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시장보고서
상품코드
1831993
펩티드 치료제 시장 규모, 점유율, 동향, 예측 : 유형, 제조업체 유형, 합성 기술, 투여 경로, 용도, 지역별(2025-2033년)Peptide Therapeutics Market Size, Share, Trends and Forecast by Type, Type of Manufacturer, Synthesis Technology, Routes of Administration, Application, and Region, 2025-2033 |
세계의 펩티드 치료제 시장 규모는 2024년에 461억 7,000만 달러에 달했습니다. 앞으로 IMARC Group은 2033년까지 918억 7,000만 달러에 이르며, 2025년부터 2033년까지 7.55%의 연평균 복합 성장률(CAGR)을 나타낼 것으로 예측했습니다. 현재 북미는 시장을 독점하고 있으며 2024년에는 약 40.9%의 큰 시장 점유율을 차지했습니다. 이 시장을 견인하고 있는 것은 암, 대사성 질환, 감염증의 유병률 증가이며, 표적을 좁힌 효율적인 치료에 대한 수요의 고조를 촉진하고 있습니다. 펩티드 합성 기술, 약물 전달 시스템, 생체이용률 강화의 발전이 연구와 상업적 채용을 가속화하고 있습니다. 게다가 유리한 규제 당국의 승인, 바이오의약품에 대한 투자 증가, 맞춤형 의료에의 응용 확대가 펩티드 치료제 시장 점유율을 확대하는 주요 요인이 되고 있습니다.
이 시장은 펩티드 신약 개발에 있어서의 인공지능(AI)이나 계산 모델링의 통합 등, 지속적인 진보에 의해 견인되고 있어 효능이 향상된 생물활성 서열의 신속한 동정이 가능해지고 있습니다. 또한 대사성 질환과 감염을 대상으로 한 임상시험 파이프라인의 확대가 수요를 더욱 강화하고 있습니다. 이에 더해 고상 펩티드 합성(SPPS)이나 하이브리드 합성법 등의 제조 능력에 대한 투자가 확대되고 있어 비용 효율적인 스케일 업이 용이해져 시장에 탄력을 주고 있습니다. 예를 들어, 코덴 파마는 2025년 4월 3일, 세계 펩티드 생산 능력을 확대하기 위해 10억 유로(약 11억 달러)를 넘는 전략적 투자를할 것이라고 발표했습니다. 이 회사의 성장 의욕에는 2만 6,000평방미터의 제조 공간과 3만L의 고상 펩티드 합성(SPPS) 능력의 추가가 포함됩니다. 또한 바이오테크놀러지 신흥기업과 주요 제약회사와의 전략적 제휴가 기술 혁신과 상업화의 가속을 지원하고 있습니다.
미국에서는 희귀질환 치료를 목적으로 한 정부의 이니셔티브로 시장이 기세를 늘리고 있습니다. 업계 보고서에 따르면 미국 FDA는 희귀질환의 의약품 개발에서 스폰서를 지원하기 위해 일부 임상시험에 재정 지원을 실시했습니다. 2024년 10월 FDA는 3상 시험 1건을 포함한 2024 회계연도 신규 임상시험 7건에 대한 자금 지원을 발표하고 4년간 총액 1,720만 달러를 할당했습니다. 이러한 공공 부문의 투자는 초기 단계의 R&D 활동을 강화하고 희귀 및 복잡한 질병에 대응하는 펩티드 기반 치료법의 진보에 유리한 환경을 만드는 데 기여합니다. 게다가, 맞춤형 의료의 보급이 진행되고 있는 것도, 펩티드 기반의 정밀 요법의 필요성을 높이고 있습니다. 이외에도 펩티드에 특화된 능력을 가진 CRO와 CDMO의 존재로 기업은 전임상 단계부터 상업 단계까지 효율적으로 진행할 수 있습니다. 또한 낮은 침습 약물 전달에 대한 관심 증가가 주사제와 경피 펩티드 제제의 개발을 뒷받침하고 있습니다. 이와는 별도로, 펩티드 후보에 대한 패스트트랙이나 획기적인 치료제 지정 등 FDA의 규제상의 지원책이 시장 진입을 더욱 가속화하고 있습니다.
