바이오서저리 시장 보고서 : 제품별, 원료별, 용도별, 최종사용자별, 지역별(2026-2034년)

The global biosurgery market size reached USD 15.6 Billion in 2025. Looking forward, IMARC Group expects the market to reach USD 25.8 Billion by 2034, exhibiting a growth rate (CAGR) of 5.54% during 2026-2034. North America was the largest regional market for biosurgery owing to the advanced healthcare infrastructure, significant investments in research and development (R&D) activities, and the presence of leading players who drive innovation and expansion. Moreover, the increasing surgical procedures, technological advancements in medical devices, and growing demand for effective wound management in complex surgeries is enhancing surgical outcomes and recovery times for patients across the globe.

The market for biosurgery is undergoing immense changes with the advancement of medical technologies and evolving healthcare requirements. The growing promise and complexity of biosurgical technologies are stimulating more interaction between the medical sector and academic centers. Academic institutions and research institutes are taking center stage in investigating new biologic materials, creating new surgical methods, and testing the efficacy of new products through clinical trials. This cooperative setting is developing the swift growth of innovative biosurgical solutions, as manufacturers and scientists collaborate to advance new products to market more quickly. In addition, academic centers play an active role in training future surgeons about the advantages and applications of biosurgery. With increasing numbers of healthcare professionals being trained in the handling of biologically derived products, the uptake and acceptance of these products in clinical practice is also growing. Collaborative research endeavors are also refining the understanding of complicated biological mechanisms, and useful insights are being utilized in developing improved biosurgical solutions that can benefit various patient groups.

Biosurgery Market Trends:

Technological Progress in Biosurgical Products

Technological developments are contributing tremendously to the faster growth of the biosurgery market. Ongoing improvements in biologic materials are increasing the efficiency of products like hemostats, adhesives, and tissue-engineered products. Companies are targeting more efficient, biocompatible, and sustainable surgical products. For instance, advances in bioactive materials that promote faster wound healing and enhance tissue regeneration are revolutionizing the space. In addition, development in 3D printing technology is facilitating the production of personalized implants and surgical instruments, making way for more efficient and tailor-made surgical interventions. These developments not only enhance surgical performance but also make biosurgical products more accessible and affordable. With new technologies coming onto the scene, the scope of biosurgical solutions is increasing, treating more types of surgical requirements and facilitating improved patient care across a variety of medical specialties. 3D Systems revealed that, in partnership with University Hospital Basel (Switzerland), the Company's exclusive point-of-care additive manufacturing solution is utilized to create the world's first 3D-printed PEEK facial implant compliant with Medical Device Regulation (MDR). Prof. Florian Thieringer and Dr. Neha Sharma, along with their team of biomedical engineers, effectively created and produced a tailored device to meet a patient's specific requirement utilizing 3D Systems technology and manufacturing knowledge. This implant was utilized in a successful operation finished at the hospital on March 18, 2025.

Increased Demand for Minimally Invasive Procedures

The heightened need for minimally invasive procedures is one of the fundamental growth drivers in the market. As medical practitioners and patients aim to minimize the recovery time and risks involved with conventional open surgeries, more minimally invasive procedures are being performed. These surgeries, in most cases, entail smaller cuts, less trauma to the tissues around them, and less blood loss, resulting in shorter recovery periods and fewer complications. Biosurgical items, including hemostats and biologic adhesives, are part of these procedures as they facilitate better tissue sealing and bleeding control with accuracy. Surgeons are also employing biologic materials for better wound healing and the prevention of chances of infection in minimally invasive procedures. With the trend toward minimally invasive procedures in all specialties, the need for biosurgical solutions that enable these procedures is increasing, further fueling the market growth. The publisher predicts that the global minimally invasive surgery market is anticipated to reach USD 94.9 Billion by 2033.

Aging Global Population

The aging world population is playing a huge role in driving the biosurgery market. As per an article published by the World Health Organization (WHO) in 2025, the number of people aged 60 and above is anticipated to increase to 1.4 billion by 2030. As individuals grow older, they tend to develop a variety of ailments that call for surgeries, including joint replacements, cardiovascular procedures, and orthopedic procedures. Elderly patients generally possess slower recovery mechanisms and are more prone to surgical and post-surgical complications. These issues are being dealt with by biosurgical devices like tissue-engineered grafts, wound healing products, and biologic adhesives that are facilitating quicker recovery, minimizing the risk of infection, and optimizing tissue regeneration. Second, as older patients have more chronic diseases that necessitate continuous medical care, the need for sophisticated biosurgical solutions is also on the increase. The elderly population worldwide is therefore fueling the market growth since healthcare systems are increasingly embracing advanced technologies to enhance surgical outcomes and reduce recovery periods for older patients.

Biosurgery Market Growth Drivers:

Increasing Healthcare Costs and Sensitivity to Advanced Surgical Solutions

Health care spending is rising globally, and advanced surgical solutions, such as biosurgical products, are increasingly recognized as having advantages. Both healthcare professionals and patients are more aware today about the benefits that biologically engineered surgical products provide over conventional synthetic ones. These include lower healing times, fewer complications, and better biocompatibility, which are important for maximizing surgical outcomes. Healthcare systems, especially those in the developed world, are now investing heavily in such sophisticated solutions to enhance care quality and contain the costs of long-term recovery and complications. With more medical specialists adopting sophisticated surgical methods, biosurgical devices like bioactive dressings, tissue grafts, and biodegradable sutures are becoming part and parcel of a variety of procedures.

Increasing Incidence of Chronic Diseases and Surgical Surgeries

The increasing incidence of chronic diseases, including diabetes, cardiovascular disease, and obesity, is propelling the market growth. Most chronic diseases result in conditions that are likely to be treated with surgery, like diabetic ulcers, vascular surgeries, and joint replacements. As these conditions become more prevalent, the demand for novel surgical products that enhance faster recovery and lower complications is increasing. Biosurgical products like biologic solutions for wound care, tissue repair solutions, and hemostatics are finding growing use in surgeries to provide improved patient outcomes for chronic patients. For instance, biologic grafts and dressings play a crucial role in healing chronic, complicated wounds that are slow to heal in diabetic patients. With the growing global burden of chronic disease, the need for biosurgical products is spreading wide, making these products integral parts of contemporary surgical procedures.

Expanding Healthcare Access in Emerging Markets

Increased access to healthcare in emerging economies is bolstering the market growth. The developing world's improvement in healthcare infrastructure and access to sophisticated medical technology continues to catalyze the demand for biosurgical products. These nations are observing increased rates of surgeries in orthopedic, cardiovascular, and trauma care segments, which are driving the use of biosurgery products. As the populations become increasingly accessible to quality healthcare, biosurgical products with improved surgical outcomes are finding increased applications. Furthermore, numerous governments and healthcare systems are investing in projects aimed at enhancing surgical care and minimizing the incidence of medical complications, thus creating additional demand for biologically derived surgical solutions.

Biosurgery Market Segmentation:

The publisher provides an analysis of the key trends in each segment of the market, along with forecasts at the global, regional, and country levels for 2026-2034. Our report has categorized the market based on product, source, application and end user.

Breakup by Product:

• Bone-Graft Substitutes
• Soft-Tissue Attachments
• Hemostatic Agents
• Surgical Sealants and Adhesives
• Adhesion Barriers
• Staple Line Reinforcement

Bone-graft substitutes account for the majority of the market share

Bone-graft substitutes are crucial alternatives to bone grafting. These stand-ins play a critical role in many surgical operations, supporting bone regeneration and repair in orthopedics, trauma, spine surgery, and dentistry applications. They are intended to minimize the risk of donor site morbidity and infection by promoting bone development and replacing conventional autografts, which require removing bone from the patient's own body. Furthermore, the expansion is driven by the increasing frequency of bone and joint problems, the need for less intrusive operations, and developments in biomaterial technology. The growth of this market segment is also fueled by the creation of novel synthetic and composite grafts with improved osteoconductive and osteoinductive qualities. For instance, on 23 May 2023, Royal Biologics, Inc., a company focused on advanced cellular and autologous technologies for improved surgical outcomes, unveiled BIO-REIGN 3D. This innovative bone graft substitute is the first to use a natural hyper-crosslinked carbohydrate polymer. It is designed to enhance bone grafting procedures, and this proprietary technology is introduced alongside Royal Biologics' licensing agreement for Molecular Matrix's patented Osteo-P BGS technology.

Breakup by Source:

• Natural/Biologics Products
• Synthetic Products

Natural/biologics products hold the largest share of the industry

According to the biosurgery market overview, natural/biologics represent the largest segment due to their effective healing properties and biocompatibility. These products, derived from substances that are naturally present in the human body or other biological sources, include fibrin sealants, collagen-based matrices, and chitosan-based solutions. Additionally, natural/biologics product's ability to mimic natural physiological processes significantly reduces the risk of rejection and adverse reactions, making them highly preferred in surgical procedures. Moreover, market dominance is further supported by advancements in biotechnology that enhance the safety and efficacy of these materials. Consequently, the increasing demand for minimally invasive surgeries, coupled with the growing prevalence of chronic diseases requiring complex surgeries, continues to drive the growth of natural/biologics products in the market.

