남성 불임 시장 보고서 : 검사 유형, 치료, 유통 채널, 최종사용자, 지역별(2025-2033년)

The global male infertility market size was valued at USD 4.21 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 6.32 Billion by 2033, exhibiting a CAGR of 4.51% during 2025-2033. Europe currently dominates the market. The rise in the prevalence of male infertility, emerging trend of delayed parenthood, notable technological advancements, changing lifestyles, increasing awareness about infertility, and legalization of assisted reproductive technologies are some of the major factors propelling the market.

Male infertility refers to the condition in which a man is unable to impregnate a female partner due to factors related to his reproductive system. It is often attributed to issues with sperm production, quality, or delivery. Factors that can contribute to male infertility include low sperm count, abnormal sperm shape or motility, hormonal imbalances, genetic factors, and certain medical conditions like varicocele (enlarged veins in the scrotum). Lifestyle factors such as excessive alcohol consumption, smoking, drug use, and obesity can also play a role in male infertility.

The rising incidence of male infertility worldwide is a significant driver for the market. Changing lifestyles, environmental pollutants, and stress-related factors contribute to this growing concern, necessitating the need for diagnostic and treatment solutions. Additionally, the trend of delaying parenthood to pursue career goals and other life aspirations has led to higher age-related fertility issues among men. This has spurred the demand for male infertility treatments and assisted reproductive technologies. Other than this, increasing awareness about fertility issues, thanks to educational campaigns and digital resources, has prompted more men to seek medical assistance for infertility problems, thus driving the market growth. Besides this, sedentary lifestyles, poor dietary habits, and increased exposure to environmental toxins have been linked to declining sperm quality and quantity. As individuals become more conscious of these factors, the demand for interventions and treatments to counteract these effects has risen. In line with this, advancements in medical technologies have improved the accuracy of diagnostic procedures and treatment options for male infertility. Innovative techniques such as sperm DNA fragmentation analysis and advanced sperm selection methods have enhanced treatment outcomes.

Male Infertility Market Trends/Drivers:

Increasing Prevalence of Male Infertility

A multitude of factors, including sedentary lifestyles, exposure to environmental pollutants, and high stress levels, have collectively contributed to a rise in fertility issues among men. These factors can adversely affect sperm production, quality, and motility. As the prevalence of male infertility becomes more recognized, there is a growing demand for accurate diagnostics and effective treatment options. Couples are seeking medical expertise to address these concerns, leading to increased consultations and adoption of fertility services.

Rising Trend of Delayed Parenthood

The trend of delaying parenthood has gained momentum due to evolving societal norms and career aspirations. However, advancing age is associated with a decline in male fertility, including decreased sperm quality and increased DNA fragmentation. This phenomenon has given rise to age-related fertility challenges among men. As a result, the male infertility market is witnessing a surge in demand for fertility preservation and treatment options among older men who wish to start families later in life. This trend emphasizes the need for specialized interventions that cater to the unique requirements of this demographic.

Significant Technological Advancements

Innovative techniques such as sperm DNA fragmentation analysis enable a more comprehensive assessment of sperm quality. Additionally, advanced sperm selection methods, such as magnetic-activated cell sorting (MACS), enhance the chances of successful fertilization. These technologies offer improved accuracy in identifying underlying causes of infertility and provide healthcare professionals with a wider range of tools to tailor treatment plans. As technology continues to evolve, it has the potential to significantly improve outcomes and contribute to the growth of the male infertility market by providing patients with more effective and personalized solutions.

Breakup by Test Type:

• Sperm Agglutination
• DNA Fragmentation Technique
• Oxidative Stress Analysis
• Computer Assisted Semen Analysis
• Sperm Penetration Assay
• Others

DNA fragmentation technique dominates the market

The DNA fragmentation technique stands as the largest segment in the market breakup by test type due to its ability to offer deeper insights into male infertility. This technique assesses DNA damage within sperm, providing crucial information about sperm quality. As a result, it has gained prominence in accurately diagnosing the underlying causes of male infertility, guiding tailored treatment approaches for better outcomes.

Breakup by Treatment:

• Medication
• Assisted Reproductive Technology and Varicocele Surgery

Assisted reproductive technology and varicocele surgery hold the largest market share

ART, encompassing techniques like in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), offers couples the opportunity to overcome various fertility challenges, including male factor infertility. The success rates and advancements in ART have positioned it as a leading choice. Varicocele surgery, on the other hand, is a well-established surgical intervention to treat varicoceles, which are dilated veins in the scrotum that can impede sperm production and quality. By surgically correcting varicoceles, blood flow is improved, potentially enhancing sperm production and motility. This procedure has demonstrated positive outcomes in restoring fertility potential. The popularity of these treatments arises from their proven efficacy, leading to their prominent status in the market's treatment landscape.

Breakup by Distribution Channel:

• Hospitals Pharmacies
• Pharmacies and Drug Stores
• Online Pharmacies

Male infertility products are majorly distributed through hospital pharmacies

Hospitals offer a range of specialized diagnostic facilities, medical expertise, and treatment options under one roof. This makes them a primary destination for patients seeking comprehensive evaluation, consultations with fertility specialists, and advanced interventions, including assisted reproductive technologies (ART) and surgical procedures. Pharmacies play a crucial role by providing access to prescription medications, supplements, and fertility-related products that support male reproductive health. They serve as convenient points of access for patients to obtain prescribed medications for fertility treatment and management. Additionally, pharmacies offer a discreet environment where individuals can access over-the-counter fertility supplements and products that complement treatment plans.

Breakup by End User:

• Hospitals and Clinics
• Fertility Centers
• Research Institutes
• Others

Fertility centers account for the majority of the share in the market

These centers are dedicated to providing a wide range of services specifically tailored to individuals and couples facing fertility challenges. Fertility centers house a team of experienced reproductive endocrinologists, urologists, embryologists, and other specialists who collectively offer advanced diagnostic evaluations, personalized treatment plans, and assisted reproductive technologies (ART) under one roof. The multidisciplinary nature of fertility centers allows for a holistic approach to male infertility, encompassing medical assessments, laboratory analyses, and innovative treatments. These centers offer a supportive environment that addresses the emotional and physical aspects of fertility struggles. The availability of state-of-the-art technologies, cutting-edge procedures, and a comprehensive understanding of male reproductive health positions fertility centers as the preferred choice for individuals seeking expert guidance and successful outcomes in their journey towards overcoming male infertility.

Breakup by Region:

• North America
• United States
• Canada
• Europe
• Germany
• France
• United Kingdom
• Italy
• Spain
• Russia
• Others
• Asia Pacific
• China
• Japan
• India
• South Korea
• Australia
• Indonesia
• Others
• Latin America
• Brazil
• Mexico
• Others
• Middle East and Africa

Europe exhibits a clear dominance in the market

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Europe accounted for the largest market share.

The region possesses a well-developed healthcare infrastructure, including advanced medical facilities, fertility clinics, and research institutions, enabling efficient diagnosis and treatment of male infertility. Moreover, changing socio-cultural dynamics have led to increased awareness and acceptance of fertility issues, prompting more individuals and couples to seek medical intervention. European countries also prioritize reproductive health and offer comprehensive healthcare coverage, making fertility treatments more accessible to a larger population. The aging population across the region contributes to a growing demand for assisted reproductive technologies (ART) as delayed parenthood becomes more common. Furthermore, the strong presence of Europe in medical research and development fuels innovations in male infertility treatments, attracting both domestic and international patients seeking cutting-edge solutions.

Competitive Landscape:

Leading companies are investing significantly in research and development to create new and improved diagnostic tools, treatments, and technologies for male infertility. This includes developing innovative sperm analysis techniques, medications, and assisted reproductive technologies to enhance treatment outcomes. Additionally, key players often collaborate with academic institutions, research organizations, and healthcare providers to exchange knowledge, share insights, and drive advancements in male infertility diagnostics and treatments. These collaborations foster a synergistic approach to tackling complex challenges and developing comprehensive solutions. Other than this, recognizing the importance of raising awareness about male infertility, industry leaders are actively involved in educational initiatives. They offer information through online platforms, seminars, and healthcare professional training, aimed at increasing understanding of the condition and encouraging timely interventions. Moreover, key players engage in strategic expansion efforts to tap into emerging markets with growing demand for male infertility treatments. By extending their reach, they aim to provide access to advanced diagnostics and therapies to a wider patient population.

The market research report has provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the key players in the market include:

• Andrology Solutions
• CinnaGen Co.
• Halotech DNA
• SCSA Diagnostics Inc.
• Vitrolife
• Zydus Lifesciences Limited
• Intas Pharmaceuticals Ltd.
• Endo International plc.

Recent Developments:

Andrology Solutions has made recent advancements in the field of male infertility, including improvements in the understanding and management of male factor infertility. It has also worked on developing panels for male infertility genes, which have achieved high accuracy in diagnosing copy number variants (CNVs). These advancements contribute to the diagnosis and treatment of male infertility, allowing for more effective interventions and improved outcomes.

Halotech DNA, a leading international biotech company based in Madrid, has introduced innovative DNA fragmentation analysis systems for evaluating sperm quality. These systems are designed to assess the level of DNA damage in sperm cells, which can be a contributing factor to male infertility. This analysis helps in identifying the underlying causes of infertility and guides the selection of appropriate treatment options.

In 2022, SCSA Diagnostics Inc. developed a test called the SCSA (Sperm Chromatin Structure Assay), which is used to evaluate sperm chromatin structure and DNA strand breaks. The SCSA test is a two-fold simultaneous flow cytometry measure of the extent of sperm nuclear single (ss) and double (ds) strand DNA breaks. This test provides unique information about male infertility by assessing the integrity of sperm DNA, which is crucial for successful fertilization and embryo development.

Key Questions Answered in This Report

• 1.How big is the male infertility market?
• 2.What is the future outlook of the male infertility market?
• 3.What are the key factors driving the global male infertility market?
• 4.Which region accounts for the largest male infertility market share?
• 5.Which are the leading companies in the global male infertility market?

Table of Contents

1 Preface

2 Scope and Methodology

• 2.1 Objectives of the Study
• 2.2 Stakeholders
• 2.3 Data Sources
  • 2.3.1 Primary Sources
  • 2.3.2 Secondary Sources
• 2.4 Market Estimation
  • 2.4.1 Bottom-Up Approach
  • 2.4.2 Top-Down Approach
• 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

• 4.1 Overview
• 4.2 Key Industry Trends

5 Global Male Infertility Market

• 5.1 Market Overview
• 5.2 Market Performance
• 5.3 Impact of COVID-19
• 5.4 Market Forecast

6 Market Breakup by Test Type

• 6.1 Sperm Agglutination
  • 6.1.1 Market Trends
  • 6.1.2 Market Forecast
• 6.2 DNA Fragmentation Technique
  • 6.2.1 Market Trends
  • 6.2.2 Market Forecast
• 6.3 Oxidative Stress Analysis
  • 6.3.1 Market Trends
  • 6.3.2 Market Forecast
• 6.4 Computer Assisted Semen Analysis
  • 6.4.1 Market Trends
  • 6.4.2 Market Forecast
• 6.5 Sperm Penetration Assay
  • 6.5.1 Market Trends
  • 6.5.2 Market Forecast
• 6.6 Others
  • 6.6.1 Market Trends
  • 6.6.2 Market Forecast

7 Market Breakup by Treatment

• 7.1 Medication
  • 7.1.1 Market Trends
  • 7.1.2 Market Forecast
• 7.2 Assisted Reproductive Technology and Varicocele Surgery
  • 7.2.1 Market Trends
  • 7.2.2 Market Forecast

8 Market Breakup by Distribution Channel

• 8.1 Hospitals Pharmacies
  • 8.1.1 Market Trends
  • 8.1.2 Market Forecast
• 8.2 Pharmacies and Drug Stores
  • 8.2.1 Market Trends
  • 8.2.2 Market Forecast
• 8.3 Online Pharmacies
  • 8.3.1 Market Trends
  • 8.3.2 Market Forecast

9 Market Breakup by End User

• 9.1 Hospitals and Clinics
  • 9.1.1 Market Trends
  • 9.1.2 Market Forecast
• 9.2 Fertility Centers
  • 9.2.1 Market Trends
  • 9.2.2 Market Forecast
• 9.3 Research Institutes
  • 9.3.1 Market Trends
  • 9.3.2 Market Forecast
• 9.4 Others
  • 9.4.1 Market Trends
  • 9.4.2 Market Forecast

10 Market Breakup by Region

• 10.1 North America
  • 10.1.1 United States
    • 10.1.1.1 Market Trends
    • 10.1.1.2 Market Forecast
  • 10.1.2 Canada
    • 10.1.2.1 Market Trends
    • 10.1.2.2 Market Forecast
• 10.2 Asia-Pacific
  • 10.2.1 China
    • 10.2.1.1 Market Trends
    • 10.2.1.2 Market Forecast
  • 10.2.2 Japan
    • 10.2.2.1 Market Trends
    • 10.2.2.2 Market Forecast
  • 10.2.3 India
    • 10.2.3.1 Market Trends
    • 10.2.3.2 Market Forecast
  • 10.2.4 South Korea
    • 10.2.4.1 Market Trends
    • 10.2.4.2 Market Forecast
  • 10.2.5 Australia
    • 10.2.5.1 Market Trends
    • 10.2.5.2 Market Forecast
  • 10.2.6 Indonesia
    • 10.2.6.1 Market Trends
    • 10.2.6.2 Market Forecast
  • 10.2.7 Others
    • 10.2.7.1 Market Trends
    • 10.2.7.2 Market Forecast
• 10.3 Europe
  • 10.3.1 Germany
    • 10.3.1.1 Market Trends
    • 10.3.1.2 Market Forecast
  • 10.3.2 France
    • 10.3.2.1 Market Trends
    • 10.3.2.2 Market Forecast
  • 10.3.3 United Kingdom
    • 10.3.3.1 Market Trends
    • 10.3.3.2 Market Forecast
  • 10.3.4 Italy
    • 10.3.4.1 Market Trends
    • 10.3.4.2 Market Forecast
  • 10.3.5 Spain
    • 10.3.5.1 Market Trends
    • 10.3.5.2 Market Forecast
  • 10.3.6 Russia
    • 10.3.6.1 Market Trends
    • 10.3.6.2 Market Forecast
  • 10.3.7 Others
    • 10.3.7.1 Market Trends
    • 10.3.7.2 Market Forecast
• 10.4 Latin America
  • 10.4.1 Brazil
    • 10.4.1.1 Market Trends
    • 10.4.1.2 Market Forecast
  • 10.4.2 Mexico
    • 10.4.2.1 Market Trends
    • 10.4.2.2 Market Forecast
  • 10.4.3 Others
    • 10.4.3.1 Market Trends
    • 10.4.3.2 Market Forecast
• 10.5 Middle East and Africa
  • 10.5.1 Market Trends
  • 10.5.2 Market Breakup by Country
  • 10.5.3 Market Forecast

11 SWOT Analysis

• 11.1 Overview
• 11.2 Strengths
• 11.3 Weaknesses
• 11.4 Opportunities
• 11.5 Threats

12 Value Chain Analysis

13 Porters Five Forces Analysis

• 13.1 Overview
• 13.2 Bargaining Power of Buyers
• 13.3 Bargaining Power of Suppliers
• 13.4 Degree of Competition
• 13.5 Threat of New Entrants
• 13.6 Threat of Substitutes

14 Price Analysis

15 Competitive Landscape

• 15.1 Market Structure
• 15.2 Key Players
• 15.3 Profiles of Key Players
  • 15.3.1 Andrology Solutions
    • 15.3.1.1 Company Overview
    • 15.3.1.2 Product Portfolio
  • 15.3.2 CinnaGen Co.
    • 15.3.2.1 Company Overview
    • 15.3.2.2 Product Portfolio
  • 15.3.3 Halotech DNA
    • 15.3.3.1 Company Overview
    • 15.3.3.2 Product Portfolio
  • 15.3.4 SCSA Diagnostics Inc.
    • 15.3.4.1 Company Overview
    • 15.3.4.2 Product Portfolio
  • 15.3.5 Vitrolife
    • 15.3.5.1 Company Overview
    • 15.3.5.2 Product Portfolio
    • 15.3.5.3 Financials
  • 15.3.6 Zydus Lifesciences Limited
    • 15.3.6.1 Company Overview
    • 15.3.6.2 Product Portfolio
    • 15.3.6.3 Financials
    • 15.3.6.4 SWOT Analysis
  • 15.3.7 Intas Pharmaceuticals Ltd.
    • 15.3.7.1 Company Overview
    • 15.3.7.2 Product Portfolio
  • 15.3.8 Endo International plc
    • 15.3.8.1 Company Overview
    • 15.3.8.2 Product Portfolio
    • 15.3.8.3 Financials
    • 15.3.8.4 SWOT Analysis