만성 질환의 유병률 증가
암, 당뇨병, 심혈관 질환 등 만성 질환의 유병률 증가는 시장을 활성화시키는 주요 요인입니다. NCBI에 따르면 세계 암 환자 수는 크게 증가하고 2050년에는 3,530만명에 달할 것으로 예측되고 있으며, 2022년에 예상되는 2,000만명보다 76.6% 증가하게 될 전망입니다. 높은 특이성과 정확한 생물학적 과정을 표적으로 하는 능력으로 알려진 펩티드는 종종 장기적이고 효과적인 관리 솔루션이 필요한 만성 질환에 대한 유망한 치료 옵션을 제공합니다. 이에 따라 라이프스타일과 관련된 건강상태 증가와 세계적인 노령화로 혁신적인 표적 치료제에 대한 수요가 높아지고 있습니다. 펩티드 치료제는 기존의 저분자 의약품에 비해 부작용을 최소화하는 독자적인 작용기전에 의해 이 요구에 부합하고 있습니다. 게다가 정부와 제약 부문에 의한 R&D(R&D) 투자는 신규 펩티드의 창출을 뒷받침하고 치료 가능성을 확대하고 있습니다. 또한, 펩티드의 합성, 제형화 및 전달에 있어서의 진보는 생체이용률과 안정성을 향상시켜 시장에 긍정적인 영향을 미치고 있습니다. 그 결과, 만성 질환 관리에서 중요한 미충족 요구에 대응하고, 시장은 강력하게 성장하고 있습니다.
펩티드 합성 및 전달 기술의 발전
펩티드 합성과 약물 전달 기술의 끊임없는 진보는 펩티드 치료제의 개발과 효능을 크게 지원합니다. 고상 펩티드 합성(SPPS) 및 자동 합성 플랫폼과 같은 혁신적인 기술은 고품질 펩티드의 생산을 간소화하고, 보다 효율적이고 비용 효율적입니다. 또한, 나노입자 제형 및 경피 흡수 패치와 같은 전달 시스템의 개선으로 펩티드의 안정성 및 생체이용률에 관한 어려움이 해결되고 있으며, 펩티드 치료제 시장 전망은 밝을 것으로 예측됩니다. 이외에도 이러한 혁신은 펩티드의 치료 가능성을 높일 뿐만 아니라 종양학, 내분비학, 면역학 등 다양한 의료 분야에의 응용을 확대합니다. 한 업계 보고서에 따르면 2023년부터 2024년 사이에 ClinicalTrials.gov에서 감염, 암 예방, 치료를 위한 펩티드 백신을 채용한 임상시험이 200건 가까이 기록되어 있습니다. 이러한 진보가 진화를 계속하는 가운데 신규하고 효과적인 펩티드 기반 치료법의 개발을 지원함으로써 시장의 추진력이 될 것으로 기대되고 있습니다.
맞춤형 의료에 대한 관심 증가
맞춤형 의료에 대한 관심 증가는 세계 시장의 또 다른 큰 성장 촉진요인으로 작용하고 있습니다. 펩티드 치료제 시장 분석에 따르면, 펩티드 치료제 시장은 유전적, 환경적, 라이프스타일 요인에 기초하여 환자에게 약물을 맞춤화하는 개인화된 의료에 의해 성장하고 있습니다. 펩티드는 개별 환자에게 특정한 특정 경로 및 생물학적 마커를 표적으로 설계할 수 있기 때문에 이 접근법에 특히 적합합니다. 유전체학 및 바이오마커 연구의 시작은 펩티드 기반 치료가 효과적인 환자 집단의 확인을 용이하게 합니다. 환자의 결과를 개선하고 부작용을 최소화하기 위한 개인화 치료의 가치가 건강 관리 시스템에서 점점 더 인식됨에 따라, 펩티드 치료제의 요구가 증가할 것으로 예측됩니다. 이 맞춤형 의료로의 전환은 제약 업계의 미래 상황을 형성하고 있습니다. FDA에 따르면 2014년 이후 승인된 신약의 25% 이상이 맞춤형 치료에 사용되고 있습니다. 한 업계 보고서에서는 고혈압 환자의 85%, 2형 당뇨병 환자의 80%가 표준 치료에서는 65%였지만, 개별화 접근법은 목표 임상 결과에 도달하고 있다고 강조합니다.
The global peptide therapeutics market size was valued at USD 46.17 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 91.87 Billion by 2033, exhibiting a CAGR of 7.55% during 2025-2033. North America currently dominates the market, holding a significant market share of around 40.9% in 2024. The market is driven by the growing prevalence of cancer, metabolic disorders, and infectious diseases, prompting increased demand for targeted and efficient treatments. Advancements in peptide synthesis technologies, drug delivery systems, and bioavailability enhancements are accelerating research and commercial adoption. Additionally, favorable regulatory approvals, rising investments in biopharmaceutical, and expanding applications in personalized medicine are key factors augmenting the peptide therapeutic market share.
The market is driven by continual advancements, including the integration of artificial intelligence (AI) and computational modeling in peptide drug discovery, enabling faster identification of bioactive sequences with improved efficacy. Additionally, expanding clinical trial pipelines for metabolic and infectious diseases further reinforces demand. Besides this, growing investments in manufacturing capabilities, including solid-phase peptide synthesis (SPPS) and hybrid synthesis methods, are facilitating cost-effective scale-up and providing an impetus to the market. For instance, on April 3, 2025, CordenPharma announced a strategic investment of more than EUR 1 Billion (about USD 1.1 Billion) to expand its global peptide production capacity. The company's growth ambitions include adding 26,000 square meters of manufacturing space and 30,000 L of solid-phase peptide synthesis (SPPS) capability. Moreover, strategic partnerships between biotech startups and large pharmaceutical firms are supporting accelerated innovation and commercialization.
In the United States, the market is gaining momentum through targeted government initiatives aimed at rare disease treatment. According to industry reports, the U.S. FDA provides financial support for a select number of clinical trials to aid sponsors in developing medicinal products for rare conditions. In October 2024, the FDA announced funding for seven new clinical studies in fiscal year 2024, including one Phase 3 trial, with a total allocation of USD 17.2 Million over four years. This public sector investment enhances early-stage research and development activities, contributing to a more favorable environment for the advancement of peptide-based therapies addressing rare and complex diseases. Furthermore, the increasing prevalence of personalized medicine is also fueling the need for peptide-based precision therapies. In addition to this, the robust presence of CROs and CDMOs with specialized peptide capabilities allows companies to progress from preclinical to commercial stages efficiently. Also, rising interest in minimally invasive drug delivery has driven the development of injectable and transdermal peptide formulations. Apart from this, supportive FDA regulatory pathways, including fast-track and breakthrough therapy designations for peptide candidates, have further accelerated market entry.
Increasing Prevalence of Chronic Diseases
The increasing prevalence of chronic diseases, such as cancer, diabetes, and cardiovascular conditions, is a primary factor providing an impetus to the market. According to the NCBI, global cancer cases are projected to rise significantly, reaching 35.3 million by 2050, representing a 76.6% increase over the expected 20 million cases in 2022. Peptides, known for their high specificity and ability to target precise biological processes, offer promising treatment options for chronic diseases, which often require long-term and effective management solutions. In line with this, with a rise in lifestyle-related health conditions and an aging global population, the demand for innovative, targeted therapies is on the rise. Peptide therapeutics align well with this need due to their unique mechanisms of action, which minimize side effects as compared to traditional small-molecule drugs. Moreover, government and pharmaceutical sector investments in research and development (R&D) drive the creation of novel peptides, expanding treatment possibilities. In addition to this, advancements in peptide synthesis, formulation, and delivery have enhanced their bioavailability and stability, which is positively impacting the market, Consequently, there is a robust peptide therapeutics market growth, addressing critical unmet needs in chronic disease management.
Advancements in Peptide Synthesis and Delivery Technologies
Continual advancements in peptide synthesis and drug delivery technologies are significantly supporting the development and efficacy of peptide therapeutics. Innovative techniques, such as solid-phase peptide synthesis (SPPS) and automated synthesis platforms, have streamlined the production of high-quality peptides, making them more efficient and cost-effective. Moreover, improved delivery systems, such as nanoparticle formulations and transdermal patches, are addressing challenges related to peptide stability and bioavailability, which is expected to create a positive peptide therapeutics market outlook. In addition to this, these technological innovations not only enhance the therapeutic potential of peptides but also expand their applications across various medical fields, including oncology, endocrinology, and immunology. According to an industry report, nearly 200 clinical trials employing peptide vaccines for infectious diseases, cancer prevention, and therapy were documented on ClinicalTrials.gov between 2023 and 2024. As these advancements continue to evolve, they are expected to propel the market by supporting the development of novel and effective peptide-based therapies.
Growing Focus on Personalized Medicine
The increasing emphasis on personalized medicine is acting as another major growth-inducing factor in the market across the globe. According to the peptide therapeutics market analysis, the market for peptide therapies is growing due to personalized medicine, which customizes medicines to patients based on genetic, environmental, and lifestyle factors. Peptides are particularly well-suited for this approach, as they can be designed to target specific pathways and biological markers unique to individual patients. The rise of genomics and biomarker research is facilitating the identification of patient populations that may benefit from peptide-based therapies. As healthcare systems increasingly recognize the value of personalized treatments in improving patient outcomes and minimizing side effects, the need for peptide therapeutics is expected to rise. This shift toward personalized medicine is shaping the future landscape of the pharmaceutical industry. Over 25% of all new drug approvals since 2014 have been used for personalized treatments, according to the FDA. An industry report highlights that 85% of hypertension patients and 80% of type 2 diabetes patients reached target clinical outcomes with personalized approaches, compared to 65% under standard treatments.
Innovative leads the market with around 64.0% of market share in 2024. These therapeutics are typically first-in-class or best-in-class drugs, characterized by novel mechanisms of action, enhanced targeting abilities, and improved pharmacokinetic profiles. Unlike generic or biosimilar peptides, innovative peptides are developed through advanced technologies such as solid-phase peptide synthesis, recombinant DNA methods, and peptide conjugation platforms. Their importance is underscored by their high therapeutic value across complex diseases, including cancer, metabolic disorders, and rare genetic conditions. Apart from this, pharmaceutical companies are extensively investing in research and development (R&D) for innovative peptides due to their potential for exclusivity and premium pricing. Furthermore, regulatory incentives like orphan drug designations and fast-track approvals have boosted their commercial viability. As the demand for precision medicine and biologically targeted therapies grows, the innovative segment remains a cornerstone for shaping the future trajectory of peptide drug development and commercialization.
In-house leads the market with around 64.4% of market share in 2024. In-house manufacturing offers pharmaceutical companies' greater control over production quality, timelines, and intellectual property. By maintaining internal capabilities, companies can ensure consistency in complex synthesis processes, particularly crucial for high-purity peptide drugs that require stringent quality standards. In-house facilities allow for tighter integration between research and development (R&D) and manufacturing, enabling faster transitions from clinical development to commercial production. This also enhances flexibility in scaling production based on demand and allows quicker implementation of process improvements or modifications. For companies developing innovative or proprietary peptides, in-house manufacturing safeguards sensitive formulations and reduces reliance on external partners. It also helps in managing regulatory compliance more effectively, especially for therapies targeting rare diseases or requiring specialized delivery methods. As peptide drugs become more complex and personalized, the role of in-house manufacturing is expected to expand in the market.
Liquid phase peptide synthesis leads the market with around 44.3% of market share in 2024. It is an important technology to produce simple peptides at a large scale. This method, which involves synthesizing peptides in solution using soluble reactants, offers advantages such as better reaction monitoring, easier purification of intermediates, and cost-effectiveness for high-volume manufacturing. LPPS is especially useful when producing peptides that do not require complex modifications or sequences, making it a practical choice for established, off-patent therapeutic peptides or early-stage development. Despite the broader industry shift toward solid phase peptide synthesis (SPPS) for complex molecules, LPPS continues to be relevant due to its scalability, efficiency in batch processing, and lower reagent cost. Manufacturers with expertise in LPPS achieve high yields with consistent purity, which is critical for meeting regulatory standards. Its continued application reinforces its role as a foundational technology in the peptide production landscape.
Parental leads the market with around 88.7% of market share in 2024. Administering peptides via injection, typically intravenous, subcutaneous, or intramuscular, ensures rapid absorption, controlled dosing, and optimal therapeutic concentration in the bloodstream. This route bypasses enzymatic degradation and first-pass metabolism, which are major limitations for oral formulations. In the market, parenteral delivery supports a wide range of treatments, including hormone regulation, cancer therapy, metabolic disorders, and rare disease management. Many blockbuster peptide drugs, such as insulin analogs and GLP-1 receptor agonists, rely on subcutaneous administration for long-term disease control. Advances in delivery devices, including auto-injectors and pre-filled syringes, have also improved patient compliance and convenience. As research continues into alternative delivery methods, parenteral administration remains the standard for ensuring therapeutic efficacy and safety of peptide-based treatments.
Metabolic disorders lead the market with around 27.9% of market share in 2024 due to the rising global incidence of conditions like diabetes, obesity, and metabolic syndrome. Peptide-based drugs offer distinct advantages, such as high specificity, low toxicity, and the ability to modulate complex biological pathways, making them ideal for treating these disorders. One of the most notable examples is the widespread use of GLP-1 receptor agonists like semaglutide and liraglutide in managing type 2 diabetes and obesity. The demand for such treatments is accelerating as lifestyle-related metabolic diseases become more prevalent across both developed and emerging economies. Additionally, advancements in peptide synthesis and drug delivery systems are expanding the therapeutic potential of peptides, enhancing their stability and bioavailability. This has encouraged pharmaceutical companies to invest heavily in research and development (R&D) for peptide drugs targeting metabolic pathways, driving innovation and growth in this segment of market.
In 2024, North America accounted for the largest market share of over 40.9% driven by a strong pharmaceutical industry, advanced healthcare infrastructure, and high research and development (R&D) investment. The region, particularly the United States, hosts a concentration of major biotech firms and research institutions actively developing peptide-based drugs for cancer, metabolic disorders, and rare diseases. Regulatory support from agencies like the FDA, along with streamlined approval pathways for orphan drugs and breakthrough therapies, has accelerated market entry for innovative peptides. Additionally, the region benefits from a high prevalence of chronic diseases, growing demand for personalized medicine, and favorable reimbursement structures that support the adoption of advanced therapies. The region also sees active collaborations between academic centers and pharmaceutical companies, encouraging continuous innovation in peptide drug development. With a strong clinical trial ecosystem and rising patient awareness, North America remains a key contributor to both the revenue and innovation pipeline of the global market.
United States Peptide Therapeutics Market Analysis
In 2024, the United States holds a substantial share of around 86.50% of the market share in North America. The market in the United States is primarily driven by increased research and development (R&D) investments by pharmaceutical and biotechnology companies. In line with this, the heightened presence of advanced healthcare infrastructure and supportive reimbursement frameworks is accelerating the clinical adoption of peptide-based therapies. The rising incidence of chronic illnesses, including metabolic and cardiovascular disorders, requiring precise and targeted treatment solutions, is supporting market demand. According to the American Heart Association's 2025 statistical report, the United States recorded 941,652 cardiovascular disease (CVD)-related deaths in 2022, marking an increase of over 10,000 deaths from the 931,578 reported in 2021. Furthermore, growing public and private funding for rare disease therapeutics, encouraging peptide-centric pipelines, is propelling growth in the market. The rapid integration of artificial intelligence and machine learning into drug discovery processes, enabling rapid identification of therapeutic peptide candidates, is contributing to industry innovation and market appeal. Similarly, numerous collaborations between academic institutions and industry players that augment translational research and commercialization prospects are strengthening market presence. Additionally, increased reliance on contract manufacturing organizations for scalable peptide production is optimizing supply chains and bolstering product sales.
Europe Peptide Therapeutics Market Analysis
The European market is experiencing growth due to strong regulatory incentives for orphan and specialty drugs, which are promoting innovation in peptide-based treatments. In accordance with this, increased funding through Horizon Europe and national research initiatives is accelerating the clinical development of peptide formulations. Similarly, the rising burden of age-related conditions, including osteoporosis and neurodegenerative diseases, is increasing the peptide therapeutics market demand. According to NCBI, the annual number of osteoporotic fractures in the European Union was estimated at 4.28 million in 2019 and is projected to rise to 5.34 million by 2034, indicating a significant increase in fracture-related healthcare needs across the region. The growing manufacturing footprint in countries such as Germany and Switzerland, enhancing production efficiency, is supporting market scalability. Furthermore, the rising number of EMA approvals for novel peptide drugs, improving accessibility and clinical adoption, is bolstering market reach. The rapid integration of peptide-based solutions into antimicrobial resistance (AMR) strategies aligned with EU health goals is further strengthening market demand. Besides this, robust academic research in peptide chemistry and translational science, fostering innovation pipelines, is expanding therapeutic potential in the market.
Asia Pacific Peptide Therapeutics Market Analysis
The market in the Asia Pacific is gaining momentum due to rising healthcare expenditure across emerging economies, improving access to specialized treatments. In addition to this, the increasing prevalence of lifestyle-related disorders, such as diabetes and obesity, requires targeted therapeutic approaches, which are also driving product demand. As per an industry report, India leads globally with 212 million people living with diabetes, surpassing China's 148 million. Also, India has the highest number of individuals over the age of 30 with untreated diabetes, estimated at 133 million, compared to 78 million in China. Similarly, the rapid scale-up of domestic pharmaceutical manufacturing in countries like India, China, and South Korea, enabling cost-efficient peptide production, is enhancing market competitiveness. Moreover, the ongoing establishment of regional research and development (R&D) centers by global pharmaceutical firms supporting innovation and technology exchange is strengthening the market landscape. Apart from this, growing public awareness of personalized medicine and preventive care, particularly in the urban population, is accelerating the product uptake across a range of treatment areas.
Latin America Peptide Therapeutics Market Analysis
In Latin America, the market is progressing, attributed to the increasing burden of chronic diseases such as diabetes and cardiovascular disorders. Similarly, significant improvements in regional healthcare systems, enhancing access to specialty therapies, are supporting the broader adoption of peptide-based drugs. The Federal Government of Brazil increased the Ministry of Health's budget for specialized treatments by 34% between 2022 and 2024, raising the allocation from BRL 54.9 Billion in 2022 (about USD 10.98 Billion) to BRL 74.7 Billion (about USD 14.94 Billion) in 2024. Furthermore, various collaborations between domestic pharmaceutical firms and global players, facilitating technology transfer and localized production, are strengthening market infrastructure. Moreover, active participation in international regulatory alignment efforts, reducing barriers to entry for innovative therapies, is streamlining approval processes and accelerating market expansion across the region.
Middle East and Africa Peptide Therapeutics Market Analysis
In the Middle East and Africa, the market is advancing, supported by the growing incidences of lifestyle-related diseases such as obesity and type 2 diabetes, particularly in urban centers. According to the World Obesity Federation, the number of obese adults in the Middle East and Africa is projected to increase by over 200%, rising from 11.8 million to 37.2 million by 2030. Additionally, a rise in government-led healthcare reforms and increased public investment in specialty medical services are improving access to advanced treatments in the market. The strategic expansion of pharmaceutical distribution networks across the Gulf and Sub-Saharan regions is enhancing product availability. Moreover, growing participation in international clinical research collaborations is fostering innovation and promoting the integration of peptide-based therapies into national treatment protocols.
The market is characterized by intense competition driven by technological advancements, growing demand for targeted treatments, and expanding therapeutic applications. Several players are focusing on innovative drug delivery methods, including oral, transdermal, and nanoparticle-based systems, to overcome challenges such as enzymatic degradation and short half-life. Biosynthetic techniques and solid-phase peptide synthesis are refined for scalability and cost efficiency. According to the peptide therapeutics market forecast, the sector is expected to grow steadily in the future years, driven by increased research and development (R&D) spending and favorable regulatory environments for biologics. Peptides have promising clinical applications in oncology, endocrinology, and infectious disorders. Market participants are also engaging in strategic collaborations, licensing deals, and contract manufacturing partnerships to strengthen their portfolios. The market landscape is further shaped by patent expiries, prompting an influx of generics and biosimilars. The emphasis is shifting toward long-acting and multifunctional peptides, reflecting the push for improved patient outcomes and competitive differentiation.