Breakup by Application:

• Orthopedic Surgery
• General Surgery
• Neurological Surgery
• Cardiovascular Surgery
• Gynecological Surgery
• Others

Neurological surgery represents the leading market segment

Neurological surgeries are complex and require critical precision. Additionally, biosurgery products, such as sealants, hemostatic agents, and adhesion barriers, are extensively used in neurological procedures to manage bleeding, seal tissues, and reduce post-operative complications. Moreover, the rising prevalence of neurological disorders, such as brain tumors, epilepsy, and Parkinson's disease, coupled with advancements in neurosurgical techniques are escalating the demand in this segment. Besides, the widespread adoption of minimally invasive (MI) surgeries, which require highly effective biosurgical solutions to enhance patient outcomes is further driving the biosurgery market growth. This trend is supported by technological innovations in biosurgery products, aimed at improving surgical outcomes and reducing recovery times.

Breakup by End User:

• Hospitals
• Clinics
• Others

Hospital exhibits a clear dominance in the market

Hospitals offer a wide array of surgical procedures that frequently utilize biosurgical products. These products, which include hemostatic agents, surgical sealants, and adhesives, are integral in managing intraoperative and postoperative bleeding and promoting tissue healing. Additionally, hospitals' capacity to handle high patient volumes and conduct complex surgeries increases biosurgery demand. Additionally, the constant advancements in surgical techniques and the increasing preference for minimally invasive surgeries further amplify the utilization of biosurgical solutions in hospital settings.

Breakup by Region:

• North America
• United States
• Canada
• Asia-Pacific
• China
• Japan
• India
• South Korea
• Australia
• Indonesia
• Others
• Europe
• Germany
• France
• United Kingdom
• Italy
• Spain
• Russia
• Others
• Latin America
• Brazil
• Mexico
• Others
• Middle East and Africa

North America leads the market, accounting for the largest biosurgery market share

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America was the largest regional market for biosurgery.

North America is the leading region due to the advanced healthcare infrastructure, significant investments in research and development (R&D) activities, and the presence of leading players who drive innovation and expansion. Additionally, the increasing prevalence of chronic diseases and the growing elderly population in North America contribute to a higher demand for biosurgical products. According to the biosurgery market forecast, these factors, combined with favorable government policies and a strong trend toward minimally invasive surgeries, will continue to strengthen North America's leading position in the global biosurgery market.

Competitive Landscape:

• The biosurgery market research report has also provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the major market players in the industry include B. Braun Melsungen AG, Baxter International Inc., Becton Dickinson and Company, CryoLife Inc., CSL Limited, Hemostasis LLC, Integra Lifesciences Holdings Corporation, Johnson & Johnson, Medtronic plc, Pfizer Inc., Sanofi S.A., Smith & Nephew plc, Stryker Corporation and Surgalign Spine Technologies Inc.
• At present, biosurgery market players are actively enhancing market growth through a combination of strategic collaborations, innovative product launches, and expansions into new geographical markets. These companies invest heavily in research and development (R&D) to introduce advanced products that meet the increasing demands of minimally invasive surgeries and improved wound care. Additionally, market players are focusing on obtaining regulatory approvals across different regions, which helps in expanding their global footprint and accessing new markets. These strategies collectively contribute to the robust growth and resilience of the biosurgery market. For instance, in 2023, AROA Biosurgery Ltd. revealed the release of a new retrospective pilot case series that explores the use of Myriad Matrix and Myriad Morcells in the surgical treatment of contaminated volumetric soft tissue defects. It reviewed 13 complex traumatic wounds in 10 patients at a single facility. The study reported an average time of 23.4+-9.2 days for achieving soft tissue coverage and fill, with a median of one product application and no complications among participants. Moreover, the research focused on injuries from motor vehicle accidents, abdominal dehiscence after hernia repair, Fournier's Gangrene, compartment syndrome, and pressure injuries at a US Level 1 trauma center. It found that the Myriad products facilitated effective soft tissue formation with no reported complications, reinforcing the utility of AROA ECM products in trauma care.

Key Questions Answered in This Report:

• How has the global biosurgery market performed so far, and how will it perform in the coming years?
• What are the drivers, restraints, and opportunities in the global biosurgery market?
• What is the impact of each driver, restraint, and opportunity on the global biosurgery market?
• What are the key regional markets?
• Which countries represent the most attractive biosurgery market?
• What is the breakup of the market based on the product?
• Which is the most attractive product in the biosurgery market?
• What is the breakup of the market based on the source?
• Which is the most attractive source in the biosurgery market?
• What is the breakup of the market based on the application?
• Which is the most attractive application in the biosurgery market?
• What is the breakup of the market based on the end user?
• Which is the most attractive end user in the biosurgery market?
• What is the competitive structure of the market?
• Who are the key players/companies in the global biosurgery market?

Table of Contents

1 Preface

2 Scope and Methodology

• 2.1 Objectives of the Study
• 2.2 Stakeholders
• 2.3 Data Sources
  • 2.3.1 Primary Sources
  • 2.3.2 Secondary Sources
• 2.4 Market Estimation
  • 2.4.1 Bottom-Up Approach
  • 2.4.2 Top-Down Approach
• 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

• 4.1 Overview
• 4.2 Key Industry Trends

5 Global Biosurgery Market

• 5.1 Market Overview
• 5.2 Market Performance
• 5.3 Impact of COVID-19
• 5.4 Market Forecast

6 Market Breakup by Product

• 6.1 Bone-Graft Substitutes
  • 6.1.1 Market Trends
  • 6.1.2 Market Forecast
• 6.2 Soft-Tissue Attachments
  • 6.2.1 Market Trends
  • 6.2.2 Market Forecast
• 6.3 Hemostatic Agents
  • 6.3.1 Market Trends
  • 6.3.2 Market Forecast
• 6.4 Surgical Sealants and Adhesives
  • 6.4.1 Market Trends
  • 6.4.2 Market Forecast
• 6.5 Adhesion Barriers
  • 6.5.1 Market Trends
  • 6.5.2 Market Forecast
• 6.6 Staple Line Reinforcement
  • 6.6.1 Market Trends
  • 6.6.2 Market Forecast

7 Market Breakup by Source

• 7.1 Natural/Biologics Products
  • 7.1.1 Market Trends
  • 7.1.2 Market Forecast
• 7.2 Synthetic Products
  • 7.2.1 Market Trends
  • 7.2.2 Market Forecast

8 Market Breakup by Application

• 8.1 Orthopedic Surgery
  • 8.1.1 Market Trends
  • 8.1.2 Market Forecast
• 8.2 General Surgery
  • 8.2.1 Market Trends
  • 8.2.2 Market Forecast
• 8.3 Neurological Surgery
  • 8.3.1 Market Trends
  • 8.3.2 Market Forecast
• 8.4 Cardiovascular Surgery
  • 8.4.1 Market Trends
  • 8.4.2 Market Forecast
• 8.5 Gynecological Surgery
  • 8.5.1 Market Trends
  • 8.5.2 Market Forecast
• 8.6 Others
  • 8.6.1 Market Trends
  • 8.6.2 Market Forecast

9 Market Breakup by End User

• 9.1 Hospitals
  • 9.1.1 Market Trends
  • 9.1.2 Market Forecast
• 9.2 Clinics
  • 9.2.1 Market Trends
  • 9.2.2 Market Forecast
• 9.3 Others
  • 9.3.1 Market Trends
  • 9.3.2 Market Forecast

10 Market Breakup by Region

• 10.1 North America
  • 10.1.1 United States
    • 10.1.1.1 Market Trends
    • 10.1.1.2 Market Forecast
  • 10.1.2 Canada
    • 10.1.2.1 Market Trends
    • 10.1.2.2 Market Forecast
• 10.2 Asia-Pacific
  • 10.2.1 China
    • 10.2.1.1 Market Trends
    • 10.2.1.2 Market Forecast
  • 10.2.2 Japan
    • 10.2.2.1 Market Trends
    • 10.2.2.2 Market Forecast
  • 10.2.3 India
    • 10.2.3.1 Market Trends
    • 10.2.3.2 Market Forecast
  • 10.2.4 South Korea
    • 10.2.4.1 Market Trends
    • 10.2.4.2 Market Forecast
  • 10.2.5 Australia
    • 10.2.5.1 Market Trends
    • 10.2.5.2 Market Forecast
  • 10.2.6 Indonesia
    • 10.2.6.1 Market Trends
    • 10.2.6.2 Market Forecast
  • 10.2.7 Others
    • 10.2.7.1 Market Trends
    • 10.2.7.2 Market Forecast
• 10.3 Europe
  • 10.3.1 Germany
    • 10.3.1.1 Market Trends
    • 10.3.1.2 Market Forecast
  • 10.3.2 France
    • 10.3.2.1 Market Trends
    • 10.3.2.2 Market Forecast
  • 10.3.3 United Kingdom
    • 10.3.3.1 Market Trends
    • 10.3.3.2 Market Forecast
  • 10.3.4 Italy
    • 10.3.4.1 Market Trends
    • 10.3.4.2 Market Forecast
  • 10.3.5 Spain
    • 10.3.5.1 Market Trends
    • 10.3.5.2 Market Forecast
  • 10.3.6 Russia
    • 10.3.6.1 Market Trends
    • 10.3.6.2 Market Forecast
  • 10.3.7 Others
    • 10.3.7.1 Market Trends
    • 10.3.7.2 Market Forecast
• 10.4 Latin America
  • 10.4.1 Brazil
    • 10.4.1.1 Market Trends
    • 10.4.1.2 Market Forecast
  • 10.4.2 Mexico
    • 10.4.2.1 Market Trends
    • 10.4.2.2 Market Forecast
  • 10.4.3 Others
    • 10.4.3.1 Market Trends
    • 10.4.3.2 Market Forecast
• 10.5 Middle East and Africa
  • 10.5.1 Market Trends
  • 10.5.2 Market Breakup by Country
  • 10.5.3 Market Forecast

11 SWOT Analysis

• 11.1 Overview
• 11.2 Strengths
• 11.3 Weaknesses
• 11.4 Opportunities
• 11.5 Threats

12 Value Chain Analysis

13 Porters Five Forces Analysis

• 13.1 Overview
• 13.2 Bargaining Power of Buyers
• 13.3 Bargaining Power of Suppliers
• 13.4 Degree of Competition
• 13.5 Threat of New Entrants
• 13.6 Threat of Substitutes

14 Price Analysis

15 Competitive Landscape

• 15.1 Market Structure
• 15.2 Key Players
• 15.3 Profiles of Key Players
  • 15.3.1 B. Braun Melsungen AG
    • 15.3.1.1 Company Overview
    • 15.3.1.2 Product Portfolio
    • 15.3.1.3 SWOT Analysis
  • 15.3.2 Baxter International Inc.
    • 15.3.2.1 Company Overview
    • 15.3.2.2 Product Portfolio
    • 15.3.2.3 Financials
    • 15.3.2.4 SWOT Analysis
  • 15.3.3 Becton Dickinson and Company
    • 15.3.3.1 Company Overview
    • 15.3.3.2 Product Portfolio
    • 15.3.3.3 Financials
    • 15.3.3.4 SWOT Analysis
  • 15.3.4 CryoLife Inc.
    • 15.3.4.1 Company Overview
    • 15.3.4.2 Product Portfolio
    • 15.3.4.3 Financials
    • 15.3.4.4 SWOT Analysis
  • 15.3.5 CSL Limited
    • 15.3.5.1 Company Overview
    • 15.3.5.2 Product Portfolio
    • 15.3.5.3 Financials
    • 15.3.5.4 SWOT Analysis
  • 15.3.6 Hemostasis LLC
    • 15.3.6.1 Company Overview
    • 15.3.6.2 Product Portfolio
  • 15.3.7 Integra Lifesciences Holdings Corporation
    • 15.3.7.1 Company Overview
    • 15.3.7.2 Product Portfolio
    • 15.3.7.3 Financials
    • 15.3.7.4 SWOT Analysis
  • 15.3.8 Johnson & Johnson
    • 15.3.8.1 Company Overview
    • 15.3.8.2 Product Portfolio
    • 15.3.8.3 Financials
    • 15.3.8.4 SWOT Analysis
  • 15.3.9 Medtronic plc
    • 15.3.9.1 Company Overview
    • 15.3.9.2 Product Portfolio
    • 15.3.9.3 Financials
    • 15.3.9.4 SWOT Analysis
  • 15.3.10 Pfizer Inc.
    • 15.3.10.1 Company Overview
    • 15.3.10.2 Product Portfolio
    • 15.3.10.3 Financials
    • 15.3.10.4 SWOT Analysis
  • 15.3.11 Sanofi S.A.
    • 15.3.11.1 Company Overview
    • 15.3.11.2 Product Portfolio
    • 15.3.11.3 Financials
    • 15.3.11.4 SWOT Analysis
  • 15.3.12 Smith & Nephew plc
    • 15.3.12.1 Company Overview
    • 15.3.12.2 Product Portfolio
    • 15.3.12.3 Financials
    • 15.3.12.4 SWOT Analysis
  • 15.3.13 Stryker Corporation
    • 15.3.13.1 Company Overview
    • 15.3.13.2 Product Portfolio
    • 15.3.13.3 Financials
    • 15.3.13.4 SWOT Analysis
  • 15.3.14 Surgalign Spine Technologies Inc.
    • 15.3.14.1 Company Overview
    • 15.3.14.2 Product Portfolio
    • 15.3.14.3 Financials