.2. Financial Performance
    • 8.5.10.3. Application Benchmarking
    • 8.5.10.4. Strategic Initiatives