세계의 소수성 상호작용 크로마토그래피 시장 - 규모, 점유율, 성장 분석 : 제품 유형별, 샘플 유형별, 최종 사용자별, 지역별 산업 예측(2026-2033년)

Global Hydrophobic Interaction Chromatography Market size was valued at USD 394.32 Million in 2024 and is poised to grow from USD 424.68 Million in 2025 to USD 768.76 Million by 2033, growing at a CAGR of 7.7% during the forecast period (2026-2033).

The global Hydrophobic Interaction Chromatography (HIC) market is experiencing robust growth, becoming essential for separating and purifying hydrophobic biomolecules. This expansion is primarily fueled by the increasing demand for biopharmaceuticals and the need for more efficient purification techniques. HIC stands out due to its high selectivity, mild operating conditions, and adaptability to various sample matrices. The rising interest in personalized medicine and the creation of innovative therapeutics further bolster market advancements. Additionally, innovations in HIC resins and column technologies, combined with enhancements in automation and process optimization, are significantly improving the efficiency and scalability of HIC processes. Consequently, the market is poised for continued growth, reflecting the broader expansion of the biopharmaceutical sector and the demand for effective purification solutions for intricate biomolecules.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global Hydrophobic Interaction Chromatography market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global Hydrophobic Interaction Chromatography Market Segments Analysis

Global Hydrophobic Interaction Chromatography Market is segmented by Product Type, Sample Type, End-User and region. Based on Product Type, the market is segmented into Resins, Columns and Instruments. Based on Sample Type, the market is segmented into Monoclonal Antibodies, Vaccines, Plasma Fractions and Other. Based on End-User, the market is segmented into Pharmaceutical and Biotechnology Companies, Contract Research Organizations (CROs) and Academic and Research Institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Global Hydrophobic Interaction Chromatography Market

The global Hydrophobic Interaction Chromatography (HIC) market is significantly driven by the rising demand for therapeutic proteins and monoclonal antibodies. As these biotherapeutics continue to gain importance in healthcare, the necessity for effective purification methods such as HIC becomes paramount in isolating and purifying these intricate molecules. HIC stands out due to its high selectivity and capacity, making it an indispensable technique in the biopharmaceutical manufacturing process. This trend illustrates the broader shift towards advanced purification technologies in response to the growing reliance on complex biologics in medical treatments, subsequently fueling the expansion of the HIC market.

Restraints in the Global Hydrophobic Interaction Chromatography Market

A significant barrier to the growth of the global hydrophobic interaction chromatography (HIC) market is the substantial financial investment required for both the deployment and upkeep of HIC systems. The complexity of the necessary equipment, alongside the cost of consumables and the need for specialized expertise, can be particularly burdensome. This challenge is magnified for smaller research laboratories and academic institutions that may lack sufficient funding. The high upfront costs, combined with ongoing operational expenses, can hinder the widespread adoption of HIC technology, especially in environments with limited resources, thereby impacting market expansion.

Market Trends of the Global Hydrophobic Interaction Chromatography Market

The Global Hydrophobic Interaction Chromatography (HIC) market is witnessing a significant trend towards increased utilization within the biopharmaceutical sector, largely fueled by the burgeoning demand for high-quality therapeutic proteins and monoclonal antibodies. HIC's unique capability to efficiently separate biomolecules based on their hydrophobic properties positions it as an essential technology in purification processes. As biopharmaceutical companies strive to comply with stringent regulatory standards regarding product safety and quality, the adoption of HIC is becoming indispensable. This trend underscores the need for advanced purification techniques capable of enhancing yield and efficacy, thus driving further growth in the HIC market.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2025
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis
• Case Studies
• Technology Advancement
• Regulatory Landscape
• Patent Analysis

Global Hydrophobic Interaction Chromatography Market Size by Product Type & CAGR (2026-2033)

• Market Overview
• Resins
  • Synthetic Resins
  • Natural Resins
• Columns
  • Pre-packed Columns
  • Empty Columns
• Instruments
  • Systems
  • Detectors

Global Hydrophobic Interaction Chromatography Market Size by Sample Type & CAGR (2026-2033)

• Market Overview
• Monoclonal Antibodies
• Vaccines
• Plasma Fractions
• Other

Global Hydrophobic Interaction Chromatography Market Size by End-User & CAGR (2026-2033)

• Market Overview
• Pharmaceutical and Biotechnology Companies
• Contract Research Organizations (CROs)
• Academic and Research Institutes

Global Hydrophobic Interaction Chromatography Market Size & CAGR (2026-2033)

• North America (Product Type, Sample Type, End-User)
  • US
  • Canada
• Europe (Product Type, Sample Type, End-User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Product Type, Sample Type, End-User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Product Type, Sample Type, End-User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Product Type, Sample Type, End-User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2025
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2025
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2023-2025)

Key Company Profiles

• Bio-Rad Laboratories, Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Thermo Fisher Scientific Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Sartorius AG (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Tosoh Corporation (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher Corporation (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies, Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Waters Corporation (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• PerkinElmer, Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Shimadzu Corporation (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GE Healthcare (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• JNC Corporation (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Works Technologies AB (Sweden)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Mitsubishi Chemical Corporation (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Daicel Corporation (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Avantor, Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Restek Corporation (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• KNAUER Wissenschaftliche Gerate GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Scion Instruments (Netherlands)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Gilson Incorporated (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations